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Select item 111587531.

Vaccination with multiple peptides derived from novel cancer‐testis antigens can induce specific T‐cell responses and clinical responses in advanced esophageal cancer

Koji Kono, Yoshiki Mizukami, Yataro Daigo, Atsushi Takano, Ken Masuda, Koji Yoshida, Takuya Tsunoda, Yoshihiko Kawaguchi, Yusuke Nakamura, Hideki Fujii

Cancer Sci. 2009 Aug; 100(8): 1502–1509. Published online 2009 Apr 27. doi: 10.1111/j.1349-7006.2009.01200.x

PMCID:: PMC11158753

Abstract Article PDF–9.1M

Select item 111580972.

Detection of novel cancer‐testis antigen‐specific T‐cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma

Yoshiki Mizukami, Koji Kono, Yataro Daigo, Atsushi Takano, Takuya Tsunoda, Yoshihiko Kawaguchi, Yusuke Nakamura, Hideki Fujii

Cancer Sci. 2008 Jul; 99(7): 1448–1454. Published online 2008 Apr 30. doi: 10.1111/j.1349-7006.2008.00844.x

PMCID:: PMC11158097

Abstract Article PDF–456K

Select item 105997543.

TTK is a potential regulator of tumor progression correlated with dedifferentiation and immune cell infiltration in papillary thyroid cancer

Jun-Jie Ma, Cheng Xiang, Jian-Wei Wang

Aging (Albany NY) 2023 Oct 15; 15(19): 10607–10626. Published online 2023 Oct 6. doi: 10.18632/aging.205100

PMCID:: PMC10599754

Abstract Article PDF–4.0M

Select item 92902164.

TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma

Jian Yu, Ge Gao, Xiangpin Wei, Yang Wang

BMC Cancer. 2022; 22: 786. Published online 2022 Jul 18. doi: 10.1186/s12885-022-09899-1

PMCID:: PMC9290216

Abstract Article PDF–6.8M

Select item 82816405.

Overexpressed MPS-1 contributes to endometrioma development through the NF-κB signaling pathway

Yang Liu, Junyan Ma, Liqi Zhang, Jun Lin, Xiaohua Liu

Reprod Biol Endocrinol. 2021; 19: 111. Published online 2021 Jul 15. doi: 10.1186/s12958-021-00796-z

PMCID:: PMC8281640

Abstract Article PDF–1.3M

Select item 75386836.

Bioinformatics analysis and experimental validation of TTK as a biomarker for prognosis in non-small cell lung cancer

Jiajia Chen, Rong Wu, Ying Xuan, Min Jiang, Yuecan Zeng

Biosci Rep. 2020 Oct 30; 40(10): BSR20202711. Published online 2020 Oct 6. doi: 10.1042/BSR20202711

PMCID:: PMC7538683

Abstract Article PDF–3.5M

Select item 73717067.

Inhibition of mitotic kinase Mps1 promotes cell death in neuroblastoma

Sonia Simon Serrano, Wondossen Sime, Yasmin Abassi, Renée Daams, Ramin Massoumi, Mohamed Jemaà

Sci Rep. 2020; 10: 11997. Published online 2020 Jul 20. doi: 10.1038/s41598-020-68829-y

PMCID:: PMC7371706

Abstract Article PDF–5.3M

Select item 69941338.

TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination

Benjamin C. Chandler, Leah Moubadder, Cassandra L. Ritter, Meilan Liu, Meleah Cameron, Kari Wilder-Romans, Amanda Zhang, Andrea M. Pesch, Anna R. Michmerhuizen, Nicole Hirsh, Marlie Androsiglio, Tanner Ward, Eric Olsen, Yashar S. Niknafs, Sofia Merajver, Dafydd G. Thomas, Powel H. Brown, Theodore S. Lawrence, Shyam Nyati, Lori J. Pierce, Arul Chinnaiyan, Corey Speers

J Clin Invest. 2020 Feb 3; 130(2): 958–973. Published online 2020 Jan 21. doi: 10.1172/JCI130435

PMCID:: PMC6994133

Abstract Article PDF–11M

Select item 65904249.

A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop

Jacomina C. Roorda, Robbie P. Joosten, Anastassis Perrakis, Yoshitaka Hiruma

Proteins. 2019 Apr; 87(4): 348–352. Published online 2019 Jan 8. doi: 10.1002/prot.25651

PMCID:: PMC6590424

Abstract Article PDF–2.8M

Select item 611985910.

Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis

Spyridon T. Pachis, Geert J. P. L. Kops

Open Biol. 2018 Aug; 8(8): 180109. Published online 2018 Aug 15. doi: 10.1098/rsob.180109

PMCID:: PMC6119859

Abstract Article PDF–741K

Select item 575443911.

Whole-Exome Sequencing Identifies the 6q12-q16 Linkage Region and a Candidate Gene, TTK, for Pulmonary Nontuberculous Mycobacterial Disease

Fei Chen, Eva P. Szymanski, Kenneth N. Olivier, Xinyue Liu, Hervé Tettelin, Steven M. Holland, Priya Duggal

Am J Respir Crit Care Med. 2017 Dec 15; 196(12): 1599–1604. Published online 2017 Dec 15. doi: 10.1164/rccm.201612-2479OC

PMCID:: PMC5754439

Abstract Article PDF–568K

Select item 569083812.

Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma

Agata Szymiczek, Michele Carbone, Sandra Pastorino, Andrea Napolitano, Mika Tanji, Michael Minaai, Ian Pagano, Jacqueline M. Mason, Harvey I. Pass, Mark R. Bray, Tak W. Mak, Haining Yang

Oncogene. Author manuscript; available in PMC 2018 Jan 31.

Published in final edited form as: Oncogene. 2017 Nov 16; 36(46): 6501–6507. Published online 2017 Jul 31. doi: 10.1038/onc.2017.266

PMCID:: PMC5690838

Abstract Article PDF–2.0M

Select item 558284213.

Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures

Yoshitaka Hiruma, Andre Koch, Nazila Hazraty, Foteini Tsakou, René H. Medema, Robbie P. Joosten, Anastassis Perrakis

J Biol Chem. 2017 Sep 1; 292(35): 14496–14504. Published online 2017 Jul 18. doi: 10.1074/jbc.M117.783555

PMCID:: PMC5582842

Abstract Article PDF–3.1M

Select item 556929414.

Threonine and tyrosine kinase may serve as a prognostic biomarker for gallbladder cancer

Yuan Xie, Jian-Zhen Lin, An-Qiang Wang, Wei-Yu Xu, Jun-Yu Long, Yu-Feng Luo, Jie Shi, Zhi-Yong Liang, Xin-Ting Sang, Hai-Tao Zhao

World J Gastroenterol. 2017 Aug 21; 23(31): 5787–5797. Published online 2017 Aug 21. doi: 10.3748/wjg.v23.i31.5787

PMCID:: PMC5569294

Abstract Article PDF–1.2M

Select item 534843215.

TTK is a favorable prognostic biomarker for triple-negative breast cancer survival

Qianqian Xu, Yali Xu, Bo Pan, Liangcai Wu, Xinyu Ren, Yidong Zhou, Feng Mao, Yan Lin, Jinghong Guan, Songjie Shen, Xiaohui Zhang, Changjun Wang, Ying Zhong, Liangrui Zhou, Zhiyong Liang, Haitao Zhao, Qiang Sun

Oncotarget. 2016 Dec 6; 7(49): 81815–81829. Published online 2016 Nov 9. doi: 10.18632/oncotarget.13245

PMCID:: PMC5348432

Abstract Article PDF–2.7M

Select item 502061516.

Utility of the dual-specificity protein kinase TTK as a therapeutic target for intrahepatic spread of liver cancer

Ruoyu Miao, Yan Wu, Haohai Zhang, Huandi Zhou, Xiaofeng Sun, Eva Csizmadia, Lian He, Yi Zhao, Chengyu Jiang, Rebecca A. Miksad, Tahereh Ghaziani, Simon C. Robson, Haitao Zhao

Sci Rep. 2016; 6: 33121. Published online 2016 Sep 13. doi: 10.1038/srep33121

PMCID:: PMC5020615

Abstract Article PDF–4.6M

Select item 497334317.

Mps1 kinase regulates tumor cell viability via its novel role in mitochondria

X Zhang, Y Ling, Y Guo, Y Bai, X Shi, F Gong, P Tan, Y Zhang, C Wei, X He, A Ramirez, X Liu, C Cao, H Zhong, Q Xu, R Z Ma

Cell Death Dis. 2016 Jul; 7(7): e2292. Published online 2016 Jul 7. doi: 10.1038/cddis.2016.193

PMCID:: PMC4973343

Abstract Article PDF–4.1M

Select item 494832318.

Modular elements of the TPR domain in the Mps1 N terminus differentially target Mps1 to the centrosome and kinetochore

Joseph R. Marquardt, Jennifer L. Perkins, Kyle J. Beuoy, Harold A. Fisk

Proc Natl Acad Sci U S A. 2016 Jul 12; 113(28): 7828–7833. Published online 2016 Jun 23. doi: 10.1073/pnas.1607421113

PMCID:: PMC4948323

Abstract Article PDF–1.5M

Select item 482309719.

Mps1 is SUMO-modified during the cell cycle

Agnese Restuccia, Feikun Yang, Changyan Chen, Lou Lu, Wei Dai

Oncotarget. 2016 Jan 19; 7(3): 3158–3170. Published online 2015 Dec 10. doi: 10.18632/oncotarget.6552

PMCID:: PMC4823097

Abstract Article PDF–5.7M

Select item 480804020.

Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition

Mohamed Jemaà, Gwenola Manic, Gwendaline Lledo, Delphine Lissa, Christelle Reynes, Nathalie Morin, Frédéric Chibon, Antonella Sistigu, Maria Castedo, Ilio Vitale, Guido Kroemer, Ariane Abrieu

Oncotarget. 2016 Jan 5; 7(1): 885–901. Published online 2015 Nov 30. doi: 10.18632/oncotarget.6432

PMCID:: PMC4808040

Abstract Article PDF–9.5M

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