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Select item 85893301.

PEPT1 is essential for the growth of pancreatic cancer cells: a viable drug target

Bradley K. Schniers, Devaraja Rajasekaran, Ksenija Korac, Tyler Sniegowski, Vadivel Ganapathy, Yangzom D. Bhutia

Biochem J. 2021 Oct 29; 478(20): 3757–3774. Prepublished online 2021 Sep 27. Published online 2021 Oct 21. doi: 10.1042/BCJ20210377

PMCID:: PMC8589330

Abstract Article PDF–21M

Select item 81442102.

Epigenetic regulation of intestinal peptide transporter PEPT1 as a potential strategy for colorectal cancer sensitization

Yanhong Wang, Jiaqi Wang, Lingrong Yang, Liqing Qiu, Yuhui Hua, Shixiu Wu, Su Zeng, Lushan Yu, Xiaoli Zheng

Cell Death Dis. 2021 Jun; 12(6): 532. Published online 2021 May 24. doi: 10.1038/s41419-021-03814-5

PMCID:: PMC8144210

Abstract Article PDF–2.5M

Select item 60584943.

Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy

Yuqian Du, Chutong Tian, Menglin Wang, Di Huang, Wei Wei, Yan Liu, Lin Li, Bingjun Sun, Longfa Kou, Qiming Kan, Kexin Liu, Cong Luo, Jin Sun, Zhonggui He

Drug Deliv. 2018; 25(1): 1403–1413. Published online 2018 Jun 12. doi: 10.1080/10717544.2018.1480675

PMCID:: PMC6058494

Abstract Article PDF–1.6M

Select item 57263734.

Regulation profile of the intestinal peptide transporter 1 (PepT1)

Chun-Yang Wang, Shu Liu, Xiao-Nv Xie, Zhi-Rong Tan

Drug Des Devel Ther. 2017; 11: 3511–3517. Published online 2017 Dec 8. doi: 10.2147/DDDT.S151725

PMCID:: PMC5726373

Abstract Article PDF–245K

Select item 47147435.

A new target ligand Ser–Glu for PEPT1-overexpressing cancer imaging

Tongcheng Dai, Na Li, Lingzhi Zhang, Yuanxing Zhang, Qin Liu

Int J Nanomedicine. 2016; 11: 203–212. Published online 2016 Jan 11. doi: 10.2147/IJN.S97207

PMCID:: PMC4714743

Abstract Article PDF–2.4M

Select item 46114556.

Hormonal regulation of dipeptide transporter (PepT1) in Caco-2 cells with normal and anoxia/reoxygenation management

Bing-Wei Sun, Xiao-Chen Zhao, Guang-Ji Wang, Ning Li, Jie-Shou Li

World J Gastroenterol. 2003 Apr 15; 9(4): 808–812. Published online 2003 Apr 15. doi: 10.3748/wjg.v9.i4.808

PMCID:: PMC4611455

Abstract Article PDF–180K

Select item 39485527.

Transcriptional and functional regulation of the intestinal peptide transporter PEPT1

Britta Spanier

J Physiol. 2014 Mar 1; 592(Pt 5): 871–879. Published online 2013 Sep 24. doi: 10.1113/jphysiol.2013.258889

PMCID:: PMC3948552

Abstract Article PDF–461K

Select item 29506918.

PepT1 mediates transport of the proinflammatory bacterial tripeptide l-Ala-γ-d-Glu-meso-DAP in intestinal epithelial cells

Guillaume Dalmasso, Hang Thi Thu Nguyen, Laetitia Charrier-Hisamuddin, Yutao Yan, Hamed Laroui, Benjamin Demoulin, Shanthi V. Sitaraman, Didier Merlin

Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3): G687–G696. Published online 2010 Jun 17. doi: 10.1152/ajpgi.00527.2009

PMCID:: PMC2950691

Abstract Article

Select item 29041119.

The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase

Myrtani Pieri, Helen C. Christian, Robert J. Wilkins, C. A. R. Boyd, David Meredith

Am J Physiol Gastrointest Liver Physiol. 2010 Jul; 299(1): G136–G143. Published online 2010 Apr 29. doi: 10.1152/ajpgi.00014.2010

PMCID:: PMC2904111

Abstract Article

Select item 286142410.

