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Items: 1 to 20 of 68

1.
An integrated pan‐cancer analysis of TFAP4 aberrations and the potential clinical implications for cancer immunity
Jian‐Nan Liu, Xiang‐Shuo Kong, Ping Sun, Rui Wang, Wang Li, Qi‐Feng Chen
J Cell Mol Med. 2021 Feb; 25(4): 2082–2097. Published online 2020 Dec 29. doi: 10.1111/jcmm.16147
PMCID:
PMC7882993
AbstractArticlePDF–3.6M
2.
Transcription factor AP‐4 (TFAP4)‐upstream ORF coding 66 aa inhibits the malignant behaviors of glioma cells by suppressing the TFAP4/long noncoding RNA 00520/microRNA‐520f‐3p feedback loop
Yipeng Wang, Chunqing Yang, Xiaobai Liu, Jian Zheng, Fangfang Zhang, Di Wang, Yixue Xue, Xiaozhi Li, Shuyuan Shen, Lianqi Shao, Yang Yang, Libo Liu, Jun Ma, Yunhui Liu
Cancer Sci. 2020 Mar; 111(3): 891–906. Published online 2020 Feb 11. doi: 10.1111/cas.14308
PMCID:
PMC7060482
AbstractArticlePDF–4.2M
3.
TFAP4 Promotes Hepatocellular Carcinoma Invasion and Metastasis via Activating the PI3K/AKT Signaling Pathway
Tao Huang, Qi-Feng Chen, Bo-Yang Chang, Lu-Jun Shen, Wang Li, Pei-Hong Wu, Wei-Jun Fan
Dis Markers. 2019; 2019: 7129214. Published online 2019 Jun 10. doi: 10.1155/2019/7129214
PMCID:
PMC6590577
AbstractArticlePDF–6.8M
4.
AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer
Rene Jackstadt, Simone Röh, Jens Neumann, Peter Jung, Reinhard Hoffmann, David Horst, Christian Berens, Georg W. Bornkamm, Thomas Kirchner, Antje Menssen, Heiko Hermeking
J Exp Med. 2013 Jul 1; 210(7): 1331–1350. doi: 10.1084/jem.20120812
PMCID:
PMC3698521
AbstractArticlePDF–3.9M
5.
Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells
Xinghua Liu, Bo Zhang, Yan Guo, Qi Liang, Changyao Wu, Lei Wu, Kaixiong Tao, Guobin Wang, Jianying Chen
PLoS One. 2012; 7(5): e37096. Published online 2012 May 16. doi: 10.1371/journal.pone.0037096
PMCID:
PMC3353913
AbstractArticlePDF–2.8M
6.
Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis
Margaret A. Potts, Shinsuke Mizutani, Alexandra L. Garnham, Connie S. N. Li Wai Suen, Andrew J. Kueh, Lin Tai, Martin Pal, Andreas Strasser, Marco J. Herold
Cell Death Differ. 2023 Jun; 30(6): 1447–1456. Published online 2023 Mar 9. doi: 10.1038/s41418-023-01145-w
PMCID:
PMC10244435
AbstractArticlePDF–3.2M
7.
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer
Kimberly R. Hagel, Rand Arafeh, Sydney Gang, Taylor E. Arnoff, Rebecca C. Larson, John G. Doench, Nathan D. Mathewson, Kai W. Wucherpfennig, Marcela V. Maus, William C. Hahn
Cancer Res. 2023 Feb 15; 83(4): 613–625. Published online 2022 Dec 22. doi: 10.1158/0008-5472.CAN-22-2245
PMCID:
PMC9929516
AbstractArticlePDF–2.5M
8.
Inhibitory effect of CC chemokine ligand 23 (CCL23)/ transcription factor activating enhancer binding protein 4 (TFAP4) on cell proliferation, invasion and angiogenesis in hepatocellular carcinoma
Weiwei Wang, Jianjun Wu, Xulei Dai, Kun Cheng
Bioengineered. 2022; 13(1): 1626–1636. Published online 2022 Jan 8. doi: 10.1080/21655979.2021.2021125
PMCID:
PMC8805957
AbstractArticlePDF–3.5M
9.
Upregulating microRNA-373-3p promotes apoptosis and inhibits metastasis of hepatocellular carcinoma cells
Hongbin Li, Nan Wang, Yuntian Xu, Xiao Chang, Jing Ke, Jun Yin
Bioengineered. 2022; 13(1): 1304–1319. Published online 2022 Jan 5. doi: 10.1080/21655979.2021.2014616
PMCID:
PMC8805941
AbstractArticlePDF–4.2M
10.
The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression
Rachael Thomas, Davide Trapani, Lily Goodyer-Sait, Marketa Tomkova, Ceres Fernandez-Rozadilla, Nora Sahnane, Connor Woolley, Hayley Davis, Laura Chegwidden, Skirmantas Kriaucionis, Timothy Maughan, Simon Leedham, Claire Palles, Daniela Furlan, Ian Tomlinson, Annabelle Lewis
Sci Rep. 2019; 9: 13463. Published online 2019 Sep 17. doi: 10.1038/s41598-019-49952-x
PMCID:
PMC6748923
AbstractArticlePDF–2.7M
11.
Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma
Shuobo Boboila, Gonzalo Lopez, Jiyang Yu, Debarshi Banerjee, Angela Kadenhe-Chiweshe, Eileen P. Connolly, Jessica J. Kandel, Presha Rajbhandari, Jose M. Silva, Andrea Califano, Darrell J. Yamashiro
Oncogene. 2018; 37(40): 5451–5465. Published online 2018 Jun 7. doi: 10.1038/s41388-018-0326-9
PMCID:
PMC6172192
AbstractArticlePDF–4.9M
12.
AP4 modulated by the PI3K/AKT pathway promotes prostate cancer proliferation and metastasis of prostate cancer via upregulating L-plastin
Changhao Chen, Qingqing Cai, Wang He, Thomas B Lam, Jianxun Lin, Yue Zhao, Xu Chen, Peng Gu, Hao Huang, Miaoxin Xue, Hao Liu, Feng Su, Jian Huang, Jianping Zheng, Tianxin Lin
Cell Death Dis. 2017 Oct; 8(10): e3060. Published online 2017 Oct 5. doi: 10.1038/cddis.2017.437
PMCID:
PMC5680569
AbstractArticlePDF–7.1M
13.
USP22 drives colorectal cancer invasion and metastasis via epithelial-mesenchymal transition by activating AP4
Yongmin Li, Yanmei Yang, Jingwen Li, He Liu, Fuxun Chen, Bingyang Li, Binbin Cui, Yanlong Liu
Oncotarget. 2017 May 16; 8(20): 32683–32695. Published online 2017 Mar 6. doi: 10.18632/oncotarget.15950
PMCID:
PMC5464819
AbstractArticlePDF–3.5M
14.
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
Chengyuan Xue, Denise M.T. Yu, Samuele Gherardi, Jessica Koach, Giorgio Milazzo, Laura Gamble, Bing Liu, Emanuele Valli, Amanda J. Russell, Wendy B. London, Tao Liu, Belamy B. Cheung, Glenn M. Marshall, Giovanni Perini, Michelle Haber, Murray D. Norris
Oncotarget. 2016 Aug 23; 7(34): 54937–54951. Published online 2016 Jul 19. doi: 10.18632/oncotarget.10709
PMCID:
PMC5342392
AbstractArticlePDF–9.9M
15.
AP4 is required for mitogen- and c-MYC-induced cell cycle progression
Rene Jackstadt, Heiko Hermeking
Oncotarget. 2014 Sep; 5(17): 7316–7327. Published online 2014 Aug 19. doi: 10.18632/oncotarget.2348
PMCID:
PMC4202125
AbstractArticlePDF–4.3M
16.
TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling
Zhenlin Hou, Kaixuan Guo, Xuling Sun, Fuqing Hu, Qianzhi Chen, Xuelai Luo, Guihua Wang, Junbo Hu, Li Sun
Mol Cancer. 2018; 17: 172. Published online 2018 Dec 12. doi: 10.1186/s12943-018-0922-x
PMCID:
PMC6291992
AbstractArticlePDF–3.1M
17.
Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma
Junwei Song, Chan Xie, Lili Jiang, Geyan Wu, Jinrong Zhu, Shuxia Zhang, Miaoling Tang, Libing Song, Jun Li
Theranostics. 2018; 8(13): 3571–3583. Published online 2018 Jun 7. doi: 10.7150/thno.25194
PMCID:
PMC6037031
AbstractArticlePDF–2.1M
18.
Transcription factor AP-4 is a ligand for immunoglobulin-kappa promoter E-box elements.
A Aranburu, R Carlsson, C Persson, T Leanderson
Biochem J. 2001 Mar 1; 354(Pt 2): 431–438. doi: 10.1042/0264-6021:3540431
PMCID:
PMC1221672
SummaryPDF–248K
19.
Unexpected suppression of tumorigenesis by c-MYC via TFAP4-dependent restriction of stemness in B lymphocytes
Elena Tonc, Yoshiko Takeuchi, Chun Chou, Yu Xia, Melanie Holmgren, Chika Fujii, Saravanan Raju, Gue Su Chang, Masahiro Iwamoto, Takeshi Egawa
Blood. 2021 Dec 16; 138(24): 2526–2538. doi: 10.1182/blood.2021011711
PMCID:
PMC8678995
AbstractArticle
20.
Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells
Stephanie Jaeckel, Markus Kaller, Rene Jackstadt, Ursula Götz, Susanna Müller, Sophie Boos, David Horst, Peter Jung, Heiko Hermeking
Nat Commun. 2018; 9: 3573. Published online 2018 Sep 3. doi: 10.1038/s41467-018-06001-x
PMCID:
PMC6120921
AbstractArticlePDF–3.7M

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