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Items: 1 to 20 of 164

1.
STAT6 mutations enriched at diffuse large B-cell lymphoma relapse reshape the tumor microenvironment
Alexandre Benoit, Madelyn J. Abraham, Sheena Li, John Kim, Roger Estrada-Tejedor, Rowa Bakadlag, Nivetha Subramaniam, Kiran Makhani, Cynthia Guilbert, Raymond Tu, Matthew Salaciak, Kathleen Oros Klein, Krysta Mila Coyle, Laura K. Hilton, Raoul Santiago, Svetlana Dmitrienko, Sarit Assouline, Ryan D. Morin, Sonia V. del Rincon, Nathalie A. Johnson, Koren K. Mann
Int J Hematol. 2024; 119(3): 275–290. Published online 2024 Jan 29. doi: 10.1007/s12185-023-03692-x
PMCID:
PMC10920476
AbstractArticlePDF–4.5M
2.
Autosomal Dominant STAT6 Gain of Function Causes Severe Atopy Associated with Lymphoma
Ekaterina Minskaia, Jesmeen Maimaris, Persephone Jenkins, Adriana S. Albuquerque, Ying Hong, Despina Eleftheriou, Kimberly C. Gilmour, Richard Grace, Fernando Moreira, Bodo Grimbacher, NIHR Bioresource-Rare Diseases Consortium, Emma C. Morris, Siobhan O. Burns
J Clin Immunol. 2023; 43(7): 1611–1622. Published online 2023 Jun 14. doi: 10.1007/s10875-023-01530-7
PMCID:
PMC10499697
AbstractArticlePDF–6.2M
3.
Severe Allergic Dysregulation Due to A Gain of Function Mutation in the Transcription Factor STAT6
Safa Baris, Mehdi Benamar, Qian Chen, Mehmet Cihangir Catak, Mónica Martínez-Blanco, Muyun Wang, Jason Fong, Michel J. Massaad, Asena Pinar Sefer, Altan Kara, Royala Babayeva, Sevgi Bilgic Eltan, Ayse Deniz Yucelten, Emine Bozkurtlar, Leyla Cinel, Elif Karakoc-Aydiner, Yumei Zheng, Hao Wu, Ahmet Ozen, Klaus Schmitz-Abe, Talal A. Chatila
J Allergy Clin Immunol. Author manuscript; available in PMC 2024 Jul 1.
Published in final edited form as: J Allergy Clin Immunol. 2023 Jul; 152(1): 182–194.e7. Published online 2023 Feb 8. doi: 10.1016/j.jaci.2023.01.023
PMCID:
PMC10330134
AbstractArticlePDF–2.5M
4.
Learning while treating: Gain-of-function STAT6 variants in severe allergic disease
Tukisa D. Smith, Taylor A. Doherty
Cell Rep Med. 2023 May 16; 4(5): 101040. Published online 2023 May 16. doi: 10.1016/j.xcrm.2023.101040
PMCID:
PMC10213836
AbstractArticlePDF–197K
5.
Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease
Mehul Sharma, Daniel Leung, Mana Momenilandi, Lauren C.W. Jones, Lucia Pacillo, Alyssa E. James, Jill R. Murrell, Selket Delafontaine, Jesmeen Maimaris, Maryam Vaseghi-Shanjani, Kate L. Del Bel, Henry Y. Lu, Gilbert T. Chua, Silvia Di Cesare, Oriol Fornes, Zhongyi Liu, Gigliola Di Matteo, Maggie P. Fu, Donato Amodio, Issan Yee San Tam, Gavin Shueng Wai Chan, Ashish A. Sharma, Joshua Dalmann, Robin van der Lee, Géraldine Blanchard-Rohner, Susan Lin, Quentin Philippot, Phillip A. Richmond, Jessica J. Lee, Allison Matthews, Michael Seear, Alexandra K. Turvey, Rachael L. Philips, Terri F. Brown-Whitehorn, Christopher J. Gray, Kosuke Izumi, James R. Treat, Kathleen H. Wood, Justin Lack, Asya Khleborodova, Julie E. Niemela, Xingtian Yang, Rui Liang, Lin Kui, Christina Sze Man Wong, Grace Wing Kit Poon, Alexander Hoischen, Caspar I. van der Made, Jing Yang, Koon Wing Chan, Jaime Sou Da Rosa Duque, Pamela Pui Wah Lee, Marco Hok Kung Ho, Brian Hon Yin Chung, Huong Thi Minh Le, Wanling Yang, Pejman Rohani, Ali Fouladvand, Hassan Rokni-Zadeh, Majid Changi-Ashtiani, Mohammad Miryounesi, Anne Puel, Mohammad Shahrooei, Andrea Finocchi, Paolo Rossi, Beatrice Rivalta, Cristina Cifaldi, Antonio Novelli, Chiara Passarelli, Stefania Arasi, Dominique Bullens, Kate Sauer, Tania Claeys, Catherine M. Biggs, Emma C. Morris, Sergio D. Rosenzweig, John J. O’Shea, Wyeth W. Wasserman, H. Melanie Bedford, Clara D.M. van Karnebeek, Paolo Palma, Siobhan O. Burns, Isabelle Meyts, Jean-Laurent Casanova, Jonathan J. Lyons, Nima Parvaneh, Anh Thi Van Nguyen, Caterina Cancrini, Jennifer Heimall, Hanan Ahmed, Margaret L. McKinnon, Yu Lung Lau, Vivien Béziat, Stuart E. Turvey
J Exp Med. 2023 May 1; 220(5): e20221755. Published online 2023 Mar 8. doi: 10.1084/jem.20221755
PMCID:
PMC10037107
AbstractArticlePDF–7.8M
6.
