PMC Links for Gene (Select 6490) - PMC

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2019 Oct; 1867(10): 961–969. Published online 2019 Feb 2. doi: 10.1016/j.bbapap.2019.01.012

PMCID:: PMC6700743

Article PDF–2.0M

Select item 66771296.

Lysophospholipids induce Fibrillation of the Repeat domain of Pmel17 through intermediate core-shell structures

Jannik Nedergaard Pedersen, Zhiping Jiang, Gunna Christiansen, Jennifer C. Lee, Jan Skov Pedersen, Daniel E. Otzen

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2019 May; 1867(5): 519–528. Published online 2018 Nov 22. doi: 10.1016/j.bbapap.2018.11.007

PMCID:: PMC6677129

Article PDF–2.0M

Select item 56294337.

Polyfunctional response by ImmTAC (IMCgp100) redirected CD8⁺ and CD4⁺ T cells

Caroline Boudousquie, Giovanna Bossi, Jacob M. Hurst, Karolina A. Rygiel, Bent K. Jakobsen, Namir J. Hassan

Immunology. 2017 Nov; 152(3): 425–438. Published online 2017 Aug 2. doi: 10.1111/imm.12779

PMCID:: PMC5629433

Article PDF–1000K

Select item 48614638.

A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen

Valentina Bianchi, Anna Bulek, Anna Fuller, Angharad Lloyd, Meriem Attaf, Pierre J. Rizkallah, Garry Dolton, Andrew K. Sewell, David K. Cole

J Biol Chem. 2016 Apr 22; 291(17): 8951–8959. Published online 2016 Feb 25. doi: 10.1074/jbc.M115.707414

PMCID:: PMC4861463

Article PDF–1.8M

Select item 47513989.

The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation

Tina Ho, Brenda Watt, Lynn A. Spruce, Steven H. Seeholzer, Michael S. Marks

J Biol Chem. 2016 Feb 12; 291(7): 3595–3612. Published online 2015 Dec 22. doi: 10.1074/jbc.M115.692442

PMCID:: PMC4751398

Article PDF–3.3M

Select item 462977910.

Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes

Julio C. Valencia, Hidenori Watabe, An Chi, Francois Rouzaud, Kevin G. Chen, Wilfred D. Vieira, Kaoruko Takahashi, Yuji Yamaguchi, Werner Berens, Kunio Nagashima, Jeffrey Shabanowitz, Donald F. Hunt, Ettore Appella, Vincent J. Hearing

J Cell Sci. Author manuscript; available in PMC 2015 Nov 2.

Published in final edited form as: J Cell Sci. 2006 Mar 15; 119(0 6): 1080–1091. Published online 2006 Feb 21. doi: 10.1242/jcs.02804

PMCID:: PMC4629779

Article PDF–1.2M

Select item 425890311.

Lysophospholipid-containing Membranes Modulate the Fibril Formation of the Repeat Domain of a Human Functional Amyloid, Pmel17

Zhiping Jiang, Jennifer C. Lee

J Mol Biol. Author manuscript; available in PMC 2015 Dec 12.

Published in final edited form as: J Mol Biol. 2014 Dec 12; 426(24): 4074–4086. Published online 2014 Oct 14. doi: 10.1016/j.jmb.2014.10.009

PMCID:: PMC4258903

Article PDF–2.7M

Select item 360850512.

Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils

Ralf M. Leonhardt, Nathalie Vigneron, Jia Shee Hee, Morven Graham, Peter Cresswell

Mol Biol Cell. 2013 Apr 1; 24(7): 964–981. doi: 10.1091/mbc.E12-10-0742

PMCID:: PMC3608505

Article PDF–22M

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The Melanosomal Protein PMEL17 as a Target for Antibody Drug Conjugate Therapy in Melanoma

Youjun Chen, Cecile Chalouni, Christine Tan, Robyn Clark, Rayna Venook, Rachana Ohri, Helga Raab, Ron Firestein, William Mallet, Paul Polakis

J Biol Chem. 2012 Jul 13; 287(29): 24082–24091. Published online 2012 May 21. doi: 10.1074/jbc.M112.361485

PMCID:: PMC3397835

Article PDF–3.1M

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Probing Fibril Dissolution of the Repeat Domain of a Functional Amyloid, Pmel17, on the Microscopic and Residue Level

Ryan P. McGlinchey, James M. Gruschus, Attila Nagy, Jennifer C. Lee

Biochemistry. Author manuscript; available in PMC 2012 Dec 13.

Published in final edited form as: Biochemistry. 2011 Dec 13; 50(49): 10567–10569. Published online 2011 Nov 17. doi: 10.1021/bi201578h

PMCID:: PMC3232329

Article PDF–594K

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Mutations in or near the Transmembrane Domain Alter PMEL Amyloid Formation from Functional to Pathogenic

Brenda Watt, Danièle Tenza, Mark A. Lemmon, Susanne Kerje, Graça Raposo, Leif Andersson, Michael S. Marks

PLoS Genet. 2011 Sep; 7(9): e1002286. Published online 2011 Sep 15. doi: 10.1371/journal.pgen.1002286

PMCID:: PMC3174235

Article PDF–2.7M

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Proprotein Convertases Process Pmel17 during Secretion

Ralf M. Leonhardt, Nathalie Vigneron, Christoph Rahner, Peter Cresswell

J Biol Chem. 2011 Mar 18; 286(11): 9321–9337. Published online 2011 Jan 19. doi: 10.1074/jbc.M110.168088

PMCID:: PMC3059051

Article PDF–4.7M

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Endoplasmic Reticulum Export, Subcellular Distribution, and Fibril Formation by Pmel17 Require an Intact N-terminal Domain Junction

Ralf M. Leonhardt, Nathalie Vigneron, Christoph Rahner, Benoît J. Van den Eynde, Peter Cresswell

J Biol Chem. 2010 May 21; 285(21): 16166–16183. Published online 2010 Mar 15. doi: 10.1074/jbc.M109.097725

PMCID:: PMC2871485

Article PDF–9.8M

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The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding

Toshihiko Hoashi, Kunihiko Tamaki, Vincent J. Hearing

FASEB J. 2010 Mar; 24(3): 916–930. doi: 10.1096/fj.09-140921

PMCID:: PMC2830135

Article

Select item 279367419.

A Novel Splice Variant of Pmel17 Expressed by Human Melanocytes and Melanoma Cells Lacking Some of the Internal Repeats

Sarah E. Nichols, Dawn C. Harper, Joanne F. Berson, Michael S. Marks

J Invest Dermatol. Author manuscript; available in PMC 2009 Dec 15.

Published in final edited form as: J Invest Dermatol. 2003 Oct; 121(4): 821–830. doi: 10.1046/j.1523-1747.2003.12474.x

PMCID:: PMC2793674

Article PDF–1.8M

Select item 279098420.

N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils

Brenda Watt, Guillaume van Niel, Douglas M. Fowler, Ilse Hurbain, Kelvin C. Luk, Steven E. Stayrook, Mark A. Lemmon, Graça Raposo, James Shorter, Jeffery W. Kelly, Michael S. Marks

J Biol Chem. 2009 Dec 18; 284(51): 35543–35555. Published online 2009 Oct 19. doi: 10.1074/jbc.M109.047449