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Select item 59868071.

Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis

Shengli Pan, Yingying Deng, Jun Fu, Yuhao Zhang, Zhijin Zhang, Xiaokun Ru, Xianju Qin

Cell Death Dis. 2018 Jun; 9(6): 673. Published online 2018 Jun 4. doi: 10.1038/s41419-018-0707-6

PMCID:: PMC5986807

Article PDF–5.2M

Select item 58776652.

ARHGAP15 in Human Breast Carcinoma: A Potent Tumor Suppressor Regulated by Androgens

Kiyoshi Takagi, Yasuhiro Miki, Yoshiaki Onodera, Takanori Ishida, Mika Watanabe, Hironobu Sasano, Takashi Suzuki

Int J Mol Sci. 2018 Mar; 19(3): 804. Published online 2018 Mar 10. doi: 10.3390/ijms19030804

PMCID:: PMC5877665

Article PDF–3.0M

Select item 37743783.

ArhGAP15, a Rac-specific GTPase-activating Protein, Plays a Dual Role in Inhibiting Small GTPase Signaling

Maria Radu, Sonali J. Rawat, Alexander Beeser, Anton Iliuk, Weiguo Andy Tao, Jonathan Chernoff

J Biol Chem. 2013 Jul 19; 288(29): 21117–21125. Published online 2013 Jun 11. doi: 10.1074/jbc.M113.459719

PMCID:: PMC3774378

Article PDF–1.9M

Select item 54672054.

Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis

Snaevar Sigurdsson, Kristjan F. Alexandersson, Patrick Sulem, Bjarke Feenstra, Steinunn Gudmundsdottir, Gisli H. Halldorsson, Sigurgeir Olafsson, Asgeir Sigurdsson, Thorunn Rafnar, Thorgeir Thorgeirsson, Erik Sørensen, Andreas Nordholm-Carstensen, Jakob Burcharth, Jens Andersen, Henrik Stig Jørgensen, Emma Possfelt-Møller, Henrik Ullum, Gudmar Thorleifsson, Gisli Masson, Unnur Thorsteinsdottir, Mads Melbye, Daniel F. Gudbjartsson, Tryggvi Stefansson, Ingileif Jonsdottir, Kari Stefansson

Nat Commun. 2017; 8: 15789. Published online 2017 Jun 6. doi: 10.1038/ncomms15789

PMCID:: PMC5467205

Article PDF–822K

Select item 52768295.

Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway

Zhen Sun, Biao Zhang, Chen Wang, Tao Fu, Lianling Li, Qiaoli Wu, Ying Cai, Jinhuan Wang

Cancer Sci. 2017 Jan; 108(1): 61–72. Published online 2017 Jan 23. doi: 10.1111/cas.13118

PMCID:: PMC5276829

Article PDF–3.7M

Select item 76663716.

TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination

Li Xing, Xiaolong Tang, Kaikai Wu, Xiong Huang, Yi Yi, Jinliang Huan

Mol Ther Nucleic Acids. 2020 Dec 4; 22: 910–923. Published online 2020 Oct 15. doi: 10.1016/j.omtn.2020.10.012

PMCID:: PMC7666371

Article PDF–4.6M

Select item 31371407.

Haplotype Association Mapping of Acute Lung Injury in Mice Implicates Activin A Receptor, Type 1

George D. Leikauf, Vincent J. Concel, Pengyuan Liu, Kiflai Bein, Annerose Berndt, Koustav Ganguly, An Soo Jang, Kelly A. Brant, Maggie Dietsch, Hannah Pope-Varsalona, Richard A. Dopico, Jr., Y. P. Peter Di, Qian Li, Louis J. Vuga, Mario Medvedovic, Naftali Kaminski, Ming You, Daniel R. Prows

Am J Respir Crit Care Med. 2011 Jun 1; 183(11): 1499–1509. Published online 2011 Feb 4. doi: 10.1164/rccm.201006-0912OC

PMCID:: PMC3137140

Article PDF–1.8M

Select item 35973408.

Evidence for Genes on Chromosome 2 Contributing to Alcohol Dependence With Conduct Disorder and Suicide Attempts

Danielle M. Dick, Jacquelyn Meyers, Fazil Aliev, John Nurnberger, Jr., John Kramer, Sam Kuperman, Bernice Porjesz, Jay Tischfield, Howard J. Edenberg, Tatiana Foroud, Marc Schuckit, Alison Goate, Victor Hesselbrock, Laura Bierut

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2013 Mar 14.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Sep; 153B(6): 1179–1188. doi: 10.1002/ajmg.b.31089

PMCID:: PMC3597340

Article PDF–256K

Select item 26287359.

Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae

Jennifer K. Lowe, Julian B. Maller, Itsik Pe'er, Benjamin M. Neale, Jacqueline Salit, Eimear E. Kenny, Jessica L. Shea, Ralph Burkhardt, J. Gustav Smith, Weizhen Ji, Martha Noel, Jia Nee Foo, Maude L. Blundell, Vita Skilling, Laura Garcia, Marcia L. Sullivan, Heather E. Lee, Anna Labek, Hope Ferdowsian, Steven B. Auerbach, Richard P. Lifton, Christopher Newton-Cheh, Jan L. Breslow, Markus Stoffel, Mark J. Daly, David M. Altshuler, Jeffrey M. Friedman

PLoS Genet. 2009 Feb; 5(2): e1000365. Published online 2009 Feb 6. doi: 10.1371/journal.pgen.1000365

PMCID:: PMC2628735

Article PDF–377K

Select item 432144410.

Genome-wide association study of selenium concentrations

Marilyn C. Cornelis, Myriam Fornage, Millennia Foy, Pengcheng Xun, Vadim N. Gladyshev, Steve Morris, Daniel I. Chasman, Frank B. Hu, Eric B. Rimm, Peter Kraft, Joanne M. Jordan, Dariush Mozaffarian, Ka He

Hum Mol Genet. 2015 Mar 1; 24(5): 1469–1477. Published online 2014 Oct 24. doi: 10.1093/hmg/ddu546

PMCID:: PMC4321444

Article PDF–252K

Select item 404386811.

Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries

Zhen Zeng, Eleanor Feingold, Xiaojing Wang, Daniel E. Weeks, Myoungkeun Lee, Karen T. Cuenco, Barbara Broffitt, Robert J. Weyant, Richard Crout, Daniel W. McNeil, Steven M. Levy, Mary L. Marazita, John. R. Shaffer

Caries Res. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Caries Res. 2014; 48(4): 330–338. doi: 10.1159/000356299

PMCID:: PMC4043868

Article PDF–225K

Select item 671971812.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik

Nat Genet. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1

PMCID:: PMC6719718

Article PDF–1.3M

Select item 31093413.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Article PDF–1.3M

Select item 51531614.

Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions

Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano

Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604

PMCID:: PMC515316

Article PDF–181K

Select item 633346015.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Article PDF–2.7M

Select item 289646416.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Article PDF–2.4M

Select item 911973617.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Article PDF–3.3M

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Article PDF–2.7M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Article PDF–2.2M

Select item 13924120.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Article PDF–118K

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