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Select item 110121191.

Gene Expression Profiling Reveals Fundamental Sex-Specific Differences in SIRT3-Mediated Redox and Metabolic Signaling in Mouse Embryonic Fibroblasts

Robert Belužić, Ena Šimunić, Iva I. Podgorski, Marija Pinterić, Marijana Popović Hadžija, Tihomir Balog, Sandra Sobočanec

Int J Mol Sci. 2024 Apr; 25(7): 3868. Published online 2024 Mar 30. doi: 10.3390/ijms25073868

PMCID:: PMC11012119

Abstract Article PDF–3.4M

Select item 107778842.

Sirtuin 3 is required for the dexmedetomidine‐mediated alleviation of inflammation and oxidative stress in nephritis

Kai Lu, Xinlong Li, Jie Wu

Immun Inflamm Dis. 2024 Jan; 12(1): e1135. Published online 2024 Jan 10. doi: 10.1002/iid3.1135

PMCID:: PMC10777884

Abstract Article PDF–3.0M

Select item 106636913.

Exogenous NADPH exerts a positive inotropic effect and enhances energy metabolism via SIRT3 in pathological cardiac hypertrophy and heart failure

Ke Qian, Jie Tang, Yue-Juan Ling, Ming Zhou, Xin-Xin Yan, Yu Xie, Lu-Jia Zhu, Koju Nirmala, Kang-Yun Sun, Zheng-Hong Qin, Rui Sheng

eBioMedicine. 2023 Dec; 98: 104863. Published online 2023 Nov 9. doi: 10.1016/j.ebiom.2023.104863

PMCID:: PMC10663691

Abstract Article PDF–4.9M

Select item 105641634.

Sirt3 deficiency promotes endothelial dysfunction and aggravates renal injury

Anna Pezzotta, Luca Perico, Daniela Corna, Marina Morigi, Giuseppe Remuzzi, Ariela Benigni, Barbara Imberti

PLoS One. 2023; 18(10): e0291909. Published online 2023 Oct 10. doi: 10.1371/journal.pone.0291909

PMCID:: PMC10564163

Abstract Article PDF–3.1M

Select item 104988725.

SIRT3 Regulates Clearance of Apoptotic Cardiomyocytes by Deacetylating Frataxin

Jing Gao, Chenglin Huang, Linghui Kong, Wugang Zhou, Mengwei Sun, Tong Wei, Weili Shen

Circ Res. 2023 Sep 15; 133(7): 631–647. Published online 2023 Aug 30. doi: 10.1161/CIRCRESAHA.123.323160

PMCID:: PMC10498872

Abstract Article PDF–14M

Select item 104965056.

Sirtuin-3 activates the mitochondrial unfolded protein response and reduces cerebral ischemia/reperfusion injury

Xie Xiaowei, Xu Qian, Zhou Dingzhou

Int J Biol Sci. 2023; 19(13): 4327–4339. Published online 2023 Aug 21. doi: 10.7150/ijbs.86614

PMCID:: PMC10496505

Abstract Article PDF–12M

Select item 102354697.

SIRT3 alleviates imiquimod-induced psoriatic dermatitis through deacetylation of XBP1s and modulation of TLR7/8 inducing IL-23 production in macrophages

Meiliang Guo, Haojun Zhuang, Yimin Su, Qinqin Meng, Wanwen Liu, Na Liu, Min Wei, Sheng-Ming Dai, Hui Deng

Front Immunol. 2023; 14: 1128543. Published online 2023 May 19. doi: 10.3389/fimmu.2023.1128543

PMCID:: PMC10235469

Abstract Article PDF–13M

Select item 101012988.

Effect of electroacupuncture treatment combined with rehabilitation care on serum sirt3 level and motor function in elderly patients with stroke hemiparesis

Ying Shen, Liping Hu, Jing Ge, Ling Li

Medicine (Baltimore) 2023 Apr 14; 102(15): e33403. Published online 2023 Apr 14. doi: 10.1097/MD.0000000000033403

PMCID:: PMC10101298

Abstract Article PDF–539K

Select item 100818089.

Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model

Antiño R. Allen, A’Vonte Jones, Francesca V. LoBianco, Kimberly J. Krager, Nukhet Aykin-Burns

Behav Brain Res. Author manuscript; available in PMC 2024 Apr 27.

Published in final edited form as: Behav Brain Res. 2023 Apr 27; 444: 114335. Published online 2023 Feb 15. doi: 10.1016/j.bbr.2023.114335

PMCID:: PMC10081808

Abstract Article PDF–1.3M

Select item 1001045310.

Neuronal SIRT3 Deletion Predisposes to Female-Specific Alterations in Cellular Metabolism, Memory, and Network Excitability

Jennifer N. Pearson-Smith, Ruth Fulton, Christopher Q. Huynh, Anna G. Figueroa, Gia B. Huynh, Li-Ping Liang, Lindsey B. Gano, Cole R. Michel, Nichole Reisdorph, Richard Reisdorph, Kristofer S. Fritz, Eric Verdin, Manisha Patel

J Neurosci. 2023 Mar 8; 43(10): 1845–1857. doi: 10.1523/JNEUROSCI.1259-22.2023

PMCID:: PMC10010453

Abstract Article PDF–2.6M

Select item 988673611.

