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Select item 101476151.

Transcription factor NKX2–1 drives serine and glycine synthesis addiction in cancer

Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Shauni L. Geeraerts, Tom Venken, Kalina Timcheva, David Nittner, Jelle Verbeeck, Jonathan Royaert, Marion Gijbels, Anne Uyttebroeck, Heidi Segers, Diether Lambrechts, Jan Cools, Kim De Keersmaecker, Kim R. Kampen

Br J Cancer. 2023 May 11; 128(10): 1862–1878. Published online 2023 Mar 17. doi: 10.1038/s41416-023-02216-y

PMCID:: PMC10147615

Abstract Article PDF–4.2M

Select item 99106492.

Exploring the values, preferences, and information needs of patients with NKX2-1-related disorders: A qualitative study protocol

Carmen Martín-Gómez, Juan Dario Ortigoza-Escobar, Laia Nou-Fontanet, Juan M. Molina-Linde, Anne-Catherine Bachoud-Lévi, Juliane Léger, Juan Antonio Blasco-Amaro, NKX2-1-Related Disorders Guideline Working Group

PLoS One. 2023; 18(2): e0281573. Published online 2023 Feb 9. doi: 10.1371/journal.pone.0281573

PMCID:: PMC9910649

Abstract Article PDF–508K

Select item 98950543.

Relationship between brain metastasis and thyroid transcription factor 1

Engin Kut, Serkan Menekşe

Sci Rep. 2023; 13: 1945. Published online 2023 Feb 2. doi: 10.1038/s41598-023-29236-1

PMCID:: PMC9895054

Abstract Article PDF–963K

Select item 89605664.

Altered pituitary morphology as a sign of benign hereditary chorea caused by TITF1/NKX2.1 mutations

Steffi Thust, Liana Veneziano, Michael H. Parkinson, Kailash P. Bhatia, Elide Mantuano, Cristina Gonzalez-Robles, Indran Davagnanam, Paola Giunti

Neurogenetics. 2022; 23(2): 91–102. Published online 2022 Jan 25. doi: 10.1007/s10048-021-00680-3

PMCID:: PMC8960566

Abstract Article PDF–1.1M

Select item 85752555.

NKX2-1 re-expression induces cell death through apoptosis and necrosis in dedifferentiated thyroid carcinoma cells

Yuko Ito, Fumihiko Furuya, Katsumi Taki, Hideaki Suzuki, Hiroki Shimura

PLoS One. 2021; 16(11): e0259558. Published online 2021 Nov 8. doi: 10.1371/journal.pone.0259558

PMCID:: PMC8575255

Abstract Article PDF–2.2M

Select item 82519156.

NKX2.1 run‐on mutation associated to familial brain–lung–thyroid syndrome

Elena Cavaliere, Anna Jolanda Gortan, Nadia Passon, Dora Fabbro, Dario Marin, Miryam Carecchio, Federica Baldan, Sara Carmela Credendino, Rosa Gallo, Paola Cogo, Giuseppe Damante, Gabriella De Vita

Clin Genet. 2021 Jul; 100(1): 114–116. Published online 2021 Mar 29. doi: 10.1111/cge.13961

PMCID:: PMC8251915

Abstract Article PDF–642K

Select item 81237447.

Deletion of conserved non‐coding sequences downstream from NKX2‐1: A novel disease‐causing mechanism for benign hereditary chorea

Jun Liao, Keith A. Coffman, Joseph Locker, Quasar S. Padiath, Bruce Nmezi, Robyn A. Filipink, Jie Hu, Malini Sathanoori, Suneeta Madan‐Khetarpal, Marianne McGuire, Allison Schreiber, Rocio Moran, Neil Friedman, Lori Hoffner, Aleksandar Rajkovic, Svetlana A. Yatsenko, Urvashi Surti

Mol Genet Genomic Med. 2021 Apr; 9(4): e1647. Published online 2021 Mar 5. doi: 10.1002/mgg3.1647

PMCID:: PMC8123744

Abstract Article PDF–1.0M

Select item 81152948.

