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Items: 1 to 20 of 131

1.
Tumor-suppressive role of Smad ubiquitination regulatory factor 2 in patients with colorectal cancer
Nami Sato, Nozomu Sakai, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Gaku Ohira, Hideaki Miyauchi, Hisahiro Matsubara, Masayuki Ohtsuka
Sci Rep. 2022; 12: 5495. Published online 2022 Mar 31. doi: 10.1038/s41598-022-09390-8
PMCID:
PMC8971512
AbstractArticlePDF–3.6M
2.
Enriching the Arsenal of Pharmacological Tools against MICAL2
Ivana Barravecchia, Elisabetta Barresi, Camilla Russo, Francesca Scebba, Chiara De Cesari, Valerio Mignucci, Davide De Luca, Silvia Salerno, Valeria La Pietra, Mariateresa Giustiniano, Sveva Pelliccia, Diego Brancaccio, Greta Donati, Federico Da Settimo, Sabrina Taliani, Debora Angeloni, Luciana Marinelli
Molecules. 2021 Dec; 26(24): 7519. Published online 2021 Dec 11. doi: 10.3390/molecules26247519
PMCID:
PMC8709466
AbstractArticlePDF–3.2M
3.
Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled
Ondrej Bernatik, Petra Paclikova, Ranjani Sri Ganji, Vitezslav Bryja
Cells. 2020 May; 9(5): 1147. Published online 2020 May 7. doi: 10.3390/cells9051147
PMCID:
PMC7290506
AbstractArticlePDF–2.2M
4.
Effect of SMURF2 Targeting on Susceptibility to MEK Inhibitors in Melanoma
Michael P. Smith, Jennifer Ferguson, Imanol Arozarena, Robert Hayward, Richard Marais, Anna Chapman, Adam Hurlstone, Claudia Wellbrock
J Natl Cancer Inst. 2013 Jan 2; 105(1): 33–46. Published online 2012 Dec 29. doi: 10.1093/jnci/djs471
PMCID:
PMC3536641
AbstractArticlePDF–833K
5.
Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity and functional implication
Ruoyun Tan, Weichun He, Xia Lin, Lawrence P. Kiss, Youhua Liu
Am J Physiol Renal Physiol. Author manuscript; available in PMC 2009 Jun 29.
Published in final edited form as: Am J Physiol Renal Physiol. 2008 May; 294(5): F1076–F1083. Published online 2008 Mar 19. doi: 10.1152/ajprenal.00323.2007
PMCID:
PMC2703490
AbstractArticlePDF–1.9M
6.
Smad Ubiquitination Regulatory Factor 2 Promotes Metastasis of Breast Cancer Cells by Enhancing Migration and Invasiveness
Chaoyang Jin, Yu-an Yang, Miriam R. Anver, Nicole Morris, Xiangchun Wang, Ying E. Zhang
Cancer Res. Author manuscript; available in PMC 2010 Feb 1.
Published in final edited form as: Cancer Res. 2009 Feb 1; 69(3): 735–740. Published online 2009 Jan 20. doi: 10.1158/0008-5472.CAN-08-1463
PMCID:
PMC2639752
AbstractArticlePDF–908K
7.
Smurf2 up-regulation activates telomere-dependent senescence
Hong Zhang, Stanley N. Cohen
Genes Dev. 2004 Dec 15; 18(24): 3028–3040. doi: 10.1101/gad.1253004
PMCID:
PMC535914
AbstractArticlePDF–551K
8.
Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression
Yanan Pi, Qiushi Feng, Fusheng Sun, Zhiqiang Wang, Yue Zhao, Dejia Chen, Yiming Liu, Ge Lou
Cell Death Differ. 2023 Nov; 30(11): 2382–2392. Published online 2023 Oct 12. doi: 10.1038/s41418-023-01226-w
PMCID:
PMC10657365
AbstractArticlePDF–4.0M
9.
SMURF2 facilitates ubiquitin-mediated degradation of ID2 to attenuate lung cancer cell proliferation
Mingwei Han, Yixiao Guo, Yiming Li, Qingmei Zeng, Wanwan Zhu, Jianli Jiang
Int J Biol Sci. 2023; 19(11): 3324–3340. Published online 2023 Jun 26. doi: 10.7150/ijbs.80979
PMCID:
PMC10367561
AbstractArticlePDF–8.8M
10.
Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation
Bojie Lin, Dan Huang, Guanyu Lin, Yong Miao, Jin Wang, Zhexiang Fan, Zhiqi Hu
Cell Death Discov. 2022; 8: 160. Published online 2022 Apr 4. doi: 10.1038/s41420-022-00920-x
PMCID:
PMC8980066
AbstractArticlePDF–3.1M
11.
Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2
Dongqiang Song, Shuyu Li, Liuxin Ning, Shuncai Zhang, Yu Cai
Open Med (Wars) 2022; 17(1): 384–396. Published online 2022 Feb 24. doi: 10.1515/med-2022-0437
PMCID:
PMC8874264
AbstractArticlePDF–3.1M
12.
SMURF1 and SMURF2 in Progenitor Cells from Articular Cartilage and Meniscus during Late-Stage Osteoarthritis
Boris Schminke, Philipp Kauffmann, Andrea Schubert, Manuel Altherr, Thomas Gelis, Nicolai Miosge
Cartilage. 2021 Dec; 13(2 Suppl): 117S–128S. Published online 2020 Oct 22. doi: 10.1177/1947603520967069
PMCID:
PMC8721605
AbstractArticlePDF–3.6M
13.
SMAD‐specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis
Mengjun Ma, Wen Yang, Zhaopeng Cai, Peng Wang, Hongyu Li, Rujia Mi, Yuhang Jiang, Zhongyu Xie, Pengfei Sui, Yanfeng Wu, Huiyong Shen
Stem Cells. 2021 May; 39(5): 581–599. Published online 2021 Feb 6. doi: 10.1002/stem.3332
PMCID:
PMC8248389
AbstractArticlePDF–22M
14.
Circ_0116061 regulated the proliferation, apoptosis, and inflammation of osteoarthritis chondrocytes through regulating the miR-200b-3p/SMURF2 axis
Wei Zheng, Guanhua Hou, Yong Li
J Orthop Surg Res. 2021; 16: 253. Published online 2021 Apr 13. doi: 10.1186/s13018-021-02391-9
PMCID:
PMC8045261
AbstractArticlePDF–2.2M
15.
Development and characterisation of SMURF2-targeting modifiers
Dhanoop Manikoth Ayyathan, Gal Levy-Cohen, Moran Shubely, Sandy Boutros-Suleiman, Veronica Lepechkin-Zilbermintz, Michael Shokhen, Amnon Albeck, Arie Gruzman, Michael Blank
J Enzyme Inhib Med Chem. 2021; 36(1): 401–409. Published online 2021 Jan 12. doi: 10.1080/14756366.2020.1871337
PMCID:
PMC7808752
AbstractArticlePDF–3.0M
16.
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer
Yue Cui, Yang Song, Shi Yan, Mengru Cao, Jian Huang, Dexin Jia, Yuechao Liu, Shuai Zhang, Weina Fan, Li Cai, Chunhong Li, Ying Xing
Aging (Albany NY) 2020 Oct 31; 12(20): 20047–20068. Published online 2020 Oct 25. doi: 10.18632/aging.103329
PMCID:
PMC7655170
AbstractArticlePDF–3.6M
17.
TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2
Jinteng Li, Peng Wang, Zhongyu Xie, Shan Wang, Shuizhong Cen, Ming Li, Wenjie Liu, Su’an Tang, Guiwen Ye, Guan Zheng, Hongjun Su, Mengjun Ma, Xiaohua Wu, Yanfeng Wu, Huiyong Shen
Cell Death Differ. 2019 Dec; 26(12): 2652–2666. Published online 2019 May 10. doi: 10.1038/s41418-019-0328-3
PMCID:
PMC7224386
AbstractArticlePDF–4.1M
18.
The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress‐induced injury in human umbilical vein endothelial cells
Hao Qian, Naijin Zhang, Boquan Wu, Shaojun Wu, Shilong You, Ying Zhang, Yingxian Sun
J Cell Mol Med. 2020 Apr; 24(8): 4600–4611. Published online 2020 Mar 13. doi: 10.1111/jcmm.15121
PMCID:
PMC7176845
AbstractArticlePDF–1.5M
19.
The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation
Yakui Li, Dianqiang Yang, Na Tian, Ping Zhang, Yemin Zhu, Jian Meng, Ming Feng, Ying Lu, Qi Liu, Lingfeng Tong, Lei Hu, Lukuan Zhang, James Y. Yang, Lifang Wu, Xuemei Tong
J Biol Chem. 2019 Oct 4; 294(40): 14745–14756. Published online 2019 Aug 13. doi: 10.1074/jbc.RA119.007508
PMCID:
PMC6779433
AbstractArticlePDF–2.4M
20.
Substrate clustering potently regulates the activity of WW-HECT domain–containing ubiquitin ligases
Thomas Mund, Hugh R. Pelham
J Biol Chem. 2018 Apr 6; 293(14): 5200–5209. Published online 2018 Feb 20. doi: 10.1074/jbc.RA117.000934
PMCID:
PMC5892558
AbstractArticlePDF–2.7M

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