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Select item 61007661.

Multi-Pronged Interactions Underlie Inhibition of α-Synuclein Aggregation by β-Synuclein

Jonathan K. Williams, Xue Yang, Tamr B. Atieh, Michael P. Olson, Sagar D. Khare, Jean Baum

J Mol Biol. Author manuscript; available in PMC 2019 Aug 3.

Published in final edited form as: J Mol Biol. 2018 Aug 3; 430(16): 2360–2371. Published online 2018 May 18. doi: 10.1016/j.jmb.2018.05.024

PMCID:: PMC6100766

Abstract Article PDF–916K

Select item 56250652.

A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues

Gina M. Moriarty, Michael P. Olson, Tamr B. Atieh, Maria K. Janowska, Sagar D. Khare, Jean Baum

J Biol Chem. 2017 Sep 29; 292(39): 16368–16379. Published online 2017 Jul 14. doi: 10.1074/jbc.M117.780528

PMCID:: PMC5625065

Abstract Article PDF–2.4M

Select item 48153003.

The loss of inhibitory C‐terminal conformations in disease associated P123H β‐synuclein

Maria K. Janowska, Jean Baum

Protein Sci. 2016 Jan; 25(1): 286–294. Published online 2015 Sep 21. doi: 10.1002/pro.2798

PMCID:: PMC4815300

Abstract Article PDF–1.3M

Select item 29922884.

Human β-Synuclein Rendered Fibrillogenic by Designed Mutations

Shahin Zibaee, Graham Fraser, Ross Jakes, David Owen, Louise C. Serpell, R. Anthony Crowther, Michel Goedert

J Biol Chem. 2010 Dec 3; 285(49): 38555–38567. Published online 2010 Sep 10. doi: 10.1074/jbc.M110.160721

PMCID:: PMC2992288

Abstract Article PDF–5.0M

Select item 105788945.

Plasma β‐synuclein, GFAP, and neurofilaments in patients with malignant gliomas undergoing surgical and adjuvant therapy

Samir Abu‐Rumeileh, Lorenzo Barba, Matthias Bache, Steffen Halbgebauer, Patrick Oeckl, Petra Steinacker, Antje Güttler, Jacqueline Keßler, Jörg Illert, Christian Strauss, Dirk Vordermark, Markus Otto

Ann Clin Transl Neurol. 2023 Oct; 10(10): 1924–1930. Published online 2023 Aug 23. doi: 10.1002/acn3.51878

PMCID:: PMC10578894

Abstract Article PDF–646K

Select item 59113436.

Significant Changes in Plasma Alpha-Synuclein and Beta-Synuclein Levels in Male Children with Autism Spectrum Disorder

Wilaiwan Sriwimol, Pornprot Limprasert

Biomed Res Int. 2018; 2018: 4503871. Published online 2018 Apr 8. doi: 10.1155/2018/4503871

PMCID:: PMC5911343

Abstract Article PDF–858K

Select item 42459787.

A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein

Jane R. Allison, Robert C. Rivers, John C. Christodoulou, Michele Vendruscolo, Christopher M. Dobson

Biochemistry. 2014 Nov 25; 53(46): 7170–7183. Published online 2014 Oct 28. doi: 10.1021/bi5009326

PMCID:: PMC4245978

Abstract Article PDF–4.1M

Select item 36326088.

Molecular Ageing of Alpha- and Beta-Synucleins: Protein Damage and Repair Mechanisms

Vasanthy Vigneswara, Simon Cass, Declan Wayne, Edward L. Bolt, David E. Ray, Wayne G. Carter

PLoS One. 2013; 8(4): e61442. Published online 2013 Apr 22. doi: 10.1371/journal.pone.0061442

PMCID:: PMC3632608

Abstract Article PDF–7.3M

Select item 35850729.

In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells

Ulf Dettmer, Andrew J. Newman, Eric S. Luth, Tim Bartels, Dennis Selkoe

J Biol Chem. 2013 Mar 1; 288(9): 6371–6385. Published online 2013 Jan 14. doi: 10.1074/jbc.M112.403311

PMCID:: PMC3585072

Abstract Article PDF–3.0M

Select item 304623910.

Transcriptional Regulation of the Beta-Synuclein 5′-Promoter Metal Response Element by Metal Transcription Factor-1

Patrick C. McHugh, Josephine A. Wright, David R. Brown

PLoS One. 2011; 6(2): e17354. Published online 2011 Feb 28. doi: 10.1371/journal.pone.0017354

PMCID:: PMC3046239

Abstract Article PDF–283K

Select item 297809711.

Inhibiting α-Synuclein Oligomerization by Stable Cell-Penetrating β-Synuclein Fragments Recovers Phenotype of Parkinson's Disease Model Flies

Ronit Shaltiel-Karyo, Moran Frenkel-Pinter, Nirit Egoz-Matia, Anat Frydman-Marom, Deborah E. Shalev, Daniel Segal, Ehud Gazit

PLoS One. 2010; 5(11): e13863. Published online 2010 Nov 10. doi: 10.1371/journal.pone.0013863

PMCID:: PMC2978097

Abstract Article PDF–1.9M

Select item 232727612.

