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Items: 1 to 20 of 179

1.
The RanBP2/RanGAP1*SUMO1/Ubc9 complex: A multisubunit E3 ligase at the intersection of sumoylation and the RanGTPase cycle
Annette Flotho, Andreas Werner
Nucleus. 2012 Sep 1; 3(5): 429–432. doi: 10.4161/nucl.21980
PMCID:
PMC3474663
AbstractArticlePDF–327K
2.
Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores
Emanuele Roscioli, Laura Di Francesco, Alessio Bolognesi, Maria Giubettini, Serena Orlando, Amnon Harel, Maria Eugenia Schininà, Patrizia Lavia
J Cell Biol. 2012 Feb 20; 196(4): 435–450. doi: 10.1083/jcb.201109104
PMCID:
PMC3283988
AbstractArticlePDF–3.4M
3.
SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS
Xiaohu Lin, Qianqian Pang, Jie Hu, Jiaqi Sun, Siya Dai, Yijia Yu, Jinghong Xu
J Cell Mol Med. 2023 Apr; 27(8): 1045–1055. Published online 2023 Mar 14. doi: 10.1111/jcmm.17216
PMCID:
PMC10098277
AbstractArticlePDF–2.1M
4.
CircRNA_0079586 and circRNA_RanGAP1 are involved in the pathogenesis of intracranial aneurysms rupture by regulating the expression of MPO
Zhuang Zhang, Rubo Sui, Lili Ge, Dongjian Xia
Sci Rep. 2021; 11: 19800. Published online 2021 Oct 5. doi: 10.1038/s41598-021-99062-w
PMCID:
PMC8492745
AbstractArticlePDF–1.7M
5.
Alternative Allosteric Mechanisms Can Regulate the Substrate and E2 in SUMO Conjugation
Ezgi Karaca, Melda Tozluoğlu, Ruth Nussinov, Türkan Haliloğlu
J Mol Biol. Author manuscript; available in PMC 2020 Aug 3.
Published in final edited form as: J Mol Biol. 2011 Mar 4; 406(4): 620–630. Published online 2011 Jan 7. doi: 10.1016/j.jmb.2010.12.044
PMCID:
PMC7398049
AbstractArticlePDF–1.9M
6.
Polyglutamine-expanded huntingtin exacerbates age-related disruption of nuclear integrity and nucleocytoplasmic transport
Fatima Gasset-Rosa, Carlos Chillon-Marinas, Alexander Goginashvili, Ranjit Singh Atwal, Jonathan W. Artates, Ricardos Tabet, Vanessa C. Wheeler, Anne G. Bang, Don W. Cleveland, Clotilde Lagier-Tourenne
Neuron. Author manuscript; available in PMC 2018 Apr 5.
Published in final edited form as: Neuron. 2017 Apr 5; 94(1): 48–57.e4. doi: 10.1016/j.neuron.2017.03.027
PMCID:
PMC5479704
AbstractArticlePDF–2.6M
7.
Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation
Jingjing Wu, Hu Lei, Jinfu Zhang, Xiangyun Chen, Caixia Tang, Weiwei Wang, Hanzhang Xu, Weilie Xiao, Wenli Gu, Yingli Wu
Oncotarget. 2016 Sep 13; 7(37): 58995–59005. Published online 2016 Jul 16. doi: 10.18632/oncotarget.10636
PMCID:
PMC5312290
AbstractArticlePDF–2.3M
8.
MicroRNA-1301-Mediated RanGAP1 Downregulation Induces BCR-ABL Nuclear Entrapment to Enhance Imatinib Efficacy in Chronic Myeloid Leukemia Cells
Tsung-Yao Lin, Ku-Chung Chen, Hsing-Jin Eugene Liu, Ann-Jeng Liu, Kun-Li Wang, Chwen-Ming Shih
PLoS One. 2016; 11(5): e0156260. Published online 2016 May 26. doi: 10.1371/journal.pone.0156260
Correction in:
PLoS One. 2017; 12(3): e0173828.
PMCID:
PMC4881950
AbstractArticlePDF–3.2M
9.
The Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells
Keith Cha, Progga Sen, Sarita Raghunayakula, Xiang-Dong Zhang
PLoS One. 2015; 10(10): e0141309. Published online 2015 Oct 27. doi: 10.1371/journal.pone.0141309
PMCID:
PMC4624696
AbstractArticlePDF–4.3M
10.
