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Select item 111929441.

PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma

Sheng-Yan Huang, Sha Gong, Yin Zhao, Ming-Liang Ye, Jun-Yan Li, Qing-Mei He, Han Qiao, Xi-Rong Tan, Jing-Yun Wang, Ye-Lin Liang, Sai-Wei Huang, Shi-Wei He, Ying-Qin Li, Sha Xu, Ying-Qing Li, Na Liu

Nat Commun. 2024; 15: 5300. Published online 2024 Jun 21. doi: 10.1038/s41467-024-49675-2

PMCID:: PMC11192944

Abstract Article PDF–5.0M

Select item 73591102.

A recurrent PJA1 variant in trigonocephaly and neurodevelopmental disorders

Toshimitsu Suzuki, Toshifumi Suzuki, Matthieu Raveau, Noriko Miyake, Genki Sudo, Yoshinori Tsurusaki, Takaki Watanabe, Yuki Sugaya, Tetsuya Tatsukawa, Emi Mazaki, Atsushi Shimohata, Itaru Kushima, Branko Aleksic, Tomoko Shiino, Tomoko Toyota, Yoshimi Iwayama, Kentaro Nakaoka, Iori Ohmori, Aya Sasaki, Ken Watanabe, Shinichi Hirose, Sunao Kaneko, Yushi Inoue, Takeo Yoshikawa, Norio Ozaki, Masanobu Kano, Takeyoshi Shimoji, Naomichi Matsumoto, Kazuhiro Yamakawa

Ann Clin Transl Neurol. 2020 Jul; 7(7): 1117–1131. Published online 2020 Jun 12. doi: 10.1002/acn3.51093

PMCID:: PMC7359110

Abstract Article PDF–1.8M

Select item 91242783.

OTUB2 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells by PJA1 Deubiquitylation

Gang Hu, Jianwu Yang, Hongwen Zhang, Zhen Huang, Heming Yang

Cell Mol Bioeng. 2022 Jun; 15(3): 281–292. Published online 2022 Feb 1. doi: 10.1007/s12195-022-00720-4

PMCID:: PMC9124278

Abstract Article PDF–3.2M

Select item 83517494.

Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity

Baijayanti Ghosh, Susnata Karmakar, Mohit Prasad, Atin K. Mandal

Mol Biol Cell. 2021 Aug 15; 32(17): 1579–1593. doi: 10.1091/mbc.E20-11-0747

PMCID:: PMC8351749

Abstract Article PDF–5.2M

Select item 78182555.

Praja1 RING‐finger E3 ubiquitin ligase suppresses neuronal cytoplasmic TDP‐43 aggregate formation

Kazuhiko Watabe, Yoichiro Kato, Miho Sakuma, Makiko Murata, Motoko Niida‐Kawaguchi, Taro Takemura, Nobutaka Hanagata, Mari Tada, Akiyoshi Kakita, Noriyuki Shibata

Neuropathology. 2020 Dec; 40(6): 570–586. Published online 2020 Jul 19. doi: 10.1111/neup.12694

PMCID:: PMC7818255

Abstract Article PDF–13M

Select item 77041016.

Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGF-β Signaling

Jian Chen, Abhisek Mitra, Shulin Li, Shumei Song, Bao-Ngoc Nguyen, Jiun-Sheng Chen, Ji-hyun Shin, Nancy R. Gough, Paul Lin, Vincent Obias, Aiwu Ruth He, Zhixing Yao, Tathiane M Malta, Houtan Noushmehr, Patricia S. Latham, Xiaoping Su, Asif Rashid, Bibhuti Mishra, Ray-Chang Wu, Lopa Mishra

Cancer Res. Author manuscript; available in PMC 2020 Nov 30.

Published in final edited form as: Cancer Res. 2020 May 1; 80(9): 1819–1832. Published online 2020 Mar 3. doi: 10.1158/0008-5472.CAN-19-3116

PMCID:: PMC7704101

Abstract Article PDF–2.8M

Select item 54232707.

Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation

Silvia Consalvi, Arianna Brancaccio, Alessandra Dall'Agnese, Pier Lorenzo Puri, Daniela Palacios

Nat Commun. 2017; 8: 13956. Published online 2017 Jan 9. doi: 10.1038/ncomms13956

PMCID:: PMC5423270

Abstract Article PDF–2.4M

Select item 62064848.

PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner

Wei Xu, Chunqiang Ma, Qi Zhang, Rong Zhao, Dan Hu, Xuewu Zhang, Junbo Chen, Fang Liu, Kailang Wu, Yingle Liu, Jianguo Wu

J Virol. 2018 Nov 15; 92(22): e00825-18. Prepublished online 2018 Sep 5. Published online 2018 Oct 29. doi: 10.1128/JVI.00825-18

PMCID:: PMC6206484

Abstract Article PDF–5.1M

Select item 96349779.

A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase

Jingjing Ruan, Dongdong Liang, Wenjing Yan, Yongwang Zhong, Daniel C. Talley, Ganesha Rai, Dingyin Tao, Christopher A. LeClair, Anton Simeonov, Yinghua Zhang, Feihu Chen, Nancy L. Quinney, Susan E. Boyles, Deborah M. Cholon, Martina Gentzsch, Mark J. Henderson, Fengtian Xue, Shengyun Fang

Mol Biol Cell. 2022 Nov 1; 33(13): ar120. Published online 2022 Nov 1. doi: 10.1091/mbc.E22-06-0233

PMCID:: PMC9634977

Abstract Article PDF–5.8M

Select item 1008412410.

