PMC Links for Gene (Select 6016) - PMC

Links from Gene

Items: 1 to 20 of 35

<< First< Prev

Page of 2

Select item 88488601.

Multiomics characterization of oncogenic signaling mediated by wild-type and mutant RIT1

April Lo, Kristin Holmes, Shriya Kamlapurkar, Filip Mundt, Sitapriya Moorthi, Iris Fung, Shaunt Fereshetian, Jacqueline Watson, Steven A. Carr, Philipp Mertins, Alice H. Berger

Sci Signal. Author manuscript; available in PMC 2022 May 30.

Published in final edited form as: Sci Signal. 2021 Nov 30; 14(711): eabc4520. Published online 2021 Nov 30. doi: 10.1126/scisignal.abc4520

PMCID:: PMC8848860

Abstract Article PDF–1.7M

Select item 87111272.

Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies

I Gómez-Seguí, H Makishima, A Jerez, K Yoshida, B Przychodzen, S Miyano, Y Shiraishi, HD Husseinzadeh, K Guinta, M Clemente, N Hosono, MA McDevitt, AR Moliterno, MA Sekeres, S Ogawa, JP Maciejewski

Leukemia. Author manuscript; available in PMC 2021 Dec 27.

Published in final edited form as: Leukemia. 2013 Sep; 27(9): 1943–1946. Published online 2013 Jun 14. doi: 10.1038/leu.2013.179

PMCID:: PMC8711127

Article PDF–639K

Select item 77870543.

The molecular functions of RIT1 and its contribution to human disease

Richard Van, Antonio Cuevas-Navarro, Pau Castel, Frank McCormick

Biochem J. Author manuscript; available in PMC 2021 Aug 14.

Published in final edited form as: Biochem J. 2020 Aug 14; 477(15): 2755–2770. doi: 10.1042/BCJ20200442

PMCID:: PMC7787054

Abstract Article PDF–1.5M

Select item 49570484.

Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1)

Zhenhao Fang, Christopher B. Marshall, Jiani C. Yin, Mohammad T. Mazhab-Jafari, Geneviève M. C. Gasmi-Seabrook, Matthew J. Smith, Tadateru Nishikawa, Yang Xu, Benjamin G. Neel, Mitsuhiko Ikura

J Biol Chem. 2016 Jul 22; 291(30): 15641–15652. Published online 2016 May 18. doi: 10.1074/jbc.M116.714196

PMCID:: PMC4957048

Abstract Article PDF–1.3M

Select item 47606895.

Mutations in RIT1 cause Noonan syndrome – additional functional evidence and expanding the clinical phenotype

Martin Koenighofer, Christina Y. Hung, Jacob L. McCauley, Julia Dallman, Emma J. Back, Ivana Mihalek, Karen W. Gripp, Katia Sol-Church, Paolo Rusconi, Zhaiyi Zhang, Geng-Xian Shi, Douglas A. Andres, Olaf A. Bodamer

Clin Genet. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Clin Genet. 2016 Mar; 89(3): 359–366. Published online 2015 Jun 4. doi: 10.1111/cge.12608

PMCID:: PMC4760689

Abstract Article PDF–1000K

Select item 46375546.

Elevated expression of RIT1 correlates with poor prognosis in endometrial cancer

Fengjuan Xu, Su’an Sun, Shilan Yan, Hongling Guo, Miao Dai, Yincheng Teng

Int J Clin Exp Pathol. 2015; 8(9): 10315–10324. Published online 2015 Sep 1.

PMCID:: PMC4637554

Abstract Article PDF–1.5M

Select item 41509887.

Oncogenic RIT1 mutations in lung adenocarcinoma

A H Berger, M Imielinski, F Duke, J Wala, N Kaplan, G-X Shi, D A Andres, M Meyerson

Oncogene. 2014; 33(35): 4418–4423. Published online 2014 Jan 27. doi: 10.1038/onc.2013.581

Correction in:: Oncogene. 2022; 41(19): 2788.

PMCID:: PMC4150988

Abstract Article PDF–1.8M

Select item 37740118.

