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Select item 84852211.

Multi-omics analysis to identify susceptibility genes for colorectal cancer

Yuan Yuan, Jiandong Bao, Zhishan Chen, Anna Díez Villanueva, Wanqing Wen, Fangqin Wang, Dejian Zhao, Xianghui Fu, Qiuyin Cai, Jirong Long, Xiao-ou Shu, Deyou Zheng, Victor Moreno, Wei Zheng, Weiqiang Lin, Xingyi Guo

Hum Mol Genet. 2021 Mar 1; 30(5): 321–330. Published online 2021 Jan 22. doi: 10.1093/hmg/ddab021

PMCID:: PMC8485221

Abstract Article PDF–1.0M

Select item 50986012.

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Richard S Houlston, Jeremy Cheadle, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Sarah L Spain, Peter Broderick, Enric Domingo, Susan Farrington, James GD Prendergast, Alan M Pittman, Evi Theodoratou, Christopher G Smith, Bianca Olver, Axel Walther, Rebecca A Barnetson, Michael Churchman, Emma EM Jaeger, Steven Penegar, Ella Barclay, Lynn Martin, Maggie Gorman, Rachel Mager, Elaine Johnstone, Rachel Midgley, Iina Niittymäki, Sari Tuupanen, James Colley, Shelley Idziaszczyk, The COGENT Consortium, Huw JM Thomas, Anneke M Lucassen, D Gareth R Evans, Eamonn R Maher, The CORGI Consortium, The COIN Collaborative Group, The COINB Collaborative Group, Timothy Maughan, Antigone Dimas, Emmanouil Dermitzakis, Jean-Baptiste Cazier, Lauri A Aaltonen, Paul Pharoah, David J Kerr, Luis G Carvajal-Carmona, Harry Campbell, Malcolm G Dunlop, Ian PM Tomlinson

Nat Genet. Author manuscript; available in PMC 2016 Nov 7.

Published in final edited form as: Nat Genet. 2010 Nov; 42(11): 973–977. Published online 2010 Oct 24. doi: 10.1038/ng.670

PMCID:: PMC5098601

Abstract Article PDF–1.0M

Select item 17853583.

CGG-Repeat Expansion in the DIP2B Gene Is Associated with the Fragile Site FRA12A on Chromosome 12q13.1

Birgitta Winnepenninckx, Kim Debacker, Jacqueline Ramsay, Dominique Smeets, Arie Smits, David R. FitzPatrick, R. Frank Kooy

Am J Hum Genet. 2007 Feb; 80(2): 221–231. Published online 2006 Dec 12. doi: 10.1086/510800

PMCID:: PMC1785358

Abstract Article PDF–1.4M

Select item 41335844.

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

Nicola Whiffin, Fay J. Hosking, Susan M. Farrington, Claire Palles, Sara E. Dobbins, Lina Zgaga, Amy Lloyd, Ben Kinnersley, Maggie Gorman, Albert Tenesa, Peter Broderick, Yufei Wang, Ella Barclay, Caroline Hayward, Lynn Martin, Daniel D. Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M. Lindor, Polly A. Newcomb, Steve Gallinger, David Conti, Fred Schumacher, Graham Casey, Tao Liu, The Swedish Low-Risk Colorectal Cancer Study Group, Harry Campbell, Annika Lindblom, Richard S. Houlston, Ian P. Tomlinson, Malcolm G. Dunlop

Hum Mol Genet. 2014 Sep 1; 23(17): 4729–4737. Published online 2014 Apr 15. doi: 10.1093/hmg/ddu177

PMCID:: PMC4133584

Abstract Article PDF–460K

Select item 38420255.

A Multi-Ethnic Meta-Analysis of Genome-Wide Association Studies in Over 100,000 Subjects Identifies 23 Fibrinogen-Associated Loci but no Strong Evidence of a Causal Association between Circulating Fibrinogen and Cardiovascular Disease