The Ran GTPase-Activating Protein (RanGAP1) Is Critically Involved in Smooth Muscle Cell Differentiation, Proliferation and Migration following Vascular Injury: Implications for Neointima Formation and Restenosis
Marc Vorpahl, Sabine Schönhofer-Merl, Cornelia Michaelis, Annette Flotho, Frauke Melchior, Rainer Wessely
PLoS One. 2014; 9(7): e101519. Published online 2014 Jul 2. doi: 10.1371/journal.pone.0101519
PMCID:
PMC4079658
AbstractArticlePDF–4.8M
11.
Listeria monocytogenes impairs SUMOylation for efficient infection
David Ribet, Mélanie Hamon, Edith Gouin, Marie-Anne Nahori, Francis Impens, Hélène Neyret-Kahn, Kris Gevaert, Joël Vandekerckhove, Anne Dejean, Pascale Cossart
Nature. Author manuscript; available in PMC 2013 Apr 16.
Published in final edited form as: Nature. 2010 Apr 22; 464(7292): 1192–1195. doi: 10.1038/nature08963
PMCID:
PMC3627292
AbstractArticlePDF–1.4M
12.
Protection from Isopeptidase-Mediated Deconjugation Regulates Paralog-Selective Sumoylation of RanGAP1
Shanshan Zhu, Jacqueline Goeres, Katherine M. Sixt, Miklós Békés, Xiang-Dong Zhang, Guy S. Salvesen, Michael J. Matunis
Mol Cell. Author manuscript; available in PMC 2010 Mar 13.
Published in final edited form as: Mol Cell. 2009 Mar 13; 33(5): 570–580. doi: 10.1016/j.molcel.2009.02.008
PMCID:
PMC2668917
AbstractArticlePDF–2.1M
13.
SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles
Jomon Joseph, Shyh-Han Tan, Tatiana S. Karpova, James G. McNally, Mary Dasso
J Cell Biol. 2002 Feb 18; 156(4): 595–602. doi: 10.1083/jcb.200110109
PMCID:
PMC2174074
AbstractArticlePDF–545K
14.
Molecular Characterization of the SUMO-1 Modification of RanGAP1 and Its Role in Nuclear Envelope Association
Rohit Mahajan, Larry Gerace, Frauke Melchior
J Cell Biol. 1998 Jan 26; 140(2): 259–270. doi: 10.1083/jcb.140.2.259
PMCID:
PMC2132567
AbstractArticlePDF–468K
15.
Conserved charged residues in the leucine-rich repeat domain of the Ran GTPase activating protein are required for Ran binding and GTPase activation.
J Haberland, V Gerke
Biochem J. 1999 Nov 1; 343(Pt 3): 653–662.
PMCID:
PMC1220598
SummaryPDF–294K
16.
RanGAP1 induces GTPase activity of nuclear Ras-related Ran.
F R Bischoff, C Klebe, J Kretschmer, A Wittinghofer, H Ponstingl
Proc Natl Acad Sci U S A. 1994 Mar 29; 91(7): 2587–2591. doi: 10.1073/pnas.91.7.2587
PMCID:
PMC43414
SummaryPage BrowsePDF–1.2M
17.
Pregnane X Receptor Is SUMOylated to Repress the Inflammatory Response
Gang Hu, Chenshu Xu, Jeff L. Staudinger
J Pharmacol Exp Ther. 2010 Nov; 335(2): 342–350. doi: 10.1124/jpet.110.171744
PMCID:
PMC2967404
AbstractArticlePDF–1.3M
18.
Mel-18 interacts with RanGAP1 and inhibits its sumoylation
Jie Zhang, Kevin D. Sarge
Biochem Biophys Res Commun. Author manuscript; available in PMC 2009 Oct 17.
Published in final edited form as: Biochem Biophys Res Commun. 2008 Oct 17; 375(2): 252–255. Published online 2008 Aug 14. doi: 10.1016/j.bbrc.2008.08.012
PMCID:
PMC2562451
AbstractArticlePDF–697K
19.
The Nup358-RanGAP Complex Is Required for Efficient Importin α/β-dependent Nuclear Import
Saskia Hutten, Annette Flotho, Frauke Melchior, Ralph H. Kehlenbach
Mol Biol Cell. 2008 May; 19(5): 2300–2310. doi: 10.1091/mbc.E07-12-1279
PMCID:
PMC2366868
AbstractArticlePDF–1.5M
20.
SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex
Michael J. Matunis, Jian Wu, Günter Blobel
J Cell Biol. 1998 Feb 9; 140(3): 499–509. doi: 10.1083/jcb.140.3.499
PMCID:
PMC2140169
AbstractArticlePDF–495K

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