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Select item 109952081.

Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis

Chuan Yang, Xueping Wang, Kenneth K. W. To, Caimei Cui, Min Luo, Shaocong Wu, Lamei Huang, Kai Fu, Can Pan, Zeyu Liu, Teng Fan, Caibo Yang, Fang Wang, Liwu Fu

Signal Transduct Target Ther. 2024; 9: 84. Published online 2024 Apr 5. doi: 10.1038/s41392-024-01789-1

PMCID:: PMC10995208

Abstract Article PDF–7.0M

Select item 106675272.

PTPRC functions as a prognosis biomarker in the tumor microenvironment of cutaneous melanoma

Xuemei Li, Zhanghui Yue, Dan Wang, Lu Zhou

Sci Rep. 2023; 13: 20617. Published online 2023 Nov 23. doi: 10.1038/s41598-023-46794-6

PMCID:: PMC10667527

Abstract Article PDF–13M

Select item 103782413.

CD45RA and CD45RO Are Regulated in a Cell-Type Specific Manner in Inflammation and Sepsis

Muhammad G. T. Ahmed, Andreas Limmer, Matthias Hartmann

Cells. 2023 Jul; 12(14): 1873. Published online 2023 Jul 17. doi: 10.3390/cells12141873

PMCID:: PMC10378241

Abstract Article PDF–2.9M

Select item 101330274.

CD45 is sufficient to initiate EndMT in human endothelial cells

Sana Nasim, Jill Wylie-Sears, Xinlei Gao, Qianman Peng, Bo Zhu, Kaifu Chen, Hong Chen, Joyce Bischoff

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2023 May; 43(5): e124–e131. Published online 2023 Mar 16. doi: 10.1161/ATVBAHA.122.318172

PMCID:: PMC10133027

Abstract Article PDF–1.4M

Select item 99783155.

Upregulation of PTPRC and Interferon Response Pathways in HIV-1 Seroconverters Prior to Infection

Yunqi Li, Francois Lefebvre, Edith Nakku-Joloba, Allan Ronald, Glenda Gray, Guy de Bruyn, James Kiarie, Connie Celum, Mark J Cameron, Jairam R Lingappa, Romel D Mackelprang

J Infect Dis. 2023 Mar 1; 227(5): 714–719. Published online 2023 Jan 13. doi: 10.1093/infdis/jiac498

PMCID:: PMC9978315

Abstract Article PDF–575K

Select item 84190506.

Aberrant activation of the CD45-Wnt signaling axis promotes stemness and therapy resistance in colorectal cancer cells

So-Yeon Park, Ji-Young Kim, Gyu-Beom Jang, Jang-Hyun Choi, Jee-Heun Kim, Choong-Jae Lee, Sunjae Lee, Jeong-Heum Baek, Kwan-Kyu Park, Jin-Man Kim, Hee Jin Chang, Nam-Chul Cho, Jeong-Seok Nam

Theranostics. 2021; 11(18): 8755–8770. Published online 2021 Aug 11. doi: 10.7150/thno.63446

PMCID:: PMC8419050

Abstract Article PDF–3.9M

Select item 83808967.

Protein tyrosine phosphatase receptor type C (PTPRC or CD45)

Maryam Ahmed Al Barashdi, Ahlam Ali, Mary Frances McMullin, Ken Mills

J Clin Pathol. 2021 Sep; 74(9): 548–552. Published online 2021 May 26. doi: 10.1136/jclinpath-2020-206927

PMCID:: PMC8380896

Abstract Article PDF–898K

Select item 76865028.

High CD45 expression of CD8+ and CD4+ T cells correlates with the size of HIV-1 reservoir in blood

Stefan Petkov, Yonas Bekele, Tadepally Lakshmikanth, Bo Hejdeman, Maurizio Zazzi, Petter Brodin, Francesca Chiodi

Sci Rep. 2020; 10: 20425. Published online 2020 Nov 24. doi: 10.1038/s41598-020-77433-z

PMCID:: PMC7686502

Abstract Article PDF–2.8M

Select item 75862709.

