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Select item 90631381.

Systematic analysis of prognostic significance, functional enrichment and immune implication of STK10 in acute myeloid leukemia

Lei Bi, Shuangshuang Jia, Wuyue Hu, Xiaoli Su, Xiequn Chen, Hailong Tang

BMC Med Genomics. 2022; 15: 101. Published online 2022 May 1. doi: 10.1186/s12920-022-01251-7

PMCID:: PMC9063138

Abstract Article PDF–4.8M

Select item 72120272.

Sequence Analysis of the Protein Kinase Gene Family in Human Testicular Germ-Cell Tumors of Adolescents and Adults

Graham Bignell, Raffaella Smith, Chris Hunter, Philip Stephens, Helen Davies, Chris Greenman, Jon Teague, Adam Butler, Sarah Edkins, Claire Stevens, Sarah O’Meara, Adrian Parker, Tim Avis, Syd Barthorpe, Lisa Brackenbury, Gemma Buck, Jody Clements, Jennifer Cole, Ed Dicks, Ken Edwards, Simon Forbes, Matthew Gorton, Kristian Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jonathon Hinton, David Jones, Vivienne Kosmidou, Ross Laman, Richard Lugg, Andrew Menzies, Janet Perry, Robert Petty, Keiran Raine, Rebecca Shepherd, Alexandra Small, Helen Solomon, Yvonne Stephens, Calli Tofts, Jennifer Varian, Anthony Webb, Sofie West, Sara Widaa, Andy Yates, Ad J. M. Gillis, Hans J. Stoop, Ruud J. H. L. M. van Gurp, J. Wolter Oosterhuis, Leendert H. J. Looijenga, P. Andrew Futreal, Richard Wooster, Michael R. Stratton

Genes Chromosomes Cancer. Author manuscript; available in PMC 2020 May 11.

Published in final edited form as: Genes Chromosomes Cancer. 2006 Jan 1; 45(1): 42–46. doi: 10.1002/gcc.20265

PMCID:: PMC7212027

Abstract Article PDF–683K

Select item 54005023.

Ezrin activation by LOK phosphorylation involves a PIP₂-dependent wedge mechanism

Thaher Pelaseyed, Raghuvir Viswanatha, Cécile Sauvanet, Joshua J Filter, Michael L Goldberg, Anthony Bretscher

eLife. 2017; 6: e22759. Published online 2017 Apr 21. doi: 10.7554/eLife.22759

PMCID:: PMC5400502

Abstract Article PDF–23M

Select item 12224644.

Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.

Li Tao, Scott Wadsworth, Jason Mercer, Cynthia Mueller, Kirsten Lynn, John Siekierka, Avery August

Biochem J. 2002 Apr 1; 363(Pt 1): 175–182. doi: 10.1042/0264-6021:3630175

PMCID:: PMC1222464

Summary PDF–156K

Select item 35182185.

Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells

Raghuvir Viswanatha, Patrice Y. Ohouo, Marcus B. Smolka, Anthony Bretscher

J Cell Biol. 2012 Dec 10; 199(6): 969–984. doi: 10.1083/jcb.201207047

PMCID:: PMC3518218

Abstract Article PDF–5.1M

Select item 26607626.

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

Natalya V. Belkina, Yin Liu, Jian-Jiang Hao, Hajime Karasuyama, Stephen Shaw

Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12): 4707–4712. Published online 2009 Mar 2. doi: 10.1073/pnas.0805963106

PMCID:: PMC2660762

Abstract Article PDF–865K

Select item 22392687.

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

Ashley C W Pike, Peter Rellos, Frank H Niesen, Andrew Turnbull, Antony W Oliver, Sirlester A Parker, Benjamin E Turk, Laurence H Pearl, Stefan Knapp

EMBO J. 2008 Feb 20; 27(4): 704–714. Published online 2008 Jan 31. doi: 10.1038/emboj.2008.8

PMCID:: PMC2239268

Abstract Article PDF–545K

Select item 29928488.

A Three-Stage Genome-Wide Association Study of General Cognitive Ability: Hunting the Small Effects

Oliver S. P. Davis, Lee M. Butcher, Sophia J. Docherty, Emma L. Meaburn, Charles J. C. Curtis, Michael A. Simpson, Leonard C. Schalkwyk, Robert Plomin

Behav Genet. 2010; 40(6): 759–767. Published online 2010 Mar 21. doi: 10.1007/s10519-010-9350-4

PMCID:: PMC2992848

Abstract Article PDF–376K

Select item 40411239.

