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Select item 48620411.

MEK5 overexpression is associated with the occurrence and development of colorectal cancer

Dechang Diao, Lei Wang, Jin Wan, Zhiqiang Chen, Junsheng Peng, Huanliang Liu, Xinlin Chen, Wei Wang, Liaonan Zou

BMC Cancer. 2016; 16: 302. Published online 2016 May 9. doi: 10.1186/s12885-016-2327-9

PMCID:: PMC4862041

Abstract Article PDF–2.5M

Select item 34598042.

The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children

Mathias Rask-Andersen, Josefin A Jacobsson, George Moschonis, Anna E Ek, George P Chrousos, Claude Marcus, Yannis Manios, Robert Fredriksson, Helgi B Schiöth

BMC Med Genet. 2012; 13: 36. Published online 2012 May 17. doi: 10.1186/1471-2350-13-36

PMCID:: PMC3459804

Abstract Article PDF–876K

Select item 33000743.

Mitogen/Extracellular Signal-Regulated Kinase Kinase-5 Promoter Region Polymorphisms Affect the Risk of Sporadic Colorectal Cancer in a Southern Chinese Population

Dechang Diao, Lei Wang, Jun-Xiao Zhang, Dianke Chen, Huanliang Liu, Yisheng Wei, Jiachun Lu, Junsheng Peng, Jianping Wang

DNA Cell Biol. 2012 Mar; 31(3): 341–348. doi: 10.1089/dna.2011.1232

PMCID:: PMC3300074

Abstract Article PDF–210K

Select item 10840324.

Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells

Dragomir Dinev, Bruce W. M. Jordan, Bernd Neufeld, Jiing-Dwan Lee, Dirk Lindemann, Ulf R. Rapp, Stephan Ludwig

EMBO Rep. 2001 Sep 15; 2(9): 829–834. doi: 10.1093/embo-reports/kve177

PMCID:: PMC1084032

Abstract Article PDF–1.1M

Select item 100354535.

MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells

Kazuya Fukasawa, Jiajun Lyu, Takuya Kubo, Yuki Tanaka, Akane Suzuki, Tetsuhiro Horie, Akane Tomizawa, Ryoma Osumi, Sayuki Iwahashi, Kazuya Tokumura, Misato Murata, Masaki Kobayashi, Tomoki Todo, Atsushi Hirao, Eiichi Hinoi

Cancer Res Commun. 2023 Jan; 3(1): 148–159. Published online 2023 Jan 30. doi: 10.1158/2767-9764.CRC-22-0243

PMCID:: PMC10035453

Abstract Article PDF–14M

Select item 78036106.

Identification of Novel Genetic Variants Related to Trabecular Bone Score in Community-Dwelling Older Adults

Sung Hye Kong, Ji Won Yoon, Jung Hee Kim, JooYong Park, Jiyeob Choi, Ji Hyun Lee, A Ram Hong, Nam H. Cho, Chan Soo Shin

Endocrinol Metab (Seoul) 2020 Dec; 35(4): 801–810. Published online 2020 Nov 24. doi: 10.3803/EnM.2020.735

PMCID:: PMC7803610

Abstract Article PDF–676K

Select item 70732797.

The MEK5-ERK5 kinase axis controls lipid metabolism in small cell lung cancer

Sandra Cristea, Garry L. Coles, Daniel Hornburg, Maya Gershkovitz, Julia Arand, Siqi Cao, Triparna Sen, Stuart C. Williamson, Jun W. Kim, Alexandros P. Drainas, Andrew He, Laurent Le Cam, Lauren A. Byers, Michael P. Snyder, Kévin Contrepois, Julien Sage

Cancer Res. Author manuscript; available in PMC 2020 Sep 15.

Published in final edited form as: Cancer Res. 2020 Mar 15; 80(6): 1293–1303. Published online 2020 Jan 22. doi: 10.1158/0008-5472.CAN-19-1027

PMCID:: PMC7073279

Abstract Article PDF–1.4M

Select item 63937658.

