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Select item 106251101.

YWHAG Deficiency Disrupts the EMT‐Associated Network to Induce Oxidative Cell Death and Prevent Metastasis

Jeannie Xue Ting Lee, Wei Ren Tan, Zun Siong Low, Jia Qi Lee, Damien Chua, Wisely Duan Chi Yeo, Benedict See, Marcus Ivan Gerard Vos, Tomohiko Yasuda, Sachiyo Nomura, Hong Sheng Cheng, Nguan Soon Tan

Adv Sci (Weinh) 2023 Nov; 10(31): 2301714. Published online 2023 Sep 27. doi: 10.1002/advs.202301714

PMCID:: PMC10625110

Abstract Article PDF–4.2M

Select item 95691272.

A heterozygous missense variant in the YWHAG gene causing developmental and epileptic encephalopathy 56 in a Chinese family

Zhi Yi, Zhenfeng Song, Jiao Xue, Chengqing Yang, Fei Li, Hua Pan, Xuan Feng, Ying Zhang, Hong Pan

BMC Med Genomics. 2022; 15: 216. Published online 2022 Oct 15. doi: 10.1186/s12920-022-01377-8

PMCID:: PMC9569127

Abstract Article PDF–1.2M

Select item 48905933.

14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression

Amitabha Mukhopadhyay, Lalit Sehgal, Arunabha Bose, Anushree Gulvady, Parijat Senapati, Rahul Thorat, Srikanta Basu, Khyati Bhatt, Amol S. Hosing, Renu Balyan, Lalit Borde, Tapas K. Kundu, Sorab N. Dalal

Sci Rep. 2016; 6: 26580. Published online 2016 Jun 2. doi: 10.1038/srep26580

PMCID:: PMC4890593

Abstract Article PDF–3.3M

Select item 35279174.

Activation of Phosphatidylinositol 3-Kinase (PI3K) and Mitogen-activated Protein Kinase (MAPK) Signaling and the Consequent Induction of Transformation by Overexpressed 14-3-3γ Protein Require Specific Amino Acids within 14-3-3γ N-terminal Variable Region II

Vijayababu M. Radhakrishnan, Charles W. Putnam, Jesse D. Martinez

J Biol Chem. 2012 Dec 21; 287(52): 43300–43311. Published online 2012 Oct 31. doi: 10.1074/jbc.M112.397877

PMCID:: PMC3527917

Abstract Article PDF–2.2M

Select item 35066625.

The Peripheral Binding of 14-3-3γ to Membranes Involves Isoform-Specific Histidine Residues

Helene J. Bustad, Lars Skjaerven, Ming Ying, Øyvind Halskau, Anne Baumann, David Rodriguez-Larrea, Miguel Costas, Jarl Underhaug, Jose M. Sanchez-Ruiz, Aurora Martinez

PLoS One. 2012; 7(11): e49671. Published online 2012 Nov 26. doi: 10.1371/journal.pone.0049671

PMCID:: PMC3506662

Abstract Article PDF–1.4M

Select item 96838616.

Human 14-3-3 Proteins Site-selectively Bind the Mutational Hotspot Region of SARS-CoV-2 Nucleoprotein Modulating its Phosphoregulation

Kristina V. Tugaeva, Andrey A. Sysoev, Anna A. Kapitonova, Jake L.R. Smith, Phillip Zhu, Richard B. Cooley, Alfred A. Antson, Nikolai N. Sluchanko

J Mol Biol. 2023 Jan 30; 435(2): 167891. Published online 2022 Nov 24. doi: 10.1016/j.jmb.2022.167891

PMCID:: PMC9683861

Abstract Article PDF–2.7M

Select item 83769277.

14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites

Matej Horvath, Olivia Petrvalska, Petr Herman, Veronika Obsilova, Tomas Obsil

Commun Biol. 2021; 4: 986. Published online 2021 Aug 19. doi: 10.1038/s42003-021-02518-y

PMCID:: PMC8376927

Abstract Article PDF–4.6M

Select item 78637658.