Mutagenesis and Cysteine Scanning of Transmembrane Domain 10 of the Human Dipeptide Transporter

Liya Xu, Ian S. Haworth, Ashutosh A. Kulkarni, Michael B. Bolger, Daryl L. Davies

Pharm Res. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Pharm Res. 2009 Oct; 26(10): 2358–2366. Published online 2009 Aug 14. doi: 10.1007/s11095-009-9952-9

PMCID:: PMC2861424

Abstract Article PDF–1.3M

Select item 286142111.

Ethanol Inhibits Functional Activity of the Human Intestinal Dipeptide Transporter hPepT1 Expressed in Xenopus Oocytes

Kaixun Li, Liya Xu, Ashutosh A. Kulkarni, Daya I. Perkins, Ian S. Haworth, Daryl L. Davies

Alcohol Clin Exp Res. Author manuscript; available in PMC 2010 Apr 29.

Published in final edited form as: Alcohol Clin Exp Res. 2008 May; 32(5): 777–784. Published online 2008 Mar 11. doi: 10.1111/j.1530-0277.2008.00636.x

PMCID:: PMC2861421

Abstract Article PDF–585K

Select item 223083412.

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

Dianne Walker, David T Thwaites, Nicholas L Simmons, Harry J Gilbert, Barry H Hirst

J Physiol. 1998 Mar 15; 507(Pt 3): 697–706. doi: 10.1111/j.1469-7793.1998.697bs.x

PMCID:: PMC2230834

Abstract Article PDF–1.2M

Select item 181779913.

Molecular interactions between dipeptides, drugs and the human intestinal H⁺–oligopeptide cotransporter hPEPT1

Monica Sala-Rabanal, Donald D F Loo, Bruce A Hirayama, Eric Turk, Ernest M Wright

J Physiol. 2006 Jul 1; 574(Pt 1): 149–166. Published online 2006 Apr 20. doi: 10.1113/jphysiol.2006.107904

PMCID:: PMC1817799

Abstract Article PDF–827K

Select item 146453514.

Computational modelling of H⁺-coupled peptide transport via human PEPT1

Megumi Irie, Tomohiro Terada, Toshiya Katsura, Satoshi Matsuoka, Ken-ichi Inui

J Physiol. 2005 Jun 1; 565(Pt 2): 429–439. Published online 2005 Mar 31. doi: 10.1113/jphysiol.2005.084582

PMCID:: PMC1464535

Abstract Article PDF–301K

Select item 50915415.

hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions.

D Merlin, A Steel, A T Gewirtz, M Si-Tahar, M A Hediger, J L Madara

J Clin Invest. 1998 Dec 1; 102(11): 2011–2018. doi: 10.1172/JCI4179

PMCID:: PMC509154

Summary PDF–294K

Select item 482169116.

Species Differences in the Pharmacokinetics of Cefadroxil as Determined in Wildtype and Humanized PepT1 Mice

Yongjun Hu, David E. Smith

Biochem Pharmacol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Biochem Pharmacol. 2016 May 1; 107: 81–90. Published online 2016 Mar 12. doi: 10.1016/j.bcp.2016.03.008

PMCID:: PMC4821691

Abstract Article PDF–1.4M

Select item 392950517.

Colonic miRNA Expression/Secretion, Regulated by Intestinal Epithelial PepT1, Plays an Important Role in Cell-to-Cell Communication during Colitis

Saravanan Ayyadurai, Moiz A. Charania, Bo Xiao, Emilie Viennois, Yuchen Zhang, Didier Merlin

PLoS One. 2014; 9(2): e87614. Published online 2014 Feb 19. doi: 10.1371/journal.pone.0087614

PMCID:: PMC3929505

Abstract Article PDF–7.0M

Select item 318684218.

The PepT1–NOD2 Signaling Pathway Aggravates Induced Colitis in Mice

Guillaume Dalmasso, Hang Thi Thu Nguyen, Sarah A. Ingersoll, Saravanan Ayyadurai, Hamed Laroui, Moiz A Charania, Yutao Yan, Shanthi V Sitaraman, Didier Merlin

Gastroenterology. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: Gastroenterology. 2011 Oct; 141(4): 1334–1345. Published online 2011 Jul 14. doi: 10.1053/j.gastro.2011.06.080