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Select item 55803151.

Identification of predictive markers of the therapeutic effect of eribulin chemotherapy for locally advanced or metastatic breast cancer

Shinichiro Kashiwagi, Wakaba Fukushima, Yuka Asano, Wataru Goto, Koji Takada, Satoru Noda, Tsutomu Takashima, Naoyoshi Onoda, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira

BMC Cancer. 2017; 17: 604. Published online 2017 Aug 31. doi: 10.1186/s12885-017-3598-5

PMCID:: PMC5580315

Abstract Article PDF–1.7M

Select item 69689172.

TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth

Sander AL Palit, Daniel Vis, Suzan Stelloo, Cor Lieftink, Stefan Prekovic, Elise Bekers, Ingrid Hofland, Tonći Šuštić, Liesanne Wolters, Roderick Beijersbergen, Andries M Bergman, Balázs Győrffy, Lodewyk FA Wessels, Wilbert Zwart, Michiel S van der Heijden

eLife. 2019; 8: e47430. Published online 2019 Dec 19. doi: 10.7554/eLife.47430

PMCID:: PMC6968917

Abstract Article PDF–4.4M

Select item 36265673.

Adipose subtype–selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid-storage versus thermogenic gene programs

Claudio J. Villanueva, Laurent Vergnes, Jiexin Wang, Brian G. Drew, Cynthia Hong, Yiping Tu, Yan Hu, Xu Peng, Feng Xu, Enrique Saez, Kevin Wroblewski, Andrea L. Hevener, Karen Reue, Loren G. Fong, Stephen G. Young, Peter Tontonoz

Cell Metab. Author manuscript; available in PMC 2013 Sep 5.

Published in final edited form as: Cell Metab. 2013 Mar 5; 17(3): 423–435. doi: 10.1016/j.cmet.2013.01.016

PMCID:: PMC3626567

Abstract Article PDF–4.4M

Select item 53624364.

MicroRNA-744 promotes prostate cancer progression through aberrantly activating Wnt/β-catenin signaling

Han Guan, Chunhui Liu, Fang Fang, Yeqing Huang, Tao Tao, Zhixin Ling, Zonghao You, Xu Han, Shuqiu Chen, Bin Xu, Ming Chen

Oncotarget. 2017 Feb 28; 8(9): 14693–14707. Published online 2017 Jan 18. doi: 10.18632/oncotarget.14711

PMCID:: PMC5362436

Abstract Article PDF–11M

Select item 48622565.

Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development

Asaf Vivante, Marc-Jens Kleppa, Julian Schulz, Stefan Kohl, Amita Sharma, Jing Chen, Shirlee Shril, Daw-Yang Hwang, Anna-Carina Weiss, Michael M. Kaminski, Rachel Shukrun, Markus J. Kemper, Anja Lehnhardt, Rolf Beetz, Simone Sanna-Cherchi, Miguel Verbitsky, Ali G. Gharavi, Helen M. Stuart, Sally A. Feather, Judith A. Goodship, Timothy H.J. Goodship, Adrian S. Woolf, Sjirk J. Westra, Daniel P. Doody, Stuart B. Bauer, Richard S. Lee, Rosalyn M. Adam, Weining Lu, Heiko M. Reutter, Elijah O. Kehinde, Erika J. Mancini, Richard P. Lifton, Velibor Tasic, Soeren S. Lienkamp, Harald Jüppner, Andreas Kispert, Friedhelm Hildebrandt

Am J Hum Genet. 2015 Aug 6; 97(2): 291–301. Published online 2015 Jul 30. doi: 10.1016/j.ajhg.2015.07.001

PMCID:: PMC4862256

Abstract Article PDF–1.6M

Select item 60313336.

Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling

Victoria H. Ng, Brian I. Hang, Leah M. Sawyer, Leif R. Neitzel, Emily E. Crispi, Kristie L. Rose, Tessa M. Popay, Alison Zhong, Laura A. Lee, William P. Tansey, Stacey Huppert, Ethan Lee

J Cell Sci. 2018 May 15; 131(10): jcs210575. Published online 2018 May 22. doi: 10.1242/jcs.210575

PMCID:: PMC6031333

Abstract Article

Select item 100382017.

