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Select item 88108691.

Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation

Minle Li, Xue Zhao, Hongmei Yong, Jian Xu, Pengfei Qu, Shuxi Qiao, Pingfu Hou, Zhongwei Li, Sufang Chu, Junnian Zheng, Jin Bai

Cell Death Dis. 2022 Feb; 13(2): 99. Published online 2022 Feb 2. doi: 10.1038/s41419-022-04575-5

PMCID:: PMC8810869

Abstract Article PDF–7.1M

Select item 66951142.

Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation

Donporn Riyapa, Darawan Rinchai, Veerachat Muangsombut, Chayanin Wuttinontananchai, Mohammed Toufiq, Damien Chaussabel, Manabu Ato, Jenefer M. Blackwell, Sunee Korbsrisate

PLoS One. 2019; 14(8): e0221016. Published online 2019 Aug 15. doi: 10.1371/journal.pone.0221016

PMCID:: PMC6695114

Abstract Article PDF–1.9M

Select item 49081493.

Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects

Lia Boyle, Mirjam M.C. Wamelink, Gajja S. Salomons, Birthe Roos, Ana Pop, Andrew Dauber, Vivian Hwa, Melissa Andrew, Jessica Douglas, Murray Feingold, Nancy Kramer, Sulagna Saitta, Kyle Retterer, Megan T. Cho, Amber Begtrup, Kristin G. Monaghan, Julia Wynn, Wendy K. Chung

Am J Hum Genet. 2016 Jun 2; 98(6): 1235–1242. Published online 2016 Jun 2. doi: 10.1016/j.ajhg.2016.03.030

PMCID:: PMC4908149

Abstract Article PDF–1.1M

Select item 47607874.

Transketolase counteracts oxidative stress to drive cancer development

Iris Ming-Jing Xu, Robin Kit-Ho Lai, Shu-Hai Lin, Aki Pui-Wah Tse, David Kung-Chun Chiu, Hui-Yu Koh, Cheuk-Ting Law, Chun-Ming Wong, Zongwei Cai, Carmen Chak-Lui Wong, Irene Oi-Lin Ng

Proc Natl Acad Sci U S A. 2016 Feb 9; 113(6): E725–E734. Published online 2016 Jan 25. doi: 10.1073/pnas.1508779113

PMCID:: PMC4760787

Abstract Article PDF–2.2M

Select item 108909325.

TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma

Longpo Geng, Mingming Zhu, Dongjun Luo, Huihui Chen, Binghua Li, Yuanxiang Lao, Hongda An, Yue Wu, Yunzheng Li, Anliang Xia, Yi Shi, Zhuting Tong, Shanshan Lu, Dengqiu Xu, Xu Wang, Wenjun Zhang, Beicheng Sun, Zhu Xu

Oncogene. 2024; 43(9): 682–692. Published online 2024 Jan 12. doi: 10.1038/s41388-023-02935-9

PMCID:: PMC10890932

Abstract Article PDF–3.8M

Select item 86303786.

Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway

Brian J. Shayota, Taraka R. Donti, Jing Xiao, Charul Gijavanekar, Adam D. Kennedy, Leroy Hubert, Lance Rodan, Christina Vanderpluym, Catherine Nowak, Hans T. Bjornsson, Rebecca Ganetzky, Gerard T. Berry, Kirk L. Pappan, V. Reid Sutton, Qin Sun, Sarah H. Elsea

Mol Genet Metab. Author manuscript; available in PMC 2021 Nov 30.

Published in final edited form as: Mol Genet Metab. 2020 Sep-Oct; 131(1-2): 147–154. Published online 2020 Aug 5. doi: 10.1016/j.ymgme.2020.07.013

PMCID:: PMC8630378

Abstract Article PDF–1.0M

Select item 75409677.

Genetic variants in TKT and DERA in the NADPH pathway predict melanoma survival

Ning Gu, Wei Dai, Hongliang Liu, Jie Ge, Sheng Luo, Eunyoung Cho, Christopher I. Amos, Jeffrey E. Lee, Xin Li, Hongmei Nan, Hua Yuan, Qingyi Wei

Eur J Cancer. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Eur J Cancer. 2020 Sep; 136: 84–94. Published online 2020 Jul 10. doi: 10.1016/j.ejca.2020.04.049

PMCID:: PMC7540967

Abstract Article PDF–782K

Select item 64420338.

Hepatitis B virus X protein–induced SH2 domain–containing 5 (SH2D5) expression promotes hepatoma cell growth via an SH2D5–transketolase interaction

Yongfa Zheng, Pingpo Ming, Chengliang Zhu, Yu Si, Shilei Xu, Aidong Chen, Jun Wang, Binghong Zhang

J Biol Chem. 2019 Mar 29; 294(13): 4815–4827. Published online 2019 Jan 18. doi: 10.1074/jbc.RA118.005739

PMCID:: PMC6442033

Abstract Article PDF–3.5M

Select item 41042319.