A Novel Type of Stem Cells Double-Positive for SSEA-3 and CD45 in Human Peripheral Blood

Tetsuya Sato, Shohei Wakao, Yoshihiro Kushida, Kazuki Tatsumi, Masaaki Kitada, Takatsugu Abe, Kuniyasu Niizuma, Teiji Tominaga, Shigeki Kushimoto, Mari Dezawa

Cell Transplant. 2020 Jan-Dec; 29: 0963689720923574. Published online 2020 Jun 11. doi: 10.1177/0963689720923574

PMCID:: PMC7586270

Abstract Article PDF–2.9M

Select item 734244210.

CD45在初诊多发性骨髓瘤患者的表达及预后判断中的意义

时杰, 朱尊民, 孙恺, 雷平冲, 刘忠文, 郭建民, 杨靖, 藏玉柱, 张茵

Zhonghua Xue Ye Xue Za Zhi. 2019 Sep; 40(9): 744–749. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2019.09.006

PMCID:: PMC7342442

Abstract Article PDF–920K

Select item 715580811.

CD45RB Status of CD8⁺ T Cell Memory Defines T Cell Receptor Affinity and Persistence

Scott M. Krummey, Anna B. Morris, Jesica R. Jacobs, Donald J. McGuire, Satomi Ando, Katherine P. Tong, Weiwen Zhang, Jennifer Robertson, Sara A Guasch, Koichi Araki, Christian P. Larsen, Brian D. Evavold, Haydn T. Kissick, Mandy L. Ford

Cell Rep. Author manuscript; available in PMC 2020 Apr 14.

Published in final edited form as: Cell Rep. 2020 Feb 4; 30(5): 1282–1291.e5. doi: 10.1016/j.celrep.2020.01.016

PMCID:: PMC7155808

Abstract Article PDF–1.9M

Select item 712759812.

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

Jeanette T. Pingel, Matthew L. Thomas

Cell. 1989 Sep 22; 58(6): 1055–1065. Published online 2004 May 7. doi: 10.1016/0092-8674(89)90504-7

PMCID:: PMC7127598

Abstract Article PDF–1.5M

Select item 582189513.

Nanoscale kinetic segregation of TCR and CD45 in engaged microvilli facilitates early T cell activation

Yair Razvag, Yair Neve-Oz, Julia Sajman, Meital Reches, Eilon Sherman

Nat Commun. 2018; 9: 732. Published online 2018 Feb 21. doi: 10.1038/s41467-018-03127-w

PMCID:: PMC5821895

Abstract Article PDF–3.9M

Select item 568419214.

Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA

Yuan Tian, Mariana Babor, Jerome Lane, Veronique Schulten, Veena S. Patil, Grégory Seumois, Sandy L. Rosales, Zheng Fu, Gaelle Picarda, Julie Burel, Jose Zapardiel-Gonzalo, Rashika N. Tennekoon, Aruna D. De Silva, Sunil Premawansa, Gayani Premawansa, Ananda Wijewickrama, Jason A. Greenbaum, Pandurangan Vijayanand, Daniela Weiskopf, Alessandro Sette, Bjoern Peters

Nat Commun. 2017; 8: 1473. Published online 2017 Nov 13. doi: 10.1038/s41467-017-01728-5

PMCID:: PMC5684192

Abstract Article PDF–2.0M

Select item 553627315.

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease

Johannes Landskron, Sigrid M. Kraggerud, Elisabeth Wik, Anne Dørum, Merete Bjørnslett, Espen Melum, Øystein Helland, Line Bjørge, Ragnhild A. Lothe, Helga B. Salvesen, Kjetil Taskén

PLoS One. 2017; 12(7): e0182030. Published online 2017 Jul 31. doi: 10.1371/journal.pone.0182030

PMCID:: PMC5536273

Abstract Article PDF–2.4M

Select item 524466816.

