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Select item 77048631.

Signalosome-Regulated SRF Phosphorylation Determining Myocyte Growth in Width versus Length As a Therapeutic Target for Heart Failure

Jinliang Li, Yuliang Tan, Catherine L. Passariello, Eliana C. Martinez, Michael D. Kritzer, Xueyi Li, Xiaofeng Li, Yang Li, Qian Yu, Kenneth Ohgi, Hrishikesh Thakur, John W. MacArthur, Jr., Jan R. Ivey, Y. Joseph Woo, Craig A. Emter, Kimberly Dodge-Kafka, Michael G. Rosenfeld, Michael S. Kapiloff

Circulation. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Circulation. 2020 Dec; 142(22): 2138–2154. Published online 2020 Sep 16. doi: 10.1161/CIRCULATIONAHA.119.044805

PMCID:: PMC7704863

Abstract Article PDF–2.0M

Select item 63789682.

Muscle A-kinase–anchoring protein-β–bound calcineurin toggles active and repressive transcriptional complexes of myocyte enhancer factor 2D

Jinliang Li, Shania Aponte Paris, Hrishikesh Thakur, Michael S. Kapiloff, Kimberly L. Dodge-Kafka

J Biol Chem. 2019 Feb 15; 294(7): 2543–2554. Published online 2018 Dec 6. doi: 10.1074/jbc.RA118.005465

PMCID:: PMC6378968

Abstract Article PDF–2.8M

Select item 61061063.

PDE4 and mAKAPβ are nodal organizers of β₂-ARs nuclear PKA signalling in cardiac myocytes

Ibrahim Bedioune, Florence Lefebvre, Patrick Lechêne, Audrey Varin, Valérie Domergue, Michael S Kapiloff, Rodolphe Fischmeister, Grégoire Vandecasteele

Cardiovasc Res. 2018 Sep 1; 114(11): 1499–1511. Published online 2018 May 3. doi: 10.1093/cvr/cvy110

PMCID:: PMC6106106

Abstract Article PDF–1.2M

Select item 59405334.

Bidirectional regulation of HDAC5 by mAKAPβ signalosomes in cardiac myocytes

Kimberly L. Dodge-Kafka, Moriah Gildart, Jinliang Li, Hrishikesh Thakur, Michael S. Kapiloff

J Mol Cell Cardiol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: J Mol Cell Cardiol. 2018 May; 118: 13–25. Published online 2018 Mar 6. doi: 10.1016/j.yjmcc.2018.03.001

PMCID:: PMC5940533

Abstract Article PDF–1.6M

Select item 47037065.

Muscle A-Kinase Anchoring Protein-α is an Injury-Specific Signaling Scaffold Required for Neurotrophic- and Cyclic Adenosine Monophosphate-Mediated Survival

Yan Wang, Evan G. Cameron, Jinliang Li, Travis L. Stiles, Michael D. Kritzer, Rahul Lodhavia, Jonathan Hertz, Tu Nguyen, Michael S. Kapiloff, Jeffrey L. Goldberg

EBioMedicine. 2015 Dec; 2(12): 1880–1887. Published online 2015 Oct 28. doi: 10.1016/j.ebiom.2015.10.025

PMCID:: PMC4703706

Abstract Article PDF–1.3M

Select item 31230696.

Phospholipase Cϵ Scaffolds to Muscle-specific A Kinase Anchoring Protein (mAKAPβ) and Integrates Multiple Hypertrophic Stimuli in Cardiac Myocytes

Lianghui Zhang, Sundeep Malik, Grant G. Kelley, Michael S. Kapiloff, Alan V. Smrcka

J Biol Chem. 2011 Jul 1; 286(26): 23012–23021. Published online 2011 May 5. doi: 10.1074/jbc.M111.231993

PMCID:: PMC3123069

Abstract Article PDF–2.4M

Select item 21330497.

A-kinase Anchoring Protein 100 (AKAP100) is Localized in Multiple Subcellular Compartments in the Adult Rat Heart

Jiacheng Yang, Judith A. Drazba, Donald G. Ferguson, Meredith Bond

J Cell Biol. 1998 Jul 27; 142(2): 511–522. doi: 10.1083/jcb.142.2.511

PMCID:: PMC2133049

Abstract Article PDF–1.1M

Select item 48460968.

Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia

Thomas Wilhelm, Daniel B. Lipka, Tania Witte, Justyna A. Wierzbinska, Silvia Fluhr, Monika Helf, Oliver Mücke, Rainer Claus, Carolin Konermann, Peter Nöllke, Charlotte M. Niemeyer, Christian Flotho, Christoph Plass

Epigenetics. 2016 Feb; 11(2): 110–119. Published online 2016 Feb 18. doi: 10.1080/15592294.2016.1145327

PMCID:: PMC4846096

Abstract Article PDF–816K

Select item 43567469.

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

G Davies, N Armstrong, J C Bis, J Bressler, V Chouraki, S Giddaluru, E Hofer, C A Ibrahim-Verbaas, M Kirin, J Lahti, S J van der Lee, S Le Hellard, T Liu, R E Marioni, C Oldmeadow, I Postmus, A V Smith, J A Smith, A Thalamuthu, R Thomson, V Vitart, J Wang, L Yu, L Zgaga, W Zhao, R Boxall, S E Harris, W D Hill, D C Liewald, M Luciano, H Adams, D Ames, N Amin, P Amouyel, A A Assareh, R Au, J T Becker, A Beiser, C Berr, L Bertram, E Boerwinkle, B M Buckley, H Campbell, J Corley, P L De Jager, C Dufouil, J G Eriksson, T Espeseth, J D Faul, I Ford, Generation Scotland, R F Gottesman, M E Griswold, V Gudnason, T B Harris, G Heiss, A Hofman, E G Holliday, J Huffman, S L R Kardia, N Kochan, D S Knopman, J B Kwok, J-C Lambert, T Lee, G Li, S-C Li, M Loitfelder, O L Lopez, A J Lundervold, A Lundqvist, K A Mather, S S Mirza, L Nyberg, B A Oostra, A Palotie, G Papenberg, A Pattie, K Petrovic, O Polasek, B M Psaty, P Redmond, S Reppermund, J I Rotter, H Schmidt, M Schuur, P W Schofield, R J Scott, V M Steen, D J Stott, J C van Swieten, K D Taylor, J Trollor, S Trompet, A G Uitterlinden, G Weinstein, E Widen, B G Windham, J W Jukema, A F Wright, M J Wright, Q Yang, H Amieva, J R Attia, D A Bennett, H Brodaty, A J M de Craen, C Hayward, M A Ikram, U Lindenberger, L-G Nilsson, D J Porteous, K Räikkönen, I Reinvang, I Rudan, P S Sachdev, R Schmidt, P R Schofield, V Srikanth, J M Starr, S T Turner, D R Weir, J F Wilson, C van Duijn, L Launer, A L Fitzpatrick, S Seshadri, T H Mosley, Jr, I J Deary

Mol Psychiatry. 2015 Feb; 20(2): 183–192. Published online 2015 Feb 3. doi: 10.1038/mp.2014.188

PMCID:: PMC4356746

Abstract Article PDF–610K

Select item 310042710.

Temporal profile of Src, SSeCKS, and angiogenic factors after focal cerebral ischemia: correlations with angiogenesis and cerebral edema

Likun Zan, He Wu, Jie Jiang, Shiguang Zhao, Yuejia Song, Guoxin Teng, Heng Li, Ying Jia, Min Zhou, Xin Zhang, Jiping Qi, Jian Wang

Neurochem Int. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Neurochem Int. 2011 Jul; 58(8): 872–879. Published online 2011 Feb 18. doi: 10.1016/j.neuint.2011.02.014

PMCID:: PMC3100427

Abstract Article PDF–1.2M

Select item 113386611.

PKA-phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex

Jennifer J. Carlisle Michel, Kimberly L. Dodge, Wei Wong, Nicole C. Mayer, Lorene K. Langeberg, John D. Scott

Biochem J. 2004 Aug 1; 381(Pt 3): 587–592. Prepublished online 2004 Jun 8. Published online 2004 Jul 27. doi: 10.1042/BJ20040846

PMCID:: PMC1133866

Abstract Article PDF–468K

Select item 603479012.

