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Items: 1 to 20 of 124

1.
A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells
Lucia Mercedes Ruiz-Perera, Johannes Friedrich Wilhelm Greiner, Christian Kaltschmidt, Barbara Kaltschmidt
Cells. 2020 Apr; 9(4): 1037. Published online 2020 Apr 22. doi: 10.3390/cells9041037
PMCID:
PMC7226153
AbstractArticlePDF–7.3M
2.
Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models
Zishan Wang, Hongtian Dong, Jinghui Wang, Yulu Huang, Xiaoshuang Zhang, Yilin Tang, Qing Li, Zhaolin Liu, Yuanyuan Ma, Jiabin Tong, Li Huang, Jian Fei, Mei Yu, Jian Wang, Fang Huang
Redox Biol. 2020 Feb; 30: 101427. Published online 2020 Jan 13. doi: 10.1016/j.redox.2020.101427
PMCID:
PMC6994410
AbstractArticlePDF–3.9M
3.
Combined immunodeficiency in a patient with deficiency of c-Rel
Sarah Beaussant-Cohen, Faris Jaber, Michel J. Massaad, Sabrina Weeks, Jennifer Jones, Mohammed F. Alosaimi, Jacqueline Wallace, Waleed Al-Herz, Raif S. Geha, Janet Chou
J Allergy Clin Immunol. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2019 Aug; 144(2): 606–608.e4. Published online 2019 May 16. doi: 10.1016/j.jaci.2019.05.003
PMCID:
PMC6688935
AbstractArticlePDF–781K
4.
CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle
Carsten Slotta, Thomas Schlüter, Lucia M. Ruiz-Perera, Hussamadin M. Kadhim, Tobias Tertel, Elena Henkel, Wolfgang Hübner, Johannes F. W. Greiner, Thomas Huser, Barbara Kaltschmidt, Christian Kaltschmidt
PLoS One. 2017; 12(8): e0182373. Published online 2017 Aug 2. doi: 10.1371/journal.pone.0182373
PMCID:
PMC5540532
AbstractArticlePDF–10M
5.
Association of rheumatoid arthritis susceptibility gene with lipid profiles in patients with rheumatoid arthritis
Lisa A. Davis, Emily Whitfield, Grant W. Cannon, Roger K. Wolff, Dannette S. Johnson, Andreas M. Reimold, Gail S. Kerr, J. Steuart Richards, Ted R. Mikuls, Liron Caplan
Rheumatology (Oxford) 2014 Jun; 53(6): 1014–1021. Published online 2014 Jan 31. doi: 10.1093/rheumatology/ket472
PMCID:
PMC4023559
AbstractArticlePDF–148K
6.
A small molecule c-Rel inhibitor reduces alloactivation of T-cells without compromising anti-tumor activity
Yusuke Shono, Andrea Z Tuckett, Samedy Ouk, Hsiou-Chi Liou, Grégoire Altan-Bonnet, Jennifer J Tsai, Jennifer E Oyler, Odette M Smith, Mallory L West, Natalie V Singer, Ekaterina Doubrovina, Dmitry Pankov, Chandresh V Undhad, George F Murphy, Cecilia Lezcano, Chen Liu, Richard J O’Reilly, Marcel RM van den Brink, Johannes L Zakrzewski
Cancer Discov. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: Cancer Discov. 2014 May; 4(5): 578–591. Published online 2014 Feb 18. doi: 10.1158/2159-8290.CD-13-0585
PMCID:
PMC4011979
AbstractArticlePDF–1.2M
7.
A sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscle
Sophie E. Hussey, Helen Lum, Andrea Alvarez, Yolanda Cipriani, José de Jesús Garduño-Garcia, Luis Anaya, John Dube, Nicolas Musi
Diabetologia. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: Diabetologia. 2014 Mar; 57(3): 582–591. Published online 2013 Dec 14. doi: 10.1007/s00125-013-3111-x
PMCID:
PMC3945433
AbstractArticlePDF–2.7M
8.
Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population
Stephen Eyre, Anne Hinks, Edward Flynn, Paul Martin, Anthony G Wilson, James R Maxwell, Ann W Morgan, Paul Emery, Sophia Steer, Lynne J Hocking, David M Reid, Pille Harrison, Paul Wordsworth, Wendy Thomson, Jane Worthington, Anne Barton
Ann Rheum Dis. 2010 Aug 1; 69(8): 1572–1573. Published online 2010 Aug 1. doi: 10.1136/ard.2009.122887
Correction in:
Ann Rheum Dis. 2011 Aug; 70(8): 1519.
PMCID:
PMC3009391
ArticlePDF–98K
9.
Deletion analysis and alternative splicing define a transactivation inhibitory domain in human oncoprotein REL
JR Leeman, MA Weniger, TF Barth, TD Gilmore
Oncogene. Author manuscript; available in PMC 2010 Mar 5.
Published in final edited form as: Oncogene. 2008 Dec 4; 27(53): 6770–6781. Published online 2008 Aug 11. doi: 10.1038/onc.2008.284
PMCID:
PMC2832920
AbstractArticlePDF–1.5M
10.
Ser484 and Ser494 in REL Are the Major Sites of IKK Phosphorylation In Vitro: Evidence That IKK Does Not Directly Enhance GAL4-REL Transactivation
Michael R. Garbati, Thomas D. Gilmore
Gene Expr. 2008; 14(4): 195–205. Published online 2018 Jul 12. doi: 10.3727/105221608786883807
PMCID:
PMC2822992
AbstractArticlePDF–294K
11.