Molecular determinants of the aggregation behavior of α- and β-synuclein

Robert C. Rivers, Janet R. Kumita, Gian Gaetano Tartaglia, Matthew M. Dedmon, Amol Pawar, Michele Vendruscolo, Christopher M. Dobson, John Christodoulou

Protein Sci. 2008 May; 17(5): 887–898. doi: 10.1110/ps.073181508

PMCID:: PMC2327276

Abstract Article PDF–703K

Select item 224251513.

Secondary structure and dynamics of micelle bound β- and γ-synuclein

Yoon-hui Sung, David Eliezer

Protein Sci. 2006 May; 15(5): 1162–1174. doi: 10.1110/ps.051803606

PMCID:: PMC2242515

Abstract Article PDF–625K

Select item 197817114.

Beta-synuclein gene variants and Parkinson’s disease: A preliminary case-control study

Laura Brighina, Njide U. Okubadejo, Nicole K. Schneider, Timothy G. Lesnick, Mariza de Andrade, Julie M. Cunningham, Matthew J. Farrer, Sarah J. Lincoln, Walter A. Rocca, Demetrius M. Maraganore

Neurosci Lett. Author manuscript; available in PMC 2008 Jun 15.

Published in final edited form as: Neurosci Lett. 2007 Jun 15; 420(3): 229–234. Published online 2007 May 21. doi: 10.1016/j.neulet.2007.05.021

PMCID:: PMC1978171

Abstract Article PDF–237K

Select item 1068460715.

Serum β-synuclein, neurofilament light chain and glial fibrillary acidic protein as prognostic biomarkers in moderate-to-severe acute ischemic stroke

Lorenzo Barba, Christoph Vollmuth, Samir Abu-Rumeileh, Steffen Halbgebauer, Patrick Oeckl, Petra Steinacker, Alexander M. Kollikowski, Cara Schultz, Judith Wolf, Mirko Pham, Michael K. Schuhmann, Peter U. Heuschmann, Karl Georg Haeusler, Guido Stoll, Hermann Neugebauer, Markus Otto

Sci Rep. 2023; 13: 20941. Published online 2023 Nov 28. doi: 10.1038/s41598-023-47765-7

PMCID:: PMC10684607

Abstract Article PDF–1.5M

Select item 295225016.

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

Jobin Varkey, Jose Mario Isas, Naoko Mizuno, Martin Borch Jensen, Vikram Kjøller Bhatia, Christine C. Jao, Jitka Petrlova, John C. Voss, Dimitrios G. Stamou, Alasdair C. Steven, Ralf Langen

J Biol Chem. 2010 Oct 15; 285(42): 32486–32493. Published online 2010 Aug 6. doi: 10.1074/jbc.M110.139576

PMCID:: PMC2952250

Abstract Article PDF–3.1M

Select item 209413417.

Residual structure, backbone dynamics, and interactions within the synuclein family

Yoon-hui Sung, David Eliezer

J Mol Biol. Author manuscript; available in PMC 2008 Sep 21.

Published in final edited form as: J Mol Biol. 2007 Sep 21; 372(3): 689–707. Published online 2007 Jul 17. doi: 10.1016/j.jmb.2007.07.008

PMCID:: PMC2094134

Abstract Article PDF–1.3M

Select item 180853918.

ß-Synuclein gene alterations in dementia with Lewy bodies

H. Ohtake, P. Limprasert, Y. Fan, O. Onodera, A. Kakita, H. Takahashi, L.T. Bonner, D.W. Tsuang, I.V.J. Murray, V.M.-Y. Lee, J.Q. Trojanowski, A. Ishikawa, J. Idezuka, M. Murata, T. Toda, T.D. Bird, J.B. Leverenz, S. Tsuji, A.R. La Spada

Neurology. Author manuscript; available in PMC 2007 Mar 4.

Published in final edited form as: Neurology. 2004 Sep 14; 63(5): 805–811. doi: 10.1212/01.wnl.0000139870.14385.3c

PMCID:: PMC1808539

Abstract Article PDF–427K

Select item 121835319.

Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC.

P H Jensen, P Hojrup, H Hager, M S Nielsen, L Jacobsen, O F Olesen, J Gliemann, R Jakes

Biochem J. 1997 Apr 15; 323(Pt 2): 539–546. doi: 10.1042/bj3230539

PMCID:: PMC1218353

Summary PDF–392K

Select item 354690720.

Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H ß-synuclein

Akio Sekigawa, Masayo Fujita, Kazunari Sekiyama, Yoshiki Takamatsu, Taku Hatano, Edward Rockenstein, Albert R La Spada, Eliezer Masliah, Makoto Hashimoto

Mol Brain. 2012; 5: 34. Published online 2012 Sep 26. doi: 10.1186/1756-6606-5-34

PMCID:: PMC3546907

Abstract Article PDF–2.6M

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PMC Links for Gene (Select 6620) (36)
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Partial duplication of the long arm of chromosome 8
Partial duplication of the long arm of chromosome 8

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ND5 [Arctodus simus]
ND5 [Arctodus simus]
Gene ID:6740960

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