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Select item 106713541.

Role of ST6GAL1 in Thyroid Cancers: Insights from Tissue Analysis and Genomic Datasets

Ivana Gunjača, Benjamin Benzon, Nikolina Pleić, Mirjana Babić Leko, Valdi Pešutić Pisac, Ana Barić, Dean Kaličanin, Ante Punda, Ozren Polašek, Katarina Vukojević, Tatijana Zemunik

Int J Mol Sci. 2023 Nov; 24(22): 16334. Published online 2023 Nov 15. doi: 10.3390/ijms242216334

PMCID:: PMC10671354

Abstract Article PDF–1.5M

Select item 105600822.

Role of the ST6GAL1 sialyltransferase in regulating ovarian cancer cell metabolism

Robert B Jones, Austin D Silva, Katherine E Ankenbauer, Colleen M Britain, Asmi Chakraborty, Jamelle A Brown, Scott W Ballinger, Susan L Bellis

Glycobiology. 2023 Aug; 33(8): 626–636. Published online 2023 Jun 26. doi: 10.1093/glycob/cwad051

PMCID:: PMC10560082

Abstract Article PDF–1.3M

Select item 96632943.

Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness

Nitai C. Hait, Aparna Maiti, Rongrong Wu, Valerie L. Andersen, Chang-Chieh Hsu, Yun Wu, Digantkumar G. Chapla, Kazuaki Takabe, Michael E. Rusiniak, Wiam Bshara, Jianmin Zhang, Kelley W. Moremen, Joseph T. Y. Lau

Cancer Gene Ther. 2022; 29(11): 1662–1675. Published online 2022 Jun 8. doi: 10.1038/s41417-022-00485-y

PMCID:: PMC9663294

Abstract Article PDF–7.6M

Select item 95456094.

Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand‐foot syndrome

Katie Watts, Christopher Wills, Ayman Madi, Claire Palles, Timothy S. Maughan, Richard Kaplan, Nada A. Al‐Tassan, Rachel Kerr, David J. Kerr, Richard S. Houlston, Valentina Escott‐Price, Jeremy P. Cheadle

Int J Cancer. 2022 Sep 15; 151(6): 957–966. Published online 2022 May 10. doi: 10.1002/ijc.34046

PMCID:: PMC9545609

Abstract Article PDF–3.8M

Select item 92805265.

Extracellular ST6GAL1 regulates monocyte–macrophage development and survival

Michael E Rusiniak, Patrick R Punch, Nitai C Hait, Aparna Maiti, Robert T Burns, Digantkumar Chapla, Kelley W Moremen, Peng Zhao, Lance Wells, Karin Hoffmeister, Joseph T Y Lau

Glycobiology. 2022 Aug; 32(8): 701–711. Published online 2022 Jun 2. doi: 10.1093/glycob/cwac032

PMCID:: PMC9280526

Abstract Article PDF–1.3M

Select item 88576466.

Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer

Mary Smithson, Regina Irwin, Gregory Williams, Katie L. Alexander, Lesley E. Smythies, Marie Nearing, M. Chandler McLeod, Sameer Al Diffalha, Susan L. Bellis, Karin M. Hardiman

J Biol Chem. 2022 Mar; 298(3): 101594. Published online 2022 Jan 15. doi: 10.1016/j.jbc.2022.101594

PMCID:: PMC8857646

Abstract Article PDF–1.9M

Select item 81767737.

Regulation of ST6GAL1 sialyltransferase expression in cancer cells

Kaitlyn A Dorsett, Michael P Marciel, Jihye Hwang, Katherine E Ankenbauer, Nikita Bhalerao, Susan L Bellis

Glycobiology. 2021 May; 31(5): 530–539. Published online 2020 Dec 14. doi: 10.1093/glycob/cwaa110

PMCID:: PMC8176773

Abstract Article PDF–782K

Select item 79490658.

Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells

Colleen M. Britain, Nikita Bhalerao, Austin D. Silva, Asmi Chakraborty, Donald J. Buchsbaum, Michael R. Crowley, David K. Crossman, Yvonne J.K. Edwards, Susan L. Bellis

J Biol Chem. 2021 Jan-Jun; 296: 100034. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.014126

PMCID:: PMC7949065

Abstract Article PDF–3.2M

Select item 75490449.

Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover

Katie L. Alexander, Carolina A. Serrano, Asmi Chakraborty, Marie Nearing, Leona N. Council, Arnoldo Riquelme, Marcelo Garrido, Susan L. Bellis, Lesley E. Smythies, Phillip D. Smith

J Biol Chem. 2020 Oct 9; 295(41): 14153–14163. Published online 2020 Aug 6. doi: 10.1074/jbc.RA120.014887

PMCID:: PMC7549044

Abstract Article PDF–3.2M

Select item 752127510.

ST6Gal1 is up‐regulated and associated with aberrant IgA1 glycosylation in IgA nephropathy: An integrated analysis of the transcriptome

Youxia Liu, Fanghao Wang, Yaru Zhang, Junya Jia, Tiekun Yan

J Cell Mol Med. 2020 Sep; 24(18): 10493–10500. Published online 2020 Jul 17. doi: 10.1111/jcmm.15664

PMCID:: PMC7521275

Abstract Article PDF–654K

Select item 537778111.

The Glycosyltransferase ST6Gal-I Protects Tumor Cells against Serum Growth Factor Withdrawal by Enhancing Survival Signaling and Proliferative Potential

Colleen M. Britain, Kaitlyn A. Dorsett, Susan L. Bellis

J Biol Chem. 2017 Mar 17; 292(11): 4663–4673. Published online 2017 Jan 30. doi: 10.1074/jbc.M116.763862

PMCID:: PMC5377781

Abstract Article PDF–2.7M

Select item 532316212.

ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway

Anwen Wei, Bo Fan, Yujie Zhao, Han Zhang, Liping Wang, Xiao Yu, Qingmin Yuan, Deyong Yang, Shujing Wang

Oncotarget. 2016 Oct 4; 7(40): 65374–65388. Published online 2016 Aug 30. doi: 10.18632/oncotarget.11699

PMCID:: PMC5323162

Abstract Article PDF–13M

Select item 523952713.

ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway

Xixi Chen, Liping Wang, Yujie Zhao, Shiqi Yuan, Qiang Wu, Xiaoling Zhu, Bachir Niang, Shujing Wang, Jianing Zhang

Oncotarget. 2016 Aug 9; 7(32): 51955–51964. Published online 2016 Jun 21. doi: 10.18632/oncotarget.10192

PMCID:: PMC5239527

Abstract Article PDF–7.1M

Select item 516209014.

Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells

Xiaopeng Zhang, Chunchen Pan, Lei Zhou, Zhaogen Cai, Shufang Zhao, Donghong Yu

BMC Cancer. 2016; 16: 949. Published online 2016 Dec 16. doi: 10.1186/s12885-016-2981-y

PMCID:: PMC5162090

Abstract Article PDF–2.9M

Select item 454844615.

Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells

Yu-Chieh Wang, Jason W. Stein, Candace L. Lynch, Ha T. Tran, Chia-Yao Lee, Ronald Coleman, Adam Hatch, Victor G. Antontsev, Hun S. Chy, Carmel M. O’Brien, Shashi K. Murthy, Andrew L. Laslett, Suzanne E. Peterson, Jeanne F. Loring

Sci Rep. 2015; 5: 13317. Published online 2015 Aug 25. doi: 10.1038/srep13317