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Select item 100278301.

Sialoadhesin (CD169/Siglec-1) is an extended molecule that escapes inhibitory cis-interactions and synergizes with other macrophage receptors to promote phagocytosis

Mariliis Klaas, Stuart Dubock, David J. P. Ferguson, Paul R. Crocker

Glycoconj J. 2023; 40(2): 213–223. Published online 2023 Feb 4. doi: 10.1007/s10719-022-10097-1

PMCID:: PMC10027830

Abstract Article PDF–2.2M

Select item 90715682.

Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response

Butsabong Lerkvaleekul, Saskia R Veldkamp, M Marlot van der Wal, Ellen J H Schatorjé, Sylvia S M Kamphuis, J Merlijn van den Berg, Petra C E Hissink Muller, Wineke Armbrust, Sebastiaan J Vastert, Judith Wienke, Marc H A Jansen, Annet van Royen-Kerkhof, Femke van Wijk

Rheumatology (Oxford) 2022 May; 61(5): 2144–2155. Published online 2021 Aug 13. doi: 10.1093/rheumatology/keab601

PMCID:: PMC9071568

Abstract Article PDF–896K

Select item 88600733.

SIGLEC1 enables straightforward assessment of type I interferon activity in idiopathic inflammatory myopathies

Manuel Graf, Sae Lim von Stuckrad, Akinori Uruha, Jens Klotsche, Lydia Zorn-Pauly, Nadine Unterwalder, Thomas Buttgereit, Martin Krusche, Christian Meisel, Gerd R Burmester, Falk Hiepe, Robert Biesen, Tilmann Kallinich, Werner Stenzel, Udo Schneider, Thomas Rose

RMD Open. 2022; 8(1): e001934. Published online 2022 Feb 17. doi: 10.1136/rmdopen-2021-001934

PMCID:: PMC8860073

Abstract Article PDF–907K

Select item 88069654.

Prognostic value of CD169-positive macrophages in various tumors: a meta-analysis

Weihao Kong, Meng Wei, Rongqiang Liu, Jianlin Zhang, Xingyu Wang

Bioengineered. 2021; 12(1): 8505–8514. Published online 2021 Oct 22. doi: 10.1080/21655979.2021.1985857

PMCID:: PMC8806965

Abstract Article PDF–536K

Select item 82656675.

CyTOF Profiling of Zika and Dengue Virus-Infected Human Peripheral Blood Mononuclear Cells Identifies Phenotypic Signatures of Monotype Subsets and Upregulation of the Interferon-Inducible Protein CD169

Rafael Fenutria, Kevin Maringer, Uma Potla, Dabeiba Bernal-Rubio, Matthew J. Evans, Eva Harris, Adeeb H. Rahman, Ana Fernandez-Sesma, Irene Ramos

mSphere. 2021 May-Jun; 6(3): e00505-21. Published online 2021 Jun 23. doi: 10.1128/mSphere.00505-21

PMCID:: PMC8265667

Abstract Article PDF–3.7M

Select item 81194136.

SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of multiple sclerosis patients

Lennard Ostendorf, Philipp Dittert, Robert Biesen, Ankelien Duchow, Victoria Stiglbauer, Klemens Ruprecht, Judith Bellmann-Strobl, Dominik Seelow, Werner Stenzel, Raluca A. Niesner, Anja E. Hauser, Friedemann Paul, Helena Radbruch

Sci Rep. 2021; 11: 10299. Published online 2021 May 13. doi: 10.1038/s41598-021-89786-0

PMCID:: PMC8119413

Abstract Article PDF–1.9M

Select item 80235467.

