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Select item 111588381.

Up‐regulated expression of ADAM17 in gastrointestinal stromal tumors: coexpression with EGFR and EGFR ligands

Motomichi Nakagawa, Kazuki Nabeshima, Shigeyuki Asano, Makoto Hamasaki, Noriko Uesugi, Hiroki Tani, Yuichi Yamashita, Hiroshi Iwasaki

Cancer Sci. 2009 Apr; 100(4): 654–662. Published online 2009 Mar 1. doi: 10.1111/j.1349-7006.2009.01089.x

PMCID:: PMC11158838

Abstract Article PDF–2.1M

Select item 108981232.

Tumor-derived exosomal ADAM17 promotes pre-metastatic niche formation by enhancing vascular permeability in colorectal cancer

Keyu Li, Wenhua Xue, Zhihua Lu, Suo Wang, Jiayao Zheng, Kuangyi Lu, Ming Li, Yang Zong, Feng Xu, Jiamin Dai, Yang Yang, Jinbing Sun

J Exp Clin Cancer Res. 2024; 43: 59. Published online 2024 Feb 27. doi: 10.1186/s13046-024-02991-3

PMCID:: PMC10898123

Abstract Article PDF–16M

Select item 108609473.

Expression of ADAM17 and its clinical value for patients with pernicious placenta previa: A retrospective study of 148 PPP patients underwent cesarean section

Xiutao Huang, Xingxing Wang, Xiang Xiao, Jin Li, Hang Yuan, Li Hou

Medicine (Baltimore) 2024 Feb 9; 103(6): e32848. Published online 2024 Feb 9. doi: 10.1097/MD.0000000000032848

PMCID:: PMC10860947

Abstract Article PDF–532K

Select item 107074064.

Predictive Roles of ADAM17 in Patient Survival and Immune Cell Infiltration in Hepatocellular Carcinoma

Tianlong Ding, Yang Yu, Lei Gao, Lin Xiang, Bo Xu, Baohong Gu, Hao Chen

Int J Mol Sci. 2023 Dec; 24(23): 17069. Published online 2023 Dec 2. doi: 10.3390/ijms242317069

PMCID:: PMC10707406

Abstract Article PDF–22M

Select item 106474615.

Genetic Predisposition to Elevated Levels of Circulating ADAM17 Is Associated with the Risk of Severe COVID-19

Mengyu Pan, Isabel Goncalves, Andreas Edsfeldt, Jiangming Sun, Per Swärd

Int J Mol Sci. 2023 Nov; 24(21): 15879. Published online 2023 Nov 1. doi: 10.3390/ijms242115879

PMCID:: PMC10647461

Abstract Article PDF–763K

Select item 104383786.

ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways

Anzelika Rubina, Mihil Patel, Katie Nightingale, Martin Potts, Ceri A. Fielding, Simon Kollnberger, Betty Lau, Kristin Ladell, Kelly L. Miners, Jenna Nichols, Luis Nobre, Dawn Roberts, Terrence M. Trinca, Jason P. Twohig, Virginia-Maria Vlahava, Andrew J. Davison, David A. Price, Peter Tomasec, Gavin W. G. Wilkinson, Michael P. Weekes, Richard J. Stanton, Eddie C. Y. Wang

Proc Natl Acad Sci U S A. 2023 Aug 15; 120(33): e2303155120. Published online 2023 Aug 10. doi: 10.1073/pnas.2303155120

PMCID:: PMC10438378

Abstract Article PDF–1.5M

Select item 104171497.

Ectodomain Shedding by ADAM17 Increases the Release of Soluble CD40 from Human Endothelial Cells under Pro-Inflammatory Conditions

Anton Klersy, Sören Meyer, Florian Leuschner, Thorsten Kessler, Markus Hecker, Andreas H. Wagner

Cells. 2023 Aug; 12(15): 1926. Published online 2023 Jul 25. doi: 10.3390/cells12151926

PMCID:: PMC10417149

Abstract Article PDF–2.0M

Select item 97159638.