Patterns of Inflammatory Cell Infiltration and Expression of STAT6 in the Lungs of Patients With COVID-19: An Autopsy Study
Weibiao Cao, Mark Birkenbach, Sonja Chen
Appl Immunohistochem Mol Morphol. 2022 May-Jun; 30(5): 350–357. Published online 2022 Apr 4. doi: 10.1097/PAI.0000000000001023
PMCID:
PMC9066507
AbstractArticlePDF–343K
7.
Loss of STAT6 leads to anchorage-independent growth and trastuzumab resistance in HER2+ breast cancer cells
Molly DiScala, Matthew S. Najor, Timothy Yung, Deri Morgan, Abde M. Abukhdeir, Melody A. Cobleigh
PLoS One. 2020; 15(6): e0234146. Published online 2020 Jun 11. doi: 10.1371/journal.pone.0234146
PMCID:
PMC7289443
AbstractArticlePDF–1.2M
8.
Solitary fibrous tumor of the orbit: A case series with clinicopathologic correlation and evaluation of STAT6 as a diagnostic marker
Nathan W. Blessing, J. Antonio Bermudez-Magner, Maria P. Fernandez, Andrew E. Rosenberg, Sander R. Dubovy, Thomas E. Johnson
Ophthalmic Plast Reconstr Surg. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: Ophthalmic Plast Reconstr Surg. 2020 Mar-Apr; 36(2): 164–171. doi: 10.1097/IOP.0000000000001504
PMCID:
PMC7060103
AbstractArticlePDF–1.2M
9.
Human Embryonic Stem Cell-Derived Cardiovascular Progenitors Repair Infarcted Hearts Through Modulation of Macrophages via Activation of Signal Transducer and Activator of Transcription 6
Jinxi Wang, Meilan Liu, Qiang Wu, Qiang Li, Ling Gao, Yun Jiang, Boxiong Deng, Wei Huang, Wei Bi, Zhongyan Chen, Y. Eugene Chin, Christian Paul, Yigang Wang, Huang-Tian Yang
Antioxid Redox Signal. 2019 Aug 10; 31(5): 369–386. Published online 2019 Jun 25. doi: 10.1089/ars.2018.7688
PMCID:
PMC6602123
AbstractArticlePDF–68M
10.
STAT6 knockdown using multiple siRNA sequences inhibits proliferation and induces apoptosis of human colorectal and breast cancer cell lines
Carmen Salguero-Aranda, Daniel Sancho-Mensat, Beatriz Canals-Lorente, Sabena Sultan, Ajan Reginald, Lee Chapman
PLoS One. 2019; 14(5): e0207558. Published online 2019 May 10. doi: 10.1371/journal.pone.0207558
Expression of Concern in:
PLoS One. 2021; 16(1): e0246415.
PMCID:
PMC6510441
AbstractArticlePDF–3.1M
11.
Association of STAT6 gene variants with food allergy diagnosed by double‐blind placebo‐controlled food challenges
C. D. van Ginkel, M. E. Pettersson, A. E. J. Dubois, G. H. Koppelman
Allergy. 2018 Jun; 73(6): 1337–1341. Published online 2018 Apr 6. doi: 10.1111/all.13432
PMCID:
PMC6032865
AbstractArticlePDF–252K
12.
STAT6 Reliably Distinguishes Solitary Fibrous Tumors from Myofibromas
Molly Housley Smith, Nadim M. Islam, Indraneel Bhattacharyya, Donald M. Cohen, Sarah G. Fitzpatrick
Head Neck Pathol. 2018 Mar; 12(1): 110–117. Published online 2017 Jul 8. doi: 10.1007/s12105-017-0836-8
PMCID:
PMC5873490
AbstractArticlePDF–2.7M
13.
Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6
Luigi Russo, Karin Giller, Edith Pfitzner, Christian Griesinger, Stefan Becker
Sci Rep. 2017; 7: 16845. Published online 2017 Dec 4. doi: 10.1038/s41598-017-17088-5
PMCID:
PMC5714956
AbstractArticlePDF–3.9M
14.
N4 DNA recognition by STAT6: structural and functional implications
Xiang Zhou, Zhengfan Jiang
Protein Cell. 2017 Apr; 8(4): 240–241. Published online 2017 Feb 20. doi: 10.1007/s13238-017-0380-z
PMCID:
PMC5359187
ArticlePDF–309K
15.
Nuclear Localization and Cleavage of STAT6 Is Induced by Kaposi’s Sarcoma-Associated Herpesvirus for Viral Latency
Chong Wang, Caixia Zhu, Fang Wei, Shujun Gao, Liming Zhang, Yuhong Li, Yanling Feng, Yin Tong, Jianqing Xu, Bin Wang, Zhenghong Yuan, Erle S. Robertson, Qiliang Cai
PLoS Pathog. 2017 Jan; 13(1): e1006124. Published online 2017 Jan 18. doi: 10.1371/journal.ppat.1006124
Expression of Concern in:
PLoS Pathog. 2021 Dec; 17(12): e1010047.
PMCID:
PMC5242515
AbstractArticlePDF–5.9M
16.
Structural basis for DNA recognition by STAT6
Jing Li, Jose Pindado Rodriguez, Fengfeng Niu, Mengchen Pu, Jinan Wang, Li-Wei Hung, Qiang Shao, Yanping Zhu, Wei Ding, Yanqing Liu, Yurong Da, Zhi Yao, Jie Yang, Yongfang Zhao, Gong-Hong Wei, Genhong Cheng, Zhi-Jie Liu, Songying Ouyang
Proc Natl Acad Sci U S A. 2016 Nov 15; 113(46): 13015–13020. Published online 2016 Nov 1. doi: 10.1073/pnas.1611228113
PMCID:
PMC5135355
AbstractArticlePDF–1.2M
17.
Activating STAT6 mutations in follicular lymphoma
Mehmet Yildiz, Hongxiu Li, Denzil Bernard, Nisar A. Amin, Peter Ouillette, Siân Jones, Kamlai Saiya-Cork, Brian Parkin, Kathryn Jacobi, Kerby Shedden, Shaomeng Wang, Alfred E. Chang, Mark S. Kaminski, Sami N. Malek
Blood. 2015 Jan 22; 125(4): 668–679. Prepublished online 2014 Nov 26. doi: 10.1182/blood-2014-06-582650
PMCID:
PMC4729538
AbstractArticle
18.
EXTENSIVE SURVEY OF STAT6 EXPRESSION IN A LARGE SERIES OF MESENCHYMAL TUMORS
Elizabeth G Demicco, Paul W Harms, Rajiv M Patel, Steven C Smith, Davis Ingram, Keila Torres, Shannon L Carskadon, Sandra Camelo-Piragua, Jonathan B McHugh, Javed Siddiqui, Nallasivam Palanisamy, David R Lucas, Alexander J Lazar, Wei-lien Wang
Am J Clin Pathol. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Am J Clin Pathol. 2015 May; 143(5): 672–682. doi: 10.1309/AJCPN25NJTOUNPNF
PMCID:
PMC4505928
AbstractArticlePDF–3.1M
19.
STAT6-Dependent Collagen Synthesis in Human Fibroblasts Is Induced by Bovine Milk
Stefan Kippenberger, Nadja Zöller, Johannes Kleemann, Jutta Müller, Roland Kaufmann, Matthias Hofmann, August Bernd, Markus Meissner, Eva Valesky
PLoS One. 2015; 10(7): e0131783. Published online 2015 Jul 2. doi: 10.1371/journal.pone.0131783
PMCID:
PMC4489876
AbstractArticlePDF–3.4M
20.
The Correlation Analysis of Two Common Polymorphisms in STAT6 Gene and the Risk of Asthma: A Meta-Analysis
Li Zhu, Qingqing Zhu, Xinlin Zhang, Hongwei Wang
PLoS One. 2013; 8(7): e67657. Published online 2013 Jul 4. doi: 10.1371/journal.pone.0067657
PMCID:
PMC3701693
AbstractArticlePDF–1.0M

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