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Items: 1 to 20 of 149

1.
UBTF tandem duplications define a distinct subtype of adult de novo acute myeloid leukemia
Nicolas Duployez, Loïc Vasseur, Rathana Kim, Laëtitia Largeaud, Marie Passet, Anaïs L’Haridon, Pierre Lemaire, Laurène Fenwarth, Sandrine Geffroy, Nathalie Helevaut, Karine Celli‑Lebras, Lionel Adès, Delphine Lebon, Céline Berthon, Alice Marceau-Renaut, Meyling Cheok, Juliette Lambert, Christian Récher, Emmanuel Raffoux, Jean-Baptiste Micol, Arnaud Pigneux, Claude Gardin, Eric Delabesse, Jean Soulier, Mathilde Hunault, Hervé Dombret, Raphael Itzykson, Emmanuelle Clappier, Claude Preudhomme
Leukemia. 2023; 37(6): 1245–1253. Published online 2023 Apr 21. doi: 10.1038/s41375-023-01906-z
PMCID:
PMC10244165
AbstractArticlePDF–2.9M
2.
UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome
Julia-Annabell Georgi, Sebastian Stasik, Jan-Niklas Eckardt, Sven Zukunft, Marita Hartwig, Christoph Röllig, Jan Moritz Middeke, Uta Oelschlägel, Utz Krug, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan W. Krause, Mathias Hänel, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Carsten Müller-Tidow, Uwe Platzbecker, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Frank Kroschinsky, Christian Thiede, Study Alliance Leukemia (SAL)
Blood Cancer J. 2023 Dec; 13(1): 88. Published online 2023 May 26. doi: 10.1038/s41408-023-00858-y
PMCID:
PMC10220021
AbstractArticlePDF–2.5M
3.
Internal Associations of the Acidic Region of Upstream Binding Factor Control Its Nucleolar Localization
Shuhei Ueshima, Kyosuke Nagata, Mitsuru Okuwaki
Mol Cell Biol. 2017 Nov 15; 37(22): e00218-17. Prepublished online 2017 Sep 5. Published online 2017 Oct 27. doi: 10.1128/MCB.00218-17
PMCID:
PMC5660467
AbstractArticlePDF–4.6M
4.
Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments
Nigel D. Stow, Vanessa C. Evans, David A. Matthews
J Gen Virol. 2009 Jan; 90(Pt 1): 69–73. doi: 10.1099/vir.0.006353-0
PMCID:
PMC2885023
AbstractArticlePDF–452K
5.
Asymmetrical distribution of the transcriptionally competent NORs in mitosis
Markéta Kalmárová, Lubomír Kováčik, Alexey Popov, Sánchez Pilar Testillano, Evgeny Smirnov
J Struct Biol. 2008 Jul; 163(1-3): 40–44. doi: 10.1016/j.jsb.2008.04.002
PMCID:
PMC2475583
AbstractArticle
6.
UBF activates RNA polymerase I transcription by stimulating promoter escape
Kostya I Panov, J Karsten Friedrich, Jackie Russell, Joost C B M Zomerdijk
EMBO J. 2006 Jul 26; 25(14): 3310–3322. Published online 2006 Jul 6. doi: 10.1038/sj.emboj.7601221
PMCID:
PMC1523182
AbstractArticlePDF–543K
7.
UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery
Christine Mais, Jane E. Wright, José-Luis Prieto, Samantha L. Raggett, Brian McStay
Genes Dev. 2005 Jan 1; 19(1): 50–64. doi: 10.1101/gad.310705
PMCID:
PMC540225
AbstractArticlePDF–619K
8.
Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway
Lamis Yehia, Supriya Jindal, Anton A Komar, Charis Eng
Hum Mol Genet. 2018 Sep 15; 27(18): 3154–3164. Published online 2018 Jun 8. doi: 10.1093/hmg/ddy226
PMCID:
PMC6121187
AbstractArticlePDF–1.3M
9.
A recurrent de novo missense mutation in UBTF causes developmental neuroregression
Camilo Toro, Roderick T Hori, May Christine V Malicdan, Cynthia J Tifft, Amy Goldstein, William A Gahl, David R Adams, Harper B Fauni, Lynne A Wolfe, Jianfeng Xiao, Mohammad M Khan, Jun Tian, Kevin A Hope, Lawrence T Reiter, Michel G Tremblay, Tom Moss, Alexis L Franks, Chris Balak, C4RCD Research Group, Mark S LeDoux
Hum Mol Genet. 2018 Feb 15; 27(4): 691–705. Published online 2018 Jan 2. doi: 10.1093/hmg/ddx435
Correction in:
Hum Mol Genet. 2018 Apr 1; 27(7): 1310.
PMCID:
PMC5886272
AbstractArticlePDF–1.0M
10.
