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Select item 61871741.

Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model

Timokratis Karamitros, Tara Hurst, Emanuele Marchi, Eirini Karamichali, Urania Georgopoulou, Andreas Mentis, Joey Riepsaame, Audrey Lin, Dimitrios Paraskevis, Angelos Hatzakis, John McLauchlan, Aris Katzourakis, Gkikas Magiorkinis

Proc Natl Acad Sci U S A. 2018 Oct 9; 115(41): 10434–10439. Published online 2018 Sep 24. doi: 10.1073/pnas.1811940115

PMCID:: PMC6187174

Abstract Article PDF–1.0M

Select item 51673922.

A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men

Ignacio Novo-Veleiro, Clara Cieza-Borrella, Isabel Pastor, Antonio-Javier Chamorro, Francisco-Javier Laso, Rogelio González-Sarmiento, Miguel Marcos

PLoS One. 2016; 11(12): e0168685. Published online 2016 Dec 19. doi: 10.1371/journal.pone.0168685

PMCID:: PMC5167392

Abstract Article PDF–887K

Select item 71625013.

Reciprocal expression of Annexin A6 and RasGRF2 discriminates rapidly growing from invasive triple negative breast cancer subsets

Olga Y. Korolkova, Sarrah E. Widatalla, Diva S. Whalen, Gladys N. Nangami, Adeniyi Abimbola, Stephen D. Williams, Heather K. Beasley, Emily Reisenbichler, Mary Kay Washington, Josiah Ochieng, Ingrid A. Mayer, Brian D. Lehmann, Amos M. Sakwe

PLoS One. 2020; 15(4): e0231711. Published online 2020 Apr 16. doi: 10.1371/journal.pone.0231711

PMCID:: PMC7162501

Abstract Article PDF–4.2M

Select item 64225034.

RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-κB pathway

Peifen Lu, Junjun Chen, Lihong Yan, Lijun Yang, Litao Zhang, Jie Dai, Zixuan Hao, Tao Bai, Yanfeng Xi, Yahui Li, Zhiming Kang, Jun Xv, Gongqin Sun, Tao Yang

Cancer Biol Ther. 2019; 20(4): 435–443. Published online 2018 Oct 25. doi: 10.1080/15384047.2018.1529117

PMCID:: PMC6422503

Abstract Article PDF–2.1M

Select item 35290665.

RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release

David Stacey, Ainhoa Bilbao, Matthieu Maroteaux, Tianye Jia, Alanna C. Easton, Sophie Longueville, Charlotte Nymberg, Tobias Banaschewski, Gareth J. Barker, Christian Büchel, Fabiana Carvalho, Patricia J. Conrod, Sylvane Desrivières, Mira Fauth-Bühler, Alberto Fernandez-Medarde, Herta Flor, Jürgen Gallinat, Hugh Garavan, Arun L. W. Bokde, Andreas Heinz, Bernd Ittermann, Mark Lathrop, Claire Lawrence, Eva Loth, Anbarasu Lourdusamy, Karl F. Mann, Jean-Luc Martinot, Frauke Nees, Miklós Palkovits, Tomas Paus, Zdenka Pausova, Marcella Rietschel, Barbara Ruggeri, Eugenio Santos, Michael N. Smolka, Oliver Staehlin, Marjo-Riitta Jarvelin, Paul Elliott, Wolfgang H. Sommer, Manuel Mameli, Christian P. Müller, Rainer Spanagel, Jean-Antoine Girault, Gunter Schumann, the IMAGEN Consortium

Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51): 21128–21133. Published online 2012 Dec 5. doi: 10.1073/pnas.1211844110

PMCID:: PMC3529066

Abstract Article PDF–1007K

Select item 2318646.

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras.

N P Fam, W T Fan, Z Wang, L J Zhang, H Chen, M F Moran

Mol Cell Biol. 1997 Mar; 17(3): 1396–1406. doi: 10.1128/mcb.17.3.1396

PMCID:: PMC231864

Summary PDF–1.8M

Select item 868277.

Ras Binding Triggers Ubiquitination of the Ras Exchange Factor Ras-GRF2

Carmen L. de Hoog, Jackie A. Koehler, Marni D. Goldstein, Paul Taylor, Daniel Figeys, Michael F. Moran

Mol Cell Biol. 2001 Mar; 21(6): 2107–2117. doi: 10.1128/MCB.21.6.2107-2117.2001

PMCID:: PMC86827

Abstract Article PDF–4.3M

Select item 21691778.

RasGRF2, a Guanosine Nucleotide Exchange Factor for Ras GTPases, Participates in T-Cell Signaling Responses

Sergio Ruiz, Eugenio Santos, Xosé R. Bustelo

Mol Cell Biol. 2007 Dec; 27(23): 8127–8142. Published online 2007 Oct 8. doi: 10.1128/MCB.00912-07

PMCID:: PMC2169177

Abstract Article PDF–1006K

Select item 27621409.

Structural and Spatial Determinants Regulating TC21 Activation by RasGRF Family Nucleotide Exchange Factors

Fernando Calvo, Piero Crespo

Mol Biol Cell. 2009 Oct 15; 20(20): 4289–4302. doi: 10.1091/mbc.E09-03-0212

PMCID:: PMC2762140

Abstract Article PDF–3.8M

Select item 34418210.

