PMC Links for Gene (Select 6197) - PMC

Lingtao Jin, Dan Li, Jong Seok Lee, Shannon Elf, Gina N. Alesi, Jun Fan, Hee-Bum Kang, Dongsheng Wang, Haian Fu, Jack Taunton, Titus J. Boggon, Meghan Tucker, Ting-Lei Gu, Zhuo G. Chen, Dong M. Shin, Fadlo R. Khuri, Sumin Kang

Mol Cell Biol. 2013 Jul; 33(13): 2574–2585. doi: 10.1128/MCB.01677-12

PMCID:: PMC3700113

Abstract Article PDF–2.8M

Select item 36833716.

The unusual mechanism of inhibition of the p90 ribosomal S6 kinase (RSK) by flavonol rhamnosides

Darkhan Utepbergenov, Zygmunt S. Derewenda

Biochim Biophys Acta. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Jul; 1834(7): 1285–1291. Published online 2013 Mar 27. doi: 10.1016/j.bbapap.2013.03.018

PMCID:: PMC3683371

Abstract Article PDF–1.6M

Select item 36418347.

Structural Bioinformatics-Based Design of Selective, Irreversible Kinase Inhibitors

Michael S. Cohen, Chao Zhang, Kevan M. Shokat, Jack Taunton

Science. Author manuscript; available in PMC 2013 May 2.

Published in final edited form as: Science. 2005 May 27; 308(5726): 1318–1321. doi: 10.1126/science1108367

PMCID:: PMC3641834

Abstract Article PDF–1.4M

Select item 35279308.

RSK2 Protein Suppresses Integrin Activation and Fibronectin Matrix Assembly and Promotes Cell Migration

Joanna E. Gawecka, Shirley S. Young-Robbins, Florian J. Sulzmaier, Maisel J. Caliva, Minna M. Heikkilä, Michelle L. Matter, Joe W. Ramos

J Biol Chem. 2012 Dec 21; 287(52): 43424–43437. Published online 2012 Nov 1. doi: 10.1074/jbc.M112.423046

PMCID:: PMC3527930

Abstract Article PDF–4.2M

Select item 35107339.

RSK2 as a key regulator in human skin cancer

Yong-Yeon Cho, Mee-Hyun Lee, Cheol-Jung Lee, Ke Yao, Hye Suk Lee, Ann M. Bode, Zigang Dong

Carcinogenesis. 2012 Dec; 33(12): 2529–2537. Published online 2012 Aug 24. doi: 10.1093/carcin/bgs271

PMCID:: PMC3510733

Abstract Article PDF–4.7M

Select item 305524410.

Altered neurodevelopment associated with mutations of RSK2: a morphometric MRI study of Coffin–Lowry syndrome

Shelli R. Kesler, Richard J. Simensen, Kytja Voeller, Fatima Abidi, Roger E. Stevenson, Charles E. Schwartz, Allan L. Reiss

Neurogenetics. Author manuscript; available in PMC 2011 Mar 11.

Published in final edited form as: Neurogenetics. 2007 Apr; 8(2): 143–147. Published online 2007 Feb 22. doi: 10.1007/s10048-007-0080-6

PMCID:: PMC3055244

Abstract Article PDF–422K

Select item 284605011.

p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells

Sumin Kang, Shannon Elf, Katherine Lythgoe, Taro Hitosugi, Jack Taunton, Wei Zhou, Li Xiong, Dongsheng Wang, Susan Muller, Songqing Fan, Shi-Yong Sun, Adam I. Marcus, Ting-Lei Gu, Roberto D. Polakiewicz, Zhuo (Georgia) Chen, Fadlo R. Khuri, Dong M. Shin, Jing Chen

J Clin Invest. 2010 Apr 1; 120(4): 1165–1177. Published online 2010 Mar 15. doi: 10.1172/JCI40582

PMCID:: PMC2846050

Abstract Article PDF–2.6M

Select item 282265412.

A Regulatory Mechanism for RSK2 NH₂-Terminal Kinase Activity

Yong-Yeon Cho, Ke Yao, Angelo Pugliese, Margarita L. Malakhova, Ann M. Bode, Zigang Dong

Cancer Res. Author manuscript; available in PMC 2010 May 15.

Published in final edited form as: Cancer Res. 2009 May 15; 69(10): 4398–4406. Published online 2009 May 12. doi: 10.1158/0008-5472.CAN-08-4959

PMCID:: PMC2822654

Abstract Article PDF–1.2M

Select item 271497313.

Mutations in the RSK2(RPS6KA3) gene cause Coffin–Lowry syndrome and nonsyndromic X-linked mental retardation

M Field, P Tarpey, J Boyle, S Edkins, J Goodship, Y Luo, J Moon, J Teague, MR Stratton, PA Futreal, R Wooster, FL Raymond, G Turner

Clin Genet. Author manuscript; available in PMC 2009 Jul 24.

