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Select item 59150281.

HSPA5 negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer

Sun-Yong Kim, Hyo Jeong Kim, Haeng-Jun Kim, Dae Ho Kim, Jae Ho Han, Hyung Kwon Byeon, Keunho Lee, Chul-Ho Kim

Autophagy. 2018; 14(3): 385–403. Published online 2018 Feb 21. doi: 10.1080/15548627.2017.1414126

PMCID:: PMC5915028

Abstract Article PDF–2.3M

Select item 93042252.

MUL1‐RING recruits the substrate, p53‐TAD as a complex with UBE2D2–UB conjugate

Min‐Sung Lee, Sang‐Ok Lee, Joonhyeok Choi, Minju Ryu, Mi‐Kyung Lee, Ji‐Hun Kim, Eunha Hwang, Chong‐Kil Lee, Seung‐Wook Chi, Kyoung‐Seok Ryu

FEBS J. 2022 Jun; 289(12): 3568–3586. Published online 2022 Feb 4. doi: 10.1111/febs.16360

PMCID:: PMC9304225

Abstract Article PDF–8.6M

Select item 54278253.

The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity

Karine Doiron, Vanessa Goyon, Etienne Coyaud, Sanjeeva Rajapakse, Brian Raught, Heidi M. McBride

Sci Rep. 2017; 7: 107. Published online 2017 Mar 7. doi: 10.1038/s41598-017-00151-6

PMCID:: PMC5427825

Abstract Article PDF–2.0M

Select item 33436614.

Akt is negatively regulated by the MULAN E3 ligase

Seunghee Bae, Sun-Yong Kim, Jin Hyuk Jung, Yeongmin Yoon, Hwa Jun Cha, Hyunjin Lee, Karam Kim, Jongran Kim, In-Sook An, Jongdoo Kim, Hong-Duck Um, In-Chul Park, Su-Jae Lee, Seon Young Nam, Young-Woo Jin, Jae Ho Lee, Sungkwan An

Cell Res. 2012 May; 22(5): 873–885. Published online 2012 Mar 13. doi: 10.1038/cr.2012.38

PMCID:: PMC3343661

Abstract Article PDF–1.3M

Select item 22545065.

0610009K11Rik, a testis-specific and germ cell nuclear receptor-interacting protein

Heng Zhang, Leslie A. Denhard, Huaxin Zhou, Lan-Hsin Liu, Zi-Jian Lan

Biochem Biophys Res Commun. Author manuscript; available in PMC 2009 Feb 22.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Feb 22; 366(4): 898–904. Published online 2007 Dec 17. doi: 10.1016/j.bbrc.2007.12.035

PMCID:: PMC2254506

Abstract Article PDF–1.8M

Select item 21989406.

Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

Wei Li, Mario H. Bengtson, Axel Ulbrich, Akio Matsuda, Venkateshwar A. Reddy, Anthony Orth, Sumit K. Chanda, Serge Batalov, Claudio A. P. Joazeiro

PLoS One. 2008; 3(1): e1487. Published online 2008 Jan 23. doi: 10.1371/journal.pone.0001487

PMCID:: PMC2198940

Abstract Article PDF–1.1M

Select item 69944967.

Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein

Lucia Cilenti, Jacopo Di Gregorio, Camilla T. Ambivero, Thomas Andl, Ronglih Liao, Antonis S. Zervos

Sci Rep. 2020; 10: 1609. Published online 2020 Jan 31. doi: 10.1038/s41598-020-58484-8

PMCID:: PMC6994496

Abstract Article PDF–3.5M

Select item 69571148.

The RING domain of mitochondrial E3 ubiquitin ligase 1 and its complex with Ube2D2: crystallization and X-ray diffraction

Sang-Ok Lee, Chong-Kil Lee, Kyoung-Seok Ryu, Seung-Wook Chi

Acta Crystallogr F Struct Biol Commun. 2020 Jan 1; 76(Pt 1): 1–7. Published online 2020 Jan 1. doi: 10.1107/S2053230X19015395

PMCID:: PMC6957114

Abstract Article PDF–1.3M

Select item 32149109.

E3 ubiquitin ligase Hades negatively regulates the exonuclear function of p53

J H Jung, S Bae, J Y Lee, S R Woo, H J Cha, Y Yoon, K-S Suh, S-J Lee, I-C Park, Y-W Jin, K-H Lee, S An, J H Lee

Cell Death Differ. 2011 Dec; 18(12): 1865–1875. Published online 2011 May 20. doi: 10.1038/cdd.2011.57

PMCID:: PMC3214910

Abstract Article PDF–772K

Select item 553692210.

Control of mitochondrial homeostasis by endocytic regulatory proteins

Trey Farmer, James B. Reinecke, Shuwei Xie, Kriti Bahl, Naava Naslavsky, Steve Caplan

J Cell Sci. 2017 Jul 15; 130(14): 2359–2370. doi: 10.1242/jcs.204537

PMCID:: PMC5536922

Abstract Article

Select item 459067711.

Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy

Jie Li, Wei Qi, Guo Chen, Du Feng, Jinhua Liu, Biao Ma, Changqian Zhou, Chenglong Mu, Weilin Zhang, Quan Chen, Yushan Zhu

Autophagy. 2015 Aug; 11(8): 1216–1229. Published online 2015 Sep 14. doi: 10.1080/15548627.2015.1017180

PMCID:: PMC4590677

Abstract Article PDF–1.4M

Select item 272742612.

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

Emélie Braschi, Rodolfo Zunino, Heidi M McBride

EMBO Rep. 2009 Jul; 10(7): 748–754. Published online 2009 May 1. doi: 10.1038/embor.2009.86

PMCID:: PMC2727426

Abstract Article PDF–729K

Select item 404495213.

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

Jina Yun, Rajat Puri, Huan Yang, Michael A Lizzio, Chunlai Wu, Zu-Hang Sheng, Ming Guo

eLife. 2014; 3: e01958. Published online 2014 Jun 4. doi: 10.7554/eLife.01958

PMCID:: PMC4044952

Abstract Article PDF–5.2M

Select item 565626714.

Ubiquitination of STING at lysine 224 controls IRF3 activation

Guoxin Ni, Hiroyasu Konno, Glen N. Barber

Sci Immunol. Author manuscript; available in PMC 2017 Oct 25.

Published in final edited form as: Sci Immunol. 2017 May 5; 2(11): eaah7119. doi: 10.1126/sciimmunol.aah7119

PMCID:: PMC5656267

Abstract Article PDF–2.2M

Select item 532861915.

Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria

Janos Steffen, Ajay A. Vashisht, Jijun Wan, Joanna C. Jen, Steven M. Claypool, James A. Wohlschlegel, Carla M. Koehler

Mol Biol Cell. 2017 Mar 1; 28(5): 600–612. doi: 10.1091/mbc.E16-07-0545

PMCID:: PMC5328619

Abstract Article PDF–2.7M

Select item 603073016.

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

Julia Hülsmann, Bojana Kravic, Matthias Weith, Matthias Gstaiger, Ruedi Aebersold, Ben C. Collins, Hemmo Meyer

Mol Cell Proteomics. 2018 Jul; 17(7): 1295–1307. Published online 2018 Mar 29. doi: 10.1074/mcp.RA117.000471

PMCID:: PMC6030730

Abstract Article PDF–3.8M

Select item 315611017.

GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth

Bicheng Zhang, Jun Huang, Hong-Liang Li, Ting Liu, Yan-Yi Wang, Paul Waterman, Ai-Ping Mao, Liang-Guo Xu, Zhonghe Zhai, Depei Liu, Philippa Marrack, Hong-Bing Shu

Cell Res. Author manuscript; available in PMC 2011 Aug 15.

Published in final edited form as: Cell Res. 2008 Sep; 18(9): 900–910. doi: 10.1038/cr.2008.75

PMCID:: PMC3156110

Abstract Article PDF–1.2M

Select item 273665218.

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

Sjoerd J L van Wijk, Sjoerd J de Vries, Patrick Kemmeren, Anding Huang, Rolf Boelens, Alexandre M J J Bonvin, H Th Marc Timmers

Mol Syst Biol. 2009; 5: 295. Published online 2009 Aug 18. doi: 10.1038/msb.2009.55

Correction in:: Mol Syst Biol. 2009; 5: 317.

PMCID:: PMC2736652

Abstract Article PDF–5.6M

Select item 287256119.

An empirical framework for binary interactome mapping

Kavitha Venkatesan, Jean-François Rual, Alexei Vazquez, Ulrich Stelzl, Irma Lemmens, Tomoko Hirozane-Kishikawa, Tong Hao, Martina Zenkner, Xiaofeng Xin, Kwang-II Goh, Muhammed A Yildirim, Nicolas Simonis, Kathrin Heinzmann, Fana Gebreab, Julie M Sahalie, Sebiha Cevik, Christophe Simon, Anne-Sophie de Smet, Elizabeth Dann, Alex Smolyar, Arunachalam Vinayagam, Haiyuan Yu, David Szeto, Heather Borick, Amélie Dricot, Niels Klitgord, Ryan R Murray, Chenwei Lin, Maciej Lalowski, Jan Timm, Kirstin Rau, Charles Boone, Pascal Braun, Michael E Cusick, Frederick P Roth, David E Hill, Jan Tavernier, Erich E Wanker, Albert-László Barabási, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2010 May 18.

Published in final edited form as: Nat Methods. 2009 Jan; 6(1): 83–90. Published online 2008 Dec 7. doi: 10.1038/nmeth.1280

PMCID:: PMC2872561

Abstract Article PDF–1.0M

Select item 810809320.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

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