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

Madalene Earp, Jonathan P. Tyrer, Stacey J. Winham, Hui-Yi Lin, Ganna Chornokur, Joe Dennis, Katja K. H. Aben, Hoda Anton‐Culver, Natalia Antonenkova, Elisa V. Bandera, Yukie T. Bean, Matthias W. Beckmann, Line Bjorge, Natalia Bogdanova, Louise A. Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Clareann H. Bunker, Ralf Butzow, Ian G. Campbell, Karen Carty, Jenny Chang-Claude, Linda S. Cook, Daniel W Cramer, Julie M. Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Evelyn Despierre, Jennifer A. Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Douglas F. Easton, Diana M. Eccles, Robert P. Edwards, Arif B. Ekici, Peter A. Fasching, Brooke L. Fridley, Aleksandra Gentry-Maharaj, Graham G. Giles, Rosalind Glasspool, Marc T. Goodman, Jacek Gronwald, Philipp Harter, Alexander Hein, Florian Heitz, Michelle A. T. Hildebrandt, Peter Hillemanns, Claus K. Hogdall, Estrid Høgdall, Satoyo Hosono, Edwin S. Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Audrey Y. Jung, Beth Y. Karlan, Melissa Kellar, Lambertus A. Kiemeney, Boon Kiong Lim, Susanne K. Kjaer, Camilla Krakstad, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Shashi Lele, Jenny Lester, Douglas A. Levine, Zheng Li, Dong Liang, Jolanta Lissowska, Karen Lu, Jan Lubinski, Lene Lundvall, Leon F. A. G. Massuger, Keitaro Matsuo, Valerie McGuire, John R. McLaughlin, Iain McNeish, Usha Menon, Roger L. Milne, Francesmary Modugno, Kirsten B. Moysich, Roberta B. Ness, Heli Nevanlinna, Kunle Odunsi, Sara H. Olson, Irene Orlow, Sandra Orsulic, James Paul, Tanja Pejovic, Liisa M. Pelttari, Jenny B. Permuth, Malcolm C. Pike, Elizabeth M. Poole, Barry Rosen, Mary Anne Rossing, Joseph H. Rothstein, Ingo B. Runnebaum, Iwona K. Rzepecka, Eva Schernhammer, Ira Schwaab, Xiao-Ou Shu, Yurii B. Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C. Southey, Beata Spiewankiewicz, Lara Sucheston-Campbell, Ingvild L. Tangen, Soo-Hwang Teo, Kathryn L. Terry, Pamela J. Thompson, Lotte Thomsen, Shelley S. Tworoger, Anne M. van Altena, Ignace Vergote, Liv Cecilie Vestrheim Thomsen, Robert A. Vierkant, Christine S. Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S. Whittemore, Kristine G. Wicklund, Lynne R. Wilkens, Yin-Ling Woo, Anna H. Wu, Xifeng Wu, Yong-Bing Xiang, Hannah Yang, Wei Zheng, Argyrios Ziogas, Alice W Lee, Celeste L. Pearce, Andrew Berchuck, Joellen M. Schildkraut, Susan J. Ramus, Alvaro N. A. Monteiro, Steven A. Narod, Thomas A. Sellers, Simon A. Gayther, Linda E. Kelemen, Georgia Chenevix-Trench, Harvey A. Risch, Paul D. P. Pharoah, Ellen L. Goode, Catherine M. Phelan

PLoS One. 2018; 13(7): e0197561. Published online 2018 Jul 6. doi: 10.1371/journal.pone.0197561

PMCID:: PMC6034790

Abstract Article PDF–2.4M

Select item 281337613.

The mAKAPβ Scaffold Regulates Cardiac Myocyte Hypertrophy via Recruitment of Activated Calcineurin

Jinliang Li, Alejandra Negro, Johanna Lopez, Andrea L. Bauman, Edward Henson, Kimberly Dodge-Kafka, Michael S. Kapiloff

J Mol Cell Cardiol. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: J Mol Cell Cardiol. 2010 Feb; 48(2): 387. Published online 2009 Oct 31. doi: 10.1016/j.yjmcc.2009.10.023

PMCID:: PMC2813376

Abstract Article PDF–1.4M

Select item 274912814.

