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Select item 86411431.

Structural characterization of the interaction between α_MI-domain of the integrin Mac-1 (α_Mβ₂) and the cytokine pleiotrophin

Wei Feng, Hoa Nguyen, Di Shen, Hanqing Deng, Zhoumai Jiang, Nataly Podolnikova, Tatiana Ugarova, Xu Wang

Biochemistry. Author manuscript; available in PMC 2021 Dec 3.

Published in final edited form as: Biochemistry. 2021 Jan 26; 60(3): 182–193. Published online 2021 Jan 11. doi: 10.1021/acs.biochem.0c00700

PMCID:: PMC8641143

Abstract Article PDF–2.2M

Select item 86310082.

Flexibility and Adaptability in Pleiotrophin’s Interactions with Glycosaminoglycans

Eathen Ryan, Shen Di, Wang Xu

FEBS Lett. Author manuscript; available in PMC 2021 Nov 30.

Published in final edited form as: FEBS Lett. 2021 Apr; 595(7): 925–941. Published online 2021 Feb 12. doi: 10.1002/1873-3468.14052

PMCID:: PMC8631008

Abstract Article PDF–2.7M

Select item 79213973.

Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer

Shiqin Liu, Michelle Shen, En-Chi Hsu, Chiyuan Amy Zhang, Fernando Garcia-Marques, Rosalie Nolley, Kashyap Koul, Meghan A. Rice, Merve Aslan, Sharon J. Pitteri, Charlie Massie, Anne George, James D. Brooks, Vincent J. Gnanapragasam, Tanya Stoyanova

Br J Cancer. 2021 Mar 2; 124(5): 896–900. Published online 2020 Dec 8. doi: 10.1038/s41416-020-01200-0

PMCID:: PMC7921397

Abstract Article PDF–528K

Select item 76728824.

Pleiotrophin: Activity and Mechanism

Xu Wang

Adv Clin Chem. Author manuscript; available in PMC 2020 Nov 18.

Published in final edited form as: Adv Clin Chem. 2020; 98: 51–89. Published online 2020 Mar 12. doi: 10.1016/bs.acc.2020.02.003

PMCID:: PMC7672882

Abstract Article PDF–1.2M

Select item 76593675.

Implications of pleiotrophin in human PC3 prostate cancer cell growth in vivo

Sotiria Tsirmoula, Kostas Dimas, Maria Hatziapostolou, Margarita Lamprou, Panagiota Ravazoula, Evangelia Papadimitriou

Cancer Sci. 2012 Oct; 103(10): 1826–1832. Published online 2012 Aug 14. doi: 10.1111/j.1349-7006.2012.02383.x

PMCID:: PMC7659367

Abstract Article PDF–457K

Select item 63782016.

Serum pleiotrophin as a diagnostic and prognostic marker for small cell lung cancer

Chunhua Xu, Yuchao Wang, Qi Yuan, Wei Wang, Chuanzhen Chi, Qian Zhang, Xiuwei Zhang

J Cell Mol Med. 2019 Mar; 23(3): 2077–2082. Published online 2019 Jan 11. doi: 10.1111/jcmm.14116

PMCID:: PMC6378201

Abstract Article PDF–321K

Select item 62353617.

A meta-analysis on the role of pleiotrophin (PTN) as a prognostic factor in cancer

Jiupeng Zhou, Yuanli Yang, Yongfeng Zhang, Heng Liu, Quanli Dou

PLoS One. 2018; 13(11): e0207473. Published online 2018 Nov 14. doi: 10.1371/journal.pone.0207473

PMCID:: PMC6235361

Abstract Article PDF–1.7M

Select item 55871598.

Neural precursor-derived pleiotrophin mediates subventricular zone invasion by glioma

Elizabeth Y. Qin, Dominique D. Cooper, Keene L. Abbott, James Lennon, Surya Nagaraja, Alan Mackay, Chris Jones, Hannes Vogel, Peter K. Jackson, Michelle Monje

Cell. Author manuscript; available in PMC 2018 Aug 24.

Published in final edited form as: Cell. 2017 Aug 24; 170(5): 845–859.e19. Published online 2017 Aug 17. doi: 10.1016/j.cell.2017.07.016

PMCID:: PMC5587159

Abstract Article PDF–3.1M

Select item 50121539.

Early Disruption of Extracellular Pleiotrophin Distribution Alters Cerebellar Neuronal Circuit Development and Function

M. M. Hamza, S. A. Rey, P. Hilber, A. Arabo, T. Collin, D. Vaudry, D. Burel

Mol Neurobiol. 2016; 53(8): 5203–5216. Published online 2015 Sep 24. doi: 10.1007/s12035-015-9450-5

PMCID:: PMC5012153

Abstract Article PDF–1.6M

Select item 476780310.

Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer

Youn Hee Jee, Samira M. Sadowski, Francesco S. Celi, Liqiang Xi, Mark Raffeld, David B. Sacks, Alan T. Remaley, Anton Wellstein, Electron Kebebew, Jeffrey Baron

PLoS One. 2016; 11(2): e0149383. Published online 2016 Feb 25. doi: 10.1371/journal.pone.0149383

PMCID:: PMC4767803

Abstract Article PDF–2.1M

Select item 445634311.

PTN Signaling: Components and Mechanistic Insights in Human Ovarian Cancer

Geetika Sethi, Youngjoo Kwon, Rebecca J Burkhalter, Harsh B. Pathak, Rashna Madan, Sarah McHugh, Safinur Atay, Smruthi Murthy, Ossama W. Tawfik, Andrew K. Godwin

Mol Carcinog. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Mol Carcinog. 2015 Dec; 54(12): 1772–1785. Published online 2014 Nov 21. doi: 10.1002/mc.22249

PMCID:: PMC4456343

Abstract Article PDF–1.6M

Select item 340718712.

