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Select item 80484451.

A Novel Homozygous VPS11 Variant May Cause Generalized Dystonia

Edoardo Monfrini, Filippo Cogiamanian, Sabrina Salani, Letizia Straniero, Gigliola Fagiolari, Manuela Garbellini, Emma Carsana, Linda Borellini, Fabio Biella, Maurizio Moggio, Nereo Bresolin, Stefania Corti, Stefano Duga, Giacomo P. Comi, Massimo Aureli, Alessio Di Fonzo

Ann Neurol. 2021 Apr; 89(4): 834–839. Published online 2021 Feb 2. doi: 10.1002/ana.26021

PMCID:: PMC8048445

Abstract Article PDF–3.9M

Select item 50656052.

The second report of a new hypomyelinating disease due to a defect in the VPS11 gene discloses a massive lysosomal involvement

Konstanze Hörtnagel, Inge Krägeloh-Mann, Antje Bornemann, Miriam Döcker, Saskia Biskup, Heidi Mayrhofer, Florian Battke, Gabriele du Bois, Klaus Harzer

J Inherit Metab Dis. 2016; 39(6): 849–857. Published online 2016 Jul 29. doi: 10.1007/s10545-016-9961-x

PMCID:: PMC5065605

Abstract Article PDF–2.3M

Select item 48477783.

A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects

Jinglan Zhang, Véronik Lachance, Adam Schaffner, Xianting Li, Anastasia Fedick, Lauren E. Kaye, Jun Liao, Jill Rosenfeld, Naomi Yachelevich, Mary-Lynn Chu, Wendy G. Mitchell, Richard G. Boles, Ellen Moran, Mari Tokita, Elizabeth Gorman, Kaytee Bagley, Wei Zhang, Fan Xia, Magalie Leduc, Yaping Yang, Christine Eng, Lee-Jun Wong, Raphael Schiffmann, George A. Diaz, Ruth Kornreich, Ryan Thummel, Melissa Wasserstein, Zhenyu Yue, Lisa Edelmann

PLoS Genet. 2016 Apr; 12(4): e1005848. Published online 2016 Apr 27. doi: 10.1371/journal.pgen.1005848

PMCID:: PMC4847778

Abstract Article PDF–14M

Select item 64789104.

Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling

Gregory Segala, Marcela A. Bennesch, Nastaran Mohammadi Ghahhari, Deo Prakash Pandey, Pablo C. Echeverria, François Karch, Robert K. Maeda, Didier Picard

Nat Commun. 2019; 10: 1833. Published online 2019 Apr 23. doi: 10.1038/s41467-019-09800-y

PMCID:: PMC6478910

Abstract Article PDF–3.4M

Select item 35842825.

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

Salil Garg, Mahak Sharma, Cindy Ung, Amit Tuli, Duarte C. Barral, David L. Hava, Natacha Veerapen, Gurdyal S. Besra, Nir Hacohen, Michael B. Brenner

Immunity. 2011 Aug 26; 35(2): 182–193. doi: 10.1016/j.immuni.2011.06.009

PMCID:: PMC3584282

Abstract Article

Select item 56518186.

VPS18 recruits VPS41 to the human HOPS complex via a RING–RING interaction

Morag R. Hunter, Edward J. Scourfield, Edward Emmott, Stephen C. Graham

Biochem J. 2017 Nov 1; 474(21): 3615–3626. Prepublished online 2017 Sep 20. Published online 2017 Oct 23. doi: 10.1042/BCJ20170588

PMCID:: PMC5651818

Abstract Article PDF–6.5M

Select item 42509147.

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

Xiaosi Lin, Ting Yang, Shicong Wang, Zhen Wang, Ye Yun, Lixiang Sun, Yunhe Zhou, Xiaohui Xu, Chihiro Akazawa, Wanjin Hong, Tuanlao Wang

Sci Rep. 2014; 4: 7282. Published online 2014 Dec 2. doi: 10.1038/srep07282

Correction in:: Sci Rep. 2015; 5: 8302.

PMCID:: PMC4250914

Abstract Article PDF–1.8M

Select item 30314678.

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes

Dafne Chirivino, Laurence Del Maestro, Etienne Formstecher, Philippe Hupé, Graça Raposo, Daniel Louvard, Monique Arpin

Mol Biol Cell. 2011 Feb 1; 22(3): 375–385. doi: 10.1091/mbc.E10-09-0796

PMCID:: PMC3031467

Abstract Article PDF–7.0M

Select item 46832549.

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity

Rik van der Kant, Caspar T. H. Jonker, Ruud H. Wijdeven, Jeroen Bakker, Lennert Janssen, Judith Klumperman, Jacques Neefjes

J Biol Chem. 2015 Dec 18; 290(51): 30280–30290. Published online 2015 Oct 13. doi: 10.1074/jbc.M115.688440

PMCID:: PMC4683254

Abstract Article PDF–3.1M

Select item 398299710.

