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Select item 83638351.

Smurf2 exerts neuroprotective effects on cerebral ischemic injury

Haibin Liu, Shengtao Sun, Bing Liu

J Biol Chem. 2021 Aug; 297(2): 100537. Published online 2021 Mar 12. doi: 10.1016/j.jbc.2021.100537

PMCID:: PMC8363835

Abstract Article PDF–4.2M

Select item 72758192.

The Effects of WW2/WW3 Domains of Smurf2 Molecule on CD4⁺CD25⁺/CD4⁺ Proportion in Spleen of 4T1 Tumor Bearing BALB/c Mice

Hani Mosayebzadeh Roshan, Seyed-Hosein Abtahi-Eivary, Hassan Shojaee-Mend, Alireza Mohammadzadeh, Zahra Bahari Sani

Iran Biomed J. 2020 Jul; 24(4): 214–219. Published online 2020 Feb 10. doi: 10.29252/ibj.24.4.214

PMCID:: PMC7275819

Abstract Article PDF–909K

Select item 59688463.

Generation of Smurf2 Conditional Knockout Mice

Yi Tang, Liu-Ya Tang, Xuan Xu, Cuiling Li, Chuxia Deng, Ying E. Zhang

Int J Biol Sci. 2018; 14(5): 542–548. Published online 2018 Apr 5. doi: 10.7150/ijbs.24303

PMCID:: PMC5968846

Abstract Article PDF–1.1M

Select item 52490614.

A Circulating microRNA Signature Predicts Age-Based Development of Lymphoma

Afshin Beheshti, Charles Vanderburg, J. Tyson McDonald, Charusheila Ramkumar, Tatenda Kadungure, Hong Zhang, Ronald B. Gartenhaus, Andrew M. Evens

PLoS One. 2017; 12(1): e0170521. Published online 2017 Jan 20. doi: 10.1371/journal.pone.0170521

PMCID:: PMC5249061

Abstract Article PDF–2.4M

Select item 47294895.

Skeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient Chondrocytes

Henry Huang, Eric S. Veien, Hong Zhang, David C. Ayers, Jie Song

PLoS One. 2016; 11(1): e0148088. Published online 2016 Jan 27. doi: 10.1371/journal.pone.0148088

PMCID:: PMC4729489

Abstract Article PDF–5.9M

Select item 40325996.

Smurf2 regulates hematopoietic stem cell self-renewal and aging

Charusheila Ramkumar, Yahui Kong, Sally E Trabucco, Rachel M Gerstein, Hong Zhang

Aging Cell. 2014 Jun; 13(3): 478–486. Published online 2014 Feb 4. doi: 10.1111/acel.12195

PMCID:: PMC4032599

Abstract Article PDF–363K

Select item 97653137.

Smurf2 Regulates Inflammation and Collagen Processing in Cutaneous Wound Healing through Transforming Growth Factor-β/Smad3 Signaling

Christina H. Stuelten, Nicolas Melis, Bhagawat Subramanian, Yi Tang, Megan Kimicata, John P. Fisher, Roberto Weigert, Ying E. Zhang

Am J Pathol. 2022 Dec; 192(12): 1699–1711. doi: 10.1016/j.ajpath.2022.08.002

PMCID:: PMC9765313

Abstract Article PDF–5.7M

Select item 90928368.

Inhibition of ChREBP ubiquitination via the ROS/Akt-dependent downregulation of Smurf2 contributes to lysophosphatidic acid-induced fibrosis in renal mesangial cells

Donghee Kim, Ga-Young Nam, Eunhui Seo, Hee-Sook Jun

J Biomed Sci. 2022; 29: 31. Published online 2022 May 10. doi: 10.1186/s12929-022-00814-1

PMCID:: PMC9092836

Abstract Article PDF–3.7M

Select item 86500449.

MicroRNA‐411‐3p inhibits bleomycin‐induced skin fibrosis by regulating transforming growth factor‐β/Smad ubiquitin regulatory factor‐2 signalling

Ziyan Zhang, Xuemin Gao, Yang He, Yumeng Kang, Fuyu Jin, Yaqian Li, Tian Li, Zhongqiu Wei, Shifeng Li, Wenchen Cai, Na Mao, Shan Wang, Heliang Liu, Fang Yang, Hong Xu, Jie Yang

J Cell Mol Med. 2021 Dec; 25(24): 11290–11299. Published online 2021 Nov 15. doi: 10.1111/jcmm.17055

PMCID:: PMC8650044

Abstract Article PDF–1.7M

Select item 658016110.

The HECT ubiquitin E3 ligase Smurf2 degrades μ-opioid receptor 1 in the ubiquitin-proteasome system in lung epithelial cells

Su Dong, Jia Liu, Lian Li, Heather Wang, Haichun Ma, Yutong Zhao, Jing Zhao

Am J Physiol Cell Physiol. 2019 May 1; 316(5): C632–C640. Published online 2019 Feb 13. doi: 10.1152/ajpcell.00443.2018

PMCID:: PMC6580161

Abstract Article

Select item 380110411.