Expression Analysis of Macrodactyly Identifies Pleiotrophin Upregulation

Frank H. Lau, Fang Xia, Adam Kaplan, Felecia Cerrato, Arin K. Greene, Amir Taghinia, Chad A. Cowan, Brian I. Labow

PLoS One. 2012; 7(7): e40423. Published online 2012 Jul 27. doi: 10.1371/journal.pone.0040423

PMCID:: PMC3407187

Abstract Article PDF–2.1M

Select item 304565913.

Expression of Pleiotrophin in the Prostate is Androgen Regulated and it Functions as an Autocrine Regulator of Mesenchyme and Cancer Associated Fibroblasts and as a Paracrine Regulator of Epithelia

Brigid Orr, Griet Vanpoucke, O Cathal Grace, Lee Smith, Richard A Anderson, Antony CP Riddick, Omar E Franco, Simon W Hayward, Axel A Thomson

Prostate. 2011 Feb 15; 71(3): 305–317. Published online 2010 Sep 1. doi: 10.1002/pros.21244

PMCID:: PMC3045659

Abstract Article PDF–538K

Select item 283013314.

Pleiotrophin (PTN) is expressed in vascularized human atherosclerotic plaques: IFN-γ/JAK/STAT1 signaling is critical for the expression of PTN in macrophages

Fuqiang Li, Fang Tian, Lai Wang, Ian K. Williamson, Behrooz G. Sharifi, Prediman K. Shah

FASEB J. 2010 Mar; 24(3): 810–822. doi: 10.1096/fj.09-140780

PMCID:: PMC2830133

Abstract Article

Select item 265101315.

Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis

Haiming Chen, Richard A. Campbell, Yunchao Chang, Mingjie Li, Cathy S. Wang, Jennifer Li, Eric Sanchez, Michael Share, Jeffrey Steinberg, Ariana Berenson, Dror Shalitin, Zhaohui Zeng, Dorina Gui, Pablo Perez-Pinera, Ronald J. Berenson, Jonathan Said, Benjamin Bonavida, Thomas F. Deuel, James R. Berenson

Blood. 2009 Feb 26; 113(9): 1992–2002. Prepublished online 2008 Dec 5. doi: 10.1182/blood-2008-02-133751

PMCID:: PMC2651013

Abstract Article

Select item 190416016.

Secretion of pleiotrophin stimulates breast cancer progression through remodeling of the tumor microenvironment

Yunchao Chang, Masahiko Zuka, Pablo Perez-Pinera, Aurora Astudillo, Joanne Mortimer, James R. Berenson, Thomas F. Deuel

Proc Natl Acad Sci U S A. 2007 Jun 26; 104(26): 10888–10893. Published online 2007 Jun 19. doi: 10.1073/pnas.0704366104

PMCID:: PMC1904160

Abstract Article PDF–898K

Select item 185096317.

Dominant Negative Pleiotrophin Induces Tetraploidy and Aneuploidy in U87MG Human Glioblastoma Cells

Yunchao Chang, James R. Berenson, Zhaoyi Wang, Thomas F. Deuel

Biochem Biophys Res Commun. Author manuscript; available in PMC 2007 Dec 15.

Published in final edited form as: Biochem Biophys Res Commun. 2006 Dec 15; 351(2): 336–339. Published online 2006 Oct 5. doi: 10.1016/j.bbrc.2006.09.148

PMCID:: PMC1850963

Abstract Article PDF–92K

Select item 1057897918.

Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs

Elias A. Said, Sumaya Al-Dughaishi, Wadha Al-Hatmi, Iman Al-Reesi, Mohammed S. Al-Balushi, Atika Al-Bimani, Juma Z. Al-Busaidi, Marwa Al-Riyami, Murtadha Al-Khabori, Salam Al-Kindi, Francesco A. Procopio, Shadia Al-Sinawi, Aliyaa Al-Ansari, Crystal Y. Koh, Khalid Al-Naamani, Ali A. Al-Jabri

J Immunol Res. 2023; 2023: 7944102. Published online 2023 Oct 9. doi: 10.1155/2023/7944102

PMCID:: PMC10578979

Abstract Article PDF–9.8M

Select item 999896419.

Pleiotrophin drives a prometastatic immune niche in breast cancer

Debolina Ganguly, Marcel O. Schmidt, Morgan Coleman, Tuong-Vi Cindy Ngo, Noah Sorrelle, Adrian T.A. Dominguez, Gilbert Z. Murimwa, Jason E. Toombs, Cheryl Lewis, Yisheng V. Fang, Fatima Valdes-Mora, David Gallego-Ortega, Anton Wellstein, Rolf A. Brekken

J Exp Med. 2023 May 1; 220(5): e20220610. Published online 2023 Feb 24. doi: 10.1084/jem.20220610

PMCID:: PMC9998964

Abstract Article PDF–8.7M

Select item 704679420.

Association of Midkine and Pleiotrophin Gene Polymorphisms With Systemic Lupus Erythematosus Susceptibility in Chinese Han Population

Peng Wang, Yan-Mei Mao, Chan-Na Zhao, Jie-Bing Wang, Xiao-Mei Li, Dong-Qing Ye, Hai-Feng Pan

Front Immunol. 2020; 11: 110. Published online 2020 Feb 21. doi: 10.3389/fimmu.2020.00110

PMCID:: PMC7046794

Abstract Article PDF–324K

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redox-regulated ATPase YchF [Streptococcus pyogenes]
redox-regulated ATPase YchF [Streptococcus pyogenes]
gi|527103513|ref|WP_020904804.1|

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