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Select item 63249701.

Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1

Kathryn A. Radigan, Trevor T. Nicholson, Lynn C. Welch, Monica Chi, Luciano Amarelle, Martín Angulo, Masahiko Shigemura, Atsuko Shigemura, Constance E. Runyan, Luisa Morales-Nebreda, Harris Perlman, Ermelinda Ceco, Emilia Lecuona, Laura A. Dada, Alexander V. Misharin, Gokhan M. Mutlu, Jacob I. Sznajder, G.R. Scott Budinger

J Immunol. Author manuscript; available in PMC 2020 Jan 15.

Published in final edited form as: J Immunol. 2019 Jan 15; 202(2): 484–493. Published online 2018 Dec 7. doi: 10.4049/jimmunol.1701433

PMCID:: PMC6324970

Abstract Article PDF–1.8M

Select item 60268012.

Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo

Roberto Mota, Traci L. Parry, Cecelia C. Yates, Zhaoyan Qiang, Samuel C. Eaton, Jean Marie Mwiza, Deepthi Tulasi, Jonathan C. Schisler, Cam Patterson, Tania Zaglia, Marco Sandri, Monte S. Willis

Am J Pathol. 2018 Jul; 188(7): 1676–1692. doi: 10.1016/j.ajpath.2018.04.007

PMCID:: PMC6026801

Abstract Article

Select item 40385603.

Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy

Tania Zaglia, Giulia Milan, Aaron Ruhs, Mauro Franzoso, Enrico Bertaggia, Nicola Pianca, Andrea Carpi, Pierluigi Carullo, Paola Pesce, David Sacerdoti, Cristiano Sarais, Daniele Catalucci, Marcus Krüger, Marco Mongillo, Marco Sandri

J Clin Invest. 2014 Jun 2; 124(6): 2410–2424. Published online 2014 May 1. doi: 10.1172/JCI66339

PMCID:: PMC4038560

Abstract Article PDF–8.8M

Select item 109381244.

ROS in diabetic atria regulate SK2 degradation by Atrogin-1 through the NF-κB signaling pathway

Jian Xu, Dong Zhang, Yibo Ma, Hui Du, Yi Wang, Wenping Luo, Ruxing Wang, Fu Yi

J Biol Chem. 2024 Mar; 300(3): 105735. Published online 2024 Feb 8. doi: 10.1016/j.jbc.2024.105735

PMCID:: PMC10938124

Abstract Article PDF–3.6M

Select item 107178765.

Differential gene expression of muscle-specific ubiquitin ligase MAFbx/Atrogin-1 and MuRF1 in response to immobilization-induced atrophy of slow-twitch and fast-twitch muscles

Takeshi Okamoto, Suguru Torii, Shuichi Machida

J Physiol Sci. 2011 Nov; 61(6): 537. Published online 2011 Sep 8. doi: 10.1007/s12576-011-0175-6

PMCID:: PMC10717876

Abstract Article PDF–1.7M

Select item 64220736.

F-box protein-32 down-regulates small-conductance calcium-activated potassium channel 2 in diabetic mouse atria

Tian-You Ling, Fu Yi, Tong Lu, Xiao-Li Wang, Xiaojing Sun, Monte S. Willis, Li-Qun Wu, Win-Kuang Shen, John P. Adelman, Hon-Chi Lee

J Biol Chem. 2019 Mar 15; 294(11): 4160–4168. Published online 2019 Jan 11. doi: 10.1074/jbc.RA118.003837

PMCID:: PMC6422073

Abstract Article PDF–2.2M

Select item 62866537.

Day-Night Oscillation of Atrogin1 and Timing-Dependent Preventive Effect of Weight-Bearing on Muscle Atrophy

Shinya Aoyama, Shuichi Kojima, Keisuke Sasaki, Ryosuke Ishikawa, Mizuho Tanaka, Takeru Shimoda, Yuta Hattori, Natsumi Aoki, Kengo Takahashi, Rina Hirooka, Miku Takizawa, Atsushi Haraguchi, Shigenobu Shibata

EBioMedicine. 2018 Nov; 37: 499–508. Published online 2018 Nov 1. doi: 10.1016/j.ebiom.2018.10.057

PMCID:: PMC6286653

Abstract Article PDF–3.0M

Select item 56228008.

Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1

Hung-Wen Liu, Yen-Ju Chen, Yun-Ching Chang, Sue-Joan Chang

Nutrients. 2017 Sep; 9(9): 1040. Published online 2017 Sep 20. doi: 10.3390/nu9091040

PMCID:: PMC5622800

Abstract Article PDF–2.9M

Select item 49940889.

Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

Yuki Enoki, Hiroshi Watanabe, Riho Arake, Ryusei Sugimoto, Tadashi Imafuku, Yuna Tominaga, Yu Ishima, Shunsuke Kotani, Makoto Nakajima, Motoko Tanaka, Kazutaka Matsushita, Masafumi Fukagawa, Masaki Otagiri, Toru Maruyama

Sci Rep. 2016; 6: 32084. Published online 2016 Aug 23. doi: 10.1038/srep32084

PMCID:: PMC4994088

Abstract Article PDF–1.8M

Select item 485950710.