Immunomodulatory role of metalloproteinase ADAM17 in tumor development

Kai Wang, Zixue Xuan, Xiaoyan Liu, Meiling Zheng, Chao Yang, Haiyong Wang

Front Immunol. 2022; 13: 1059376. Published online 2022 Nov 17. doi: 10.3389/fimmu.2022.1059376

PMCID:: PMC9715963

Abstract Article PDF–3.0M

Select item 96755559.

ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion

Sebastian P. Gnosa, Laia Puig Blasco, Krzysztof B. Piotrowski, Marie L. Freiberg, Simonas Savickas, Daniel H. Madsen, Ulrich auf dem Keller, Pauliina Kronqvist, Marie Kveiborg

JCI Insight. 2022 Sep 22; 7(18): e155296. Published online 2022 Sep 22. doi: 10.1172/jci.insight.155296

PMCID:: PMC9675555

Abstract Article PDF–7.2M

Select item 951211510.

ADAM17 cleaves the insulin receptor ectodomain on endothelial cells and causes vascular insulin resistance

Thaysa Ghiarone, Jorge A. Castorena-Gonzalez, Christopher A. Foote, Francisco I. Ramirez-Perez, Larissa Ferreira-Santos, Francisco J. Cabral-Amador, Roger de la Torre, Rama R. Ganga, Andrew A. Wheeler, Camila Manrique-Acevedo, Jaume Padilla, Luis A. Martinez-Lemus

Am J Physiol Heart Circ Physiol. 2022 Oct 1; 323(4): H688–H701. Published online 2022 Aug 26. doi: 10.1152/ajpheart.00039.2022

PMCID:: PMC9512115

Abstract Article

Select item 933176311.

Pseudomonas aeruginosa Alters Critical Lung Epithelial Cell Functions through Activation of ADAM17

Ahmad Aljohmani, Noah Niklas Andres, Daniela Yildiz

Cells. 2022 Aug; 11(15): 2303. Published online 2022 Jul 26. doi: 10.3390/cells11152303

PMCID:: PMC9331763

Abstract Article PDF–3.1M

Select item 922644412.

An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model

Jodi F. Hedges, Deann T. Snyder, Amanda Robison, Heather M. Grifka-Walk, Karlin Blackwell, Kelly Shepardson, Douglas Kominsky, Agnieszka Rynda-Apple, Bruce Walcheck, Mark A. Jutila

Front Immunol. 2022; 13: 918881. Published online 2022 Jun 10. doi: 10.3389/fimmu.2022.918881

PMCID:: PMC9226444

Abstract Article PDF–4.3M

Select item 920386013.

The Correlation Between Immune Invasion and SARS-COV-2 Entry Protein ADAM17 in Cancer Patients by Bioinformatic Analysis

Kai Wang, Haoyue Deng, Binghui Song, Jiayue He, Shuguang Liu, Jiewen Fu, Lianmei Zhang, Dabing Li, Kyathegowdanadoddi Srinivasa Balaji, Zhiqiang Mei, Jingliang Cheng, Junjiang Fu

Front Immunol. 2022; 13: 923516. Published online 2022 Jun 3. doi: 10.3389/fimmu.2022.923516

PMCID:: PMC9203860

Abstract Article PDF–15M

Select item 883578714.

In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators

Marian Bienstein, Dmitriy Minond, Ulrich Schwaneberg, Mehdi D. Davari, Daniela Yildiz

Int J Mol Sci. 2022 Feb; 23(3): 1368. Published online 2022 Jan 25. doi: 10.3390/ijms23031368

PMCID:: PMC8835787

Abstract Article PDF–3.6M

Select item 882264415.