MEK5 promotes lung adenocarcinoma

Adrián Sánchez-Fdez, María Jesús Ortiz-Ruiz, María Florencia Re-Louhau, Isabel Ramos, Óscar Blanco-Múñez, Dolores Ludeña, Mar Abad, Manuel Sánchez-Martín, Atanasio Pandiella, Azucena Esparís-Ogando

Eur Respir J. 2019 Feb; 53(2): 1801327. Published online 2019 Feb 28. doi: 10.1183/13993003.01327-2018

PMCID:: PMC6393765

Abstract Article PDF–478K

Select item 54299249.

Extracellular Signal-Regulated Kinase 5 is Required for Low-Concentration H₂O₂-Induced Angiogenesis of Human Umbilical Vein Endothelial Cells

Shan Jiang, Dongxin Zhang, Hong Huang, Yonghong Lei, Yan Han, Weidong Han

Biomed Res Int. 2017; 2017: 6895730. Published online 2017 Apr 30. doi: 10.1155/2017/6895730

PMCID:: PMC5429924

Abstract Article PDF–3.8M

Select item 417441710.

The Effects of a MAP2K5 MicroRNA Target Site SNP on Risk for Anxiety and Depressive Disorders

Kevin P. Jensen, Henry R. Kranzler, Murray B. Stein, Joel Gelernter

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2014 Sep 24.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2014 Mar; 0(2): 175–183. Published online 2014 Jan 16. doi: 10.1002/ajmg.b.32219

PMCID:: PMC4174417

Abstract Article PDF–718K

Select item 122342311.

An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro.

Nimesh Mody, David G Campbell, Nick Morrice, Mark Peggie, Philip Cohen

Biochem J. 2003 Jun 1; 372(Pt 2): 567–575. doi: 10.1042/BJ20030193

PMCID:: PMC1223423

Summary PDF–242K

Select item 853898712.

The Hedgehog-GLI Pathway Regulates MEK5-ERK5 Expression and Activation in Melanoma Cells

Ignazia Tusa, Sinforosa Gagliardi, Alessandro Tubita, Silvia Pandolfi, Alessio Menconi, Matteo Lulli, Persio Dello Sbarba, Barbara Stecca, Elisabetta Rovida

Int J Mol Sci. 2021 Oct; 22(20): 11259. Published online 2021 Oct 19. doi: 10.3390/ijms222011259

PMCID:: PMC8538987

Abstract Article PDF–2.2M

Select item 462148513.

Genetic Associations of Periodic Limb Movements of Sleep in the Elderly, for the MrOS Sleep Study

John W Winkelman, Terri Blackwell, Katie Stone, Sonia Ancoli-Israel, Gregory J. Tranah, Susan Redline, the Osteoporotic Fractures in Men (MrOS) Study Research Group

Sleep Med. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Sleep Med. 2015 Nov; 16(11): 1360–1365. Published online 2015 Aug 11. doi: 10.1016/j.sleep.2015.07.017

PMCID:: PMC4621485

Abstract Article PDF–254K

Select item 413090814.

Identification of novel human kinases that suppress hepatitis C virus infection

A. Lee, S. Liu, T. Wang

J Viral Hepat. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: J Viral Hepat. 2014 Oct; 21(10): 716–726. Published online 2013 Nov 10. doi: 10.1111/jvh.12203

PMCID:: PMC4130908

Abstract Article PDF–1.8M

Select item 373978715.

MEK5/ERK5 Signaling Suppresses Estrogen Receptor Expression and Promotes Hormone-Independent Tumorigenesis

James W. Antoon, Elizabeth C. Martin, Rongye Lai, Virgilo A. Salvo, Yan Tang, Ashley M. Nitzchke, Steven Elliott, Seung Yoon Nam, Wei Xiong, Lyndsay V. Rhodes, Bridgette Collins-Burow, Odile David, Guandi Wang, Bin Shan, Barbara S. Beckman, Kenneth P. Nephew, Matthew E. Burow

PLoS One. 2013; 8(8): e69291. Published online 2013 Aug 9. doi: 10.1371/journal.pone.0069291