Maria Sabater-Lleal, Jie Huang, Daniel Chasman, Silvia Naitza, Abbas Dehghan, Andrew D Johnson, Alexander Teumer, Alex P Reiner, Lasse Folkersen, Saonli Basu, Alicja R Rudnicka, Stella Trompet, Anders Mälarstig, Jens Baumert, Joshua C. Bis, Xiuqing Guo, Jouke J Hottenga, So-Youn Shin, Lorna M Lopez, Jari Lahti, Toshiko Tanaka, Lisa R Yanek, Tiphaine Oudot-Mellakh, James F Wilson, Pau Navarro, Jennifer E Huffman, Tatijana Zemunik, Susan Redline, Reena Mehra, Drazen Pulanic, Igor Rudan, Alan F Wright, Ivana Kolcic, Ozren Polasek, Sarah H Wild, Harry Campbell, J David Curb, Robert Wallace, Simin Liu, Charles B. Eaton, Diane M. Becker, Lewis C. Becker, Stefania Bandinelli, Katri Räikkönen, Elisabeth Widen, Aarno Palotie, Myriam Fornage, David Green, Myron Gross, Gail Davies, Sarah E Harris, David C Liewald, John M Starr, Frances M.K. Williams, P.J. Grant, Timothy D. Spector, Rona J Strawbridge, Angela Silveira, Bengt Sennblad, Fernando Rivadeneira, Andre G Uitterlinden, Oscar H Franco, Albert Hofman, Jenny van Dongen, G Willemsen, Dorret I Boomsma, Jie Yao, Nancy Swords Jenny, Talin Haritunians, Barbara McKnight, Thomas Lumley, Kent D Taylor, Jerome I Rotter, Bruce M Psaty, Annette Peters, Christian Gieger, Thomas Illig, Anne Grotevendt, Georg Homuth, Henry Völzke, Thomas Kocher, Anuj Goel, Maria Grazia Franzosi, Udo Seedorf, Robert Clarke, Maristella Steri, Kirill V Tarasov, Serena Sanna, David Schlessinger, David J Stott, Naveed Sattar, Brendan M Buckley, Ann Rumley, Gordon D Lowe, Wendy L McArdle, Ming-Huei Chen, Geoffrey H Tofler, Jaejoon Song, Eric Boerwinkle, Aaron R. Folsom, Lynda M. Rose, Anders Franco-Cereceda, Martina Teichert, M Arfan Ikram, Thomas H Mosley, Steve Bevan, Martin Dichgans, Peter M. Rothwell, Cathie L M Sudlow, Jemma C. Hopewell, John C. Chambers, Danish Saleheen, Jaspal S. Kooner, John Danesh, Christopher P Nelson, Jeanette Erdmann, Muredach P. Reilly, Sekar Kathiresan, Heribert Schunkert, Pierre-Emmanuel Morange, Luigi Ferrucci, Johan G Eriksson, David Jacobs, Ian J Deary, Nicole Soranzo, Jacqueline CM Witteman, Eco JC de Geus, Russell P. Tracy, Caroline Hayward, Wolfgang Koenig, Francesco Cucca, J Wouter Jukema, Per Eriksson, Sudha Seshadri, Hugh S. Markus, Hugh Watkins, Nilesh J Samani, VTE consortium, STROKE Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), C4D consortium, CARDIoGRAM consortium, Henri Wallaschofski, Nicholas L. Smith, David Tregouet, Paul M. Ridker, Weihong Tang, David P. Strachan, Anders Hamsten, Christopher J. O’Donnell

Circulation. Author manuscript; available in PMC 2014 Sep 17.

Published in final edited form as: Circulation. 2013 Sep 17; 128(12): 10.1161/CIRCULATIONAHA.113.002251. Published online 2013 Aug 22. doi: 10.1161/CIRCULATIONAHA.113.002251

PMCID:: PMC3842025

Abstract Article PDF–917K

Select item 32504796.

Defining human ERAD networks through an integrative mapping strategy

John C. Christianson, James A. Olzmann, Thomas A. Shaler, Mathew E. Sowa, Eric J. Bennett, Caleb M. Richter, Ryan E. Tyler, Ethan J. Greenblatt, J. Wade Harper, Ron R. Kopito

Nat Cell Biol. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Nat Cell Biol. 2012 Jan; 14(1): 93–105. Published online 2011 Nov 27. doi: 10.1038/ncb2383

PMCID:: PMC3250479

Abstract Article PDF–2.7M

Select item 79484527.

A conserved acetylation switch enables pharmacological control of tubby-like protein stability

Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard

J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839

PMCID:: PMC7948452

Abstract Article PDF–3.6M

Select item 82101848.

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma

Verónica Freire-Benéitez, Nicola Pomella, Thomas O Millner, Anaëlle A Dumas, Maria Victoria Niklison-Chirou, Eleni Maniati, Jun Wang, Vinothini Rajeeve, Pedro Cutillas, Silvia Marino

NAR Cancer. 2021 Mar; 3(1): zcab009. Published online 2021 Mar 22. doi: 10.1093/narcan/zcab009

Correction in:: NAR Cancer. 2021 Jun; 3(2): zcab020.

PMCID:: PMC8210184

Abstract Article PDF–3.4M

Select item 109168669.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 290199810.

Network organization of the human autophagy system

Christian Behrends, Mathew E. Sowa, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Nature. 2010 Jul 1; 466(7302): 68–76. Published online 2010 Jun 20. doi: 10.1038/nature09204

PMCID:: PMC2901998

Abstract Article PDF–1.4M

Select item 997863511.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 885704912.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 638658813.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 51444614.

Large-scale characterization of HeLa cell nuclear phosphoproteins

Sean A. Beausoleil, Mark Jedrychowski, Daniel Schwartz, Joshua E. Elias, Judit Villén, Jiaxu Li, Martin A. Cohn, Lewis C. Cantley, Steven P. Gygi

Proc Natl Acad Sci U S A. 2004 Aug 17; 101(33): 12130–12135. Published online 2004 Aug 9. doi: 10.1073/pnas.0404720101

PMCID:: PMC514446

Abstract Article PDF–475K

Select item 563060015.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 554841316.

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling

Parveen Kumar, Prathyusha Munnangi, KVS Rammohan Chowdary, Varun J. Shah, Swapnil R. Shinde, Nanci R. Kolli, Rachita R. Halehalli, Hampapathalu A. Nagarajaram, Subbareddy Maddika

J Proteome Res. 2017 Aug 4; 16(8): 2789–2801. Published online 2017 Jul 4. doi: 10.1021/acs.jproteome.7b00065

PMCID:: PMC5548413

Abstract Article PDF–5.2M

Select item 633346017.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 549522518.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 917141119.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 268304720.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

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