CD169/SIGLEC1 is expressed on circulating monocytes in COVID-19 and expression levels are associated with disease severity

Jan-Moritz Doehn, Christoph Tabeling, Robert Biesen, Jacopo Saccomanno, Elena Madlung, Eva Pappe, Frieder Gabriel, Florian Kurth, Christian Meisel, Victor M. Corman, Leif G. Hanitsch, Sascha Treskatsch, Kathrin Heim, Miriam S. Stegemann, Christoph Ruwwe-Glösenkamp, Holger C. Müller-Redetzky, Alexander Uhrig, Rajan Somasundaram, Claudia Spies, Horst von Bernuth, Jörg Hofmann, Christian Drosten, Norbert Suttorp, Martin Witzenrath, Leif E. Sander, Ralf-Harto Hübner

Infection. 2021; 49(4): 757–762. Published online 2021 Apr 6. doi: 10.1007/s15010-021-01606-9

PMCID:: PMC8023546

Abstract Article PDF–650K

Select item 80140948.

Monocyte CD169 expression in COVID‐19 patients upon intensive care unit admission

Marine Ortillon, Remy Coudereau, Martin Cour, Thomas Rimmelé, Marine Godignon, Morgane Gossez, Hodane Yonis, Laurent Argaud, Anne‐Claire Lukaszewicz, Fabienne Venet, Guillaume Monneret

Cytometry A. 2021 May; 99(5): 466–471. Published online 2021 Feb 5. doi: 10.1002/cyto.a.24315

PMCID:: PMC8014094

Abstract Article PDF–886K

Select item 77173479.

Monocyte CD169 expression as a biomarker in the early diagnosis of COVID-19

Anne-Sophie Bedin, Alain Makinson, Marie-Christine Picot, Frank Mennechet, Fabrice Malergue, Amandine Pisoni, Esperance Nyiramigisha, Lise Montagnier, Karine Bollore, Ségolène Debiesse, David Morquin, Penelope Bourgoin, Nicolas Veyrenche, Constance Renault, Vincent Foulongne, Caroline Bret, Arnaud Bourdin, Vincent Le Moing, Philippe Van de Perre, Edouard Tuaillon

J Infect Dis. 2020 Nov 18 : jiaa724. Published online 2020 Nov 18. doi: 10.1093/infdis/jiaa724

Correction in:: J Infect Dis. 2022 Feb 15; 225(4): 744.

PMCID:: PMC7717347

Abstract PDF–646K

Select item 768479610.

SIGLEC1 (CD169) is a sensitive biomarker for the deterioration of the clinical course in childhood systemic lupus erythematosus

Sae Lim von Stuckrad, Jens Klotsche, Robert Biesen, Mareike Lieber, Julia Thumfart, Christian Meisel, Nadine Unterwalder, Tilmann Kallinich

Lupus. 2020 Dec; 29(14): 1914–1925. Published online 2020 Oct 20. doi: 10.1177/0961203320965699

PMCID:: PMC7684796

Abstract Article PDF–573K

Select item 765717411.

CD169‐positive macrophages in regional lymph nodes are associated with a favorable prognosis in patients with colorectal carcinoma

Koji Ohnishi, Yoshihiro Komohara, Yoichi Saito, Yuji Miyamoto, Masayuki Watanabe, Hideo Baba, Motohiro Takeya

Cancer Sci. 2013 Sep; 104(9): 1237–1244. Published online 2013 Jul 9. doi: 10.1111/cas.12212

PMCID:: PMC7657174

Abstract Article PDF–2.1M

Select item 698602412.

Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease

Atsushi Tanno, Naoya Fujino, Mitsuhiro Yamada, Hisatoshi Sugiura, Taizou Hirano, Rie Tanaka, Hirohito Sano, Satoshi Suzuki, Yoshinori Okada, Masakazu Ichinose

Respir Res. 2020; 21: 30. Published online 2020 Jan 28. doi: 10.1186/s12931-020-1297-2

PMCID:: PMC6986024

Abstract Article PDF–1.8M

Select item 681513613.

Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors

Nicolas Ruffin, Ester Gea-Mallorquí, Flavien Brouiller, Mabel Jouve, Aymeric Silvin, Peter See, Charles-Antoine Dutertre, Florent Ginhoux, Philippe Benaroch

Proc Natl Acad Sci U S A. 2019 Oct 22; 116(43): 21685–21693. Published online 2019 Oct 7. doi: 10.1073/pnas.1911007116

PMCID:: PMC6815136

Abstract Article PDF–1.9M

Select item 594759414.

Siglec‐1 inhibits RSV‐induced interferon gamma production by adult T cells in contrast to newborn T cells

Jop Jans, Wendy W.J. Unger, Marloes Vissers, Inge M.L. Ahout, Inge Schreurs, Arthur Wickenhagen, Ronald de Groot, Marien I. de Jonge, Gerben Ferwerda

Eur J Immunol. 2018 Apr; 48(4): 621–631. Published online 2018 Jan 18. doi: 10.1002/eji.201747161

PMCID:: PMC5947594

Abstract Article PDF–2.0M

Select item 565690715.

Reduced number of CD169⁺ macrophages in pre‐metastatic regional lymph nodes is associated with subsequent metastatic disease in an animal model and with poor outcome in prostate cancer patients

Kerstin Strömvall, Kristoffer Sundkvist, Börje Ljungberg, Sofia Halin Bergström, Anders Bergh

Prostate. 2017 Nov 1; 77(15): 1468–1477. Published online 2017 Sep 7. doi: 10.1002/pros.23407

PMCID:: PMC5656907

Abstract Article PDF–1.9M

Select item 564082616.

Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon

Hisashi Akiyama, Nora-Guadalupe Pina Ramirez, Gregory Gibson, Christopher Kline, Simon Watkins, Zandrea Ambrose, Suryaram Gummuluru

J Virol. 2017 Nov 1; 91(21): e00972-17. Prepublished online 2017 Aug 9. Published online 2017 Oct 13. doi: 10.1128/JVI.00972-17

PMCID:: PMC5640826

Abstract Article PDF–2.2M

Select item 537828417.

Possible functions of CD169‐positive sinus macrophages in lymph nodes in anti‐tumor immune responses

Yoshihiro Komohara, Koji Ohnishi, Motohiro Takeya

Cancer Sci. 2017 Mar; 108(3): 290–295. Published online 2017 Mar 7. doi: 10.1111/cas.13137

PMCID:: PMC5378284

Abstract Article PDF–1.2M

Select item 529834018.

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1

Jason E. Hammonds, Neal Beeman, Lingmei Ding, Sarah Takushi, Ashwanth C. Francis, Jaang-Jiun Wang, Gregory B. Melikyan, Paul Spearman

PLoS Pathog. 2017 Jan; 13(1): e1006181. Published online 2017 Jan 27. doi: 10.1371/journal.ppat.1006181

PMCID:: PMC5298340

Abstract Article PDF–3.2M

Select item 511577419.

The Clinical Significance of CD169-Positive Lymph Node Macrophage in Patients with Breast Cancer

Takuya Shiota, Yuko Miyasato, Koji Ohnishi, Mutsuko Yamamoto-Ibusuki, Yutaka Yamamoto, Hirotaka Iwase, Motohiro Takeya, Yoshihiro Komohara

PLoS One. 2016; 11(11): e0166680. Published online 2016 Nov 18. doi: 10.1371/journal.pone.0166680

PMCID:: PMC5115774

Abstract Article PDF–1.9M

Select item 498752520.

Identification of Siglec-1 null individuals infected with HIV-1

Javier Martinez-Picado, Paul J. McLaren, Itziar Erkizia, Maureen P. Martin, Susana Benet, Margalida Rotger, Judith Dalmau, Dan Ouchi, Steven M. Wolinsky, Sudhir Penugonda, Huldrych F. Günthard, Jacques Fellay, Mary Carrington, Nuria Izquierdo-Useros, Amalio Telenti

Nat Commun. 2016; 7: 12412. Published online 2016 Aug 11. doi: 10.1038/ncomms12412

PMCID:: PMC4987525

Abstract Article PDF–617K

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