Praja1 RING‐finger E3 ubiquitin ligase is a common suppressor of neurodegenerative disease‐associated protein aggregation

Kazuhiko Watabe, Motoko Niida‐Kawaguchi, Mari Tada, Yoichiro Kato, Makiko Murata, Kunikazu Tanji, Koichi Wakabayashi, Mitsunori Yamada, Akiyoshi Kakita, Noriyuki Shibata

Neuropathology. 2022 Dec; 42(6): 488–504. Published online 2022 Jun 14. doi: 10.1111/neup.12840

PMCID:: PMC10084124

Abstract Article PDF–4.8M

Select item 749085211.

The E3 Ubiquitin Ligase SYVN1 Ubiquitinates Atlastins to Remodel the Endoplasmic Reticulum Network

Yupeng Zhao, Zhigang Feng, Yan Zou, Yanfen Liu

iScience. 2020 Sep 25; 23(9): 101494. Published online 2020 Aug 24. doi: 10.1016/j.isci.2020.101494

PMCID:: PMC7490852

Abstract Article PDF–42M

Select item 337553912.

Ubiquitin-specific Peptidase 9, X-linked (USP9X) Modulates Activity of Mammalian Target of Rapamycin (mTOR)

Pooja Agrawal, Yu-Ting Chen, Birgit Schilling, Bradford W. Gibson, Robert E. Hughes

J Biol Chem. 2012 Jun 15; 287(25): 21164–21175. Published online 2012 Apr 27. doi: 10.1074/jbc.M111.328021

Correction in:: J Biol Chem. 2014 May 23; 289(21): 14965.

PMCID:: PMC3375539

Abstract Article PDF–1.4M

Select item 711391313.

A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate

Christian M. Loch, James E. Strickler

Biochim Biophys Acta Mol Cell Res. 2012 Nov; 1823(11): 2069–2078. Published online 2012 May 21. doi: 10.1016/j.bbamcr.2012.05.006

PMCID:: PMC7113913

Abstract Article PDF–1.5M

Select item 450978814.

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

Jennifer M. Doyle, Jinlan Gao, Jiawei Wang, Maojun Yang, Patrick Ryan Potts

Mol Cell. Author manuscript; available in PMC 2015 Jul 21.

Published in final edited form as: Mol Cell. 2010 Sep 24; 39(6): 963–974. doi: 10.1016/j.molcel.2010.08.029

PMCID:: PMC4509788

Abstract Article PDF–1.3M

Select item 270004815.

Identification of Novel Smad2 and Smad3 Associated Proteins in Response to TGF-β1

Kimberly A. Brown, Amy-Joan L. Ham, Cara N. Clark, Nahum Meller, Brian K. Law, Anna Chytil, Nikki Cheng, Jennifer A. Pietenpol, Harold L. Moses

J Cell Biochem. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: J Cell Biochem. 2008 Oct 1; 105(2): 596–611. doi: 10.1002/jcb.21860

PMCID:: PMC2700048

Abstract Article PDF–1.1M

Select item 1002268616.

Myosin-X recruits lamellipodin to filopodia tips

Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L. B. Grönloh, Neil J. Ball, Benjamin T. Goult, Johanna Ivaska, Guillaume Jacquemet

J Cell Sci. 2023 Mar 1; 136(5): jcs260574. Published online 2023 Mar 2. doi: 10.1242/jcs.260574

PMCID:: PMC10022686

Abstract Article

Select item 400417617.

Proximity Interactions Among Centrosome Components Identify Regulators of Centriole Duplication

Elif Nur Firat-Karalar, Navin Rauniyar, John R. Yates, III, Tim Stearns

Curr Biol. Author manuscript; available in PMC 2015 Mar 17.

Published in final edited form as: Curr Biol. 2014 Mar 17; 24(6): 664–670. Published online 2014 Mar 6. doi: 10.1016/j.cub.2014.01.067

PMCID:: PMC4004176

Abstract Article PDF–1.4M

Select item 273665218.

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

Sjoerd J L van Wijk, Sjoerd J de Vries, Patrick Kemmeren, Anding Huang, Rolf Boelens, Alexandre M J J Bonvin, H Th Marc Timmers

Mol Syst Biol. 2009; 5: 295. Published online 2009 Aug 18. doi: 10.1038/msb.2009.55

Correction in:: Mol Syst Biol. 2009; 5: 317.

PMCID:: PMC2736652

Abstract Article PDF–5.6M

Select item 866666519.

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

Jean-Philippe Guégan, Justine Pollet, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Marcus E. Peter, Patrick Legembre

iScience. 2021 Dec 17; 24(12): 103538. Published online 2021 Dec 1. doi: 10.1016/j.isci.2021.103538

PMCID:: PMC8666665

Abstract Article PDF–3.2M

Select item 325365820.

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

Shitao Li, Lingyan Wang, Michael Berman, Young-Yun Kong, Martin E. Dorf

Immunity. Author manuscript; available in PMC 2012 Sep 23.

Published in final edited form as: Immunity. 2011 Sep 23; 35(3): 426–440. Published online 2011 Sep 8. doi: 10.1016/j.immuni.2011.06.014

Correction in:: volume 35 on page 647

PMCID:: PMC3253658

Abstract Article PDF–4.2M

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