The Mechanism of SARS-CoV-2 Nucleocapsid Protein Recognition by the Human 14-3-3 Proteins

Kristina V. Tugaeva, Dorothy E.D.P. Hawkins, Jake L.R. Smith, Oliver W. Bayfield, De-Sheng Ker, Andrey A. Sysoev, Oleg I. Klychnikov, Alfred A. Antson, Nikolai N. Sluchanko

J Mol Biol. 2021 Apr 16; 433(8): 166875. doi: 10.1016/j.jmb.2021.166875

PMCID:: PMC7863765

Abstract Article PDF–2.6M

Select item 65268399.

YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization

Yang Xu, Jinqi Ren, Xiaolong He, Han Chen, Taotao Wei, Wei Feng

Autophagy. 2019; 15(6): 1017–1030. Published online 2019 Jan 27. doi: 10.1080/15548627.2019.1569928

PMCID:: PMC6526839

Abstract Article PDF–3.2M

Select item 570109210.

Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial–mesenchymal transition by inducing 14-3-3γ expression

Z Teo, M K Sng, J S K Chan, M M K Lim, Y Li, L Li, T Phua, J Y H Lee, Z W Tan, P Zhu, N S Tan

Oncogene. 2017 Nov 16; 36(46): 6408–6419. Published online 2017 Jul 24. doi: 10.1038/onc.2017.244

PMCID:: PMC5701092

Abstract Article PDF–5.0M

Select item 554441711.

De Novo Mutations in YWHAG Cause Early-Onset Epilepsy

Ilaria Guella, Marna B. McKenzie, Daniel M. Evans, Sarah E. Buerki, Eric B. Toyota, Margot I. Van Allen, Epilepsy Genomics Study, Mohnish Suri, Frances Elmslie, Deciphering Developmental Disorders Study, Marleen E.H. Simon, Koen L.I. van Gassen, Delphine Héron, Boris Keren, Caroline Nava, Mary B. Connolly, Michelle Demos, Matthew J. Farrer

Am J Hum Genet. 2017 Aug 3; 101(2): 300–310. Published online 2017 Aug 3. doi: 10.1016/j.ajhg.2017.07.004

PMCID:: PMC5544417

Abstract Article PDF–1.5M

Select item 474219512.

Deubiquitinating enzyme USP37 regulating oncogenic function of 14-3-3γ

Jin-Ock Kim, So-Ra Kim, Key-Hwan Lim, Jun-Hyun Kim, Brijesh Ajjappala, Hey-Jin Lee, Jee-In Choi, Kwang-Hyun Baek

Oncotarget. 2015 Nov 3; 6(34): 36551–36576. Published online 2015 Sep 25. doi: 10.18632/oncotarget.5336

PMCID:: PMC4742195

Abstract Article PDF–12M

Select item 412573413.

Phosphorylation Dependence and Stoichiometry of the Complex Formed by Tyrosine Hydroxylase and 14-3-3γ

Rune Kleppe, Sara Rosati, Ana Jorge-Finnigan, Sara Alvira, Sadaf Ghorbani, Jan Haavik, José María Valpuesta, Albert J. R. Heck, Aurora Martinez

Mol Cell Proteomics. 2014 Aug; 13(8): 2017–2030. Published online 2014 Jun 19. doi: 10.1074/mcp.M113.035709

PMCID:: PMC4125734

Abstract Article PDF–1.1M

Select item 387224214.

The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes

Åge Aleksander Skjevik, Mauro Mileni, Anne Baumann, Øyvind Halskau, Knut Teigen, Raymond C. Stevens, Aurora Martinez

J Mol Biol. Author manuscript; available in PMC 2015 Jan 9.

Published in final edited form as: J Mol Biol. 2014 Jan 9; 426(1): 10.1016/j.jmb.2013.09.012. Published online 2013 Sep 17. doi: 10.1016/j.jmb.2013.09.012