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Verneri Anttila, Bendik S. Winsvold, Padhraig Gormley, Tobias Kurth, Francesco Bettella, George McMahon, Mikko Kallela, Rainer Malik, Boukje de Vries, Gisela Terwindt, Sarah E. Medland, Unda Todt, Wendy L. McArdle, Lydia Quaye, Markku Koiranen, M. Arfan Ikram, Terho Lehtimäki, Anine H. Stam, Lannie Ligthart, Juho Wedenoja, Ian Dunham, Benjamin M. Neale, Priit Palta, Eija Hamalainen, Markus Schürks, Lynda M Rose, Julie E. Buring, Paul M. Ridker, Stacy Steinberg, Hreinn Stefansson, Finnbogi Jakobsson, Debbie A. Lawlor, David M. Evans, Susan M. Ring, Markus Färkkilä, Ville Artto, Mari A Kaunisto, Tobias Freilinger, Jean Schoenen, Rune R. Frants, Nadine Pelzer, Claudia M. Weller, Ronald Zielman, Andrew C. Heath, Pamela A.F. Madden, Grant W. Montgomery, Nicholas G. Martin, Guntram Borck, Hartmut Göbel, Axel Heinze, Katja Heinze-Kuhn, Frances M.K. Williams, Anna-Liisa Hartikainen, Anneli Pouta, Joyce van den Ende, Andre G. Uitterlinden, Albert Hofman, Najaf Amin, Jouke-Jan Hottenga, Jacqueline M. Vink, Kauko Heikkilä, Michael Alexander, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Heinz Erich Wichmann, Arpo Aromaa, Johan G. Eriksson, Bryan Traynor, Daniah Trabzuni, North American Brain Expression Consortium, UK Brain Expression Consortium, Elizabeth Rossin, Kasper Lage, Suzanne B.R. Jacobs, J. Raphael Gibbs, Ewan Birney, Jaakko Kaprio, Brenda W. Penninx, Dorret I. Boomsma, Cornelia van Duijn, Olli Raitakari, Marjo-Riitta Jarvelin, John-Anker Zwart, Lynn Cherkas, David P. Strachan, Christian Kubisch, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Martin Dichgans, Maija Wessman, George Davey Smith, Kari Stefansson, Mark J. Daly, Dale R. Nyholt, Daniel Chasman, Aarno Palotie

Nat Genet. Author manuscript; available in PMC 2014 Jun 2.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 912–917. Published online 2013 Jun 23. doi: 10.1038/ng.2676

PMCID:: PMC4041123

Article PDF–571K

Select item 363685610.

The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes

Daniel Perez-Hernandez, Cristina Gutiérrez-Vázquez, Inmaculada Jorge, Soraya López-Martín, Angeles Ursa, Francisco Sánchez-Madrid, Jesús Vázquez, María Yáñez-Mó

J Biol Chem. 2013 Apr 26; 288(17): 11649–11661. Published online 2013 Mar 5. doi: 10.1074/jbc.M112.445304

PMCID:: PMC3636856

Abstract Article PDF–4.6M

Select item 629825411.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 1032325212.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 1091686613.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 876907214.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 638658815.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 895155616.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 51444617.

Large-scale characterization of HeLa cell nuclear phosphoproteins

Sean A. Beausoleil, Mark Jedrychowski, Daniel Schwartz, Joshua E. Elias, Judit Villén, Jiaxu Li, Martin A. Cohn, Lewis C. Cantley, Steven P. Gygi

Proc Natl Acad Sci U S A. 2004 Aug 17; 101(33): 12130–12135. Published online 2004 Aug 9. doi: 10.1073/pnas.0404720101

PMCID:: PMC514446

Abstract Article PDF–475K

Select item 1007290618.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 509804119.

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions

Charles A. S. Banks, Gina Boanca, Zachary T. Lee, Cassandra G. Eubanks, Gaye L. Hattem, Allison Peak, Lauren E. Weems, Juliana J. Conkright, Laurence Florens, Michael P. Washburn

Mol Cell Proteomics. 2016 Nov; 15(11): 3435–3449. Published online 2016 Sep 8. doi: 10.1074/mcp.M116.060509

PMCID:: PMC5098041

Abstract Article PDF–2.1M

Select item 822039120.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

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