Smurf2 suppresses B-cell proliferation and lymphomagenesis by mediating ubiquitination and degradation of YY1

Charusheila Ramkumar, Hang Cui, Yahui Kong, Stephen N. Jones, Rachel M. Gerstein, Hong Zhang

Nat Commun. Author manuscript; available in PMC 2013 Oct 21.

Published in final edited form as: Nat Commun. 2013; 4: 2598. doi: 10.1038/ncomms3598

PMCID:: PMC3801104

Abstract Article PDF–2.4M

Select item 532173712.

SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts

Zhan Xu, Matthew B. Greenblatt, Guang Yan, Heng Feng, Jun Sun, Sutada Lotinun, Nicholas Brady, Roland Baron, Laurie H. Glimcher, Weiguo Zou

Nat Commun. 2017; 8: 14570. Published online 2017 Feb 20. doi: 10.1038/ncomms14570

PMCID:: PMC5321737

Abstract Article PDF–2.4M

Select item 436987713.

AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by smurf2 and deubiquitinating enzyme USP4

Li Xiao, Xiang Peng, Fuyou Liu, Chengyuan Tang, Chun Hu, Xiaoxuan Xu, Ming Wang, Ying Luo, Shikun Yang, Panai Song, Ping Xiao, Yashpal S Kanwar, Lin Sun

BMC Cell Biol. 2015; 16: 7. Published online 2015 Mar 6. doi: 10.1186/s12860-015-0055-7

PMCID:: PMC4369877

Abstract Article PDF–1.9M

Select item 436688114.

TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation

Jarod A. Zepp, Ling Wu, Wen Qian, Wenjun Ouyang, Mark Aronica, Serpil Erzurum, Xiaoxia Li

J Immunol. Author manuscript; available in PMC 2016 Mar 15.

Published in final edited form as: J Immunol. 2015 Mar 15; 194(6): 2826–2837. Published online 2015 Feb 13. doi: 10.4049/jimmunol.1402647

PMCID:: PMC4366881

Abstract Article PDF–2.6M

Select item 408044915.

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception

Shen Yue, Liu-Ya Tang, Ying Tang, Yi Tang, Qiu-Hong Shen, Jie Ding, Yan Chen, Zengdi Zhang, Ting-Ting Yu, Ying E Zhang, Steven Y Cheng

eLife. 2014; 3: e02555. Published online 2014 Jun 12. doi: 10.7554/eLife.02555

PMCID:: PMC4080449

Abstract Article PDF–4.0M

Select item 376345516.

Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone

V Khedgikar, P Kushwaha, J Gautam, A Verma, B Changkija, A Kumar, S Sharma, G K Nagar, D Singh, P K Trivedi, N S Sangwan, P R Mishra, R Trivedi

Cell Death Dis. 2013 Aug; 4(8): e778. Published online 2013 Aug 22. doi: 10.1038/cddis.2013.294

PMCID:: PMC3763455

Abstract Article PDF–5.3M

Select item 361663617.

Smurf2 regulates the senescence response and suppresses tumorigenesis in mice

Charusheila Ramkumar, Yahui Kong, Hang Cui, Suyang Hao, Stephen N. Jones, Rachel M. Gerstein, Hong Zhang

Cancer Res. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Cancer Res. 2012 Jun 1; 72(11): 2714–2719. Published online 2012 May 2. doi: 10.1158/0008-5472.CAN-11-3773

PMCID:: PMC3616636

Abstract Article PDF–2.9M

Select item 327465018.

A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20

Michael Blank, Yi Tang, Motozo Yamashita, Sandra S. Burkett, Steven Y. Cheng, Ying E. Zhang

Nat Med. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Nat Med. 2012 Feb; 18(2): 227–234. Published online 2012 Jan 8. doi: 10.1038/nm.2596

PMCID:: PMC3274650

Abstract Article PDF–3.6M

Select item 297390019.

Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

Nengyin Sheng, Zhihui Xie, Chen Wang, Ge Bai, Kejing Zhang, Qingqing Zhu, Jianguo Song, Francois Guillemot, Ye-Guang Chen, Anning Lin, Naihe Jing

Proc Natl Acad Sci U S A. 2010 Nov 2; 107(44): 18886–18891. Published online 2010 Oct 18. doi: 10.1073/pnas.1009244107

PMCID:: PMC2973900

Abstract Article PDF–958K

Select item 42325620.

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice

Hirotaka Fukasawa, Tatsuo Yamamoto, Akashi Togawa, Naro Ohashi, Yoshihide Fujigaki, Toshiaki Oda, Chiharu Uchida, Kyoko Kitagawa, Takayuki Hattori, Sayuri Suzuki, Masatoshi Kitagawa, Akira Hishida

Proc Natl Acad Sci U S A. 2004 Jun 8; 101(23): 8687–8692. Published online 2004 Jun 1. doi: 10.1073/pnas.0400035101