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Select item 86910181.

Low thyroid hormone receptor alpha-2 (THRα-2) tumor expression is associated with unfavorable tumor characteristics and high breast cancer mortality

Malte Sandsveden, Signe Borgquist, Ann H. Rosendahl, Jonas Manjer

Breast Cancer Res. 2021; 23: 117. Published online 2021 Dec 20. doi: 10.1186/s13058-021-01496-7

PMCID:: PMC8691018

Abstract Article PDF–1.4M

Select item 82903132.

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi

Emery Di Cicco, Carla Moran, W. Edward Visser, Annarita Nappi, Erik Schoenmakers, Pamela Todd, Greta Lyons, Mehul Dattani, Raffaele Ambrosio, Silvia Parisi, Domenico Salvatore, Krishna Chatterjee, Monica Dentice

Thyroid. July 2021; 31(7): 1114–1126. Published online 2021 Jul 8. doi: 10.1089/thy.2020.0391

PMCID:: PMC8290313

Abstract Article PDF–2.1M

Select item 81591253.

A New Mechanism in THRA Resistance: The First Disease-Associated Variant Leading to an Increased Inhibitory Function of THRA2

Sarah Paisdzior, Ellen Knierim, Gunnar Kleinau, Heike Biebermann, Heiko Krude, Rachel Straussberg, Markus Schuelke

Int J Mol Sci. 2021 May; 22(10): 5338. Published online 2021 May 19. doi: 10.3390/ijms22105338

PMCID:: PMC8159125

Abstract Article PDF–1.1M

Select item 80420044.

Thyroid hormone receptor α1 acts as a new squamous cell lung cancer diagnostic marker and poor prognosis predictor

Fatma El Zahraa A. Mohamed, Ali Omar Abdelaziz, Ahmed Hussein Kasem, Tarek Ellethy, Mariana F. Gayyed

Sci Rep. 2021; 11: 7944. Published online 2021 Apr 12. doi: 10.1038/s41598-021-86754-6

PMCID:: PMC8042004

Abstract Article PDF–1.6M

Select item 68426155.

Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development

Teresa G. Krieger, Carla M. Moran, Alberto Frangini, W. Edward Visser, Erik Schoenmakers, Francesco Muntoni, Chris A. Clark, David Gadian, Wui K. Chong, Adam Kuczynski, Mehul Dattani, Greta Lyons, Alexandra Efthymiadou, Faraneh Vargha-Khadem, Benjamin D. Simons, Krishna Chatterjee, Frederick J. Livesey

Proc Natl Acad Sci U S A. 2019 Nov 5; 116(45): 22754–22763. Published online 2019 Oct 18. doi: 10.1073/pnas.1908762116

Correction in:: Proc Natl Acad Sci U S A. 2020 Mar 31; 117(13): 7537–7538.

PMCID:: PMC6842615

Abstract Article PDF–2.5M

Select item 59899266.

Resistance to Thyroid Hormone due to a mutation in thyroid hormone receptor a1 and the a2 variant protein

Carla Moran, Maura Agostini, W. Edward Visser, Erik Schoenmakers, Nadia Schoenmakers, Amaka C. Offiah, Ken Poole, Odelia Rajanayagam, Greta Lyons, David Halsall, Mark Gurnell, Dionisios Chrysis, Alexandra Efthymiadou, Charles Buchanan, Simon Aylwin, Krishna Chatterjee

Lancet Diabetes Endocrinol. Author manuscript; available in PMC 2018 Jun 6.

Published in final edited form as: Lancet Diabetes Endocrinol. 2014 Aug; 2(8): 619–626. Published online 2014 Jun 23. doi: 10.1016/S2213-8587(14)70111-1

PMCID:: PMC5989926

Abstract Article PDF–1.3M

Select item 54149257.

Identification of a New Hormone-Binding Site on the Surface of Thyroid Hormone Receptor

P.C.T. Souza, A.C. Puhl, L. Martínez, R. Aparício, A.S. Nascimento, A.C.M. Figueira, P. Nguyen, P. Webb, M.S Skaf, I. Polikarpov

Mol Endocrinol. 2014 Apr; 28(4): 534–545. Published online 2014 Feb 19. doi: 10.1210/me.2013-1359

PMCID:: PMC5414925

Abstract Article

Select item 46341118.

Recruitment of the Oncoprotein v-ErbA to Aggresomes

Cornelius Bondzi, Abigail M. Brunner, Michelle R. Munyikwa, Crystal D. Connor, Alicia N. Simmons, Stephanie L. Stephens, Patricia A. Belt, Vincent R. Roggero, Manohara S. Mavinakere, Shantá D. Hinton, Lizabeth A. Allison

Mol Cell Endocrinol. Author manuscript; available in PMC 2015 Nov 5.

Published in final edited form as: Mol Cell Endocrinol. 2011 Jan 30; 332(0): 196–212. Published online 2010 Nov 12. doi: 10.1016/j.mce.2010.10.012

PMCID:: PMC4634111

Abstract Article PDF–1.7M

Select item 28084549.

A conserved lysine in the thyroid hormone receptor (TR)-α1 DNA binding domain, mutated in hepatocellular carcinoma, serves as a sensor for transcriptional regulation

Ivan H. Chan, Martin L. Privalsky

Mol Cancer Res. Author manuscript; available in PMC 2011 Jan 6.