The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

Peidu Jiang, Taki Nishimura, Yuriko Sakamaki, Eisuke Itakura, Tomohisa Hatta, Tohru Natsume, Noboru Mizushima

Mol Biol Cell. 2014 Apr 15; 25(8): 1327–1337. doi: 10.1091/mbc.E13-08-0447

PMCID:: PMC3982997

Abstract Article PDF–8.1M

Select item 287871611.

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

Chengyu Liang, Jong-soo Lee, Kyung-Soo Inn, Michaela U. Gack, Qinglin Li, Esteban A. Roberts, Isabelle Vergne, Vojo Deretic, Pinghui Feng, Chihiro Akazawa, Jae U. Jung

Nat Cell Biol. Author manuscript; available in PMC 2010 May 31.

Published in final edited form as: Nat Cell Biol. 2008 Jul; 10(7): 776–787. Published online 2008 Jun 15. doi: 10.1038/ncb1740

PMCID:: PMC2878716

Abstract Article PDF–3.2M

Select item 537994312.

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

Rituraj Marwaha, Subhash B. Arya, Divya Jagga, Harmeet Kaur, Amit Tuli, Mahak Sharma

J Cell Biol. 2017 Apr 3; 216(4): 1051–1070. doi: 10.1083/jcb.201607085

PMCID:: PMC5379943

Abstract Article PDF–4.4M

Select item 374693713.

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

Stephen C. Graham, Lena Wartosch, Sally R. Gray, Edward J. Scourfield, Janet E. Deane, J. Paul Luzio, David J. Owen

Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33): 13345–13350. Published online 2013 Jul 30. doi: 10.1073/pnas.1307074110

PMCID:: PMC3746937

Abstract Article PDF–1.1M

Select item 451070614.

Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

Lena Wartosch, Ufuk Günesdogan, Stephen C. Graham, J. Paul Luzio

Traffic. 2015 Jul; 16(7): 727–742. Published online 2015 Apr 30. doi: 10.1111/tra.12283

PMCID:: PMC4510706

Abstract Article PDF–6.4M

Select item 783223515.

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

Guangyan Miao, Hongyu Zhao, Yan Li, Mingming Ji, Yong Chen, Yi Shi, Yuhai Bi, Peihui Wang, Hong Zhang

Dev Cell. 2021 Feb 22; 56(4): 427–442.e5. Published online 2020 Dec 16. doi: 10.1016/j.devcel.2020.12.010

PMCID:: PMC7832235

Abstract Article PDF–5.9M

Select item 264273916.

SPE-39 Family Proteins Interact with the HOPS Complex and Function in Lysosomal Delivery

Guang-dan Zhu, Gloria Salazar, Stephanie A. Zlatic, Babar Fiza, Michele M. Doucette, Craig J. Heilman, Allan I. Levey, Victor Faundez, Steven W. L'Hernault

Mol Biol Cell. 2009 Feb 15; 20(4): 1223–1240. doi: 10.1091/mbc.E08-07-0728

PMCID:: PMC2642739

Abstract Article PDF–1.4M

Select item 844759717.

Interactomes of SARS‐CoV‐2 and human coronaviruses reveal host factors potentially affecting pathogenesis

Zhen Chen, Chao Wang, Xu Feng, Litong Nie, Mengfan Tang, Huimin Zhang, Yun Xiong, Samuel K Swisher, Mrinal Srivastava, Junjie Chen

EMBO J. 2021 Sep 1; 40(17): e107776. Published online 2021 Jul 26. doi: 10.15252/embj.2021107776

PMCID:: PMC8447597

Abstract Article PDF–4.3M

Select item 295123518.

A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components

Carlos Gorbea, Gregory Pratt, Vicença Ustrell, Russell Bell, Sudhir Sahasrabudhe, Robert E. Hughes, Martin Rechsteiner

J Biol Chem. 2010 Oct 8; 285(41): 31616–31633. Published online 2010 Aug 3. doi: 10.1074/jbc.M110.154120

PMCID:: PMC2951235

Abstract Article PDF–6.3M

Select item 52484219.

Large-scale cDNA transfection screening for genes related to cancer development and progression

Dafang Wan, Yi Gong, Wenxin Qin, Pingping Zhang, Jinjun Li, Lin Wei, Xiaomei Zhou, Hongnian Li, Xiaokun Qiu, Fei Zhong, Liping He, Jian Yu, Genfu Yao, Huiqiu Jiang, Lianfang Qian, Ye Yu, Huiqun Shu, Xianlian Chen, Huili Xu, Minglei Guo, Zhimei Pan, Yan Chen, Chao Ge, Shengli Yang, Jianren Gu

Proc Natl Acad Sci U S A. 2004 Nov 2; 101(44): 15724–15729. Published online 2004 Oct 21. doi: 10.1073/pnas.0404089101

Correction in:: Proc Natl Acad Sci U S A. 2004 Dec 14; 101(50): 17565.

PMCID:: PMC524842

Abstract Article PDF–245K

Select item 339495220.

Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks

Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson

Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162

PMCID:: PMC3394952

Abstract Article PDF–3.3M

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PMC Links for Gene (Select 55823) (48)
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Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript...
Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 11, non-coding RNA
gi|1804894046|ref|NR_165451.1|

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