PABPN1-Dependent mRNA Processing Induces Muscle Wasting

Muhammad Riaz, Yotam Raz, Maaike van Putten, Guillem Paniagua-Soriano, Yvonne D. Krom, Bogdan I. Florea, Vered Raz

PLoS Genet. 2016 May; 12(5): e1006031. Published online 2016 May 6. doi: 10.1371/journal.pgen.1006031

PMCID:: PMC4859507

Abstract Article PDF–5.9M

Select item 403733011.

MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart

Kedryn K. Baskin, Meredith R. Rodriguez, Seema Kansara, Wenhao Chen, Sylvia Carranza, O. Howard Frazier, David J. Glass, Heinrich Taegtmeyer

J Mol Cell Cardiol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Mol Cell Cardiol. 2014 Jul; 72: 168–176. Published online 2014 Mar 18. doi: 10.1016/j.yjmcc.2014.03.006

PMCID:: PMC4037330

Abstract Article PDF–1.0M

Select item 338209612.

Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation

Aldrin V. Gomes, Dave S. Waddell, Rylie Siu, Matthew Stein, Shannamar Dewey, J. David Furlow, Sue C. Bodine

FASEB J. 2012 Jul; 26(7): 2986–2999. doi: 10.1096/fj.12-204495

PMCID:: PMC3382096

Abstract Article

Select item 321342213.

Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids

Leslie M Baehr, J David Furlow, Sue C Bodine

J Physiol. 2011 Oct 1; 589(Pt 19): 4759–4776. Published online 2011 Aug 1. doi: 10.1113/jphysiol.2011.212845

PMCID:: PMC3213422

Abstract Article PDF–452K

Select item 305712614.

Myocardial dysfunction in an animal model of cancer cachexia

Hui Xu, Danielle Crawford, Kirk R. Hutchinson, Dane J. Youtz, Pamela A. Lucchesi, Markus Velten, Donna O. McCarthy, Loren E. Wold

Life Sci. Author manuscript; available in PMC 2012 Feb 28.

Published in final edited form as: Life Sci. 2011 Feb 28; 88(9-10): 406–410. Published online 2010 Dec 14. doi: 10.1016/j.lfs.2010.12.010

PMCID:: PMC3057126

Abstract Article PDF–1.0M

Select item 291107515.

Atrogin-1 Affects Muscle Protein Synthesis and Degradation When Energy Metabolism Is Impaired by the Antidiabetes Drug Berberine

Huiling Wang, Dajun Liu, Peirang Cao, Stewart Lecker, Zhaoyong Hu

Diabetes. 2010 Aug; 59(8): 1879–1889. Published online 2010 Jun 3. doi: 10.2337/db10-0207

PMCID:: PMC2911075

Abstract Article PDF–691K

Select item 204031616.

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

Hui-Hua Li, Monte S. Willis, Pamela Lockyer, Nathaniel Miller, Holly McDonough, David J. Glass, Cam Patterson

J Clin Invest. 2007 Nov 1; 117(11): 3211–3223. Published online 2007 Oct 25. doi: 10.1172/JCI31757

Correction in:: J Clin Invest. 2022 Jan 4; 132(1): e157373.

PMCID:: PMC2040316

Abstract Article PDF–1.6M

Select item 813092617.

Activation of the β-adrenergic receptor exacerbates lipopolysaccharide-induced wasting of skeletal muscle cells by increasing interleukin-6 production

Shino Matsukawa, Shinichi Kai, Hideya Seo, Kengo Suzuki, Kazuhiko Fukuda

PLoS One. 2021; 16(5): e0251921. Published online 2021 May 18. doi: 10.1371/journal.pone.0251921

PMCID:: PMC8130926

Abstract Article PDF–3.0M

Select item 380585218.

Smad3 Induces Atrogin-1, Inhibits mTOR and Protein Synthesis, and Promotes Muscle Atrophy In Vivo

Craig A. Goodman, Rachel M. McNally, F. Michael Hoffmann, Troy A. Hornberger

Mol Endocrinol. 2013 Nov; 27(11): 1946–1957. Published online 2013 Sep 3. doi: 10.1210/me.2013-1194

PMCID:: PMC3805852

Abstract Article

Select item 363243619.

The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling

Carsten Skurk, Yasuhiro Izumiya, Henrike Maatz, Peter Razeghi, Ichiro Shiojima, Marco Sandri, Kaori Sato, Ling Zeng, Stephan Schiekofer, David Pimentel, Stewart Lecker, Heinrich Taegtmeyer, Alfred L. Goldberg, Kenneth Walsh

J Biol Chem. Author manuscript; available in PMC 2013 Apr 22.

Published in final edited form as: J Biol Chem. 2005 May 27; 280(21): 20814–20823. Published online 2005 Mar 21. doi: 10.1074/jbc.M500528200

PMCID:: PMC3632436

Abstract Article PDF–2.3M

Select item 319938220.

C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting

Guohua Zhang, Bingwen Jin, Yi-Ping Li

EMBO J. 2011 Oct 19; 30(20): 4323–4335. Published online 2011 Aug 16. doi: 10.1038/emboj.2011.292

PMCID:: PMC3199382

Abstract Article PDF–2.0M

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