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Select item 71275931.

NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release

Jude Juventus Aweya, Ching Wooen Sze, Anthony Bayega, Nur Khairiah Mohd-Ismail, Lin Deng, Hak Hotta, Yee-Joo Tan

Virology. 2015 Jan 1; 474: 41–51. Published online 2014 Nov 13. doi: 10.1016/j.virol.2014.10.027

PMCID:: PMC7127593

Abstract Article PDF–680K

Select item 50780932.

The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (Bik) is prognostic for unfavorable outcomes in breast cancer

Vrajesh Pandya, Darryl Glubrecht, Larissa Vos, John Hanson, Sambasivarao Damaraju, John Mackey, Judith Hugh, Ing Swie Goping

Oncotarget. 2016 May 31; 7(22): 33272–33285. Published online 2016 Apr 22. doi: 10.18632/oncotarget.8924

PMCID:: PMC5078093

Abstract Article PDF–6.0M

Select item 39569153.

BikDDA, a Mutant of Bik with Longer Half-Life Expression Protein, Can Be a Novel Therapeutic Gene for Triple-Negative Breast Cancer

Shiping Jiao, Minqing Wu, Feng Ye, Hailin Tang, Xinhua Xie, Xiaoming Xie

PLoS One. 2014; 9(3): e92172. Published online 2014 Mar 17. doi: 10.1371/journal.pone.0092172

PMCID:: PMC3956915

Abstract Article PDF–1.6M

Select item 30086084.

BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma

L Bodet, E Ménoret, G Descamps, C Pellat-Deceunynck, R Bataille, S Le Gouill, P Moreau, M Amiot, P Gomez-Bougie

Br J Cancer. 2010 Dec 7; 103(12): 1808–1814. Published online 2010 Nov 9. doi: 10.1038/sj.bjc.6605981

PMCID:: PMC3008608

Abstract Article PDF–505K

Select item 29285625.

BIK-the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes

G. Chinnadurai, S. Vijayalingam, Ramachandran Rashmi

Oncogene. Author manuscript; available in PMC 2010 Aug 26.

Published in final edited form as: Oncogene. 2008 Dec; 27(Suppl 1): S20–S29. doi: 10.1038/onc.2009.40

PMCID:: PMC2928562

Abstract Article PDF–653K

Select item 13511166.

Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors

Hongbo Zhu, Lidong Zhang, Fengqin Dong, Wei Guo, Shuhong Wu, Fuminori Teraishi, John J. Davis, Paul J. Chiao, Bingliang Fang

Oncogene. Author manuscript; available in PMC 2006 Jan 25.

Published in final edited form as: Oncogene. 2005 Jul 21; 24(31): 4993–4999. doi: 10.1038/sj.onc.1208683

PMCID:: PMC1351116

Abstract Article PDF–847K

Select item 11982227.

A molecular analysis by gene expression profiling reveals Bik/NBK overexpression in sporadic breast tumor samples of Mexican females

Normand García, Fabio Salamanca, Horacio Astudillo-de la Vega, Everardo Curiel-Quesada, Isabel Alvarado, Rosenda Peñaloza, Diego Arenas

BMC Cancer. 2005; 5: 93. Published online 2005 Aug 1. doi: 10.1186/1471-2407-5-93

PMCID:: PMC1198222

Abstract Article PDF–495K

Select item 3569548.

The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis

Jingyung Hur, Jessica Chesnes, Kathryn R. Coser, Roseanna S. Lee, Peter Geck, Kurt J. Isselbacher, Toshi Shioda

Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8): 2351–2356. Published online 2004 Feb 12. doi: 10.1073/pnas.0307337101

PMCID:: PMC356954

Abstract Article PDF–554K

Select item 2315879.

Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K.

J Han, P Sabbatini, E White

Mol Cell Biol. 1996 Oct; 16(10): 5857–5864. doi: 10.1128/mcb.16.10.5857

PMCID:: PMC231587

Summary PDF–4.1M

Select item 886620710.

Casein Kinase II Activates Bik to Induce Death of Hyperplastic Mucous Cells in a Cell Cycle-dependent Manner

Yohannes A. Mebratu, Jewel Imani, Jane T. Jones, Yohannes Tesfaigzi

J Cell Physiol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: J Cell Physiol. 2022 Feb; 237(2): 1561–1572. Published online 2021 Nov 6. doi: 10.1002/jcp.30630

PMCID:: PMC8866207

Abstract Article PDF–1.6M

Select item 555212911.

Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells

Ozgur Kutuk, Nurgul Aytan, Bahriye Karakas, Asli Giray Kurt, Ufuk Acikbas, Sehime Gulsun Temel, Huveyda Basaga

PLoS One. 2017; 12(8): e0182809. Published online 2017 Aug 10. doi: 10.1371/journal.pone.0182809

PMCID:: PMC5552129

Abstract Article PDF–7.8M

Select item 114256412.

Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis

Marc Germain, Jaigi P Mathai, Heidi M McBride, Gordon C Shore

EMBO J. 2005 Apr 20; 24(8): 1546–1556. Published online 2005 Mar 24. doi: 10.1038/sj.emboj.7600592

PMCID:: PMC1142564

Abstract Article PDF–378K

Select item 874523613.

RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival

Kenzui Taniue, Tanzina Tanu, Yuki Shimoura, Shuhei Mitsutomi, Han Han, Rika Kakisaka, Yusuke Ono, Nobue Tamamura, Kenji Takahashi, Youichiro Wada, Yusuke Mizukami, Nobuyoshi Akimitsu

Int J Mol Sci. 2022 Jan; 23(1): 496. Published online 2022 Jan 2. doi: 10.3390/ijms23010496

PMCID:: PMC8745236

Abstract Article PDF–6.0M

Select item 567579914.

Blocking Bcl-2 Resolves IL-13–Mediated Mucous Cell Hyperplasia in a Bik-Dependent Manner

Hitendra S. Chand, Yohannes A. Mebratu, Philip J. Kuehl, Yohannes Tesfaigzi

J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: J Allergy Clin Immunol. 2017 Nov; 140(5): 1456–1459.e9. Published online 2017 Aug 4. doi: 10.1016/j.jaci.2017.05.038

PMCID:: PMC5675799

Abstract Article PDF–485K

Select item 534840515.

LncRNA H19 confers chemoresistance in ERα-positive breast cancer through epigenetic silencing of the pro-apoptotic gene BIK

Xinxin Si, Ruochen Zang, Erbao Zhang, Yue Liu, Xiao Shi, Ershao Zhang, Lipei Shao, Andi Li, Nan Yang, Xiao Han, Beijing Pan, Zhihong Zhang, Luan Sun, Yujie Sun

Oncotarget. 2016 Dec 6; 7(49): 81452–81462. Published online 2016 Nov 10. doi: 10.18632/oncotarget.13263

PMCID:: PMC5348405

Abstract Article PDF–8.6M

Select item 399382316.

Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Barr Virus Antagonizes Transforming Growth Factor β1-Induced B-Cell Apoptosis

Eva M. Campion, Roya Hakimjavadi, Sinéad T. Loughran, Susan Phelan, Sinéad M. Smith, Brendan N. D'Souza, Rosemary J. Tierney, Andrew I. Bell, Paul A. Cahill, Dermot Walls

J Virol. 2014 May; 88(9): 5001–5013. doi: 10.1128/JVI.03642-13

PMCID:: PMC3993823

Abstract Article PDF–1.8M

Select item 327114317.

Genetic Determinants for Promoter Hypermethylation in the Lungs of Smokers: A Candidate Gene-Based Study

Shuguang Leng, Christine A. Stidley, Yushi Liu, Christopher K. Edlund, Randall P. Willink, Younghun Han, Maria Teresa Landi, Michael Thun, Maria A. Picchi, Shannon E. Bruse, Richard E. Crowell, David Van Den Berg, Neil E. Caporaso, Christopher I. Amos, Jill M. Siegfried, Yohannes Tesfaigzi, Frank D. Gilliland, Steven A. Belinsky

Cancer Res. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Cancer Res. 2012 Feb 1; 72(3): 707–715. Published online 2011 Dec 2. doi: 10.1158/0008-5472.CAN-11-3194

PMCID:: PMC3271143

Abstract Article PDF–374K

Select item 313829818.

Novel Mechanism of Anti-apoptotic Function of 78-kDa Glucose-regulated Protein (GRP78): ENDOCRINE RESISTANCE FACTOR IN BREAST CANCER, THROUGH RELEASE OF B-CELL LYMPHOMA 2 (BCL-2) FROM BCL-2-INTERACTING KILLER (BIK)

Hui Zhou, Yi Zhang, Yong Fu, Lauren Chan, Amy S. Lee

J Biol Chem. 2011 Jul 22; 286(29): 25687–25696. Published online 2011 May 26. doi: 10.1074/jbc.M110.212944

PMCID:: PMC3138298

Abstract Article PDF–3.8M

Select item 106496719.

Degradation of the Proapoptotic Proteins Bik, Puma, and Bim with Bcl-2 Domain 3 Homology in Chlamydia trachomatis-Infected Cells

Feng Dong, Mustak Pirbhai, Yangming Xiao, Youmin Zhong, Yimou Wu, Guangming Zhong

Infect Immun. 2005 Mar; 73(3): 1861–1864. doi: 10.1128/IAI.73.3.1861-1864.2005

Correction in:: Infect Immun. 2005 Jul; 73(7): 4459.

PMCID:: PMC1064967

Abstract Article PDF–171K

Select item 10887520.

Interaction of an Adenovirus E3 14.7-Kilodalton Protein with a Novel Tumor Necrosis Factor Alpha-Inducible Cellular Protein Containing Leucine Zipper Domains

Yongan Li, Jian Kang, Marshall S. Horwitz

Mol Cell Biol. 1998 Mar; 18(3): 1601–1610. doi: 10.1128/mcb.18.3.1601

PMCID:: PMC108875

Abstract Article PDF–2.9M

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PMC Links for Gene (Select 638) (60)
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Chlamydomonas reinhardtii strain CC-503 chloroplast thioredoxin peroxidase (PRX1) gene, partial cds; nuclear gene for chloroplast product
gi|294845939|gb|GU735469.1|

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Volvox protein kinase (PRP4) gene, partial cds.
Volvox protein kinase (PRP4) gene, partial cds.
PopSet: 294845901

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Eptesicus
Eptesicus
Transcriptome analysis and small RNA analysis of poly (I:C)-treated Eptesicus bat cells

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