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Select item 110716521.

FIGNL1 Promotes Hepatocellular Carcinoma Formation via Remodeling ECM-receptor Interaction Pathway Mediated by HMMR

Jiabei Wang, Linmao Sun, Yao Liu, Yunguang Zhang

Curr Gene Ther. 2024 Feb 7; 24(3): 249–263. Published online 2024 Feb 7. doi: 10.2174/0115665232274223231017052707

PMCID:: PMC11071652

Abstract Article PDF–5.6M

Select item 77210852.

FIGNL1 promotes non-small cell lung cancer cell proliferation

Miao Li, Yan Rui, Wenjia Peng, Junfeng Hu, Anbang Jiang, Zeyu Yang, Linian Huang

Int J Oncol. 2021 Jan; 58(1): 83–99. Published online 2020 Dec 1. doi: 10.3892/ijo.2020.5154

PMCID:: PMC7721085

Abstract Article PDF–4.3M

Select item 53673423.

FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide

Jian Ma, Jianlei Li, Xiaoling Yao, Shuangjun Lin, Ye Gu, Jianfang Xu, Zixin Deng, Wei Ma, Haiping Zhang

Oncol Rep. 2017 Apr; 37(4): 1935–1942. Published online 2017 Mar 1. doi: 10.3892/or.2017.5483

PMCID:: PMC5367342

Abstract Article PDF–653K

Select item 111627934.

Human AAA+ ATPase FIGNL1 suppresses RAD51-mediated ultra-fine bridge formation

Kenichiro Matsuzaki, Akira Shinohara, Miki Shinohara

Nucleic Acids Res. 2024 Jun 10; 52(10): 5774–5791. Published online 2024 Apr 10. doi: 10.1093/nar/gkae263

PMCID:: PMC11162793

Abstract Article PDF–1.7M

Select item 108251455.

FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote viability after replication stress

Jessica D. Tischler, Hiroshi Tsuchida, Rosevalentine Bosire, Tommy T. Oda, Ana Park, Richard O. Adeyemi

Nat Commun. 2024; 15: 866. Published online 2024 Jan 29. doi: 10.1038/s41467-024-45139-9

PMCID:: PMC10825145

Abstract Article PDF–3.0M

Select item 50046976.

Fidgetin-like 1 is a ciliogenesis-inhibitory centrosome protein

Xiaoyu Zhao, Miaomiao Jin, Mengzhu Wang, Lili Sun, Xuejiao Hong, Ying Cao, Chunguang Wang

Cell Cycle. 2016; 15(17): 2367–2375. Published online 2016 Jul 6. doi: 10.1080/15384101.2016.1204059

PMCID:: PMC5004697

Abstract Article PDF–991K

Select item 64409947.

Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase

Kenichiro Matsuzaki, Shizuka Kondo, Tatsuya Ishikawa, Akira Shinohara

Nat Commun. 2019; 10: 1407. Published online 2019 Mar 29. doi: 10.1038/s41467-019-09190-1

PMCID:: PMC6440994

Abstract Article PDF–2.5M

Select item 68211878.

The human Shu complex functions with PDS5B and SPIDR to promote homologous recombination

Julieta Martino, Gregory J Brunette, Jonathan Barroso-González, Tatiana N Moiseeva, Chelsea M Smith, Christopher J Bakkenist, Roderick J O’Sullivan, Kara A Bernstein

Nucleic Acids Res. 2019 Nov 4; 47(19): 10151–10165. Published online 2019 Sep 6. doi: 10.1093/nar/gkz738

PMCID:: PMC6821187

Abstract Article PDF–6.2M

Select item 67814359.

FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation

Melody Atkins, Laïla Gasmi, Valérie Bercier, Céline Revenu, Filippo Del Bene, Jamilé Hazan, Coralie Fassier

J Cell Biol. 2019 Oct 7; 218(10): 3290–3306. Published online 2019 Sep 19. doi: 10.1083/jcb.201805128

PMCID:: PMC6781435

Abstract Article PDF–3.5M

Select item 1061173310.

FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination

Masaru Ito, Asako Furukohri, Kenichiro Matsuzaki, Yurika Fujita, Atsushi Toyoda, Akira Shinohara

Nat Commun. 2023; 14: 6857. Published online 2023 Oct 27. doi: 10.1038/s41467-023-42576-w

PMCID:: PMC10611733

Abstract Article PDF–5.5M

Select item 589703311.

FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination

Joiselle Blanche Fernandes, Marine Duhamel, Mathilde Seguéla-Arnaud, Nicole Froger, Chloé Girard, Sandrine Choinard, Victor Solier, Nancy De Winne, Geert De Jaeger, Kris Gevaert, Philippe Andrey, Mathilde Grelon, Raphael Guerois, Rajeev Kumar, Raphaël Mercier

PLoS Genet. 2018 Apr; 14(4): e1007317. Published online 2018 Apr 2. doi: 10.1371/journal.pgen.1007317

PMCID:: PMC5897033

Abstract Article PDF–26M

Select item 369676912.

Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair

Li Wan, Jinhua Han, Ting Liu, Shunli Dong, Feng Xie, Hongxia Chen, Jun Huang

Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10646–10651. Published online 2013 Mar 18. doi: 10.1073/pnas.1220921110

PMCID:: PMC3696769

Abstract Article PDF–804K

Select item 369682313.

FIGNL1-containing protein complex is required for efficient homologous recombination repair

Jingsong Yuan, Junjie Chen

Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10640–10645. Published online 2013 Jun 10. doi: 10.1073/pnas.1220662110

PMCID:: PMC3696823

Abstract Article PDF–1.0M

Select item 603073014.

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

Julia Hülsmann, Bojana Kravic, Matthias Weith, Matthias Gstaiger, Ruedi Aebersold, Ben C. Collins, Hemmo Meyer

Mol Cell Proteomics. 2018 Jul; 17(7): 1295–1307. Published online 2018 Mar 29. doi: 10.1074/mcp.RA117.000471

PMCID:: PMC6030730

Abstract Article PDF–3.8M

Select item 329955115.

Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci

Andre Franke, Dermot P.B. McGovern, Jeffrey C. Barrett, Kai Wang, Graham L. Radford-Smith, Tariq Ahmad, Charlie W. Lees, Tobias Balschun, James Lee, Rebecca Roberts, Carl A. Anderson, Joshua C. Bis, Suzanne Bumpstead, David Ellinghaus, Eleonora M. Festen, Michel Georges, Talin Haritunians, Luke Jostins, Anna Latiano, Christopher G. Mathew, Grant W. Montgomery, Natalie J. Prescott, Jerome I. Rotter, Philip Schumm, Yashoda Sharma, Lisa A. Simms, Kent D. Taylor, David Whiteman, Cisca Wijmenga, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Buning, Albert Cohen, Jean-Frederick Colombel, Mario Cottone, Laura Stronati, Ted Denson, Martine De Vos, Renata D’Inca, Marla Dubinsky, Cathryn Edwards, Tim Florin, Denis Franchimont, Richard Gearry, Jürgen Glas, Andre Van Gossum, Stephen L. Guthery, Jonas Halfvarson, Daan Hommes, Jean-Pierre Hugot, Debby Laukens, Ian Lawrance, Marc Lemann, Arie Levine, Cecile Libioulle, Edouard Louis, Craig Mowat, William Newman, Julián Panés, Anne Phillips, Deborah D. Proctor, Miguel Regueiro, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Frank Seibold, A. Hillary Steinhart, Pieter C.F. Stokkers, Leif Torkvist, Gerd Kullak Ublick, Soumya Raychaudhuri, Todd Green, Thomas Walters, Stephan R. Targan, Steven R. Brant, John D. Rioux, Mauro D’Amato, Rinse Weersma, Subra Kugathasan, Anne M. Griffiths, John C. Mansfield, Severine Vermeire, Richard H. Duerr, Mark S. Silverberg, Jack Satsangi, Stefan Schreiber, Judy H. Cho, Vito Annese, Hakon Hakonarson, Mark J. Daly, Miles Parkes

Nat Genet. Author manuscript; available in PMC 2012 Mar 12.

Published in final edited form as: Nat Genet. 2010 Dec; 42(12): 1118–1125. doi: 10.1038/ng.717

PMCID:: PMC3299551

Article PDF–864K

Select item 488286716.

Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt, Jean-Claude Twizere

BMC Cancer. 2016; 16: 335. Published online 2016 May 26. doi: 10.1186/s12885-016-2374-2

PMCID:: PMC4882867

Abstract Article PDF–1.8M

Select item 288296117.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 796055018.

USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

Megan Perry, Meghan Biegert, Sai Sundeep Kollala, Halle Mallard, Grace Su, Manohar Kodavati, Natasha Kreiling, Alexander Holbrook, Gargi Ghosal

J Biol Chem. 2021 Jan-Jun; 296: 100396. Published online 2021 Feb 7. doi: 10.1016/j.jbc.2021.100396

PMCID:: PMC7960550

Abstract Article PDF–1.5M

Select item 976969819.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 1056587620.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

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