Akt Phosphorylation and Regulation of Transketolase Is a Nodal Point for Amino Acid Control of Purine Synthesis

Arindam Saha, Stephen Connelly, Jingjing Jiang, Shunhui Zhuang, Deron T. Amador, Tony Phan, Renate B. Pilz, Gerry R. Boss

Mol Cell. Author manuscript; available in PMC 2015 Jul 17.

Published in final edited form as: Mol Cell. 2014 Jul 17; 55(2): 264–276. Published online 2014 Jun 26. doi: 10.1016/j.molcel.2014.05.028

PMCID:: PMC4104231

Abstract Article PDF–2.3M

Select item 348515110.

A Δ38 Deletion Variant of Human Transketolase as a Model of Transketolase-Like Protein 1 Exhibits No Enzymatic Activity

Stefan Schneider, Stefan Lüdtke, Kathrin Schröder-Tittmann, Cindy Wechsler, Danilo Meyer, Kai Tittmann

PLoS One. 2012; 7(10): e48321. Published online 2012 Oct 31. doi: 10.1371/journal.pone.0048321

PMCID:: PMC3485151

Abstract Article PDF–740K

Select item 335208811.

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

Elizabeth Fullam, Florence Pojer, Terese Bergfors, T. Alwyn Jones, Stewart T. Cole

Open Biol. 2012 Jan; 2(1): 110026. doi: 10.1098/rsob.110026

PMCID:: PMC3352088

Abstract Article PDF–1.6M

Select item 295123012.

The Crystal Structure of Human Transketolase and New Insights into Its Mode of Action

Lars Mitschke, Christoph Parthier, Kathrin Schröder-Tittmann, Johannes Coy, Stefan Lüdtke, Kai Tittmann

J Biol Chem. 2010 Oct 8; 285(41): 31559–31570. Published online 2010 Jul 28. doi: 10.1074/jbc.M110.149955

PMCID:: PMC2951230

Abstract Article PDF–4.6M

Select item 696563613.

The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines

Minle Li, Xuping Zhang, Ying Lu, Sen Meng, Haoyu Quan, Pingfu Hou, Pan Tong, Dafei Chai, Xiaoge Gao, Junnian Zheng, Xuemei Tong, Jin Bai

Cell Death Dis. 2020 Jan; 11(1): 31. Published online 2020 Jan 16. doi: 10.1038/s41419-020-2225-6

PMCID:: PMC6965636

Abstract Article PDF–2.8M

Select item 720589714.

The MAP3K13-TRIM25-FBXW7α axis affects c-Myc protein stability and tumor development

Qiang Zhang, Xu Li, Kasa Cui, Cheng Liu, Mingzhi Wu, Edward V. Prochownik, Youjun Li

Cell Death Differ. 2020 Feb; 27(2): 420–433. Published online 2019 Jun 11. doi: 10.1038/s41418-019-0363-0

PMCID:: PMC7205897

Abstract Article PDF–3.9M

Select item 30219015.

A Method to Identify p62's UBA Domain Interacting Proteins

Julia W. Pridgeon, Thangiah Geetha, Marie W. Wooten

Biol Proced Online. 2003; 5: 228–237. Published online 2003 Dec 12. doi: 10.1251/bpo66

PMCID:: PMC302190

Abstract Article PDF–632K

Select item 893427416.

A FBXO7/EYA2-SCF^FBXW7 Axis Promotes AXL-mediated Maintenance of Mesenchymal and Immune Evasion Phenotypes of Cancer Cells

Jia Z. Shen, Zhixin Qiu, Qiulian Wu, Guoxin Zhang, Rebecca Harris, Dahui Sun, Juha Rantala, William D. Barshop, Linjie Zhao, Deguan Lv, Kwang-Ai Won, James Wohlschlegel, Olle Sangfelt, Heike Laman, Jeremy N. Rich, Charles Spruck

Mol Cell. Author manuscript; available in PMC 2023 Mar 17.

Published in final edited form as: Mol Cell. 2022 Mar 17; 82(6): 1123–1139.e8. Published online 2022 Feb 18. doi: 10.1016/j.molcel.2022.01.022

Retraction in:: Mol Cell. 2024 May 31

PMCID:: PMC8934274

Abstract Article

Select item 333819517.