The loss of cardiac SIRT3 decreases metabolic flexibility and proteostasis in an age-dependent manner

Ping Li, Maria F. Newhardt, Satoshi Matsuzaki, Craig Eyster, Atul Pranay, Frederick F. Peelor, 3rd, Albert Batushansky, Caroline Kinter, Kumar Subramani, Sandeep Subrahmanian, Jasimuddin Ahamed, Pengchun Yu, Michael Kinter, Benjamin F. Miller, Kenneth M. Humphries

GeroScience. 2023 Apr; 45(2): 983–999. Published online 2022 Dec 3. doi: 10.1007/s11357-022-00695-0

PMCID:: PMC9886736

Abstract Article PDF–6.7M

Select item 988326412.

Sirt3 mediates the benefits of exercise on bone in aged mice

Qiangqiang Li, Rongliang Wang, Zhe Zhang, Haixing Wang, Xiaomin Lu, Jiajun Zhang, Alice Pik-Shan Kong, Xiao Yu Tian, Hon-Fai Chan, Arthur Chi-Kong Chung, Jack Chun-Yiu Cheng, Qing Jiang, Wayne Yuk-Wai Lee

Cell Death Differ. 2023 Jan; 30(1): 152–167. Published online 2022 Sep 24. doi: 10.1038/s41418-022-01053-5

PMCID:: PMC9883264

Abstract Article PDF–6.9M

Select item 981047113.

Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerates Age-Related Aβ Pathology, and Renders Neurons Vulnerable to Aβ Toxicity

Isabella Perone, Nathaniel Ghena, Jing Wang, Chelsea Mackey, Ruiqian Wan, Sulochan Malla, Myriam Gorospe, Aiwu Cheng, Mark P. Mattson

Neuromolecular Med. Author manuscript; available in PMC 2023 Mar 23.

Published in final edited form as: Neuromolecular Med. 2023 Mar; 25(1): 27–39. Published online 2022 Jun 24. doi: 10.1007/s12017-022-08713-2

PMCID:: PMC9810471

Abstract Article PDF–1.9M

Select item 974151114.

SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction

Rashpal S. Dhillon, Yiming (Amy) Qin, Paul R. van Ginkel, Vivian X. Fu, James M. Vann, Alexis J. Lawton, Cara L. Green, Fúlvia B. Manchado‐Gobatto, Claudio A. Gobatto, Dudley W. Lamming, Tomas A. Prolla, John M. Denu

Aging Cell. 2022 Dec; 21(12): e13721. Published online 2022 Oct 5. doi: 10.1111/acel.13721

PMCID:: PMC9741511

Abstract Article PDF–5.1M

Select item 970865415.

Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation

Andrew R. Hall, Qutuba G. Karwi, Sanjeev Kumar, Rachel Dongworth, Dunja Aksentijević, Tariq R. Altamimi, Kevin Timothy Fridianto, Kroekkiat Chinda, Sauri Hernandez-Resendiz, Mohammad U. Mahmood, Evangelos Michelakis, Chrishan J. Ramachandra, Jianhong Ching, Jose M. Vicencio, Michael J. Shattock, Jean-Paul Kovalik, Derek M. Yellon, Gary Lopaschuk, Derek J. Hausenloy

Sci Rep. 2022; 12: 20551. Published online 2022 Nov 29. doi: 10.1038/s41598-022-23847-w

PMCID:: PMC9708654

Abstract Article PDF–3.3M

Select item 967209516.

Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer’s disease with metabolic syndrome

Alpna Tyagi, Musa Musa, Wladimir Labeikovsky, Subbiah Pugazhenthi

Sci Rep. 2022; 12: 19808. Published online 2022 Nov 17. doi: 10.1038/s41598-022-23652-5

PMCID:: PMC9672095

Abstract Article PDF–2.9M

Select item 960022817.

Low Nephron Number Induced by Maternal Protein Restriction Is Prevented by Nicotinamide Riboside Supplementation Depending on Sirtuin 3 Activation

Anna Pezzotta, Luca Perico, Marina Morigi, Daniela Corna, Monica Locatelli, Carlamaria Zoja, Ariela Benigni, Giuseppe Remuzzi, Barbara Imberti

Cells. 2022 Oct; 11(20): 3316. Published online 2022 Oct 21. doi: 10.3390/cells11203316

PMCID:: PMC9600228

Abstract Article PDF–3.3M

Select item 953500918.

Activating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome

Tianli Shen, Yunhua Wu, Xingjie Wang, Zijun Wang, Enmeng Li, Cancan Zhou, Chenyang Yue, Zhengdong Jiang, Guangbing Wei, Jie Lian, Qinhong Xu, Xuqi Li

Exp Mol Med. 2022 Sep; 54(9): 1486–1501. Published online 2022 Sep 13. doi: 10.1038/s12276-022-00848-3

PMCID:: PMC9535009

Abstract Article PDF–10M

Select item 952782219.

Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke

Rajkumar Verma, Rodney M. Ritzel, Joshua Crapser, Brett D. Friedler, Louise D. McCullough

Transl Stroke Res. Author manuscript; available in PMC 2022 Oct 3.

Published in final edited form as: Transl Stroke Res. 2019 Feb; 10(1): 57–66. Published online 2018 Jan 4. doi: 10.1007/s12975-017-0603-x

PMCID:: PMC9527822

Abstract Article PDF–2.3M

Select item 936863420.

Sirtuin 3 Deficiency Aggravates Kidney Disease in Response to High-Fat Diet through Lipotoxicity-Induced Mitochondrial Damage

Monica Locatelli, Daniela Macconi, Daniela Corna, Domenico Cerullo, Daniela Rottoli, Giuseppe Remuzzi, Ariela Benigni, Carlamaria Zoja

Int J Mol Sci. 2022 Aug; 23(15): 8345. Published online 2022 Jul 28. doi: 10.3390/ijms23158345

PMCID:: PMC9368634

Abstract Article PDF–7.9M

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