Heterozygous De Novo UBTF Gain-of-Function Variant Is Associated with Neurodegeneration in Childhood
Simon Edvardson, Claudia M. Nicolae, Pankaj B. Agrawal, Cyril Mignot, Katelyn Payne, Asuri Narayan Prasad, Chitra Prasad, Laurie Sadler, Caroline Nava, Thomas E. Mullen, Amber Begtrup, Berivan Baskin, Zöe Powis, Avraham Shaag, Boris Keren, George-Lucian Moldovan, Orly Elpeleg
Am J Hum Genet. 2017 Aug 3; 101(2): 267–273. Published online 2017 Aug 3. doi: 10.1016/j.ajhg.2017.07.002
PMCID:
PMC5544390
AbstractArticlePDF–861K
11.
TP53INP2/DOR, a mediator of cell autophagy, promotes rDNA transcription via facilitating the assembly of the POLR1/RNA polymerase I preinitiation complex at rDNA promoters
Yinfeng Xu, Wei Wan, Xin Shou, Rui Huang, Zhiyuan You, Yanhong Shou, Lingling Wang, Tianhua Zhou, Wei Liu
Autophagy. 2016 Jul; 12(7): 1118–1128. Published online 2016 May 12. doi: 10.1080/15548627.2016.1175693
PMCID:
PMC4990990
AbstractArticlePDF–1.3M
12.
Nuclear Localization and Functional Characteristics of Voltage-gated Potassium Channel Kv1.3
Soo Hwa Jang, Jun Kyu Byun, Won-Il Jeon, Seon Young Choi, Jin Park, Bo Hyung Lee, Ji Eun Yang, Jin Bong Park, Scott M. O'Grady, Dae-Yong Kim, Pan Dong Ryu, Sang-Woo Joo, So Yeong Lee
J Biol Chem. 2015 May 15; 290(20): 12547–12557. Published online 2015 Mar 31. doi: 10.1074/jbc.M114.561324
PMCID:
PMC4432276
AbstractArticlePDF–1.7M
13.
A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes
Elaine Sanij, Jeannine Diesch, Analia Lesmana, Gretchen Poortinga, Nadine Hein, Grace Lidgerwood, Donald P. Cameron, Jason Ellul, Gregory J. Goodall, Lee H. Wong, Amardeep S. Dhillon, Nourdine Hamdane, Lawrence I. Rothblum, Richard B. Pearson, Izhak Haviv, Tom Moss, Ross D. Hannan
Genome Res. 2015 Feb; 25(2): 201–212. doi: 10.1101/gr.176115.114
PMCID:
PMC4315294
AbstractArticlePDF–1.3M
14.
TBP-TAF Complex SL1 Directs RNA Polymerase I Pre-initiation Complex Formation and Stabilizes Upstream Binding Factor at the rDNA Promoter
J. Karsten Friedrich, Kostya I. Panov, Pavel Cabart, Jackie Russell, Joost C. B. M. Zomerdijk
J Biol Chem. Author manuscript; available in PMC 2013 Dec 11.
Published in final edited form as: J Biol Chem. 2005 Aug 19; 280(33): 10.1074/jbc.M501595200. Published online 2005 Jun 21. doi: 10.1074/jbc.M501595200
PMCID:
PMC3858828
AbstractArticlePDF–1.8M
15.
Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease
J Lee, Y J Hwang, J H Boo, D Han, O K Kwon, K Todorova, N W Kowall, Y Kim, H Ryu
Cell Death Differ. 2011 Nov; 18(11): 1726–1735. Published online 2011 May 6. doi: 10.1038/cdd.2011.38
PMCID:
PMC3154516
AbstractArticlePDF–730K
16.
hALP, A Novel Transcriptional U Three Protein (t-UTP), Activates RNA Polymerase I Transcription by Binding and Acetylating the Upstream Binding Factor (UBF)
Ruirui Kong, Liangliang Zhang, Lelin Hu, Qunhui Peng, Wei Han, Xiaojuan Du, Yang Ke
J Biol Chem. 2011 Mar 4; 286(9): 7139–7148. Published online 2010 Dec 22. doi: 10.1074/jbc.M110.173393
PMCID:
PMC3044971
AbstractArticlePDF–2.0M
17.
Regulation of Nucleolar Chromatin by B23/Nucleophosmin Jointly Depends upon Its RNA Binding Activity and Transcription Factor UBF
Miharu Hisaoka, Shuhei Ueshima, Kensaku Murano, Kyosuke Nagata, Mitsuru Okuwaki
Mol Cell Biol. 2010 Oct; 30(20): 4952–4964. Published online 2010 Aug 16. doi: 10.1128/MCB.00299-10
PMCID:
PMC2950543
AbstractArticlePDF–2.1M
18.
Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor
J Exp Med. 1991 Nov 1; 174(5): 1239–1244. doi: 10.1084/jem.174.5.1239
PMCID:
PMC2119007
SummaryPDF–931K
19.
The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcription.
C J Liu, H Wang, P Lengyel
EMBO J. 1999 May 17; 18(10): 2845–2854. doi: 10.1093/emboj/18.10.2845
PMCID:
PMC1171365
SummaryPDF–323K
20.
Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcription
Kalipso Halkidou, Ian R. Logan, Susan Cook, David E. Neal, Craig N. Robson
Nucleic Acids Res. 2004; 32(5): 1654–1665. Published online 2004 Mar 11. doi: 10.1093/nar/gkh296
PMCID:
PMC390321
AbstractArticlePDF–303K

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