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Select item 79574271.

NHP2 downregulation counteracts hTR‐mediated activation of the DNA damage response at ALT telomeres

Maya Raghunandan, Dan Geelen, Eva Majerova, Anabelle Decottignies

EMBO J. 2021 Mar 15; 40(6): e106336. Published online 2021 Feb 17. doi: 10.15252/embj.2020106336

PMCID:: PMC7957427

Abstract Article PDF–2.4M

Select item 55793922.

Control of box C/D snoRNP assembly by N⁶‐methylation of adenine

Lin Huang, Saira Ashraf, Jia Wang, David MJ Lilley

EMBO Rep. 2017 Sep; 18(9): 1631–1645. Published online 2017 Jun 16. doi: 10.15252/embr.201743967

PMCID:: PMC5579392

Abstract Article PDF–1.7M

Select item 24303613.

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

Tom Vulliamy, Richard Beswick, Michael Kirwan, Anna Marrone, Martin Digweed, Amanda Walne, Inderjeet Dokal

Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23): 8073–8078. Published online 2008 Jun 3. doi: 10.1073/pnas.0800042105

PMCID:: PMC2430361

Abstract Article PDF–548K

Select item 26487024.

Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP

Christian Trahan, François Dragon

RNA. 2009 Feb; 15(2): 235–243. doi: 10.1261/rna.1354009

PMCID:: PMC2648702

Abstract Article PDF–1.0M

Select item 3942355.

Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins

Chen Wang, U Thomas Meier

EMBO J. 2004 Apr 21; 23(8): 1857–1867. Published online 2004 Mar 25. doi: 10.1038/sj.emboj.7600181

PMCID:: PMC394235

Abstract Article PDF–343K

Select item 865566.

Human H/ACA Small Nucleolar RNPs and Telomerase Share Evolutionarily Conserved Proteins NHP2 and NOP10

Vanda Pogacic, François Dragon, Witold Filipowicz

Mol Cell Biol. 2000 Dec; 20(23): 9028–9040. doi: 10.1128/mcb.20.23.9028-9040.2000

PMCID:: PMC86556

Abstract Article PDF–4.1M

Select item 34344837.

An Enhanced H/ACA RNP Assembly Mechanism for Human Telomerase RNA

Emily D. Egan, Kathleen Collins

Mol Cell Biol. 2012 Jul; 32(13): 2428–2439. doi: 10.1128/MCB.00286-12

PMCID:: PMC3434483

Abstract Article PDF–2.5M

Select item 62231298.

Cryo-EM structure of substrate-bound human telomerase holoenzyme

Thi Hoang Duong Nguyen, Jane Tam, Robert A. Wu, Basil J. Greber, Daniel Toso, Eva Nogales, Kathleen Collins

Nature. Author manuscript; available in PMC 2018 Nov 8.

Published in final edited form as: Nature. 2018 May; 557(7704): 190–195. Published online 2018 Apr 25. doi: 10.1038/s41586-018-0062-x

PMCID:: PMC6223129

Abstract Article PDF–5.0M

Select item 11710559.

Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.

A Henras, Y Henry, C Bousquet-Antonelli, J Noaillac-Depeyre, J P Gélugne, M Caizergues-Ferrer

EMBO J. 1998 Dec 1; 17(23): 7078–7090. doi: 10.1093/emboj/17.23.7078

PMCID:: PMC1171055

Summary PDF–551K

Select item 429477610.

Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance

Mengfan Tang, Yujing Li, Yi Zhang, Yuxi Chen, Wenjun Huang, Dan Wang, Arthur J. Zaug, Dan Liu, Yong Zhao, Thomas R. Cech, Wenbin Ma, Zhou Songyang

J Cell Sci. 2015 Jan 15; 128(2): 331–341. doi: 10.1242/jcs.159467

PMCID:: PMC4294776

Abstract Article

Select item 287652111.

Specificity and Stoichiometry of Subunit Interactions in the Human Telomerase Holoenzyme Assembled In Vivo

Emily D. Egan, Kathleen Collins

Mol Cell Biol. 2010 Jun; 30(11): 2775–2786. Published online 2010 Mar 29. doi: 10.1128/MCB.00151-10

PMCID:: PMC2876521

Abstract Article PDF–2.0M

Select item 460239812.

Cell fate determination by ubiquitin-dependent regulation of translation

Achim Werner, Shintaro Iwasaki, Colleen McGourty, Sofia Medina-Ruiz, Nia Teerikorpi, Indro Fedrigo, Nicholas T. Ingolia, Michael Rape

Nature. Author manuscript; available in PMC 2016 Mar 24.

