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Select item 82786281.

Heme degradation enzyme biliverdin IXβ reductase is required for stem cell glutamine metabolism

Zongdong Li, Natasha M. Nesbitt, Lisa E. Malone, Dimitri V. Gnatenko, Song Wu, Daifeng Wang, Wei Zhu, Geoffrey D. Girnun, Wadie F. Bahou

Biochem J. Author manuscript; available in PMC 2021 Jul 14.

Published in final edited form as: Biochem J. 2018 Mar 29; 475(6): 1211–1223. Published online 2018 Mar 29. doi: 10.1042/BCJ20180016

PMCID:: PMC8278628

Abstract Article PDF–1.7M

Select item 59007822.

In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency

Natasha M. Nesbitt, Xiliang Zheng, Zongdong Li, José A. Manso, Wan-Yi Yen, Lisa E. Malone, Jorge Ripoll-Rozada, Pedro José Barbosa Pereira, Timothy J. Mantle, Jin Wang, Wadie F. Bahou

J Biol Chem. 2018 Apr 13; 293(15): 5431–5446. Published online 2018 Feb 27. doi: 10.1074/jbc.RA118.001803

PMCID:: PMC5900782

Abstract Article PDF–3.3M

Select item 49742013.

BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans

Song Wu, Zongdong Li, Dmitri V. Gnatenko, Beibei Zhang, Lu Zhao, Lisa E. Malone, Nedialka Markova, Timothy J. Mantle, Natasha M. Nesbitt, Wadie F. Bahou

Blood. 2016 Aug 4; 128(5): 699–709. Prepublished online 2016 May 16. doi: 10.1182/blood-2016-02-696997

PMCID:: PMC4974201

Abstract Article

Select item 12173614.

Evidence that biliverdin-IX beta reductase and flavin reductase are identical.

F Shalloe, G Elliott, O Ennis, T J Mantle

Biochem J. 1996 Jun 1; 316(Pt 2): 385–387. doi: 10.1042/bj3160385

PMCID:: PMC1217361

Summary PDF–308K

Select item 102963905.

Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis

Melody Chemaly, David Marlevi, Maria-Jesus Iglesias, Mariette Lengquist, Malin Kronqvist, Daniel Bos, Dianne H. K. van Dam-Nolen, Anja van der Kolk, Jeroen Hendrikse, Mohamed Kassem, Ljubica Matic, Jacob Odeberg, Margreet R. de Vries, M. Eline Kooi, Ulf Hedin

Biomolecules. 2023 Jun; 13(6): 882. Published online 2023 May 24. doi: 10.3390/biom13060882

PMCID:: PMC10296390

Abstract Article PDF–3.1M

Select item 48142446.

MicroRNA‐127‐5p targets the biliverdin reductase B/nuclear factor‐κB pathway to suppress cell growth in hepatocellular carcinoma cells

Lin Huan, Chunyang Bao, Di Chen, Yan Li, Junwei Lian, Jie Ding, Shenglin Huang, Linhui Liang, Xianghuo He

Cancer Sci. 2016 Mar; 107(3): 258–266. Published online 2016 Feb 9. doi: 10.1111/cas.12869

PMCID:: PMC4814244

Abstract Article PDF–1.9M

Select item 43805277.

Biliverdin Reductase Isozymes in Metabolism

Luke O'Brien, Peter A. Hosick, Kezia John, David E. Stec, Terry D. Hinds, Jr.

Trends Endocrinol Metab. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Trends Endocrinol Metab. 2015 Apr; 26(4): 212–220. Published online 2015 Feb 25. doi: 10.1016/j.tem.2015.02.001

PMCID:: PMC4380527

Abstract Article PDF–1006K

Select item 52863808.

The pseudophosphatase STYX targets the F‐box of FBXW7 and inhibits SCF^FBXW7 function

Veronika Reiterer, Cristina Figueras‐Puig, Francois Le Guerroue, Stefano Confalonieri, Manuela Vecchi, Dasaradha Jalapothu, Sandip M Kanse, Raymond J Deshaies, Pier Paolo Di Fiore, Christian Behrends, Hesso Farhan

EMBO J. 2017 Feb 1; 36(3): 260–273. Published online 2016 Dec 22. doi: 10.15252/embj.201694795

Correction in:: EMBO J. 2018 Mar 15; 37(6): e99170.

PMCID:: PMC5286380

Abstract Article PDF–2.4M

Select item 92265109.

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia

Linjiang Lao, Isabelle Bourdeau, Lucia Gagliardi, Xiao He, Wei Shi, Bingbing Hao, Minjia Tan, Yan Hu, Junzheng Peng, Benoit Coulombe, David J Torpy, Hamish S Scott, Andre Lacroix, Hongyu Luo, Jiangping Wu

Nucleic Acids Res. 2022 Jun 24; 50(11): 6343–6367. Published online 2022 Jun 10. doi: 10.1093/nar/gkac483

PMCID:: PMC9226510

Abstract Article PDF–3.7M

Select item 596587210.

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrP^C) in Alzheimer’s disease

Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt

PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659

PMCID:: PMC5965872

Abstract Article PDF–2.4M

Select item 764586311.

N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

Tomas Koudelka, Juliane Boger, Alessandra Henkel, Robert Schönherr, Stefanie Krantz, Sabine Fuchs, Estefanía Rodríguez, Lars Redecke, Andreas Tholey

Proteomics. 2021 Jan; 21(2): 2000246. Published online 2020 Nov 17. doi: 10.1002/pmic.202000246

PMCID:: PMC7645863

Abstract Article PDF–497K

Select item 856647312.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 1007290613.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 629516514.

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel

Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118

PMCID:: PMC6295165

Abstract Article PDF–3.5M

Select item 739233415.

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull

PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606

PMCID:: PMC7392334

Abstract Article PDF–2.7M

Select item 977255816.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 674682217.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

Select item 732206718.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 698120619.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 263705020.

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper

J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406

PMCID:: PMC2637050

Abstract Article

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