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Select item 111595101.

Enhanced SMYD3 expression is essential for the growth of breast cancer cells

Ryuji Hamamoto, Fabio Pittella Silva, Masataka Tsuge, Toshihiko Nishidate, Toyomasa Katagiri, Yusuke Nakamura, Yoichi Furukawa

Cancer Sci. 2006 Feb; 97(2): 113–118. Published online 2006 Jan 25. doi: 10.1111/j.1349-7006.2006.00146.x

PMCID:: PMC11159510

Abstract Article PDF–280K

Select item 111586912.

Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking

Haijian Wang, Yang Liu, Wen Tan, Yang Zhang, Naiqing Zhao, Yan Jiang, Chengzhao Lin, Bingtao Hao, Dan Zhao, Ji Qian, Daru Lu, Li Jin, Qingyi Wei, Dongxin Lin, Fuchu He

Cancer Sci. 2008 Apr; 99(4): 787–791. Published online 2008 Feb 21. doi: 10.1111/j.1349-7006.2008.00729.x

PMCID:: PMC11158691

Abstract Article PDF–101K

Select item 106880753.

The SMYD3-dependent H3K4me3 status of IGF2 intensifies local Th2 differentiation in CRSwNP via positive feedback

Lei Yu, Yi Wei, Tong Lu, Zhengqi Li, Shimin Lai, Yan Yan, Changhui Chen, Weiping Wen

Cell Commun Signal. 2023; 21: 345. Published online 2023 Nov 30. doi: 10.1186/s12964-023-01375-y

PMCID:: PMC10688075

Abstract Article PDF–4.4M

Select item 104077664.

SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck

Nupur Nigam, Benjamin Bernard, Samantha Sevilla, Sohyoung Kim, Mohd Saleem Dar, Daniel Tsai, Yvette Robbins, Kyunghee Burkitt, Cem Sievers, Clint T. Allen, Richard L. Bennett, Theophilus T. Tettey, Benjamin Carter, Lorenzo Rinaldi, Mark W. Lingen, Houssein Sater, Elijah F. Edmondson, Arfa Moshiri, Abbas Saeed, Hui Cheng, Xiaolin Luo, Kevin Brennan, Vishal Koparde, Chen Chen, Sudipto Das, Thorkell Andresson, Abdalla Abdelmaksoud, Madhavi Murali, Seiji Sakata, Kengo Takeuchi, Raj Chari, Yusuke Nakamura, Ravindra Uppaluri, John B. Sunwoo, Carter Van Waes, Jonathan D. Licht, Gordon L. Hager, Vassiliki Saloura

Cell Rep. Author manuscript; available in PMC 2023 Aug 8.

Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112823. Published online 2023 Jul 17. doi: 10.1016/j.celrep.2023.112823

PMCID:: PMC10407766

Abstract Article PDF–2.2M

Select item 102239395.

Histone lysine methyltransferase SMYD3 promotes oral squamous cell carcinoma tumorigenesis via H3K4me3-mediated HMGA2 transcription

Zongcheng Yang, Fen Liu, Zongkai Li, Nianping Liu, Xinfeng Yao, Yu Zhou, Liyu Zhang, Pan Jiang, Honghong Liu, Lingming Kong, Chuandong Lang, Xin Xu, Jihui Jia, Takahito Nakajima, Wenchao Gu, Lixin Zheng, Zhihong Zhang

Clin Epigenetics. 2023; 15: 92. Published online 2023 May 26. doi: 10.1186/s13148-023-01506-9

PMCID:: PMC10223939

Abstract Article PDF–12M

Select item 97956226.

SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells

Yang Yang, Rongfang Qiu, Siyu Zhao, Lin Shen, Bufu Tang, Qiaoyou Weng, Ziwei Xu, Liyun Zheng, Weiqian Chen, Gaofeng Shu, Yajie Wang, Zhongwei Zhao, Minjiang Chen, Jiansong Ji

BMC Biol. 2022; 20: 294. Published online 2022 Dec 27. doi: 10.1186/s12915-022-01499-6

PMCID:: PMC9795622

Abstract Article PDF–8.0M

Select item 82679387.

Mechanism of the Conformational Change of the Protein Methyltransferase SMYD3: A Molecular Dynamics Simulation Study

Jixue Sun, Zibin Li, Na Yang

Int J Mol Sci. 2021 Jul; 22(13): 7185. Published online 2021 Jul 2. doi: 10.3390/ijms22137185

PMCID:: PMC8267938

Abstract Article PDF–3.5M

Select item 79125098.

SMYD3: a regulator of epigenetic and signaling pathways in cancer

Benjamin J. Bernard, Nupur Nigam, Kyunghee Burkitt, Vassiliki Saloura

Clin Epigenetics. 2021; 13: 45. Published online 2021 Feb 26. doi: 10.1186/s13148-021-01021-9

PMCID:: PMC7912509

Abstract Article PDF–1.3M

Select item 73848479.

SMYD3 overexpression indicates poor prognosis and promotes cell proliferation, migration and invasion in non-small cell lung cancer

Jing Li, Lifang Zhao, Yunjian Pan, Xiao Ma, Li Liu, Wuzhang Wang, Wenjie You

Int J Oncol. 2020 Sep; 57(3): 756–766. Published online 2020 Jul 7. doi: 10.3892/ijo.2020.5095

PMCID:: PMC7384847

Abstract Article PDF–1.5M

Select item 704175810.