Published in final edited form as: Mol Cancer Res. 2010 Jan; 8(1): 15–23. Published online 2010 Jan 6. doi: 10.1158/1541-7786.MCR-09-0425

PMCID:: PMC2808454

Abstract Article PDF–898K

Select item 30650510.

Nucleotide sequence of cDNA encoding a novel human thyroid hormone receptor.

M Pfahl, D Benbrook

Nucleic Acids Res. 1987 Nov 25; 15(22): 9613. doi: 10.1093/nar/15.22.9613

PMCID:: PMC306505

Summary Page Browse PDF–142K

Select item 28008311.

Characterization of a thyroid hormone receptor expressed in human kidney and other tissues.

A Nakai, S Seino, A Sakurai, I Szilak, G I Bell, L J DeGroot

Proc Natl Acad Sci U S A. 1988 Apr; 85(8): 2781–2785. doi: 10.1073/pnas.85.8.2781

PMCID:: PMC280083

Summary Page Browse PDF–1.0M

Select item 1103964212.

Spatiotemporal expression of thyroid hormone transporter MCT8 and THRA mRNA in human cerebral organoids recapitulating first trimester cortex development

Adina Sophie Graffunder, Audrey Amber Julie Bresser, Valeria Fernandez Vallone, Matthias Megges, Harald Stachelscheid, Peter Kühnen, Robert Opitz

Sci Rep. 2024; 14: 9355. Published online 2024 Apr 23. doi: 10.1038/s41598-024-59533-2

PMCID:: PMC11039642

Abstract Article PDF–4.5M

Select item 971811813.

Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions

Maria Virginia Giolito, Théo La Rosa, Diana Farhat, Serguei Bodoirat, Gabriela D. A. Guardia, Claire Domon‐Dell, Pedro A. F. Galante, Jean‐Noel Freund, Michelina Plateroti

Mol Oncol. 2022 Dec; 16(22): 3975–3993. Published online 2022 Oct 10. doi: 10.1002/1878-0261.13298

PMCID:: PMC9718118

Abstract Article PDF–2.2M

Select item 794727314.

Life Without Thyroid Hormone Receptor

Yun-Bo Shi

Endocrinology. 2021 Apr; 162(4): bqab028. Published online 2021 Feb 9. doi: 10.1210/endocr/bqab028

PMCID:: PMC7947273

Abstract Article

Select item 738910915.

先天性甲状腺功能减退症患儿GNAS和THRA基因突变分析

陈晓宇, 刘勇, 刘建华, 秦晓松

Zhongguo Dang Dai Er Ke Za Zhi. 2019 Jul 25; 21(7): 680–684. Chinese. doi: 10.7499/j.issn.1008-8830.2019.07.012

PMCID:: PMC7389109

Abstract Article PDF–1.2M

Select item 679538716.

Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes

Valentina Benedetti, Angelo Michele Lavecchia, Monica Locatelli, Valerio Brizi, Daniela Corna, Marta Todeschini, Rubina Novelli, Ariela Benigni, Carlamaria Zoja, Giuseppe Remuzzi, Christodoulos Xinaris

JCI Insight. 2019 Sep 19; 4(18): e130249. Published online 2019 Sep 19. doi: 10.1172/jci.insight.130249

PMCID:: PMC6795387

Abstract Article PDF–44M

Select item 506142217.

Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells

Aleksandra Cvoro, Aleksandar Bajic, Aijun Zhang, Marisa Simon, Igor Golic, Douglas H. Sieglaff, Mirjana Maletic-Savatic, Aleksandra Korac, Paul Webb

PLoS One. 2016; 11(10): e0164407. Published online 2016 Oct 12. doi: 10.1371/journal.pone.0164407

PMCID:: PMC5061422

Abstract Article PDF–4.0M

Select item 413857818.

Thyroid Hormone Receptor α Mutation Causes a Severe and Thyroxine-Resistant Skeletal Dysplasia in Female Mice

J. H. Duncan Bassett, Alan Boyde, Tomas Zikmund, Holly Evans, Peter I. Croucher, Xuguang Zhu, Jeong Won Park, Sheue-yann Cheng, Graham R. Williams

Endocrinology. 2014 Sep; 155(9): 3699–3712. Published online 2014 Jun 10. doi: 10.1210/en.2013-2156

PMCID:: PMC4138578

Abstract Article

Select item 400477819.

The Ability of Thyroid Hormone Receptors to Sense T₄ as an Agonist Depends on Receptor Isoform and on Cellular Cofactors

Amy Schroeder, Robyn Jimenez, Briana Young, Martin L. Privalsky

Mol Endocrinol. 2014 May; 28(5): 745–757. Published online 2014 Mar 27. doi: 10.1210/me.2013-1335

PMCID:: PMC4004778

Abstract Article

Select item 353677720.

Gene Specific Actions of Thyroid Hormone Receptor Subtypes

Jean Z. Lin, Douglas H. Sieglaff, Chaoshen Yuan, Jing Su, AnithaChristy S. Arumanayagam, Sharareh Firouzbakht, Jaime J. Cantu Pompa, Frances Denoto Reynolds, Xiabo Zhou, Aleksandra Cvoro, Paul Webb

PLoS One. 2013; 8(1): e52407. Published online 2013 Jan 3. doi: 10.1371/journal.pone.0052407

PMCID:: PMC3536777

Abstract Article PDF–1.3M

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