An Adenylyl Cyclase-mAKAPβ Signaling Complex Regulates cAMP Levels in Cardiac Myocytes

Michael S. Kapiloff, Leslie A. Piggott, Rachna Sadana, Jinliang Li, Lorena A. Heredia, Edward Henson, Riad Efendiev, Carmen W. Dessauer

J Biol Chem. 2009 Aug 28; 284(35): 23540–23546. Published online 2009 Jul 1. doi: 10.1074/jbc.M109.030072

PMCID:: PMC2749128

Abstract Article PDF–2.8M

Select item 427786715.

The Scaffold Protein Muscle A-Kinase Anchoring Protein β Orchestrates Cardiac Myocyte Hypertrophic Signaling Required for the Development of Heart Failure

Michael D. Kritzer, Jinliang Li, Catherine L. Passariello, Marjorie Gayanilo, Hrishikesh Thakur, Joseph Dayan, Kimberly Dodge-Kafka, Michael S. Kapiloff

Circ Heart Fail. Author manuscript; available in PMC 2014 Dec 28.

Published in final edited form as: Circ Heart Fail. 2014 Jul; 7(4): 663–672. Published online 2014 May 8. doi: 10.1161/CIRCHEARTFAILURE.114.001266

PMCID:: PMC4277867

Abstract Article PDF–1.6M

Select item 356384716.

Regulation of MEF2 Transcriptional Activity by Calcineurin/mAKAP Complexes

Jinliang Li, Maximilian A.X. Vargas, Michael S. Kapiloff, Kimberly L. Dodge-Kafka

Exp Cell Res. Author manuscript; available in PMC 2014 Feb 15.

Published in final edited form as: Exp Cell Res. 2013 Feb 15; 319(4): 447–454. Published online 2012 Dec 21. doi: 10.1016/j.yexcr.2012.12.016

PMCID:: PMC3563847

Abstract Article PDF–2.5M

Select item 163658417.

The protein kinase A anchoring protein mAKAP co-ordinates two integrated cAMP effector pathways

Kimberly L. Dodge-Kafka, Joseph Soughayer, Genevieve C. Pare, Jennifer J. Carlisle Michel, Lorene K. Langeberg, Michael S. Kapiloff, John D. Scott

Nature. Author manuscript; available in PMC 2006 Nov 15.

Published in final edited form as: Nature. 2005 Sep 22; 437(7058): 574–578. doi: 10.1038/nature03966

PMCID:: PMC1636584

Abstract Article PDF–800K

Select item 285698318.

cAMP-stimulated Protein Phosphatase 2A Activity Associated with Muscle A Kinase-anchoring Protein (mAKAP) Signaling Complexes Inhibits the Phosphorylation and Activity of the cAMP-specific Phosphodiesterase PDE4D3

Kimberly L. Dodge-Kafka, Andrea Bauman, Nicole Mayer, Edward Henson, Lorena Heredia, Jung Ahn, Thomas McAvoy, Angus C. Nairn, Michael S. Kapiloff

J Biol Chem. 2010 Apr 9; 285(15): 11078–11086. Published online 2010 Jan 27. doi: 10.1074/jbc.M109.034868

PMCID:: PMC2856983

Abstract Article PDF–1.3M

Select item 12542919.

mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module

Kimberly L. Dodge, Samone Khouangsathiene, Michael S. Kapiloff, Robert Mouton, Elaine V. Hill, Miles D. Houslay, Lorene K. Langeberg, John D. Scott

EMBO J. 2001 Apr 17; 20(8): 1921–1930. doi: 10.1093/emboj/20.8.1921

PMCID:: PMC125429

Abstract Article PDF–358K

Select item 286737820.

The contribution of AKAP5 in amylase secretion from mouse parotid acini

Ching-Yi Wu, Dennis H. DiJulio, Kerry L. Jacobson, G. Stanley McKnight, Eileen L. Watson

Am J Physiol Cell Physiol. 2010 May; 298(5): C1151–C1158. Published online 2010 Feb 17. doi: 10.1152/ajpcell.00382.2009

PMCID:: PMC2867378

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