Rit Subfamily Small GTPases: Regulators in Neuronal Differentiation and Survival

Geng-Xian Shi, Weikang Cai, Douglas A. Andres

Cell Signal. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Cell Signal. 2013 Oct; 25(10): 2060–2068. Published online 2013 Jun 11. doi: 10.1016/j.cellsig.2013.06.002

PMCID:: PMC3774011

Abstract Article PDF–1.6M

Select item 36485639.

Knockdown of Regulator of Cullins-1 (ROC1) Expression Induces Bladder Cancer Cell Cycle Arrest at the G2 Phase and Senescence

Wei Wang, Zhihong Liu, Ping Qu, Zhengdong Zhou, Yigang Zeng, Jie Fan, Yong Liu, Yifeng Guo, Jianxin Qiu

PLoS One. 2013; 8(5): e62734. Published online 2013 May 8. doi: 10.1371/journal.pone.0062734

PMCID:: PMC3648563

Abstract Article PDF–14M

Select item 313335110.

A Rit GTPase-p38 Mitogen-Activated Protein Kinase Survival Pathway Confers Resistance to Cellular Stress

Geng-Xian Shi, Ling Jin, Douglas A. Andres

Mol Cell Biol. 2011 May; 31(10): 1938–1948. doi: 10.1128/MCB.01380-10

PMCID:: PMC3133351

Abstract Article PDF–3.1M

Select item 1068560711.

RIT1 regulates mitosis and promotes proliferation by interacting with SMC3 and PDS5 in hepatocellular carcinoma

Yang Su, Hechun Lin, Junming Yu, Lin Mao, Wenjiao Jin, Tengfei Liu, Shuqing Jiang, Yunyu Wu, Saihua Zhang, Qin Geng, Chao Ge, Fangyu Zhao, Taoyang Chen, Ying Cui, Jinjun Li, Helei Hou, Xinli Zhou, Hong Li

J Exp Clin Cancer Res. 2023; 42: 326. Published online 2023 Nov 29. doi: 10.1186/s13046-023-02892-x

PMCID:: PMC10685607

Abstract Article PDF–14M

Select item 619727912.

RIT1 suppresses esophageal squamous cell carcinoma growth and metastasis and predicts good prognosis

Yan-Fen Feng, Yi-Yan Lei, Jia-Bin Lu, Shao-Yan Xi, Yu Zhang, Qi-Tao Huang, Qiu-Liang Wu, Fang Wang

Cell Death Dis. 2018 Nov; 9(11): 1085. Published online 2018 Oct 22. doi: 10.1038/s41419-018-0979-x

PMCID:: PMC6197279

Abstract Article PDF–2.8M

Select item 497068713.

Mutations in RIT1 cause Noonan syndrome with possible juvenile myelomonocytic leukemia but are not involved in acute lymphoblastic leukemia

Hélène Cavé, Aurélie Caye, Nehla Ghedira, Yline Capri, Nathalie Pouvreau, Natacha Fillot, Aurélien Trimouille, Cédric Vignal, Odile Fenneteau, Yves Alembik, Jean-Luc Alessandri, Patricia Blanchet, Odile Boute, Patrice Bouvagnet, Albert David, Anne Dieux Coeslier, Bérénice Doray, Olivier Dulac, Valérie Drouin-Garraud, Marion Gérard, Delphine Héron, Bertrand Isidor, Didier Lacombe, Stanislas Lyonnet, Laurence Perrin, Marlène Rio, Joëlle Roume, Sylvie Sauvion, Annick Toutain, Catherine Vincent-Delorme, Marjorie Willems, Clarisse Baumann, Alain Verloes

Eur J Hum Genet. 2016 Aug; 24(8): 1124–1131. Published online 2016 Jan 13. doi: 10.1038/ejhg.2015.273

PMCID:: PMC4970687

Abstract Article PDF–1.4M

Select item 351359314.

Rit GTPase Regulates a p38 MAPK-Dependent Neuronal Survival Pathway

Weikang Cai, Jennifer L. Rudolph, Tomoko Sengoku, Douglas A. Andres

Neurosci Lett. Author manuscript; available in PMC 2013 Dec 7.

