PMC Links for Gene (Select 56643) - PMC

Dimitri Tchernitchko, Quentin Tavernier, Jérôme Lamoril, Caroline Schmitt, Neila Talbi, Said Lyoumi, Anne-Marie Robreau, Zoubida Karim, Laurent Gouya, Eric Thervet, Alexandre Karras, Hervé Puy, Nicolas Pallet

J Am Soc Nephrol. 2017 Jun; 28(6): 1924–1932. Published online 2016 Dec 28. doi: 10.1681/ASN.2016080918

PMCID:: PMC5461799

Abstract Article

Select item 48905335.

PepT1 Expression Helps Maintain Intestinal Homeostasis by Mediating the Differential Expression of miRNAs along the Crypt-Villus Axis

Yuchen Zhang, Emilie Viennois, Mingzhen Zhang, Bo Xiao, Moon Kwon Han, Lewins Walter, Pallavi Garg, Didier Merlin

Sci Rep. 2016; 6: 27119. Published online 2016 Jun 1. doi: 10.1038/srep27119

PMCID:: PMC4890533

Abstract Article PDF–3.8M

Select item 48133806.

The proton‐coupled oligopeptide transporter 1 plays a major role in the intestinal permeability and absorption of 5‐aminolevulinic acid

Yehua Xie, Yongjun Hu, David E. Smith

Br J Pharmacol. 2016 Jan; 173(1): 167–176. Published online 2015 Nov 25. doi: 10.1111/bph.13356

PMCID:: PMC4813380

Abstract Article PDF–831K

Select item 41866767.

Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1

Yongjun Hu, Yehua Xie, Yuqing Wang, Xiaomei Chen, David E. Smith

Mol Pharm. 2014 Oct 6; 11(10): 3737–3746. Published online 2014 Aug 22. doi: 10.1021/mp500497p

PMCID:: PMC4186676

Abstract Article PDF–1.6M

Select item 38441018.

In Vivo Absorption and Disposition of Cefadroxil after Escalating Oral Doses in Wild-Type and PepT1 Knockout Mice

Maria M. Posada, David E. Smith

Pharm Res. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Pharm Res. 2013 Nov; 30(11): 10.1007/s11095-013-1168-3. doi: 10.1007/s11095-013-1168-3

PMCID:: PMC3844101

Abstract Article PDF–1.3M

Select item 37813779.

Impact of Peptide Transporter 1 on the Intestinal Absorption and Pharmacokinetics of Valacyclovir after Oral Dose Escalation in Wild-Type and PepT1 Knockout Mice

Bei Yang, Yongjun Hu, David E. Smith

Drug Metab Dispos. 2013 Oct; 41(10): 1867–1874. Published online 2013 Oct. doi: 10.1124/dmd.113.052597

PMCID:: PMC3781377

Abstract Article PDF–984K

Select item 358348810.

Significance of Peptide Transporter 1 in the Intestinal Permeability of Valacyclovir in Wild-Type and PepT1 Knockout Mice

Bei Yang, David E. Smith

Drug Metab Dispos. 2013 Mar; 41(3): 608–614. Published online 2013 Mar. doi: 10.1124/dmd.112.049239

PMCID:: PMC3583488

Abstract Article PDF–897K

Select item 325246011.

Influence of Fed-Fasted State on Intestinal PEPT1 Expression and In Vivo Pharmacokinetics of Glycylsarcosine in Wild-Type and Pept1 Knockout Mice

Ke Ma, Yongjun Hu, David E. Smith

Pharm Res. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Pharm Res. 2012 Feb; 29(2): 535–545. Published online 2011 Sep 9. doi: 10.1007/s11095-011-0580-9

PMCID:: PMC3252460

Abstract Article PDF–2.1M

Select item 319877312.

The Intestinal Peptide Transporter PEPT1 Is Involved in Food Intake Regulation in Mice Fed a High-Protein Diet

Anna-Maria Nässl, Isabel Rubio-Aliaga, Manuela Sailer, Hannelore Daniel

PLoS One. 2011; 6(10): e26407. Published online 2011 Oct 21. doi: 10.1371/journal.pone.0026407

PMCID:: PMC3198773

Abstract Article PDF–490K

Select item 301051813.

Peptide Transporter 1 is Responsible for Intestinal Uptake of the Dipeptide Glycylsarcosine: Studies in Everted Jejunal Rings from Wild-type and Pept1 Null Mice

Katherine Ma, Yongjun Hu, David E. Smith

J Pharm Sci. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: J Pharm Sci. 2011 Feb; 100(2): 767–774. Published online 2010 Sep 22. doi: 10.1002/jps.22277

PMCID:: PMC3010518

Abstract Article PDF–588K

Select item 277213214.

Targeted Disruption of Peptide Transporter Pept1 Gene in Mice Significantly Reduces Dipeptide Absorption in Intestine

Yongun Hu, David E. Smith, Ke Ma, Dilara Jappar, Winston Thomas, Kathleen M. Hillgren

Mol Pharm. Author manuscript; available in PMC 2009 Nov 3.

Published in final edited form as: Mol Pharm. 2008 Nov–Dec; 5(6): 1122–1130. doi: 10.1021/mp8001655

PMCID:: PMC2772132

Abstract Article PDF–2.9M

Select item 495795515.

Critical Role of PepT1 in Promoting Colitis-Associated Cancer and Therapeutic Benefits of the Anti-inflammatory PepT1-Mediated Tripeptide KPV in a Murine Model

Emilie Viennois, Sarah A. Ingersoll, Saravanan Ayyadurai, Yuan Zhao, Lixin Wang, Mingzhen Zhang, Moon K. Han, Pallavi Garg, Bo Xiao, Didier Merlin

Cell Mol Gastroenterol Hepatol. 2016 May; 2(3): 340–357. Published online 2016 Feb 16. doi: 10.1016/j.jcmgh.2016.01.006

PMCID:: PMC4957955

Abstract Article PDF–4.6M

Select item 482169116.

Species Differences in the Pharmacokinetics of Cefadroxil as Determined in Wildtype and Humanized PepT1 Mice

Yongjun Hu, David E. Smith

Biochem Pharmacol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Biochem Pharmacol. 2016 May 1; 107: 81–90. Published online 2016 Mar 12. doi: 10.1016/j.bcp.2016.03.008

PMCID:: PMC4821691

Abstract Article PDF–1.4M

Select item 459709117.

Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport

John H. Beale, Joanne L. Parker, Firdaus Samsudin, Anne L. Barrett, Anish Senan, Louise E. Bird, David Scott, Raymond J. Owens, Mark S.P. Sansom, Stephen J. Tucker, David Meredith, Philip W. Fowler, Simon Newstead

Structure. 2015 Oct 6; 23(10): 1889–1899. doi: 10.1016/j.str.2015.07.016