USP47 deubiquitylates Groucho/TLE to Promote Wnt-β-catenin Signaling

Sara Kassel, Alison J. Hanson, Hassina Benchabane, Kenyi Saito-Diaz, Carly R. Cabel, Lily Goldsmith, Muhammad Taha, Aksheta Kanuganti, Victoria H. Ng, George Xu, Fei Ye, Julia Picker, Fillip Port, Michael Boutros, Vivian L. Weiss, David J. Robbins, Curtis A. Thorne, Yashi Ahmed, Ethan Lee

Sci Signal. Author manuscript; available in PMC 2023 Aug 7.

Published in final edited form as: Sci Signal. 2023 Feb 7; 16(771): eabn8372. Published online 2023 Feb 7. doi: 10.1126/scisignal.abn8372

PMCID:: PMC10038201

Abstract Article PDF–1.6M

Select item 100896988.

TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis

Lindsey J. Anstine, Parth R. Majmudar, Amy Aponte, Salendra Singh, Ran Zhao, Kristen L. Weber-Bonk, Fadi W. Abdul-Karim, Mitchell Valentine, Darcie D. Seachrist, Katelyn E. Grennel-Nickelson, Leslie Cuellar-Vite, Gina M. Sizemore, Steven T. Sizemore, Bryan M. Webb, Cheryl L. Thompson, Ruth A. Keri

Cancer Res. Author manuscript; available in PMC 2023 Oct 4.

Published in final edited form as: Cancer Res. 2023 Apr 4; 83(7): 997–1015. doi: 10.1158/0008-5472.CAN-22-3133

PMCID:: PMC10089698

Abstract Article PDF–2.2M

Select item 32998369.

XIAP mono-ubiquitylates Groucho/TLE to promote canonical Wnt signaling

Alison J. Hanson, Heather A. Wallace, Tanner J. Freeman, R. Daniel Beauchamp, Laura A. Lee, Ethan Lee

Mol Cell. Author manuscript; available in PMC 2013 Mar 9.

Published in final edited form as: Mol Cell. 2012 Mar 9; 45(5): 619–628. Published online 2012 Feb 1. doi: 10.1016/j.molcel.2011.12.032

PMCID:: PMC3299836

Abstract Article PDF–3.4M

Select item 285235710.

Corepressors TLE1 and TLE3 Interact with HESX1 and PROP1

Luciani R. Carvalho, Michelle L. Brinkmeier, Frederic Castinetti, Buffy S. Ellsworth, Sally A. Camper

Mol Endocrinol. 2010 Apr; 24(4): 754–765. Published online 2010 Feb 24. doi: 10.1210/me.2008-0359

PMCID:: PMC2852357

Abstract Article

Select item 8678811.

The Winged-Helix Protein Brain Factor 1 Interacts with Groucho and Hes Proteins To Repress Transcription

Jing Yao, Eseng Lai, Stefano Stifani

Mol Cell Biol. 2001 Mar; 21(6): 1962–1972. doi: 10.1128/MCB.21.6.1962-1972.2001

PMCID:: PMC86788

Abstract Article PDF–1.1M

Select item 427012112.

Genome-Wide Association Study of Lung Function Phenotypes in a Founder Population

Tsung-Chieh Yao, Gaixin Du, Lide Han, Ying Sun, Donglei Hu, James J. Yang, Rasika Mathias, Lindsey A. Roth, Nicholas Rafaels, Emma E. Thompson, Dagan A. Loisel, Rebecca Anderson, Celeste Eng, Maitane Arruabarrena Orbegozo, Melody Young, James M. Klocksieben, Elizabeth Anderson, Kathleen Shanovich, Lucille A. Lester, L. Keoki Williams, Kathleen C. Barnes, Esteban G. Burchard, Dan L. Nicolae, Mark Abney, Carole Ober

J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: J Allergy Clin Immunol. 2014 Jan; 133(1): 248–55.e1-10. Published online 2013 Aug 6. doi: 10.1016/j.jaci.2013.06.018

PMCID:: PMC4270121

Abstract Article PDF–595K

Select item 316024513.

Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish

Hyunju Ro, Igor B Dawid

EMBO J. 2011 Jul 20; 30(14): 2894–2907. Published online 2011 Jun 10. doi: 10.1038/emboj.2011.184

PMCID:: PMC3160245

Abstract Article PDF–1.2M

Select item 441803014.

Heritability and genetic association analysis of cognition in the Diabetes Heart Study

Amanda J. Cox, Christina E. Hugenschmidt, Laura M. Raffield, Carl D. Langefeld, Barry I. Freedman, Jeff D. Williamson, Fang-Chi Hsu, Donald W. Bowden

Neurobiol Aging. Author manuscript; available in PMC 2015 May 4.

Published in final edited form as: Neurobiol Aging. 2014 Aug; 35(8): 1958.e3–1958.e12. Published online 2014 Mar 11. doi: 10.1016/j.neurobiolaging.2014.03.005

PMCID:: PMC4418030

Abstract Article PDF–1.5M

Select item 559224415.

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

Joshua E. Flack, Juliusz Mieszczanek, Nikola Novcic, Mariann Bienz

Mol Cell. 2017 Jul 20; 67(2): 181–193.e5. doi: 10.1016/j.molcel.2017.06.009

PMCID:: PMC5592244

Abstract Article

Select item 535222216.

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9

Laurens M van Tienen, Juliusz Mieszczanek, Marc Fiedler, Trevor J Rutherford, Mariann Bienz

eLife. 2017; 6: e20882. Published online 2017 Mar 15. doi: 10.7554/eLife.20882

Correction in:: eLife. 2017; 6: e27150.

PMCID:: PMC5352222

Abstract Article PDF–3.5M

Select item 846238017.

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1

Atsushi Yokoyama, Takumi Kouketsu, Yuri Otsubo, Erika Noro, Shun Sawatsubashi, Hiroki Shima, Ikuro Satoh, Sadafumi Kawamura, Takashi Suzuki, Kazuhiko Igarashi, Akira Sugawara

J Endocr Soc. 2021 Nov 1; 5(11): bvab150. Published online 2021 Sep 13. doi: 10.1210/jendso/bvab150

PMCID:: PMC8462380

Abstract Article PDF–892K

Select item 432309718.

AUTS2 confers gene activation to Polycomb group proteins in the CNS

Zhonghua Gao, Pedro Lee, James M. Stafford, Melanie von Schimmelmann, Anne Schaefer, Danny Reinberg

Nature. Author manuscript; available in PMC 2015 Jun 18.

Published in final edited form as: Nature. 2014 Dec 18; 516(7531): 349–354. doi: 10.1038/nature13921

PMCID:: PMC4323097

Abstract Article PDF–4.2M

Select item 554619819.

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Joanna K. Lempiäinen, Einari A. Niskanen, Kaisa-Mari Vuoti, Riikka E. Lampinen, Helka Göös, Markku Varjosalo, Jorma J. Palvimo

Mol Cell Proteomics. 2017 Aug; 16(8): 1462–1474. Published online 2017 Jun 13. doi: 10.1074/mcp.M117.067488

PMCID:: PMC5546198

Abstract Article PDF–3.1M

Select item 562926920.

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth

Bo Ram Kim, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Emily Van de Laar, Ming-Sound Tsao, Brian Raught, Nadeem Moghal

Mol Cell Proteomics. 2017 Oct; 16(10): 1864–1888. Published online 2017 Aug 9. doi: 10.1074/mcp.M116.064451

PMCID:: PMC5629269

Abstract Article PDF–5.6M

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PMC Links for Gene (Select 7090) (69)
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Mus musculus regulation of nuclear pre-mRNA domain containing 1B (Rprd1b), trans...
Mus musculus regulation of nuclear pre-mRNA domain containing 1B (Rprd1b), transcript variant 2, mRNA
gi|597955317|ref|NM_027434.3|

Nucleotide
PREDICTED: Homo sapiens TLE family member 3, transcriptional corepressor (TLE3),...
PREDICTED: Homo sapiens TLE family member 3, transcriptional corepressor (TLE3), transcript variant X12, mRNA
gi|2462545728|ref|XM_054378729.1|

Nucleotide

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