The soluble cytoplasmic tail of CD45 (ct‐CD45) in human plasma contributes to keep T cells in a quiescent state

Alexander Puck, Stefan Hopf, Madhura Modak, Otto Majdic, Petra Cejka, Stephan Blüml, Klaus Schmetterer, Catharina Arnold‐Schrauf, Jens G. Gerwien, Klaus S. Frederiksen, Elisabeth Thell, Judith Leitner, Peter Steinberger, Regina Aigner, Maria Seyerl‐Jiresch, Gerhard J. Zlabinger, Johannes Stöckl

Eur J Immunol. 2017 Jan; 47(1): 193–205. Published online 2016 Oct 31. doi: 10.1002/eji.201646405

PMCID:: PMC5244668

Abstract Article PDF–1.6M

Select item 508092417.

Side scatter versus CD45 flow cytometric plot can distinguish acute leukaemia subtypes

Annapurna Saksena, Parul Gautam, Parth Desai, Naresh Gupta, A. P. Dubey, Tejinder Singh

Indian J Med Res. 2016 May; 143(Suppl 1): S17–S22. doi: 10.4103/0971-5916.191743

PMCID:: PMC5080924

Abstract Article PDF–740K

Select item 483950418.

Initiation of T cell signaling by CD45 segregation at ‘close-contacts’

Veronica T Chang, Ricardo A Fernandes, Kristina A Ganzinger, Steven F Lee, Christian Siebold, James McColl, Peter Jönsson, Matthieu Palayret, Karl Harlos, Charlotte H Coles, E Yvonne Jones, Yuan Lui, Elizabeth Huang, Robert J C Gilbert, David Klenerman, A Radu Aricescu, Simon J Davis

Nat Immunol. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Nat Immunol. 2016 May; 17(5): 574–582. Published online 2016 Mar 21. doi: 10.1038/ni.3392

PMCID:: PMC4839504

Abstract Article PDF–2.8M

Select item 483707919.

The Prognostic Significance of CD45 Expression by Clonal Bone Marrow Plasma Cells in Patients with Newly Diagnosed Multiple Myeloma

Wilson I. Gonsalves, Michael M. Timm, S. Vincent Rajkumar, William G. Morice, Angela Dispenzieri, Francis K. Buadi, Martha Q. Lacy, David Dingli, Nelson Leung, Prashant Kapoor, Robert A Kyle, Morie A. Gertz, Shaji K Kumar

Leuk Res. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Leuk Res. 2016 May; 44: 32–39. Published online 2016 Mar 10. doi: 10.1016/j.leukres.2016.03.003

PMCID:: PMC4837079

Abstract Article PDF–943K

Select item 468188920.

CD45RO⁺ Memory T Lymphocytes — a Candidate Marker for TNM-Immunoscore in Squamous Non–Small Cell Lung Cancer

Erna-Elise Paulsen, Thomas Kilvaer, Mehrdad Rakaee Khanehkenari, Ramona Johansen Maurseth, Samer Al-Saad, Sigurd M. Hald, Khalid Al-Shibli, Sigve Andersen, Elin Richardsen, Lill-Tove Busund, Roy Bremnes, Tom Donnem

Neoplasia. 2015 Nov; 17(11): 839–848. Published online 2015 Dec 8. doi: 10.1016/j.neo.2015.11.004

PMCID:: PMC4681889

Abstract Article PDF–982K

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PMC Links for Gene (Select 5788) (119)
PMC
PREDICTED: Homo sapiens protein tyrosine phosphatase receptor type C (PTPRC), tr...
PREDICTED: Homo sapiens protein tyrosine phosphatase receptor type C (PTPRC), transcript variant X3, mRNA
gi|2462511982|ref|XM_054337947.1|

Nucleotide
PREDICTED: Homo sapiens protein tyrosine phosphatase receptor type C (PTPRC), tr...
PREDICTED: Homo sapiens protein tyrosine phosphatase receptor type C (PTPRC), transcript variant X1, mRNA
gi|2217269633|ref|XM_047426381.1|

Nucleotide
Homo sapiens protein tyrosine phosphatase receptor type C (PTPRC), transcript va...
Homo sapiens protein tyrosine phosphatase receptor type C (PTPRC), transcript variant 1, mRNA
gi|1519244364|ref|NM_002838.5|

Nucleotide

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