Genetic polymorphism of ADAM17 and decreased bilirubin levels are associated with allergic march in the Korean population

Jaemee Jung, Dahyun Hwang

BMC Med Genomics. 2022; 15: 21. Published online 2022 Feb 7. doi: 10.1186/s12920-022-01170-7

PMCID:: PMC8822644

Abstract Article PDF–2.1M

Select item 856851316.

ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway

Guoqin Zhu, Jie Liu, Yuan Wang, Naixin Jia, Weiyi Wang, Junhui Zhang, Yi Liang, Hao Tian, Jiaping Zhang

Biomed Res Int. 2021; 2021: 8328216. Published online 2021 Oct 28. doi: 10.1155/2021/8328216

PMCID:: PMC8568513

Abstract Article PDF–2.9M

Select item 839510017.

Severe COVID-19 Patients Show an Increase in Soluble TNFR1 and ADAM17, with a Relationship to Mortality

Yadira Palacios, Andy Ruiz, Lucero A. Ramón-Luing, Ranferi Ocaña-Guzman, Omar Barreto-Rodriguez, Anahí Sánchez-Monciváis, Brenda Tecuatzi-Cadena, Ana G. Regalado-García, Rey David Pineda-Gudiño, Alicia García-Martínez, Fortunato Juárez-Hernández, Juan Pablo Farias-Contreras, Ingrid Fricke-Galindo, Gloria Pérez-Rubio, Ramcés Falfán-Valencia, Ivette Buendia-Roldan, Karen Medina-Quero, Leslie Chavez-Galan

Int J Mol Sci. 2021 Aug; 22(16): 8423. Published online 2021 Aug 5. doi: 10.3390/ijms22168423

PMCID:: PMC8395100

Abstract Article PDF–2.6M

Select item 833956618.

Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation

Hemant K. Mishra, Kate J. Dixon, Nabendu Pore, Martin Felices, Jeffrey S. Miller, Bruce Walcheck

Front Immunol. 2021; 12: 711621. Published online 2021 Jul 22. doi: 10.3389/fimmu.2021.711621

PMCID:: PMC8339566

Abstract Article PDF–1.0M

Select item 826636719.

Molecular switch in human diseases-disintegrin and metalloproteinases, ADAM17

Guang Yang, Mengying Cui, Weibo Jiang, Jiyao Sheng, Yongsheng Yang, Xuewen Zhang

Aging (Albany NY) 2021 Jun 30; 13(12): 16859–16872. Published online 2021 Jun 28. doi: 10.18632/aging.203200

PMCID:: PMC8266367

Abstract Article PDF–592K

Select item 810012820.

Functionally confirmed compound heterozygous ADAM17 missense loss-of-function variants cause neonatal inflammatory skin and bowel disease 1

Issei Imoto, Masako Saito, Kenichi Suga, Tomohiro Kohmoto, Masanobu Otsu, Keisuke Horiuchi, Hironao Nakayama, Shigeki Higashiyama, Mayumi Sugimoto, Ayumi Sasaki, Yukako Homma, Miki Shono, Ryuji Nakagawa, Yasunobu Hayabuchi, Shoichiro Tange, Shoji Kagami, Kiyoshi Masuda

Sci Rep. 2021; 11: 9552. Published online 2021 May 5. doi: 10.1038/s41598-021-89063-0

PMCID:: PMC8100128

Abstract Article PDF–2.4M

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PMC Links for Gene (Select 6868) (257)
PMC
Homo sapiens testis expressed 26 (TEX26), transcript variant 1, mRNA
Homo sapiens testis expressed 26 (TEX26), transcript variant 1, mRNA
gi|1519311876|ref|NM_152325.3|

Nucleotide
PREDICTED: Homo sapiens neuropeptide Y receptor Y1 (NPY1R), transcript variant X...
PREDICTED: Homo sapiens neuropeptide Y receptor Y1 (NPY1R), transcript variant X2, mRNA
gi|2217350806|ref|XM_011532010.4|

Nucleotide

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