Genetic characterization of human c-rel sequences.
E Brownell, S J O'Brien, W G Nash, N Rice
Mol Cell Biol. 1985 Oct; 5(10): 2826–2831. doi: 10.1128/mcb.5.10.2826
PMCID:
PMC367021
SummaryPage BrowsePDF–1.0M
12.
The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein.
S Kumar, A B Rabson, C Gélinas
Mol Cell Biol. 1992 Jul; 12(7): 3094–3106. doi: 10.1128/mcb.12.7.3094
PMCID:
PMC364524
SummaryPage BrowsePDF–3.6M
13.
Differential expression of Rel family members in human T-cell leukemia virus type I-infected cells: transcriptional activation of c-rel by Tax protein.
C C Li, F W Ruscetti, N R Rice, E Chen, N S Yang, J Mikovits, D L Longo
J Virol. 1993 Jul; 67(7): 4205–4213. doi: 10.1128/jvi.67.7.4205-4213.1993
PMCID:
PMC237790
SummaryPage BrowsePDF–2.3M
14.
Mutations in the v-Rel Transactivation Domain Indicate Altered Phosphorylation and Identify a Subset of NF-κB-Regulated Cell Death Inhibitors Important for v-Rel Transforming Activity
Béatrice Rayet, Yongjun Fan, Céline Gélinas
Mol Cell Biol. 2003 Mar; 23(5): 1520–1533. doi: 10.1128/MCB.23.5.1520-1533.2003
PMCID:
PMC151695
AbstractArticlePDF–545K
15.
REL and BHLHE40 variants are associated with IL-12 and IL-10 responses and tuberculosis risk
Javeed A. Shah, Alex J. Warr, Andrew D. Graustein, Aparajita Saha, Sarah J. Dunstan, Nguyen T.T. Thuong, Guy E. Thwaites, Maxine Caws, Phan V.K. Thai, Nguyen D. Bang, Tran T.H. Chau, Chiea Chuen Khor, Zheng Li, Martin Hibberd, Xuling Chang, Felicia K. Nguyen, Carlo A. Hernandez, Madison A. Jones, Christopher M. Sassetti, Katherine A. Fitzgerald, Munyaradzi Musvosvi, Anele Gela, Willem A. Hanekom, Mark Hatherill, Thomas J. Scriba, Thomas R. Hawn
J Immunol. Author manuscript; available in PMC 2023 Mar 15.
Published in final edited form as: J Immunol. 2022 Mar 15; 208(6): 1352–1361. Published online 2022 Feb 25. doi: 10.4049/jimmunol.2100671
PMCID:
PMC8917052
AbstractArticlePDF–917K
16.
The c-Rel-c-Myc Axis Controls Metabolism and Proliferation of Human T Leukemia Cells
Xinyuan Li, George Luo, Ting Li, Honghong Sun, Wei Wang, Emily Eiler, Jason R. Goldsmith, Youhai H. Chen
Mol Immunol. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Mol Immunol. 2020 Sep; 125: 115–122. Published online 2020 Jul 10. doi: 10.1016/j.molimm.2020.06.029
PMCID:
PMC7423645
AbstractArticlePDF–894K
17.
A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders
Lakshmi Subramanian, Abrar A. Khan, Prasanna K. R. Allu, Malapaka Kiranmayi, Bhavani S. Sahu, Saurabh Sharma, Madhu Khullar, Ajit S. Mullasari, Nitish R. Mahapatra
J Biol Chem. 2017 Aug 25; 292(34): 13970–13985. Published online 2017 Jun 30. doi: 10.1074/jbc.M117.778134
PMCID:
PMC5572921
AbstractArticlePDF–3.1M
18.
Genetic Variation in the REL Gene Increases Risk of Behcet’s Disease in a Chinese Han Population but That of PRKCQ Does Not
Feilan Chen, Lei Xu, Tingting Zhao, Xiang Xiao, Yongquan Pan, Shengping Hou
PLoS One. 2016; 11(1): e0147350. Published online 2016 Jan 19. doi: 10.1371/journal.pone.0147350
PMCID:
PMC4718718
AbstractArticlePDF–211K
19.
Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma
Ling Li, Zijun Y. Xu-Monette, Chi Young Ok, Alexandar Tzankov, Ganiraju C. Manyam, Ruifan Sun, Carlo Visco, Mingzhi Zhang, Santiago Montes-Moreno, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Michael B. Møller, Jinfeng Wang, Ben M. Parsons, Jane N. Winter, Miguel A. Piris, Lan V. Pham, L. Jeffrey Medeiros, Ken H. Young
Oncotarget. 2015 Sep 15; 6(27): 23157–23180. Published online 2015 Jun 30. doi: 10.18632/oncotarget.4319
PMCID:
PMC4695110
AbstractArticlePDF–6.5M
20.
c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells
C Geismann, F Grohmann, S Sebens, G Wirths, A Dreher, R Häsler, P Rosenstiel, C Hauser, J-H Egberts, A Trauzold, G Schneider, B Sipos, S Zeissig, S Schreiber, H Schäfer, A Arlt
Cell Death Dis. 2014 Oct; 5(10): e1455. Published online 2014 Oct 9. doi: 10.1038/cddis.2014.417
PMCID:
PMC4237244
AbstractArticlePDF–2.7M

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