Published in final edited form as: Nature. 2015 Sep 24; 525(7570): 523–527. doi: 10.1038/nature14978

PMCID:: PMC4602398

Abstract Article PDF–4.4M

Select item 541684213.

The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain

Graeme R. Wells, Franziska Weichmann, Katherine E. Sloan, David Colvin, Nicholas J. Watkins, Claudia Schneider

Nucleic Acids Res. 2017 May 5; 45(8): 4796–4809. Published online 2017 Jan 13. doi: 10.1093/nar/gkw1344

PMCID:: PMC5416842

Abstract Article PDF–5.9M

Select item 818341414.

The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis

Hyunju Ryu, Xiao‐Xin Sun, Yingxiao Chen, Yanping Li, Xiaoyan Wang, Roselyn S Dai, Hong‐Ming Zhu, John Klimek, Larry David, Lev M Fedorov, Yoshiaki Azuma, Rosalie C Sears, Mu‐Shui Dai

EMBO Rep. 2021 Jun 4; 22(6): e50684. Published online 2021 Apr 14. doi: 10.15252/embr.202050684

PMCID:: PMC8183414

Abstract Article PDF–2.1M

Select item 291759515.

Purification of Human Telomerase Complexes Identifies Factors Involved in Telomerase Biogenesis and Telomere Length Regulation

Dragony Fu, Kathleen Collins

Mol Cell. Author manuscript; available in PMC 2010 Aug 7.

Published in final edited form as: Mol Cell. 2007 Dec 14; 28(5): 773–785. doi: 10.1016/j.molcel.2007.09.023

PMCID:: PMC2917595

Abstract Article PDF–2.1M

Select item 432914316.

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1

Adam Freund, Franklin L. Zhong, Andrew S. Venteicher, Zhaojing Meng, Timothy D. Veenstra, Judith Frydman, Steven E. Artandi

Cell. Author manuscript; available in PMC 2015 Dec 4.

Published in final edited form as: Cell. 2014 Dec 4; 159(6): 1389–1403. Published online 2014 Nov 20. doi: 10.1016/j.cell.2014.10.059

PMCID:: PMC4329143

Abstract Article PDF–1.4M

Select item 368073217.

HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

Dennis Kappei, Falk Butter, Christian Benda, Marion Scheibe, Irena Draškovič, Michelle Stevense, Clara Lopes Novo, Claire Basquin, Masatake Araki, Kimi Araki, Dragomir Blazhev Krastev, Ralf Kittler, Rolf Jessberger, J Arturo Londoño-Vallejo, Matthias Mann, Frank Buchholz

EMBO J. 2013 Jun 12; 32(12): 1681–1701. Published online 2013 May 17. doi: 10.1038/emboj.2013.105

PMCID:: PMC3680732

Abstract Article PDF–1.6M

Select item 669984818.

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding

Xiaoxiao Huang, Richard D. LeDuc, Luca Fornelli, Alissa J. Schunter, Richard L. Bennett, Neil L. Kelleher, Jonathan D. Licht

J Biol Chem. 2019 Aug 16; 294(33): 12459–12471. Published online 2019 Jun 27. doi: 10.1074/jbc.RA118.006159

PMCID:: PMC6699848

Abstract Article PDF–2.1M

Select item 449239319.

Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations

Frederic F. Depreux, Megan J. Puckelwartz, Aleksandra Augustynowicz, Don Wolfgeher, Christine M. Labno, Dynora Pierre-Louis, Danielle Cicka, Stephen J. Kron, James Holaska, Elizabeth M. McNally

Hum Mol Genet. 2015 Aug 1; 24(15): 4284–4295. Published online 2015 May 6. doi: 10.1093/hmg/ddv160

PMCID:: PMC4492393

Abstract Article PDF–1.0M

Select item 280833220.

Expanding the Substantial Interactome of NEMO Using Protein Microarrays

Beau J. Fenner, Michael Scannell, Jochen H. M. Prehn

PLoS One. 2010; 5(1): e8799. Published online 2010 Jan 20. doi: 10.1371/journal.pone.0008799

PMCID:: PMC2808332

Abstract Article PDF–509K

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PMC Links for Gene (Select 55651) (93)
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proline--tRNA ligase [Psychroserpens sp. NJDZ02]
proline--tRNA ligase [Psychroserpens sp. NJDZ02]
gi|1624183916|gnl|PRJNA533249|E9099 0|gb|QCE41980.1|

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