Activation of H-Ras in the Endoplasmic Reticulum by the RasGRF Family Guanine Nucleotide Exchange Factors

Imanol Arozarena, David Matallanas, María T. Berciano, Victoria Sanz-Moreno, Fernando Calvo, María T. Muñoz, Gustavo Egea, Miguel Lafarga, Piero Crespo

Mol Cell Biol. 2004 Feb; 24(4): 1516–1530. doi: 10.1128/MCB.24.4.1516-1530.2004

PMCID:: PMC344182

Abstract Article PDF–1.4M

Select item 522270311.

RasGRF couples Nox4-dependent endoplasmic reticulum signaling to Ras

Ru Feng Wu, Chengxu Liao, Hadi Hatoum, Guosheng Fu, Christhiaan D. Ochoa, Lance S. Terada

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Jan; 37(1): 98–107. Published online 2016 Nov 17. doi: 10.1161/ATVBAHA.116.307922

PMCID:: PMC5222703

Abstract Article PDF–1.5M

Select item 403636812.

βArrestin1 Regulates the Guanine Nucleotide Exchange Factor RasGRF2 Expression and the Small GTPase Rac-mediated Formation of Membrane Protrusion and Cell Motility

Xiaojie Ma, Laura Espana-Serrano, Wan-ju Kim, Hamsa Thayele Purayil, Zhongzhen Nie, Yehia Daaka

J Biol Chem. 2014 May 9; 289(19): 13638–13650. Published online 2014 Apr 1. doi: 10.1074/jbc.M113.511360

PMCID:: PMC4036368

Abstract Article PDF–4.2M

Select item 278841713.

The Use of Knockout Mice Reveals a Synergistic Role of the Vav1 and Rasgrf2 Gene Deficiencies in Lymphomagenesis and Metastasis

Sergio Ruiz, Eugenio Santos, Xosé R. Bustelo

PLoS One. 2009; 4(12): e8229. Published online 2009 Dec 14. doi: 10.1371/journal.pone.0008229

PMCID:: PMC2788417

Abstract Article PDF–890K

Select item 435051614.

Common variants at 1p36 are associated with superior frontal gyrus volume

R Hashimoto, M Ikeda, F Yamashita, K Ohi, H Yamamori, Y Yasuda, M Fujimoto, M Fukunaga, K Nemoto, T Takahashi, M Tochigi, T Onitsuka, H Yamasue, K Matsuo, T Iidaka, N Iwata, M Suzuki, M Takeda, K Kasai, N Ozaki

Transl Psychiatry. 2014 Oct; 4(10): e472. Published online 2014 Oct 21. doi: 10.1038/tp.2014.110

PMCID:: PMC4350516

Abstract Article PDF–677K

Select item 361712715.

Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts

Min Shi, Jeffrey C Murray, Mary L Marazita, Ronald G Munger, Ingo Ruczinski, Jacqueline B Hetmanski, Tao Wu, Tanda Murray, Richard J Redett, Allen J Wilcox, Rolv T Lie, Ethylin Wang Jabs, Yah Huei Wu-Chou, Philip K Chen, Hong Wang, Xiaoqian Ye, Vincent Yeow, Samuel S Chong, Bing Shi, Kaare Christensen, Alan F Scott, Poorav Patel, Felicia Cheah, Terri H Beaty

Am J Med Genet A. Author manuscript; available in PMC 2013 Apr 4.

Published in final edited form as: Am J Med Genet A. 2012 Apr; 0(4): 784–794. Published online 2012 Mar 14. doi: 10.1002/ajmg.a.35257

PMCID:: PMC3617127

Abstract Article PDF–3.2M

Select item 8425916.

Ras-Specific Exchange Factor GRF: Oligomerization through Its Dbl Homology Domain and Calcium-Dependent Activation of Raf

Pieter H. Anborgh, Xiaolan Qian, Alex G. Papageorge, William C. Vass, Jeffrey E. DeClue, Douglas R. Lowy

Mol Cell Biol. 1999 Jul; 19(7): 4611–4622. doi: 10.1128/mcb.19.7.4611

PMCID:: PMC84259

Abstract Article PDF–1.2M

Select item 675758317.

Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis

Anthony W. Harrington, Ju Young Kim, Sung Ok Yoon

J Neurosci. 2002 Jan 1; 22(1): 156–166. doi: 10.1523/JNEUROSCI.22-01-00156.2002

PMCID:: PMC6757583

Abstract Article PDF–582K

Select item 377587418.

Genetic variants associated with disordered eating

Tracey D Wade, Scott Gordon, Sarah Medland, Cynthia M. Bulik, Andrew C Heath, Grant W Montgomery, Nicholas G Martin

Int J Eat Disord. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Int J Eat Disord. 2013 Sep; 46(6): 594–608. Published online 2013 Apr 9. doi: 10.1002/eat.22133

PMCID:: PMC3775874

Abstract Article PDF–2.1M

Select item 992246819.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 361021420.

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

Gaëlle Blandin, Sylvie Marchand, Karine Charton, Nathalie Danièle, Evelyne Gicquel, Jean-Baptiste Boucheteil, Azéddine Bentaib, Laetitia Barrault, Daniel Stockholm, Marc Bartoli, Isabelle Richard

Skelet Muscle. 2013; 3: 3. Published online 2013 Feb 15. doi: 10.1186/2044-5040-3-3

PMCID:: PMC3610214

Abstract Article PDF–1.7M

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