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Select item 109464371.

Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification

Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert Bonin, Levi L. Blazer, Jarrett J. Adams, Sachdev S. Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers

Development. 2024 Mar 1; 151(5): dev202545. Published online 2024 Mar 4. doi: 10.1242/dev.202545

PMCID:: PMC10946437

Abstract Article

Select item 95349572.

Aberrant Cholesterol Metabolism and Wnt/β‐Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth

Shaoqin Zheng, Jiahui Lin, Zhongqiu Pang, Hui Zhang, Yinuo Wang, Lanjing Ma, Haijiao Zhang, Xi Zhang, Maorong Chen, Xinjun Zhang, Chao Zhao, Jun Qi, Liu Cao, Min Wang, Xi He, Ren Sheng

Adv Sci (Weinh) 2022 Oct; 9(28): 2200750. Published online 2022 Aug 17. doi: 10.1002/advs.202200750

PMCID:: PMC9534957

Abstract Article PDF–6.1M

Select item 79860963.

FZD5 regulates cellular senescence in human mesenchymal stem/stromal cells

Seiko Harada, Yo Mabuchi, Jun Kohyama, Daisuke Shimojo, Sadafumi Suzuki, Yoshimi Kawamura, Daisuke Araki, Takashi Suyama, Masunori Kajikawa, Chihiro Akazawa, Hideyuki Okano, Yumi Matsuzaki

Stem Cells. 2021 Mar; 39(3): 318–330. Published online 2020 Dec 22. doi: 10.1002/stem.3317

PMCID:: PMC7986096

Abstract Article PDF–11M

Select item 78839314.

Confirming and expanding the phenotypes of FZD5 variants: Coloboma, inferior chorioretinal hypoplasia, and high myopia

Yi Jiang, Jiamin Ouyang, Shiqiang Li, Xueshan Xiao, Wenmin Sun, Qingjiong Zhang

Mol Vis. 2021; 27: 50–60. Published online 2021 Jan 20.

PMCID:: PMC7883931

Abstract Article PDF–10M

Select item 78530745.

Confirmation of FZD5 implication in a cohort of 50 patients with ocular coloboma

Marion Aubert-Mucca, Julie Pernin-Grandjean, Sébastien Marchasson, Veronique Gaston, Christophe Habib, Isabelle Meunier, Sabine Sigaudy, Josseline Kaplan, Olivier Roche, Danièle Denis, Pierre Bitoun, Damien Haye, Alain Verloes, Patrick Calvas, Nicolas Chassaing, Julie Plaisancié

Eur J Hum Genet. 2021 Jan; 29(1): 131–140. Published online 2020 Jul 31. doi: 10.1038/s41431-020-0695-8

PMCID:: PMC7853074

Abstract Article PDF–659K

Select item 77335996.

FZD5 contributes to TNBC proliferation, DNA damage repair and stemness

Yu Sun, Zhuo Wang, Lei Na, Dan Dong, Wei Wang, Chenghai Zhao

Cell Death Dis. 2020 Dec; 11(12): 1060. Published online 2020 Dec 12. doi: 10.1038/s41419-020-03282-3

PMCID:: PMC7733599

Abstract Article PDF–3.2M

Select item 74424897.

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling

Naotaka Tsutsumi, Somnath Mukherjee, Deepa Waghray, Claudia Y Janda, Kevin M Jude, Yi Miao, John S Burg, Nanda Gowtham Aduri, Anthony A Kossiakoff, Cornelius Gati, K Christopher Garcia

eLife. 2020; 9: e58464. Published online 2020 Aug 7. doi: 10.7554/eLife.58464

PMCID:: PMC7442489

Abstract Article PDF–4.9M

Select item 65306448.

Upregulation of FZD5 in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps by Epigenetic Modification

Jong-Yeup Kim, Min-Ji Cha, Young-Seon Park, Jaeku Kang, Jong-Joong Choi, Seung Min In, Dong-Kyu Kim

Mol Cells. 2019 Apr; 42(4): 345–355. Published online 2019 Apr 2. doi: 10.14348/molcells.2019.2418

PMCID:: PMC6530644

Abstract Article PDF–3.6M

Select item 90548489.

RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface

A-Ri Cho, Hee Jung Sul, Yoo Jin Kim, Bohyun Kim, Dae Young Zang

Sci Rep. 2022; 12: 7013. Published online 2022 Apr 29. doi: 10.1038/s41598-022-10868-8

PMCID:: PMC9054848

Abstract Article PDF–1.6M

Select item 789874510.

FZD5 prevents epithelial-mesenchymal transition in gastric cancer

Dan Dong, Lei Na, Kailing Zhou, Zhuo Wang, Yu Sun, Qianqian Zheng, Jian Gao, Chenghai Zhao, Wei Wang

Cell Commun Signal. 2021; 19: 21. Published online 2021 Feb 22. doi: 10.1186/s12964-021-00708-z

PMCID:: PMC7898745

Abstract Article PDF–7.2M

Select item 623149911.

Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B

Peng Chen, Liang Tao, Tianyu Wang, Jie Zhang, Aina He, Kwok-ho Lam, Zheng Liu, Xi He, Kay Perry, Min Dong, Rongsheng Jin

Science. Author manuscript; available in PMC 2019 May 11.