Published in final edited form as: Neurosci Lett. 2012 Dec 7; 531(2): 125–130. Published online 2012 Nov 2. doi: 10.1016/j.neulet.2012.10.036

PMCID:: PMC3513593

Abstract Article PDF–1.5M

Select item 371076715.

Gain-of-Function Mutations in RIT1 Cause Noonan Syndrome, a RAS/MAPK Pathway Syndrome

Yoko Aoki, Tetsuya Niihori, Toshihiro Banjo, Nobuhiko Okamoto, Seiji Mizuno, Kenji Kurosawa, Tsutomu Ogata, Fumio Takada, Michihiro Yano, Toru Ando, Tadataka Hoshika, Christopher Barnett, Hirofumi Ohashi, Hiroshi Kawame, Tomonobu Hasegawa, Takahiro Okutani, Tatsuo Nagashima, Satoshi Hasegawa, Ryo Funayama, Takeshi Nagashima, Keiko Nakayama, Shin-ichi Inoue, Yusuke Watanabe, Toshihiko Ogura, Yoichi Matsubara

Am J Hum Genet. 2013 Jul 11; 93(1): 173–180. doi: 10.1016/j.ajhg.2013.05.021

PMCID:: PMC3710767

Abstract Article PDF–913K

Select item 579923616.

Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies

Gordon K. C. Leung, H. M. Luk, Vincent H. M. Tang, W. W. Gao, Christopher C. Y. Mak, Mullin H. C. Yu, W. L. Wong, Yoyo W. Y. Chu, W. L. Yang, Wilfred H. S. Wong, Alvin C. H. Ma, Anskar Y. H. Leung, D. Y. Jin, Kelvin Y. K. Chan, Judith Allanson, Ivan F. M. Lo, Brian H. Y. Chung

Sci Rep. 2018; 8: 2421. Published online 2018 Feb 5. doi: 10.1038/s41598-018-20894-0

PMCID:: PMC5799236

Abstract Article PDF–2.9M

Select item 54342217.

Rit Contributes to Nerve Growth Factor-Induced Neuronal Differentiation via Activation of B-Raf-Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Cascades

Geng-Xian Shi, Douglas A. Andres

Mol Cell Biol. 2005 Jan; 25(2): 830–846. doi: 10.1128/MCB.25.2.830-846.2005

PMCID:: PMC543422

Abstract Article PDF–773K

Select item 593773718.

RIT1 controls actin dynamics via complex formation with RAC1/CDC42 and PAK1

Uta Meyer zum Büschenfelde, Laura Isabel Brandenstein, Leonie von Elsner, Kristina Flato, Tess Holling, Martin Zenker, Georg Rosenberger, Kerstin Kutsche

PLoS Genet. 2018 May; 14(5): e1007370. Published online 2018 May 7. doi: 10.1371/journal.pgen.1007370

PMCID:: PMC5937737

Abstract Article PDF–29M

Select item 350105019.

Rit-mediated Stress Resistance Involves a p38-Mitogen- and Stress-activated Protein Kinase 1 (MSK1)-dependent cAMP Response Element-binding Protein (CREB) Activation Cascade

Geng-Xian Shi, Weikang Cai, Douglas A. Andres

J Biol Chem. 2012 Nov 16; 287(47): 39859–39868. Published online 2012 Oct 4. doi: 10.1074/jbc.M112.384248

PMCID:: PMC3501050

Abstract Article PDF–3.6M

Select item 657925920.

Rin, a Neuron-Specific and Calmodulin-Binding Small G-Protein, and Rit Define a Novel Subfamily of Ras Proteins

Ching-Hsien J. Lee, Neil G. Della, Christina E. Chew, Donald J. Zack

J Neurosci. 1996 Nov 1; 16(21): 6784–6794. doi: 10.1523/JNEUROSCI.16-21-06784.1996

PMCID:: PMC6579259

Abstract Article

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 35

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity