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Select item 99222501.

CDK5RAP2 is a Wnt target gene and promotes stemness and progression of oral squamous cell carcinoma

Yuehong Shen, Yuling Chen, Yuntao Lin, Yicun Li, Pengfei Liu, Biru Zhang, Yufan Wang, King-Chi Chan, Nai-Ki Mak, Michael Kahn, Robert Z. Qi, Hongyu Yang

Cell Death Dis. 2023 Feb; 14(2): 107. Published online 2023 Feb 11. doi: 10.1038/s41419-023-05652-z

PMCID:: PMC9922250

Article PDF–7.3M

Select item 75505862.

Cep215 is essential for morphological differentiation of astrocytes

Donghee Kang, Wonjung Shin, Hyunjeong Yoo, Seongjae Kim, Seongju Lee, Kunsoo Rhee

Sci Rep. 2020; 10: 17000. Published online 2020 Oct 12. doi: 10.1038/s41598-020-72728-7

PMCID:: PMC7550586

Article PDF–2.0M

Select item 53573053.

CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly

Salil K. Sukumaran, Maria Stumpf, Sarah Salamon, Ilyas Ahmad, Kurchi Bhattacharya, Sarah Fischer, Rolf Müller, Janine Altmüller, Birgit Budde, Holger Thiele, Muhammad Tariq, Naveed Altaf Malik, Peter Nürnberg, Shahid Mahmood Baig, Muhammad Sajid Hussain, Angelika A. Noegel

Mol Genet Genomics. 2017; 292(2): 365–383. Published online 2016 Dec 21. doi: 10.1007/s00438-016-1277-x

PMCID:: PMC5357305

Article PDF–8.0M

Select item 49298754.

Exome sequencing identifies recessive CDK5RAP2 variants in patients with isolated agenesis of corpus callosum

Loubna Jouan, Bouchra Ouled Amar Bencheikh, Hussein Daoud, Alexandre Dionne-Laporte, Sylvia Dobrzeniecka, Dan Spiegelman, Daniel Rochefort, Pascale Hince, Anna Szuto, Maryse Lassonde, Marine Barbelanne, William Y Tsang, Patrick A Dion, Hugo Théoret, Guy A Rouleau

Eur J Hum Genet. 2016 Apr; 24(4): 607–610. Published online 2015 Jul 22. doi: 10.1038/ejhg.2015.156

PMCID:: PMC4929875

Article PDF–671K

Select item 37142715.

Dynamic Recruitment of CDK5RAP2 to Centrosomes Requires Its Association with Dynein

Yue Jia, Ka-Wing Fong, Yuk-Kwan Choi, Siu-San See, Robert Z. Qi

PLoS One. 2013; 8(7): e68523. Published online 2013 Jul 17. doi: 10.1371/journal.pone.0068523

PMCID:: PMC3714271

Article PDF–772K

Select item 31008806.

Novel alternatively spliced variant form of human CDK5RAP2

Tom Kim, John SY Park, Paul Lee, Yan Jin, Song-bin Fu, Jesusa L Rosales, Ki-Young Lee

Cell Cycle. 2011 Mar 15; 10(6): 1010–1012. Published online 2011 Mar 15. doi: 10.4161/cc.10.6.15121

PMCID:: PMC3100880

Article PDF–860K

Select item 12881257.

A Third Novel Locus for Primary Autosomal Recessive Microcephaly Maps to Chromosome 9q34

Leanne Moynihan, Andrew P. Jackson, Emma Roberts, Gulshan Karbani, Ian Lewis, Peter Corry, Gwen Turner, Robert F. Mueller, Nicholas J. Lench, C. Geoffrey Woods

Am J Hum Genet. 2000 Feb; 66(2): 724–727. Published online 2000 Jan 19. doi: 10.1086/302777

PMCID:: PMC1288125

Article PDF–157K

Select item 86884698.

CDK5RAP2 loss-of-function causes premature cell senescence via the GSK3β/β-catenin-WIP1 pathway

Xidi Wang, Patrick Sipila, Zizhen Si, Jesusa L. Rosales, Xu Gao, Ki-Young Lee

Cell Death Dis. 2022 Jan; 13(1): 9. Published online 2021 Dec 20. doi: 10.1038/s41419-021-04457-2

PMCID:: PMC8688469

Article PDF–4.0M

Select item 76586999.

Centriole-independent mitotic spindle assembly relies on the PCNT–CDK5RAP2 pericentriolar matrix

Sadanori Watanabe, Franz Meitinger, Andrew K. Shiau, Karen Oegema, Arshad Desai

J Cell Biol. 2020 Dec 7; 219(12): e202006010. Published online 2020 Nov 10. doi: 10.1083/jcb.202006010

PMCID:: PMC7658699

Article PDF–6.1M

Select item 541806310.

Microtubule plus-end tracking of end-binding protein 1 (EB1) is regulated by CDK5 regulatory subunit-associated protein 2

Ka-Wing Fong, Franco K. C. Au, Yue Jia, Shaozhong Yang, Liying Zhou, Robert Z. Qi

J Biol Chem. 2017 May 5; 292(18): 7675–7687. Published online 2017 Mar 20. doi: 10.1074/jbc.M116.759746

PMCID:: PMC5418063

Article PDF–4.9M

Select item 480205611.

A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer

Pavithra L. Chavali, Gayathri Chandrasekaran, Alexis R. Barr, Péter Tátrai, Chris Taylor, Evaggelia K. Papachristou, C. Geoffrey Woods, Sreenivas Chavali, Fanni Gergely

Nat Commun. 2016; 7: 11005. Published online 2016 Mar 18. doi: 10.1038/ncomms11005

PMCID:: PMC4802056

Article PDF–4.1M

Select item 389937012.

Importance of the CEP215-Pericentrin Interaction for Centrosome Maturation during Mitosis

Seongjae Kim, Kunsoo Rhee

PLoS One. 2014; 9(1): e87016. Published online 2014 Jan 22. doi: 10.1371/journal.pone.0087016

PMCID:: PMC3899370

Article PDF–1.1M

Select item 207294513.

Previously described sequence variant in CDK5RAP2 gene in a Pakistani family with autosomal recessive primary microcephaly

Muhammad Jawad Hassan, Maryam Khurshid, Zahid Azeem, Peter John, Ghazanfar Ali, Muhammad Salman Chishti, Wasim Ahmad

BMC Med Genet. 2007; 8: 58. Published online 2007 Sep 1. doi: 10.1186/1471-2350-8-58

PMCID:: PMC2072945

Article PDF–329K

Select item 835466214.

Triple deletion of TP53, PCNT, and CEP215 promotes centriole amplification in the M phase

Gee In Jung, Kunsoo Rhee

Cell Cycle. 2021; 20(15): 1500–1517. Published online 2021 Jul 8. doi: 10.1080/15384101.2021.1950386

PMCID:: PMC8354662

Article PDF–3.2M

Select item 573357915.

The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins

Elena Kolobova, Joseph T. Roland, Lynne A. Lapierre, Janice A. Williams, Twila A. Mason, James R. Goldenring

J Biol Chem. 2017 Dec 15; 292(50): 20394–20409. Published online 2017 Oct 20. doi: 10.1074/jbc.M117.806018

PMCID:: PMC5733579

Article PDF–4.2M

Select item 463835016.

Species-Specific Expression of Full-Length and Alternatively Spliced Variant Forms of CDK5RAP2

John S. Y. Park, Marie-Katrina Lee, SungMyung Kang, Yan Jin, Songbin Fu, Jesusa L. Rosales, Ki-Young Lee

PLoS One. 2015; 10(11): e0142577. Published online 2015 Nov 9. doi: 10.1371/journal.pone.0142577

PMCID:: PMC4638350

Article PDF–1.8M

Select item 382084217.

CDK5RAP2 is required for spindle checkpoint function

Xiaoying Zhang, Dongyun Liu, Shuang Lv, Haibo Wang, Xueyan Zhong, Bo Liu, Bo Wang, Ji Liao, Jing Li, Gerd P. Pfeifer, Xingzhi Xu

Cell Cycle. 2009 Apr 15; 8(8): 1206–1216. doi: 10.4161/cc.8.8.8205

PMCID:: PMC3820842

Article PDF–918K

Select item 363919518.

Clinical and cellular features in patients with primary autosomal recessive microcephaly and a novel CDK5RAP2 mutation

Lina Issa, Katrin Mueller, Katja Seufert, Nadine Kraemer, Henning Rosenkotter, Olaf Ninnemann, Michael Buob, Angela M Kaindl, Deborah J Morris-Rosendahl

Orphanet J Rare Dis. 2013; 8: 59. Published online 2013 Apr 15. doi: 10.1186/1750-1172-8-59