Published in final edited form as: Science. 2018 May 11; 360(6389): 664–669. doi: 10.1126/science.aar1999

PMCID:: PMC6231499

Abstract Article PDF–2.3M

Select item 522649612.

MicroRNA-224 inhibits proliferation and migration of breast cancer cells by down-regulating fizzled 5 expression

Feng Liu, Yang Liu, Jingling Shen, Guoqiang Zhang, Jiguang Han

Oncotarget. 2016 Aug 2; 7(31): 49130–49142. Published online 2016 May 31. doi: 10.18632/oncotarget.9734

PMCID:: PMC5226496

Abstract Article PDF–5.8M

Select item 415609313.

Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1ϵ and Frizzled5

Ondřej Bernatík, Kateřina Šedová, Carolin Schille, Ranjani Sri Ganji, Igor Červenka, Lukáš Trantírek, Alexandra Schambony, Zbyněk Zdráhal, Vítězslav Bryja

J Biol Chem. 2014 Aug 22; 289(34): 23520–23533. Published online 2014 Jul 3. doi: 10.1074/jbc.M114.590638

PMCID:: PMC4156093

Abstract Article PDF–2.6M

Select item 227734014.

Wnt7a Interaction with Fzd5 and Detection of Signaling Activation Using a Split eGFP

Kendra S. Carmon, David S. Loose

Biochem Biophys Res Commun. Author manuscript; available in PMC 2009 Apr 4.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Apr 4; 368(2): 285–291. Published online 2008 Jan 28. doi: 10.1016/j.bbrc.2008.01.088

PMCID:: PMC2277340

Abstract Article PDF–503K

Select item 1012400615.

A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA

Pei Lu, Jie Yang, Mao Li, Shanshan Wen, Tianzhe Zhang, Chenchao Yan, Ran Liu, Yu Xiao, Xinghuan Wang, Wei Jiang

Genome Biol. 2023; 24: 92. Published online 2023 Apr 24. doi: 10.1186/s13059-023-02925-w

PMCID:: PMC10124006

Abstract Article PDF–5.9M

Select item 846460416.

Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload

Yan Zou, Le Pan, Yi Shen, Xiang Wang, Chenxing Huang, Hao Wang, Xuejuan Jin, Chao Yin, Ying Wang, Jianguo Jia, Juying Qian, Yunzeng Zou, Hui Gong, Junbo Ge

Cell Death Dis. 2021 Oct; 12(10): 877. Published online 2021 Sep 25. doi: 10.1038/s41419-021-04152-2

PMCID:: PMC8464604

Abstract Article PDF–9.6M

Select item 631412517.

Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway

Yue Hua, Yilin Yang, Qian Li, Xinyu He, Wei Zhu, Jiyong Wang, Xiaoqing Gan

J Biol Chem. 2018 Dec 21; 293(51): 19710–19724. Published online 2018 Oct 25. doi: 10.1074/jbc.RA118.004434

PMCID:: PMC6314125

Abstract Article PDF–4.2M

Select item 620889818.

Endothelial loss of Fzd5 stimulates PKC/Ets1-mediated transcription of Angpt2 and Flt1

Maarten M. Brandt, Christian G. M. van Dijk, Ihsan Chrifi, Heleen M. Kool, Petra E. Bürgisser, Laura Louzao-Martinez, Jiayi Pei, Robbert J. Rottier, Marianne C. Verhaar, Dirk J. Duncker, Caroline Cheng

Angiogenesis. 2018; 21(4): 805–821. Published online 2018 May 29. doi: 10.1007/s10456-018-9625-6

PMCID:: PMC6208898

Abstract Article PDF–14M

Select item 532867219.

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions

Xin Zeng, He Huang, Keiko Tamai, Xinjun Zhang, Yuko Harada, Chika Yokota, Karla Almeida, Jianbo Wang, Brad Doble, Jim Woodgett, Anthony Wynshaw-Boris, Jen-Chieh Hsieh, Xi He

Development. Author manuscript; available in PMC 2017 Feb 27.

Published in final edited form as: Development. 2008 Jan; 135(2): 367–375. Published online 2007 Dec 12. doi: 10.1242/dev.013540

PMCID:: PMC5328672

Abstract Article PDF–1.4M

Select item 442092220.

Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling

Tadasuke Tsukiyama, Akimasa Fukui, Sayuri Terai, Yoichiro Fujioka, Keisuke Shinada, Hidehisa Takahashi, Terry P. Yamaguchi, Yusuke Ohba, Shigetsugu Hatakeyama

Mol Cell Biol. 2015 Jun; 35(11): 2007–2023. Prepublished online 2015 Mar 30. Published online 2015 May 5. doi: 10.1128/MCB.00159-15

PMCID:: PMC4420922

Abstract Article PDF–5.0M

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PMC Links for Gene (Select 7855) (45)
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Mus musculus cereblon (Crbn), transcript variant 1, mRNA
Mus musculus cereblon (Crbn), transcript variant 1, mRNA
gi|442734423|ref|NM_021449.3|

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