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Select item 110211971.

Glucose controls lipolysis through Golgi PtdIns4P-mediated regulation of ATGL

Lianggong Ding, Florian Huwyler, Fen Long, Wu Yang, Jonas Binz, Kendra Wernlé, Matthias Pfister, Manuel Klug, Miroslav Balaz, Barbara Ukropcova, Jozef Ukropec, Chunyan Wu, Tongtong Wang, Min Gao, Pierre-Alain Clavien, Philipp Dutkowski, Mark W. Tibbitt, Christian Wolfrum

Nat Cell Biol. 2024; 26(4): 552–566. Published online 2024 Apr 1. doi: 10.1038/s41556-024-01386-y

PMCID:: PMC11021197

Abstract Article PDF–31M

Select item 105908662.

Sympathetic overdrive and unrestrained adipose lipolysis drive alcohol-induced hepatic steatosis in rodents

Chunxue Zhou, Henry H. Ruiz, Li Ling, Giulia Maurizi, Kenichi Sakamoto, Claudia G. Liberini, Ling Wang, Adrien Stanley, Hale E. Egritag, Sofia M. Sanz, Claudia Lindtner, Mary A. Butera, Christoph Buettner

Mol Metab. 2023 Dec; 78: 101813. Published online 2023 Sep 29. doi: 10.1016/j.molmet.2023.101813

PMCID:: PMC10590866

Abstract Article PDF–2.5M

Select item 104069763.

PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

Miwa Hara, Wenjing Wu, Volha V. Malechka, Yusuke Takahashi, Jian-Xing Ma, Gennadiy Moiseyev

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112091. Published online 2023 Feb 8. doi: 10.1016/j.celrep.2023.112091

PMCID:: PMC10406976

Abstract Article PDF–2.1M

Select item 102332104.

Ablation of pigment epithelium-derived factor receptor (PEDF-R/Pnpla2) causes photoreceptor degeneration

Alexandra Bernardo-Colón, Lijin Dong, Mones Abu-Asab, Richard S. Brush, Martin-Paul Agbaga, S. Patricia Becerra

J Lipid Res. 2023 May; 64(5): 100358. Published online 2023 Mar 17. doi: 10.1016/j.jlr.2023.100358

PMCID:: PMC10233210

Abstract Article PDF–3.4M

Select item 98711975.

N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage

Jiesi Xu, Zhenglong Liu, Jianxin Zhang, Siyu Chen, Wei Wang, Xuefan Zhao, Mei Zhen, Xun Huang

Diabetes. 2023 Feb; 72(2): 210–222. Published online 2022 Nov 8. doi: 10.2337/db22-0362

PMCID:: PMC9871197

Abstract Article PDF–67M

Select item 96188376.

Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency

Jide Oluwadare, Ainara G. Cabodevilla, Ni-Huiping Son, Yunying Hu, Adam E. Mullick, Michael Verano, Jose O. Alemán, Ravichandran Ramasamy, Ira J. Goldberg

J Lipid Res. 2022 Nov; 63(11): 100274. Published online 2022 Sep 15. doi: 10.1016/j.jlr.2022.100274

PMCID:: PMC9618837

Abstract Article PDF–4.7M

Select item 95611777.

Chronic intake of high dietary sucrose induces sexually dimorphic metabolic adaptations in mouse liver and adipose tissue

Erin J. Stephenson, Amanda S. Stayton, Aarti Sethuraman, Prahlad K. Rao, Alice Meyer, Charles Klazer Gomes, Molly C. Mulcahy, Liam McAllan, Michelle A. Puchowicz, Joseph F. Pierre, Dave Bridges, Joan C. Han

Nat Commun. 2022; 13: 6062. Published online 2022 Oct 13. doi: 10.1038/s41467-022-33840-6

PMCID:: PMC9561177

Abstract Article PDF–4.8M

Select item 89089928.

Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo

Madeleine Goeritzer, Stefanie Schlager, Katharina B. Kuentzel, Nemanja Vujić, Melanie Korbelius, Silvia Rainer, Dagmar Kolb, Marion Mussbacher, Manuel Salzmann, Waltraud C. Schrottmaier, Alice Assinger, Axel Schlagenhauf, Corina T. Madreiter-Sokolowski, Sandra Blass, Thomas O. Eichmann, Wolfgang F. Graier, Dagmar Kratky

Cells. 2022 Mar; 11(5): 850. Published online 2022 Mar 1. doi: 10.3390/cells11050850

PMCID:: PMC8908992

Abstract Article PDF–2.4M

Select item 88994129.

Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance

Alicia R. Romero, Andre Mu, Janelle S. Ayres

iScience. 2022 Mar 18; 25(3): 103941. Published online 2022 Feb 17. doi: 10.1016/j.isci.2022.103941

PMCID:: PMC8899412

Abstract Article PDF–5.3M

Select item 818119810.

Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice

Supreet Kaur, Christopher Auger, Dalia Barayan, Priyal Shah, Anna Matveev, Carly M. Knuth, Thurl E. Harris, Marc G. Jeschke

Clin Transl Med. 2021 Jun; 11(6): e417. Published online 2021 Jun 6. doi: 10.1002/ctm2.417

PMCID:: PMC8181198

Abstract Article PDF–4.2M

Select item 761386711.

Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis

Melanie Korbelius, Nemanja Vujić, Katharina B. Kuentzel, Sascha Obrowsky, Silvia Rainer, Guenter Haemmerle, Thomas Rülicke, Dagmar Kratky

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2022 Nov 30.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Apr 1; 1867(4): 159121. Published online 2022 Feb 9. doi: 10.1016/j.bbalip.2022.159121

PMCID:: PMC7613867

Abstract Article PDF–3.1M

Select item 711825212.

Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice

Veronika Paluchova, Marina Oseeva, Marie Brezinova, Tomas Cajka, Kristina Bardova, Katerina Adamcova, Petr Zacek, Kristyna Brejchova, Laurence Balas, Hana Chodounska, Eva Kudova, Renate Schreiber, Rudolf Zechner, Thierry Durand, Martin Rossmeisl, Nada A. Abumrad, Jan Kopecky, Ondrej Kuda

Diabetes. 2020 Mar; 69(3): 300–312. Published online 2020 Dec 5. doi: 10.2337/db19-0494

PMCID:: PMC7118252

Abstract Article PDF–1.7M

Select item 651807613.

A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice

Camille Attané, Marie-Line Peyot, Roxane Lussier, Pegah Poursharifi, Shangang Zhao, Dongwei Zhang, Johane Morin, Marco Pineda, Shupei Wang, Olivier Dumortier, Neil B. Ruderman, Grant A. Mitchell, Brigitte Simons, S. R. Murthy Madiraju, Erik Joly, Marc Prentki

Diabetologia. 2016; 59(12): 2654–2663. Published online 2016 Sep 27. doi: 10.1007/s00125-016-4105-2

PMCID:: PMC6518076

Abstract Article PDF–777K

Select item 512977114.

Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue

Rebecca E. K. MacPherson, Steven M. Dragos, Sofhia Ramos, Charles Sutton, Scott Frendo-Cumbo, Laura Castellani, Matthew J. Watt, Christopher G. R. Perry, David M. Mutch, David C. Wright

Am J Physiol Cell Physiol. 2016 Aug 1; 311(2): C269–C276. Published online 2016 Jun 29. doi: 10.1152/ajpcell.00126.2016

PMCID:: PMC5129771

Abstract Article

Select item 465321615.

Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity

Renate Schreiber, Peter Hofer, Ulrike Taschler, Peter J. Voshol, Gerald N. Rechberger, Petra Kotzbeck, Doris Jaeger, Karina Preiss-Landl, Caleb C. Lord, J. Mark Brown, Guenter Haemmerle, Robert Zimmermann, Antonio Vidal-Puig, Rudolf Zechner

Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45): 13850–13855. Published online 2015 Oct 27. doi: 10.1073/pnas.1516004112

PMCID:: PMC4653216

Abstract Article PDF–1.0M

Select item 461713016.

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation

Emilio P. Mottillo, Priya Balasubramanian, Yun-Hee Lee, Changren Weng, Erin E. Kershaw, James G. Granneman

J Lipid Res. 2014 Nov; 55(11): 2276–2286. doi: 10.1194/jlr.M050005

PMCID:: PMC4617130

Abstract Article PDF–1.5M

Select item 459476317.

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

Stefanie Schlager, Madeleine Goeritzer, Katharina Jandl, Robert Frei, Nemanja Vujic, Dagmar Kolb, Heimo Strohmaier, Juliane Dorow, Thomas O. Eichmann, Angelika Rosenberger, Albert Wölfler, Achim Lass, Erin E. Kershaw, Uta Ceglarek, Andrea Dichlberger, Akos Heinemann, Dagmar Kratky

J Leukoc Biol. 2015 Nov; 98(5): 837–850. Published online 2015 Jun 24. doi: 10.1189/jlb.3A0515-206R

PMCID:: PMC4594763

Abstract Article

Select item 458882118.

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice

Gabriele Schoiswohl, Maja Stefanovic-Racic, Marie N. Menke, Rachel C. Wills, Beth A. Surlow, Mahesh K. Basantani, Mitch T. Sitnick, Lingzhi Cai, Cynthia F. Yazbeck, Donna B. Stolz, Thomas Pulinilkunnil, Robert M. O'Doherty, Erin E. Kershaw

Endocrinology. 2015 Oct; 156(10): 3610–3624. Published online 2015 Jul 21. doi: 10.1210/en.2015-1322

PMCID:: PMC4588821

Abstract Article

Select item 458301419.

Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate

Anna Foryst-Ludwig, Michael C. Kreissl, Verena Benz, Sarah Brix, Elia Smeir, Zsofia Ban, Elżbieta Januszewicz, Janek Salatzki, Jana Grune, Anne-Kathrin Schwanstecher, Annelie Blumrich, Andreas Schirbel, Robert Klopfleisch, Michael Rothe, Katharina Blume, Martin Halle, Bernd Wolfarth, Erin E. Kershaw, Ulrich Kintscher

J Biol Chem. 2015 Sep 25; 290(39): 23603–23615. Published online 2015 Aug 10. doi: 10.1074/jbc.M115.645341

PMCID:: PMC4583014

Abstract Article PDF–3.1M

Select item 450682520.

Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics

Margarida Coelho, Patricia Nunes, Vera M. Mendes, Bruno Manadas, Arend Heerschap, John G. Jones

J Diabetes Res. 2015; 2015: 542029. Published online 2015 Jul 5. doi: 10.1155/2015/542029

PMCID:: PMC4506825

Abstract Article PDF–638K

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PMC Links for Gene (Select 66853) (154)
PMC
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C-like [M...
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C-like [Macaca nemestrina]
gi|1381416518|ref|XP_024649521.1|

Protein
Homo sapiens oligodendrocytic myelin paranodal and inner loop protein (OPALIN), ...
Homo sapiens oligodendrocytic myelin paranodal and inner loop protein (OPALIN), transcript variant 2, mRNA
gi|547235235|ref|NM_001040102.2|

Nucleotide

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