High expression of SMYD3 indicates poor survival outcome and promotes tumour progression through an IGF-1R/AKT/E2F-1 positive feedback loop in bladder cancer

Guoliang Wang, Yi Huang, Feilong Yang, Xiaojun Tian, Kun Wang, Li Liu, Yidong Fan, Xiaofeng Li, Luchao Li, Benkang Shi, Yichang Hao, Chuanyou Xia, Qingsheng Nie, Yue Xin, Zhenfeng Shi, Lulin Ma, Dawei Xu, Cheng Liu

Aging (Albany NY) 2020 Feb 15; 12(3): 2030–2048. Published online 2020 Feb 1. doi: 10.18632/aging.102718

PMCID:: PMC7041758

Abstract Article PDF–1.6M

Select item 702900411.

Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma

Mai Thanh Binh, Nghiem Xuan Hoan, Dao Phuong Giang, Hoang Van Tong, C.-Thomas Bock, Heiner Wedemeyer, Nguyen Linh Toan, Mai Hong Bang, Peter G. Kremsner, Christian G. Meyer, Le Huu Song, Thirumalaisamy P. Velavan

Sci Rep. 2020; 10: 2797. Published online 2020 Feb 18. doi: 10.1038/s41598-020-59667-z

PMCID:: PMC7029004

Abstract Article PDF–1.2M

Select item 600050412.

组蛋白甲基化酶SMYD3在肿瘤中的研究进展

Zhongguo Fei Ai Za Zhi. 2014 Sep 20; 17(9): 689–694. Chinese. doi: 10.3779/j.issn.1009-3419.2014.09.09

PMCID:: PMC6000504

Article PDF–867K

Select item 547659713.

SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression

Yun-Ju Chen, Cheng-Hui Tsai, Pin-Yu Wang, Shu-Chun Teng

Sci Rep. 2017; 7: 3842. Published online 2017 Jun 19. doi: 10.1038/s41598-017-03385-6

PMCID:: PMC5476597

Abstract Article PDF–4.2M

Select item 520701014.

SET and MYND Domain-Containing Protein 3 (SMYD3) Polymorphism as a Risk Factor for Susceptibility and Poor Prognosis in Ovarian Cancer

Ting-Ting Liu, Hui Xu, Wei-Ping Gao, Shu-Xiang Zhang, Xu-Hong Zhou, Juan Tang, Qiong-Na Liu

Med Sci Monit. 2016; 22: 5131–5140. Published online 2016 Dec 26. doi: 10.12659/MSM.898095

PMCID:: PMC5207010

Abstract Article PDF–715K

Select item 486148315.

Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase

Weiqi Fu, Nan Liu, Qi Qiao, Mingzhu Wang, Jinrong Min, Bing Zhu, Rui-Ming Xu, Na Yang

J Biol Chem. 2016 Apr 22; 291(17): 9173–9180. Published online 2016 Feb 29. doi: 10.1074/jbc.M115.709832

PMCID:: PMC4861483

Abstract Article PDF–1.7M

Select item 413919316.

The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production

Carol-Ann Eberle, Margarita Zayas, Alexey Stukalov, Andreas Pichlmair, Gualtiero Alvisi, André C. Müller, Keiryn L. Bennett, Ralf Bartenschlager, Giulio Superti-Furga

Virology. 2014 Aug; 462-463(100): 34–41. doi: 10.1016/j.virol.2014.05.016

PMCID:: PMC4139193

Abstract Article

Select item 336881717.

Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation

Glenn S. Van Aller, Nicolas Reynoird, Olena Barbash, Michael Huddleston, Shichong Liu, Anne-Flore Zmoos, Patrick McDevitt, Robert Sinnamon, BaoChau Le, Gloria Mas, Roland Annan, Julien Sage, Benjamin A. Garcia, Peter J. Tummino, Or Gozani, Ryan G. Kruger

Epigenetics. 2012 Apr 1; 7(4): 340–343. doi: 10.4161/epi.19506

PMCID:: PMC3368817

Abstract Article PDF–960K

Select item 313652118.

Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3

Kenneth W. Foreman, Mark Brown, Frances Park, Spencer Emtage, June Harriss, Chhaya Das, Li Zhu, Andy Crew, Lee Arnold, Salam Shaaban, Philip Tucker

PLoS One. 2011; 6(7): e22290. Published online 2011 Jul 14. doi: 10.1371/journal.pone.0022290

PMCID:: PMC3136521

Abstract Article PDF–807K

Select item 310540419.

Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding

Shutong Xu, Jian Wu, Bingfa Sun, Chen Zhong, Jianping Ding

Nucleic Acids Res. 2011 May; 39(10): 4438–4449. Published online 2011 Jan 25. doi: 10.1093/nar/gkr019

PMCID:: PMC3105404

Abstract Article PDF–9.8M

Select item 1097849220.

SMYD3: a new regulator of adipocyte precursor proliferation at the early steps of differentiation

Tatjana Sajic, Chayenne Karine Ferreira Gomes, Marie Gasser, Tiziana Caputo, Nasim Bararpour, Esther Landaluce-Iturriria, Marc Augsburger, Nadia Walter, Alexandre Hainard, Isabel C. Lopez-Mejia, Tony Fracasso, Aurélien Thomas, Federica Gilardi

Int J Obes (Lond) 2024; 48(4): 557–566. Published online 2023 Dec 26. doi: 10.1038/s41366-023-01450-x

PMCID:: PMC10978492

Abstract Article PDF–2.7M

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