CRISPRi-mediated functional analysis of NKX2-1-binding sites in the lung

William D. Stuart, Iris M. Fink-Baldauf, Koichi Tomoshige, Minzhe Guo, Yutaka Maeda

Commun Biol. 2021; 4: 568. Published online 2021 May 12. doi: 10.1038/s42003-021-02083-4

PMCID:: PMC8115294

Abstract Article PDF–3.4M

Select item 69983949.

Comparative analysis of TTF‐1 binding DNA regions in small‐cell lung cancer and non‐small‐cell lung cancer

Satoshi Hokari, Yusuke Tamura, Atsushi Kaneda, Akihiro Katsura, Masato Morikawa, Fumihiko Murai, Shogo Ehata, Shuichi Tsutsumi, Yuichi Ishikawa, Hiroyuki Aburatani, Toshiaki Kikuchi, Kohei Miyazono, Daizo Koinuma

Mol Oncol. 2020 Feb; 14(2): 277–293. Published online 2019 Dec 15. doi: 10.1002/1878-0261.12608

PMCID:: PMC6998394

Abstract Article PDF–4.1M

Select item 654160410.

Mechanistic Study of TTF-1 Modulation of Cellular Sensitivity to Cisplatin

Cody A. Phelps, Laura Lindsey-Boltz, Aziz Sancar, David Mu

Sci Rep. 2019; 9: 7990. Published online 2019 May 29. doi: 10.1038/s41598-019-44549-w

PMCID:: PMC6541604

Abstract Article PDF–4.3M

Select item 641025111.

Correlation of Thyroid Transcription Factor-1 Expression with EGFR Mutations in Non-Small-Cell Lung Cancer: A Meta-Analysis

Hyeong Su Kim, Jung Han Kim, Boram Han, Dae Ro Choi

Medicina (Kaunas) 2019 Feb; 55(2): 41. Published online 2019 Feb 7. doi: 10.3390/medicina55020041

PMCID:: PMC6410251

Abstract Article PDF–3.0M

Select item 601513212.

甲状腺转录因子在宣威肺腺癌中的表达及临床意义

俎云芬, 王熙才, 刘馨, 陈艳, 李承文, 尚学琴, 谢余澄, 赵虹园, 王继营

Zhongguo Fei Ai Za Zhi. 2013 Mar 20; 16(3): 131–137. Chinese. doi: 10.3779/j.issn.1009-3419.2013.03.03

PMCID:: PMC6015132

Abstract Article PDF–1.2M

Select item 600383913.

Thyroid transcription factor 1 enhances cellular statin sensitivity via perturbing cholesterol metabolism

Shao-Chiang Lai, Cody A. Phelps, Aleena M. Short, Sucharita M. Dutta, David Mu

Oncogene. Author manuscript; available in PMC 2018 Sep 19.

Published in final edited form as: Oncogene. 2018 Jun; 37(24): 3290–3300. Published online 2018 Mar 19. doi: 10.1038/s41388-018-0174-7

PMCID:: PMC6003839

Abstract Article PDF–970K

Select item 566015914.

The role of Thyroid Transcription Factor-1 and Tumor differentiation in Resected Lung Adenocarcinoma

Tsai-Wang Huang, Ke- Feng Lin, Chien-Hsing Lee, Hung Chang, Shih-Chun Lee, Yi-Shing Shieh

Sci Rep. 2017; 7: 14222. Published online 2017 Oct 27. doi: 10.1038/s41598-017-14651-y

PMCID:: PMC5660159

Abstract Article PDF–1.8M

Select item 558151515.

Inactivating mutations and hypermethylation of the NKX2‐1/TTF‐1 gene in non‐terminal respiratory unit‐type lung adenocarcinomas

Daisuke Matsubara, Manabu Soda, Taichiro Yoshimoto, Yusuke Amano, Yuji Sakuma, Azusa Yamato, Toshihide Ueno, Shinya Kojima, Tomoki Shibano, Yasuyuki Hosono, Masahito Kawazu, Yoshihiro Yamashita, Shunsuke Endo, Koichi Hagiwara, Masashi Fukayama, Takashi Takahashi, Hiroyuki Mano, Toshiro Niki

Cancer Sci. 2017 Sep; 108(9): 1888–1896. Published online 2017 Jul 29. doi: 10.1111/cas.13313