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Select item 95924971.

Significance analysis of PAX8 expression in endometrial carcinoma

Shan Hu, Hua Gan, Fengmei Yang

Medicine (Baltimore) 2022 Oct 21; 101(42): e31159. Published online 2022 Oct 21. doi: 10.1097/MD.0000000000031159

PMCID:: PMC9592497

Abstract Article PDF–1.6M

Select item 92428602.

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer

Saroor A. Patel, Shoko Hirosue, Paulo Rodrigues, Erika Vojtasova, Emma K. Richardson, Jianfeng Ge, Saiful E. Syafruddin, Alyson Speed, Evangelia K. Papachristou, David Baker, David Clarke, Stephenie Purvis, Ludovic Wesolowski, Anna Dyas, Leticia Castillon, Veronica Caraffini, Dóra Bihary, Cissy Yong, David J. Harrison, Grant D. Stewart, Mitchell J. Machiela, Mark P. Purdue, Stephen J. Chanock, Anne Y. Warren, Shamith A. Samarajiwa, Jason S. Carroll, Sakari Vanharanta

Nature. 2022; 606(7916): 999–1006. Published online 2022 Jun 8. doi: 10.1038/s41586-022-04809-8

PMCID:: PMC9242860

Abstract Article PDF–20M

Select item 82953183.

PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer

Emily Lee, Sarah Szvetecz, Ryan Polli, Angelo Grauel, Jayson Chen, Joyce Judge, Smita Jaiswal, Rie Maeda, Stephanie Schwartz, Bernd Voedisch, Mateusz Piksa, Chietara Japutra, Lingheswar Sadhasivam, Yiqin Wang, Ana Carrion, Sinan Isim, Jinsheng Liang, Thomas Nicholson, Hong Lei, Qing Fang, Michelle Steinkrauss, Dana Walker, Joel Wagner, Viviana Cremasco, Hui Qin Wang, Giorgio G. Galli, Brian Granda, Keith Mansfield, Quincey Simmons, Andrew Anh Nguyen, Nicole Vincent Jordan

Sci Rep. 2021; 11: 14841. Published online 2021 Jul 21. doi: 10.1038/s41598-021-93992-1

PMCID:: PMC8295318

Abstract Article PDF–7.6M

Select item 80939794.

Adipose‐derived mesenchymal stem cells induced PAX8 promotes ovarian cancer cell growth by stabilizing TAZ protein

Yijing Chu, Chengzhan Zhu, Qianqian Wang, Meixin Liu, Wei Wan, Jun Zhou, Rendong Han, Jing Yang, Wenqiang Luo, Chong Liu, Huansheng Zhou, Min Li, Fengsheng Yu, Yuanhua Ye

J Cell Mol Med. 2021 May; 25(9): 4434–4443. Published online 2021 Apr 8. doi: 10.1111/jcmm.16511

PMCID:: PMC8093979

Abstract Article PDF–1.4M

Select item 80265055.

Unraveling the mysteries of PAX8 in reproductive tract cancers

Daniele Chaves-Moreira, Patrice J. Morin, Ronny Drapkin

Cancer Res. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 806–810. Published online 2020 Dec 23. doi: 10.1158/0008-5472.CAN-20-3173

PMCID:: PMC8026505

Abstract Article PDF–629K

Select item 78961046.

Perturbations of genes essential for Müllerian duct and Wölffian duct development in Mayer-Rokitansky-Küster-Hauser syndrome

Na Chen, Sen Zhao, Angad Jolly, Lianlei Wang, Hongxin Pan, Jian Yuan, Shaoke Chen, André Koch, Congcong Ma, Weijie Tian, Ziqi Jia, Jia Kang, Lina Zhao, Chenglu Qin, Xin Fan, Katharina Rall, Zeynep Coban-Akdemir, Zefu Chen, Shalini Jhangiani, Ze Liang, Yuchen Niu, Xiaoxin Li, Zihui Yan, Yong Wu, Shuangshuang Dong, Chengcheng Song, Guixing Qiu, Shuyang Zhang, Pengfei Liu, Jennifer E. Posey, Feng Zhang, Guangnan Luo, Zhihong Wu, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study group, Jianzhong Su, Jianguo Zhang, Eugenia Y. Chen, Konstantinos Rouskas, Stavros Glentis, Flora Bacopoulou, Efthymios Deligeoroglou, George Chrousos, Stanislas Lyonnet, Michel Polak, Carla Rosenberg, Irene Dingeldein, Ximena Bonilla, Christelle Borel, Richard A. Gibbs, Jennifer E. Dietrich, Antigone S. Dimas, Stylianos E. Antonarakis, Sara Y. Brucker, James R. Lupski, Nan Wu, Lan Zhu

Am J Hum Genet. 2021 Feb 4; 108(2): 337–345. Published online 2021 Feb 4. doi: 10.1016/j.ajhg.2020.12.014

PMCID:: PMC7896104

Abstract Article PDF–1.2M

Select item 71816477.

Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer

Rosario I. Corona, Ji-Heui Seo, Xianzhi Lin, Dennis J. Hazelett, Jessica Reddy, Marcos A. S. Fonseca, Forough Abassi, Yvonne G. Lin, Paulette Y. Mhawech-Fauceglia, Sohrab P. Shah, David G. Huntsman, Alexander Gusev, Beth Y. Karlan, Benjamin P. Berman, Matthew L. Freedman, Simon A. Gayther, Kate Lawrenson

Nat Commun. 2020; 11: 2020. Published online 2020 Apr 24. doi: 10.1038/s41467-020-15951-0

PMCID:: PMC7181647

Abstract Article PDF–6.5M

Select item 67021568.

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

Melusine Bleu, Swann Gaulis, Rui Lopes, Kathleen Sprouffske, Verena Apfel, Sjoerd Holwerda, Marco Pregnolato, Umut Yildiz, Valentina Cordoʹ, Antonella F. M. Dost, Judith Knehr, Walter Carbone, Felix Lohmann, Charles Y. Lin, James E. Bradner, Audrey Kauffmann, Luca Tordella, Guglielmo Roma, Giorgio G. Galli

Nat Commun. 2019; 10: 3739. Published online 2019 Aug 20. doi: 10.1038/s41467-019-11672-1

PMCID:: PMC6702156

Abstract Article PDF–1.8M

Select item 65330839.

PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors

Kaixuan Shi, Xia Yin, Mei-Chun Cai, Ying Yan, Chenqiang Jia, Pengfei Ma, Shengzhe Zhang, Zhenfeng Zhang, Zhenyu Gu, Meiying Zhang, Wen Di, Guanglei Zhuang

eLife. 2019; 8: e44306. Published online 2019 May 3. doi: 10.7554/eLife.44306

PMCID:: PMC6533083

Abstract Article PDF–6.8M

Select item 536510510.

Expression quantitative trait loci for PAX8 contributes to the prognosis of hepatocellular carcinoma

Shijie Ma, Jianshui Yang, Ci Song, Zijun Ge, Jing Zhou, Guoxin Zhang, Zhibin Hu

PLoS One. 2017; 12(3): e0173700. Published online 2017 Mar 24. doi: 10.1371/journal.pone.0173700

PMCID:: PMC5365105

Abstract Article PDF–1.1M

Select item 535243411.

Identification and characterization of novel PAX8 mutations in Congenital Hypothyroidism(CH) in a Chinese population

Shiguo Liu, Xueqin Wang, Hui Zou, Yinlin Ge, Fang Wang, Yangang Wang, Shengli Yan, Hongfei Xia, Mingzhao Xing

Oncotarget. 2017 Jan 31; 8(5): 8707–8716. Published online 2017 Jan 2. doi: 10.18632/oncotarget.14419

PMCID:: PMC5352434

Abstract Article PDF–3.3M

Select item 531896912.

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

Siddhartha P Kar, Emily Adler, Jonathan Tyrer, Dennis Hazelett, Hoda Anton-Culver, Elisa V Bandera, Matthias W Beckmann, Andrew Berchuck, Natalia Bogdanova, Louise Brinton, Ralf Butzow, Ian Campbell, Karen Carty, Jenny Chang-Claude, Linda S Cook, Daniel W Cramer, Julie M Cunningham, Agnieszka Dansonka-Mieszkowska, Jennifer Anne Doherty, Thilo Dörk, Matthias Dürst, Diana Eccles, Peter A Fasching, James Flanagan, Aleksandra Gentry-Maharaj, Rosalind Glasspool, Ellen L Goode, Marc T Goodman, Jacek Gronwald, Florian Heitz, Michelle A T Hildebrandt, Estrid Høgdall, Claus K Høgdall, David G Huntsman, Allan Jensen, Beth Y Karlan, Linda E Kelemen, Lambertus A Kiemeney, Susanne K Kjaer, Jolanta Kupryjanczyk, Diether Lambrechts, Douglas A Levine, Qiyuan Li, Jolanta Lissowska, Karen H Lu, Jan Lubiński, Leon F A G Massuger, Valerie McGuire, Iain McNeish, Usha Menon, Francesmary Modugno, Alvaro N Monteiro, Kirsten B Moysich, Roberta B Ness, Heli Nevanlinna, James Paul, Celeste L Pearce, Tanja Pejovic, Jennifer B Permuth, Catherine Phelan, Malcolm C Pike, Elizabeth M Poole, Susan J Ramus, Harvey A Risch, Mary Anne Rossing, Helga B Salvesen, Joellen M Schildkraut, Thomas A Sellers, Mark Sherman, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa Southey, Kathryn L Terry, Shelley S Tworoger, Christine Walsh, Nicolas Wentzensen, Alice S Whittemore, Anna H Wu, Hannah Yang, Wei Zheng, Argyrios Ziogas, Matthew L Freedman, Simon A Gayther, Paul D P Pharoah, Kate Lawrenson

Br J Cancer. 2017 Feb 14; 116(4): 524–535. Published online 2017 Jan 19. doi: 10.1038/bjc.2016.426

PMCID:: PMC5318969

Abstract Article PDF–232K

Select item 517310613.

Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma

Tiziana de Cristofaro, Tina Di Palma, Amata Amy Soriano, Antonella Monticelli, Ornella Affinito, Sergio Cocozza, Mariastella Zannini

Oncotarget. 2016 Jul 5; 7(27): 41929–41947. Published online 2016 May 31. doi: 10.18632/oncotarget.9740

PMCID:: PMC5173106

Abstract Article PDF–6.8M

Select item 506163514.

A Novel Mutation (S54C) of the PAX8 Gene in a Family with Congenital Hypothyroidism and High Proportion of Affected Individuals

Panudda Srichomkwun, Osnat Admoni, Samuel Refetoff, Liat de Vries

Horm Res Paediatr. Author manuscript; available in PMC 2017 May 21.

Published in final edited form as: Horm Res Paediatr. 2016; 86(2): 137–142. Published online 2016 May 21. doi: 10.1159/000445891

PMCID:: PMC5061635

Abstract Article PDF–1.2M

Select item 504950915.

Pair Box 8 (PAX8) protein expression in high grade, late stage (stages III and IV) ovarian serous carcinoma

Paulette Mhawech-Fauceglia, Dan Wang, Damanzoopinder Samrao, Heidi Godoy, Faith Ough, Song Liu, Tanja Pejovic, Shashikant Lele

Gynecol Oncol. Author manuscript; available in PMC 2016 Oct 4.

Published in final edited form as: Gynecol Oncol. 2012 Oct; 127(1): 198–201. Published online 2012 Jun 15. doi: 10.1016/j.ygyno.2012.06.012

PMCID:: PMC5049509

Abstract Article PDF–1.1M

Select item 495120816.

PAX8 Expression in Ovarian Surface Epithelial Cells

Emily Adler, Paulette Mhawech-Fauceglia, Simon A Gayther, Kate Lawrenson

Hum Pathol. Author manuscript; available in PMC 2016 Jul 19.

Published in final edited form as: Hum Pathol. 2015 Jul; 46(7): 948–956. Published online 2015 Apr 15. doi: 10.1016/j.humpath.2015.03.017

PMCID:: PMC4951208

Abstract Article PDF–653K

Select item 488915417.

Expression of PAX8 Target Genes in Papillary Thyroid Carcinoma

Francesca Rosignolo, Marialuisa Sponziello, Cosimo Durante, Cinzia Puppin, Catia Mio, Federica Baldan, Carla Di Loreto, Diego Russo, Sebastiano Filetti, Giuseppe Damante

PLoS One. 2016; 11(6): e0156658. Published online 2016 Jun 1. doi: 10.1371/journal.pone.0156658

PMCID:: PMC4889154

Abstract Article PDF–7.2M

Select item 463768718.

A De novo PAX8 mutation in a Chinese child with congenital thyroid dysgenesis

Hui Zou, Jian Chai, Shiguo Liu, Hongwei Zang, Xiaoxia Yu, Liping Tian, Huichao Li, Bingjuan Han

Int J Clin Exp Pathol. 2015; 8(9): 11434–11439. Published online 2015 Sep 1.

PMCID:: PMC4637687

Abstract Article PDF–543K

Select item 448404319.

Differentiating primary and extragenital metastatic mucinous ovarian tumours: an algorithm combining PAX8 with tumour size and laterality

Ajin Hu, Hongwei Li, Letian Zhang, Caixia Ren, Yuxiang Wang, Yan Liu, Congrong Liu

J Clin Pathol. 2015 Jul; 68(7): 522–528. Published online 2015 Mar 31. doi: 10.1136/jclinpath-2015-202951

PMCID:: PMC4484043

Abstract Article PDF–2.1M

Select item 442905420.

PAX-8 expression in renal tumours and distant sites: A useful marker of primary and metastatic renal cell carcinoma?

Meaghan L Barr, Lucia B Jilaveanu, Robert L Camp, Adebowale J Adeniran, Harriet M Kluger, Brian Shuch

J Clin Pathol. Author manuscript; available in PMC 2015 May 12.

Published in final edited form as: J Clin Pathol. 2015 Jan; 68(1): 12–17. Published online 2014 Oct 14. doi: 10.1136/jclinpath-2014-202259

PMCID:: PMC4429054

Abstract Article PDF–672K

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