Published in final edited form as: Clin Genet. 2006 Dec; 70(6): 509–515. doi: 10.1111/j.1399-0004.2006.00723.x

PMCID:: PMC2714973

Abstract Article PDF–551K

Select item 264828114.

Mitogen-Activated Protein Kinase-Activated Kinase RSK2 Plays a Role in Innate Immune Responses to Influenza Virus Infection

Satoshi Kakugawa, Masayuki Shimojima, Hideo Goto, Taisuke Horimoto, Naoki Oshimori, Gabriele Neumann, Tadashi Yamamoto, Yoshihiro Kawaoka

J Virol. 2009 Mar; 83(6): 2510–2517. Published online 2009 Jan 7. doi: 10.1128/JVI.02416-08

PMCID:: PMC2648281

Abstract Article PDF–462K

Select item 173423215.

Unreported RSK2 missense mutation in two male sibs with an unusually mild form of Coffin-Lowry syndrome

S Manouvrier-Hanu, J Amiel, S Jacquot, K Merienne, A Moerman, A Coeslier, F Labarriere, L Vallee, M Croquette, A Hanauer

J Med Genet. 1999 Oct; 36(10): 775–778. doi: 10.1136/jmg.36.10.775

PMCID:: PMC1734232

Summary PDF–77K

Select item 137763416.

Mutation analysis of the RSK2 gene in Coffin-Lowry patients: extensive allelic heterogeneity and a high rate of de novo mutations.

S Jacquot, K Merienne, D De Cesare, S Pannetier, J L Mandel, P Sassone-Corsi, A Hanauer

Am J Hum Genet. 1998 Dec; 63(6): 1631–1640. doi: 10.1086/302153

PMCID:: PMC1377634

Summary PDF–233K

Select item 37912917.

Unusual Splice-Site Mutations in the RSK2 Gene and Suggestion of Genetic Heterogeneity in Coffin-Lowry Syndrome

Maria Zeniou, Solange Pannetier, Jean-Pierre Fryns, André Hanauer

Am J Hum Genet. 2002 Jun; 70(6): 1421–1433. Published online 2002 Apr 25. doi: 10.1086/340607

PMCID:: PMC379129

Abstract Article PDF–657K

Select item 37340618.

Delineation of the mechanisms of aberrant splicing caused by two unusual intronic mutations in the RSK2 gene involved in Coffin–Lowry syndrome

Maria Zeniou, Renata Gattoni, André Hanauer, James Stévenin

Nucleic Acids Res. 2004; 32(3): 1214–1223. Published online 2004 Feb 18. doi: 10.1093/nar/gkh272

PMCID:: PMC373406

Abstract Article PDF–348K

Select item 1024855319.

The ribosomal S6 kinase 2 (RSK2)–SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling

Jocelyne Lopez, Daniel A. Bonsor, Matthew J. Sale, Anatoly Urisman, Jennifer L. Mehalko, Miranda Cabanski-Dunning, Pau Castel, Dhirendra K. Simanshu, Frank McCormick

J Biol Chem. 2023 Jun; 299(6): 104789. Published online 2023 May 5. doi: 10.1016/j.jbc.2023.104789

PMCID:: PMC10248553

Abstract Article PDF–3.1M

Select item 901191920.

ERα-mediated nuclear sequestration of RSK2 is required for ER+ breast cancer tumorigenesis

Katarzyna A. Ludwik, Oliver G. McDonald, David R. Brenin, Deborah A. Lannigan

Cancer Res. Author manuscript; available in PMC 2022 Apr 15.

Published in final edited form as: Cancer Res. 2018 Apr 15; 78(8): 2014–2025. Published online 2018 Jan 19. doi: 10.1158/0008-5472.CAN-17-2063

PMCID:: PMC9011919

Abstract Article PDF–3.4M

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PMC Links for Gene (Select 6197) (128)
PMC
PREDICTED: Branchiostoma floridae exocyst complex component 8-like (LOC118431191...
PREDICTED: Branchiostoma floridae exocyst complex component 8-like (LOC118431191), transcript variant X1, mRNA
gi|1889933099|ref|XM_035842322.1|

Nucleotide
ribosomal protein S6 kinase alpha-3 isoform X3 [Homo sapiens]
ribosomal protein S6 kinase alpha-3 isoform X3 [Homo sapiens]
gi|2217393515|ref|XP_047298288.1|

Protein
PREDICTED: Homo sapiens ribosomal protein S6 kinase A3 (RPS6KA3), transcript var...
PREDICTED: Homo sapiens ribosomal protein S6 kinase A3 (RPS6KA3), transcript variant X7, mRNA
gi|2217393520|ref|XM_011545560.2|

Nucleotide
PREDICTED: Branchiostoma floridae activated Cdc42 kinase-like (LOC118431189), tr...
PREDICTED: Branchiostoma floridae activated Cdc42 kinase-like (LOC118431189), transcript variant X7, mRNA
gi|1889933081|ref|XM_035842312.1|

Nucleotide

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