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Select item 105061081.

In vivo CRISPR/Cas9 screening identifies Pbrm1 as a regulator of myeloid leukemia development in mice

Bin E. Li, Grace Y. Li, Wenqing Cai, Qian Zhu, Davide Seruggia, Yuko Fujiwara, Christopher R. Vakoc, Stuart H. Orkin

Blood Adv. 2023 Sep 26; 7(18): 5281–5293. Published online 2023 Jul 12. doi: 10.1182/bloodadvances.2022009455

PMCID:: PMC10506108

Abstract Article PDF–2.9M

Select item 93448232.

Pbrm1 intrinsically controls the development and effector differentiation of iNKT cells

Xin Wang, Lei Lei, Yanhong Su, Jun Liu, Ning Yuan, Yang Gao, Xiaofeng Yang, Chenming Sun, Bin Ning, Baojun Zhang

J Cell Mol Med. 2022 Aug; 26(15): 4268–4276. Published online 2022 Jun 29. doi: 10.1111/jcmm.17445

PMCID:: PMC9344823

Abstract Article PDF–1.4M

Select item 33138583.

IL-10 transcription is negatively regulated by BAF180, a component of the SWI/SNF chromatin remodeling enzyme

Andrea L Wurster, Patricia Precht, Kevin G Becker, William H Wood, III, Yongqing Zhang, Zhong Wang, Michael J Pazin

BMC Immunol. 2012; 13: 9. Published online 2012 Feb 15. doi: 10.1186/1471-2172-13-9

PMCID:: PMC3313858

Abstract Article PDF–1.4M

Select item 75490164.

Bap1 and Pbrm1: Determinants of Tumor Grade and mTOR Activation in VHL-Deficient Mouse Models of Renal Cell Carcinoma

Janet Y. Leung, William Y. Kim

Cancer Discov. Author manuscript; available in PMC 2020 Oct 12.

Published in final edited form as: Cancer Discov. 2017 Aug; 7(8): 802–804. doi: 10.1158/2159-8290.CD-17-0610

PMCID:: PMC7549016

Abstract Article PDF–438K

Select item 57254505.

Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis

Judit Espana-Agusti, Anne Warren, Su Kit Chew, David J. Adams, Athena Matakidou

Nat Commun. 2017; 8: 2026. Published online 2017 Dec 11. doi: 10.1038/s41467-017-02245-1

PMCID:: PMC5725450

Abstract Article PDF–3.5M

Select item 49913716.

BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

Hyemin Lee, Fangyan Dai, Li Zhuang, Zhen-Dong Xiao, Jongchan Kim, Yilei Zhang, Li Ma, M. James You, Zhong Wang, Boyi Gan

Oncotarget. 2016 Apr 12; 7(15): 19134–19146. Published online 2016 Mar 15. doi: 10.18632/oncotarget.8102

PMCID:: PMC4991371

Abstract Article PDF–5.7M

Select item 109040577.

Stromal Pbrm1 mediates chromatin remodeling necessary for embryo implantation in the mouse uterus

Qiliang Xin, Iris Feng, Guoyun Yu, Jurrien Dean

J Clin Invest. 2024 Mar 1; 134(5): e174194. Published online 2024 Mar 1. doi: 10.1172/JCI174194

PMCID:: PMC10904057

Abstract Article PDF–18M

Select item 54310848.

The SWI/SNF Protein PBRM1 Restrains VHL Loss-Driven Clear Cell Renal Cell Carcinoma

Amrita M. Nargund, Can G. Pham, Yiyu Dong, Patricia I. Wang, Hatice U. Osmangeyoglu, Yuchen Xie, Omer Aras, Song Han, Toshinao Oyama, Shugaku Takeda, Chelsea E. Ray, Zhenghong Dong, Mathieu Berge, A Ari Hakimi, Sebastien Monette, Carl L. Lekaye, Jason A. Koutcher, Christina S. Leslie, Chad J. Creighton, Nils Weinhold, William Lee, Satish K. Tickoo, Zhong Wang, Emily H. Cheng, James J. Hsieh

Cell Rep. Author manuscript; available in PMC 2017 May 15.

Published in final edited form as: Cell Rep. 2017 Mar 21; 18(12): 2893–2906. doi: 10.1016/j.celrep.2017.02.074

PMCID:: PMC5431084

Abstract Article PDF–3.0M

Select item 55407769.

Modeling Renal Cell Carcinoma in mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade

Yi-Feng Gu, Shannon Cohn, Alana Christie, Tiffani McKenzie, Nicholas Wolff, Quyen N. Do, Ananth J. Madhuranthakam, Ivan Pedrosa, Tao Wang, Anwesha Dey, Meinrad Busslinger, Xian-Jin Xie, Robert E. Hammer, Renée M. McKay, Payal Kapur, James Brugarolas

Cancer Discov. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Cancer Discov. 2017 Aug; 7(8): 900–917. Published online 2017 May 4. doi: 10.1158/2159-8290.CD-17-0292

PMCID:: PMC5540776

Abstract Article PDF–1.8M

Select item 398883810.

BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy

Peter M. Brownlee, Anna L. Chambers, Ross Cloney, Alessandro Bianchi, Jessica A. Downs

Cell Rep. 2014 Mar 27; 6(6): 973–981. Published online 2014 Mar 6. doi: 10.1016/j.celrep.2014.02.012

PMCID:: PMC3988838

Abstract Article

Select item 963715811.

The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis

Pengfei Guo, Nam Hoang, Joseph Sanchez, Elaine H. Zhang, Keshari Rajawasam, Kristiana Trinidad, Hong Sun, Hui Zhang

Nat Commun. 2022; 13: 6696. Published online 2022 Nov 5. doi: 10.1038/s41467-022-34348-9

PMCID:: PMC9637158

Abstract Article PDF–3.3M

Select item 734182112.

A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function

Chin-San Loo, Jovylyn Gatchalian, Yuqiong Liang, Mathias Leblanc, Mingjun Xie, Josephine Ho, Bhargav Venkatraghavan, Diana C. Hargreaves, Ye Zheng

Immunity. 2020 Jul 14; 53(1): 143–157.e8. Published online 2020 Jul 7. doi: 10.1016/j.immuni.2020.06.011

PMCID:: PMC7341821

Abstract Article PDF–4.7M

Select item 306087413.

Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development

Masahito Kawazu, Kayoko Saso, Kit I. Tong, Tracy McQuire, Kouichiro Goto, Dong-Ok Son, Andrew Wakeham, Makoto Miyagishi, Tak W. Mak, Hitoshi Okada

PLoS One. 2011; 6(3): e17830. Published online 2011 Mar 18. doi: 10.1371/journal.pone.0017830

Correction in:: PLoS One. 2024; 19(5): e0303780.

PMCID:: PMC3060874

Abstract Article PDF–1.8M

Select item 53592014.

Polybromo protein BAF180 functions in mammalian cardiac chamber maturation

Zhong Wang, Weiguo Zhai, James A. Richardson, Eric N. Olson, Juanito J. Meneses, Meri T. Firpo, Chulho Kang, William C. Skarnes, Robert Tjian

Genes Dev. 2004 Dec 15; 18(24): 3106–3116. doi: 10.1101/gad.1238104

PMCID:: PMC535920

Abstract Article PDF–362K

Select item 960625315.

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

Sasha L. Fulton, Wendy Wenderski, Ashley E. Lepack, Andrew L. Eagle, Tomas Fanutza, Ryan M. Bastle, Aarthi Ramakrishnan, Emma C. Hays, Arianna Neal, Jaroslav Bendl, Lorna A. Farrelly, Amni Al-Kachak, Yang Lyu, Bulent Cetin, Jennifer C. Chan, Tina N. Tran, Rachael L. Neve, Randall J. Roper, Kristen J. Brennand, Panos Roussos, John C. Schimenti, Allyson K. Friedman, Li Shen, Robert D. Blitzer, Alfred J. Robison, Gerald R. Crabtree, Ian Maze

Nat Commun. 2022; 13: 6384. Published online 2022 Oct 26. doi: 10.1038/s41467-022-34200-0

PMCID:: PMC9606253

Abstract Article PDF–4.0M

Select item 795509816.

Interplay of BAF and MLL4 promotes cell type-specific enhancer activation

Young-Kwon Park, Ji-Eun Lee, Zhijiang Yan, Kaitlin McKernan, Tommy O’Haren, Weidong Wang, Weiqun Peng, Kai Ge

Nat Commun. 2021; 12: 1630. Published online 2021 Mar 12. doi: 10.1038/s41467-021-21893-y

PMCID:: PMC7955098

Abstract Article PDF–5.5M

Select item 1029640317.

PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development

Vanessa Waldhauser, Tina Baroti, Franziska Fröb, Michael Wegner

Cells. 2023 Jun; 12(12): 1556. Published online 2023 Jun 6. doi: 10.3390/cells12121556

PMCID:: PMC10296403

Abstract Article PDF–20M

Select item 405383518.

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

Lucia Daxinger, Sarah K Harten, Harald Oey, Trevor Epp, Luke Isbel, Edward Huang, Nadia Whitelaw, Anwyn Apedaile, Anabel Sorolla, Joan Yong, Vandhana Bharti, Joanne Sutton, Alyson Ashe, Zhenyi Pang, Nathan Wallace, Daniel J Gerhardt, Marnie E Blewitt, Jeffrey A Jeddeloh, Emma Whitelaw

Genome Biol. 2013; 14(9): R96. Published online 2013 Sep 11. doi: 10.1186/gb-2013-14-9-r96