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Nona Sotoodehnia, Aaron Isaacs, Paul I.W. de Bakker, Marcus Dörr, Christopher Newton-Cheh, Ilja M. Nolte, Pim van der Harst, Martina Müller, Mark Eijgelsheim, Alvaro Alonso, Andrew A. Hicks, Sandosh Padmanabhan, Caroline Hayward, Albert Vernon Smith, Ozren Polasek, Steven Giovannone, Jingyuan Fu, Jared W. Magnani, Kristin D. Marciante, Arne Pfeufer, Sina A. Gharib, Alexander Teumer, Man Li, Joshua C. Bis, Fernando Rivadeneira, Thor Aspelund, Anna Köttgen, Toby Johnson, Kenneth Rice, Mark P.S. Sie, Amanda Ying Wang, Norman Klopp, Christian Fuchsberger, Sarah H. Wild, Irene Mateo Leach, Karol Estrada, Uwe Völker, Alan F. Wright, Folkert W. Asselbergs, Jiaxiang Qu, Aravinda Chakravarti, Moritz F. Sinner, Jan A. Kors, Astrid Petersmann, Tamara B. Harris, Elsayed Z. Soliman, Patricia B. Munroe, Bruce M. Psaty, Ben A. Oostra, L. Adrienne Cupples, Siegfried Perz, Rudolf A. de Boer, André G. Uitterlinden, Henry Vözke, Timothy D. Spector, Fang-Yu Liu, Eric Boerwinkle, Anna F. Dominiczak, Jerome I. Rotter, Gé van Herpen, Daniel Levy, H.-Erich Wichmann, Wiek H. van Gilst, Jacqueline C.M. Witteman, Heyo K. Kroemer, W.H. Linda Kao, Susan R. Heckbert, Thomas Meitinger, Albert Hofman, Harry Campbell, Aaron R. Folsom, Dirk J. van Veldhuisen, Christine Schwienbacher, Christopher J. O’Donnell, Claudia Beu Volpato, Mark J. Caulfield, John M. Connell, Lenore Launer, Xiaowen Lu, Lude Franke, Rudolf S.N. Fehrmann, Gerard te Meerman, Harry J.M. Groen, Rinse K. Weersma, Leonard H. van den Berg, Cisca Wijmenga, Roel A. Ophoff, Gerjan Navis, Igor Rudan, Harold Snieder, James F. Wilson, Peter P. Pramstaller, David S. Siscovick, Thomas J. Wang, Vilmundur Gudnason, Cornelia M. van Duijn, Stephan B. Felix, Glenn I. Fishman, Yalda Jamshidi, Bruno H Ch Stricker, Nilesh J. Samani, Stefan Kääb, Dan E. Arking

Nat Genet. Author manuscript; available in PMC 2012 Apr 27.

Published in final edited form as: Nat Genet. 2010 Dec; 42(12): 1068–1076. Published online 2010 Nov 14. doi: 10.1038/ng.716

PMCID:: PMC3338195

Abstract Article PDF–951K

Select item 500801018.

The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence

Romina Burla, Mariateresa Carcuro, Mattia La Torre, Federica Fratini, Marco Crescenzi, Maria Rosaria D'Apice, Paola Spitalieri, Grazia Daniela Raffa, Letizia Astrologo, Giovanna Lattanzi, Enrico Cundari, Domenico Raimondo, Annamaria Biroccio, Maurizio Gatti, Isabella Saggio

Open Biol. 2016 Aug; 6(8): 160103. Published online 2016 Aug 10. doi: 10.1098/rsob.160103

PMCID:: PMC5008010

Abstract Article PDF–1.4M

Select item 476262219.

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein–Protein Interaction Data

Yuba Raj Pokharel, Jani Saarela, Agnieszka Szwajda, Christian Rupp, Anne Rokka, Shibendra Kumar Lal Karna, Kaisa Teittinen, Garry Corthals, Olli Kallioniemi, Krister Wennerberg, Tero Aittokallio, Jukka Westermarck

Mol Cell Proteomics. 2015 Dec; 14(12): 3274–3283. Published online 2015 Oct 23. doi: 10.1074/mcp.M115.050773

PMCID:: PMC4762622

Abstract Article PDF–1.4M

Select item 312311520.

The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle

Hans-Jörg Warnatz, Dominic Schmidt, Thomas Manke, Ilaria Piccini, Marc Sultan, Tatiana Borodina, Daniela Balzereit, Wasco Wruck, Alexey Soldatov, Martin Vingron, Hans Lehrach, Marie-Laure Yaspo

J Biol Chem. 2011 Jul 1; 286(26): 23521–23532. Published online 2011 May 9. doi: 10.1074/jbc.M111.220178

PMCID:: PMC3123115

Abstract Article PDF–2.2M

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