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Items: 1 to 20 of 110

1.
Liver ChREBP deficiency inhibits fructose-induced insulin resistance in pregnant mice and female offspring
Jiaqi Li, Shuang Zhang, Yuyao Sun, Jian Li, Zian Feng, Huaxin Li, Mengxue Zhang, Tengteng Yan, Jihong Han, Yajun Duan
EMBO Rep. 2024 Apr; 25(4): 2097–2117. Published online 2024 Mar 26. doi: 10.1038/s44319-024-00121-w
PMCID:
PMC11014959
AbstractArticlePDF–6.0M
2.
Hepatic ChREBP orchestrates intrahepatic carbohydrate metabolism to limit hepatic glucose 6-phosphate and glycogen accumulation in a mouse model for acute Glycogen Storage Disease type Ib
K.A. Krishnamurthy, M.G.S. Rutten, J.A. Hoogerland, T.H. van Dijk, T. Bos, M. Koehorst, M.P. de Vries, N.J. Kloosterhuis, H. Havinga, B.V. Schomakers, M. van Weeghel, J.C. Wolters, B.M. Bakker, M.H. Oosterveer
Mol Metab. 2024 Jan; 79: 101838. Published online 2023 Nov 22. doi: 10.1016/j.molmet.2023.101838
PMCID:
PMC10716006
AbstractArticlePDF–929K
3.
ChREBPβ is dispensable for the control of glucose homeostasis and energy balance
Emeline Recazens, Geneviève Tavernier, Jérémy Dufau, Camille Bergoglio, Fadila Benhamed, Stéphanie Cassant-Sourdy, Marie-Adeline Marques, Sylvie Caspar-Bauguil, Alice Brion, Laurent Monbrun, Renaud Dentin, Clara Ferrier, Mélanie Leroux, Pierre-Damien Denechaud, Cedric Moro, Jean-Paul Concordet, Catherine Postic, Etienne Mouisel, Dominique Langin
JCI Insight. 2022 Feb 22; 7(4): e153431. Published online 2022 Feb 22. doi: 10.1172/jci.insight.153431
PMCID:
PMC8876429
AbstractArticlePDF–4.1M
4.
Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice
Vincent Nuernberger, Sharif Mortoga, Christoph Metzendorf, Christian Burkert, Katrina Ehricke, Elisa Knuth, Jenny Zimmer, Stephan Singer, Neetika Nath, Majedul Karim, Mohd Yasser, Diego F. Calvisi, Frank Dombrowski, Silvia Ribback
Cells. 2021 Oct; 10(10): 2787. Published online 2021 Oct 18. doi: 10.3390/cells10102787
PMCID:
PMC8534692
AbstractArticlePDF–6.0M
5.
Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a
Yu Lei, Joanne A. Hoogerland, Vincent W. Bloks, Trijnie Bos, Aycha Bleeker, Henk Wolters, Justina C. Wolters, Brenda S. Hijmans, Theo H. van Dijk, Rachel Thomas, Michel van Weeghel, Gilles Mithieux, Riekelt H. Houtkooper, Alain de Bruin, Fabienne Rajas, Folkert Kuipers, Maaike H. Oosterveer
Hepatology. 2020 Nov; 72(5): 1638–1653. Published online 2020 Oct 30. doi: 10.1002/hep.31198
PMCID:
PMC7702155
AbstractArticlePDF–887K
6.
ChREBP deficiency leads to diarrhea-predominant irritable bowel syndrome
Ah-Reum Oh, Seonyong Sohn, Junghoon Lee, Jong-Min Park, Ki Taek Nam, Ki-Baik Hahm, Young-Bum Kim, Ho-Jae Lee, Ji-Young Cha
Metabolism. Author manuscript; available in PMC 2020 Aug 4.
Published in final edited form as: Metabolism. 2018 Aug; 85: 286–297. Published online 2018 Apr 15. doi: 10.1016/j.metabol.2018.04.006
PMCID:
PMC7400734
AbstractArticlePDF–1.0M
7.
ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different Manners
Katsumi Iizuka, Ken Takao, Takehiro Kato, Yukio Horikawa, Jun Takeda
Nutrients. 2018 Nov; 10(11): 1699. Published online 2018 Nov 7. doi: 10.3390/nu10111699
PMCID:
PMC6266805
AbstractArticlePDF–1.1M
8.
Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma
Silvia Ribback, Li Che, Maria G. Pilo, Antonio Cigliano, Gavinella Latte, Giovanni M. Pes, Alberto Porcu, Rosa M. Pascale, Lei Li, Yu Qiao, Frank Dombrowski, Xin Chen, Diego F. Calvisi
Cell Cycle. 2018; 17(12): 1496–1512. Published online 2018 Jul 18. doi: 10.1080/15384101.2018.1489182
PMCID:
PMC6132959
AbstractArticlePDF–2.8M
9.
Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport
Archana Vijayakumar, Pratik Aryal, Jennifer Wen, Ismail Syed, Reema P. Vazirani, Pedro M. Moraes-Vieira, Joao Paulo Camporez, Molly R. Gallop, Rachel J. Perry, Odile D. Peroni, Gerald I. Shulman, Alan Saghatelian, Timothy E. McGraw, Barbara B. Kahn
Cell Rep. Author manuscript; available in PMC 2018 Jan 17.
Published in final edited form as: Cell Rep. 2017 Oct 24; 21(4): 1021–1035. doi: 10.1016/j.celrep.2017.09.091
PMCID:
PMC5771491
AbstractArticlePDF–2.3M
10.
Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice
Tara Jois, Weiyi Chen, Victor Howard, Rebecca Harvey, Kristina Youngs, Claudia Thalmann, Pradip Saha, Lawrence Chan, Michael A. Cowley, Mark W. Sleeman
Mol Metab. 2017 Nov; 6(11): 1381–1394. Published online 2017 Jul 18. doi: 10.1016/j.molmet.2017.07.006
PMCID:
PMC5681238
AbstractArticlePDF–3.5M
11.
Validation, Identification, and Biological Consequences of the Site-specific O-GlcNAcylation Dynamics of Carbohydrate-responsive Element-binding Protein (ChREBP)
An-Qi Yang, Daoyuan Li, Lianli Chi, Xin-Shan Ye
Mol Cell Proteomics. 2017 Jul; 16(7): 1233–1243. Published online 2017 Apr 27. doi: 10.1074/mcp.M116.061416
PMCID:
PMC5500757
AbstractArticlePDF–1.5M
12.
Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity
Deqiang Zhang, Xin Tong, Kyle VanDommelen, Neil Gupta, Kenneth Stamper, Graham F. Brady, Zhuoxian Meng, Jiandie Lin, Liangyou Rui, M. Bishr Omary, Lei Yin
J Clin Invest. 2017 Jun 30; 127(7): 2855–2867. Published online 2017 Jun 19. doi: 10.1172/JCI89934
PMCID:
PMC5490767
AbstractArticlePDF–3.4M
13.
ChREBP refines the hepatic response to fructose to protect the liver from injury
Angela M. Hall, Brian N. Finck
J Clin Invest. 2017 Jun 30; 127(7): 2533–2535. Published online 2017 Jun 19. doi: 10.1172/JCI95008
PMCID:
PMC5490753
AbstractArticlePDF–144K
14.
Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice
Tara Jois, Victor Howard, Kristina Youngs, Michael A. Cowley, Mark W. Sleeman
PLoS One. 2016; 11(12): e0168797. Published online 2016 Dec 19. doi: 10.1371/journal.pone.0168797
PMCID:
PMC5167554
AbstractArticlePDF–4.7M
15.
Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity
N. Poungvarin, J. K. Lee, V. K. Yechoor, M. V. Li, T. Assavapokee, P. Suksaranjit, J. J. Thepsongwajja, P. K. Saha, K. Oka, L. Chan
Diabetologia. Author manuscript; available in PMC 2014 May 5.
Published in final edited form as: Diabetologia. 2012 Jun; 55(6): 1783–1796. Published online 2012 Mar 3. doi: 10.1007/s00125-012-2506-4
PMCID:
PMC4010252
AbstractArticlePDF–2.4M
16.
ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation
Mallikarjuna R. Metukuri, Pili Zhang, Mahesh K. Basantani, Connie Chin, Rachel E. Stamateris, Laura C. Alonso, Karen K. Takane, Roberto Gramignoli, Stephen C. Strom, Robert M. O’Doherty, Andrew F. Stewart, Rupangi C. Vasavada, Adolfo Garcia-Ocaña, Donald K. Scott
Diabetes. 2012 Aug; 61(8): 2004–2015. Published online 2012 Jul 17. doi: 10.2337/db11-0802
PMCID:
PMC3402328
AbstractArticlePDF–2.0M
17.
Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)
Ming V. Li, Weiqin Chen, Romain N Harmancey, Alli M. Nuotio-Antar, Minako Imamura, Pradip Saha, Heinrich Taegtmeyer, Lawrence Chan
Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 May 7.
Published in final edited form as: Biochem Biophys Res Commun. 2010 May 7; 395(3): 395–400. Published online 2010 Apr 9. doi: 10.1016/j.bbrc.2010.04.028
PMCID:
PMC2874883
AbstractArticlePDF–277K
18.
Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation
Renaud Dentin, Fadila Benhamed, Jean-Paul Pégorier, Fabienne Foufelle, Benoit Viollet, Sophie Vaulont, Jean Girard, Catherine Postic
J Clin Invest. 2005 Oct 1; 115(10): 2843–2854. Published online 2005 Sep 22. doi: 10.1172/JCI25256
PMCID:
PMC1224299
AbstractArticlePDF–1.9M
19.
Suppression of hepatic ChREBP⍺-CYP2C50 axis-driven fatty acid oxidation sensitizes mice to diet-induced MASLD/MASH
Deqiang Zhang, Yuee Zhao, Gary Zhang, Daniel Lank, Sarah Cooke, Sujuan Wang, Alli Nuotio-Antar, Xin Tong, Lei Yin
Mol Metab. 2024 Jul; 85: 101957. Published online 2024 May 11. doi: 10.1016/j.molmet.2024.101957
PMCID:
PMC11145360
AbstractArticlePDF–4.8M
20.
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
Anna Worthmann, Julius Ridder, Sharlaine Y. L. Piel, Ioannis Evangelakos, Melina Musfeldt, Hannah Voß, Marie O’Farrell, Alexander W. Fischer, Sangeeta Adak, Monica Sundd, Hasibullah Siffeti, Friederike Haumann, Katja Kloth, Tatjana Bierhals, Markus Heine, Paul Pertzborn, Mira Pauly, Julia-Josefine Scholz, Suman Kundu, Marceline M. Fuh, Axel Neu, Klaus Tödter, Maja Hempel, Uwe Knippschild, Clay F. Semenkovich, Hartmut Schlüter, Joerg Heeren, Ludger Scheja, Christian Kubisch, Christian Schlein
Nat Commun. 2024; 15: 45. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44364-y
PMCID:
PMC10762034
AbstractArticlePDF–1.0M

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