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Items: 1 to 20 of 89

1.
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1
Zhiping Jiang, Ao Zhang, Wenjia Wei, Shujun Li
Sci Rep. 2023; 13: 8389. Published online 2023 May 24. doi: 10.1038/s41598-023-35096-6
PMCID:
PMC10209061
AbstractArticlePDF–9.2M
2.
The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
Matteo Tiberti, Luca Di Leo, Mette Vixø Vistesen, Rikke Sofie Kuhre, Francesco Cecconi, Daniela De Zio, Elena Papaleo
Cell Death Dis. 2022 Oct; 13(10): 872. Published online 2022 Oct 15. doi: 10.1038/s41419-022-05318-2
PMCID:
PMC9569343
AbstractArticlePDF–3.4M
3.
The Long-Lost Ligase: CRL4AMBRA1 Regulates the Stability of D-Type Cyclins
Andrea C. Chaikovsky, Julien Sage, Michele Pagano, Daniele Simoneschi
DNA Cell Biol. December 2021; 40(12): 1457–1461. Published online 2021 Dec 16. doi: 10.1089/dna.2021.0659
PMCID:
PMC8742259
AbstractArticlePDF–304K
4.
HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1
Manuela Antonioli, Benedetta Pagni, Tiziana Vescovo, Rob Ellis, Benjamin Cosway, Francesca Rollo, Veronica Bordoni, Chiara Agrati, Marie Labus, Renato Covello, Maria Benevolo, Giuseppe Ippolito, Max Robinson, Mauro Piacentini, Penny Lovat, Gian Maria Fimia
Autophagy. 2021; 17(10): 2842–2855. Published online 2020 Nov 23. doi: 10.1080/15548627.2020.1847444
PMCID:
PMC8526016
AbstractArticlePDF–3.6M
5.
Ambra1 induces autophagy and desensitizes human prostate cancer cells to cisplatin
Jie Liu, Zhiyuan Chen, Jia Guo, Lei Wang, Xiuheng Liu
Biosci Rep. 2019 Aug 30; 39(8): BSR20170770. Prepublished online 2017 Nov 3. Published online 2019 Aug 23. doi: 10.1042/BSR20170770
PMCID:
PMC6706594
AbstractArticlePDF–1.1M
6.
Prolonged Pseudohypoxia Targets Ambra1 mRNA to P-Bodies for Translational Repression
Somayeh Pourpirali, Cristina Valacca, Paola Merlo, Salvatore Rizza, Silvia D’Amico, Francesco Cecconi
PLoS One. 2015; 10(6): e0129750. Published online 2015 Jun 18. doi: 10.1371/journal.pone.0129750
PMCID:
PMC4473010
AbstractArticlePDF–4.2M
7.
Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response
V Pagliarini, E Wirawan, A Romagnoli, F Ciccosanti, G Lisi, S Lippens, F Cecconi, G M Fimia, P Vandenabeele, M Corazzari, M Piacentini
Cell Death Differ. 2012 Sep; 19(9): 1495–1504. Published online 2012 Mar 23. doi: 10.1038/cdd.2012.27
PMCID:
PMC3422474
AbstractArticlePDF–784K
8.
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling
Francesca Nazio, Agnese Po, Luana Abballe, Claudio Ballabio, Francesca Diomedi Camassei, Matteo Bordi, Antonio Camera, Simona Caruso, Ignazio Caruana, Marco Pezzullo, Caterina Ferraina, Giacomo Milletti, Matteo Gianesello, Sofia Reddel, Carmen Dolores De Luca, Donatella Ceglie, Sara Marinelli, Silvia Campello, Elena Papaleo, Evelina Miele, Antonella Cacchione, Andrea Carai, Maria Vinci, Enrico Velardi, Biagio De Angelis, Luca Tiberi, Concetta Quintarelli, Angela Mastronuzzi, Elisabetta Ferretti, Franco Locatelli, Francesco Cecconi
Acta Neuropathol. 2021; 142(3): 537–564. Published online 2021 Jul 24. doi: 10.1007/s00401-021-02347-7
PMCID:
PMC8357694
AbstractArticlePDF–8.7M
9.
The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes
Christina Schoenherr, Adam Byron, Billie Griffith, Alexander Loftus, Jimi C. Wills, Alison F. Munro, Alex von Kriegsheim, Margaret C. Frame
J Biol Chem. 2020 Aug 21; 295(34): 12045–12057. Published online 2020 Jul 2. doi: 10.1074/jbc.RA120.012565
PMCID:
PMC7443501
AbstractArticlePDF–3.4M
10.
Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas
R. Ellis, D. Tang, B. Nasr, A. Greenwood, A. McConnell, M.E. Anagnostou, M. Elias, S. Verykiou, D. Bajwa, T. Ewen, N.J. Reynolds, P. Barrett, E. Carling, G. Watson, J. Armstrong, A.J. Allen, S. Horswell, M. Labus, P.E. Lovat
Br J Dermatol. 2020 Jan; 182(1): 156–165. Published online 2019 Jun 19. doi: 10.1111/bjd.18086
PMCID:
PMC6973157
AbstractArticlePDF–3.8M
11.
Ambra1 modulates the sensitivity of breast cancer cells to epirubicin by regulating autophagy via ATG12
Wei‐Liang Sun, Li Wang, Jie Luo, Hua‐Wei Zhu, Zheng‐Wen Cai
Cancer Sci. 2018 Oct; 109(10): 3129–3138. Published online 2018 Aug 24. doi: 10.1111/cas.13743
PMCID:
PMC6172055
AbstractArticlePDF–1.3M
12.
Sexual dimorphism of AMBRA1-related autistic features in human and mouse
M Mitjans, M Begemann, A Ju, E Dere, L Wüstefeld, S Hofer, I Hassouna, J Balkenhol, B Oliveira, S van der Auwera, R Tammer, K Hammerschmidt, H Völzke, G Homuth, F Cecconi, K Chowdhury, H Grabe, J Frahm, S Boretius, T Dandekar, H Ehrenreich
Transl Psychiatry. 2017 Oct; 7(10): e1247. Published online 2017 Oct 10. doi: 10.1038/tp.2017.213
PMCID:
PMC5682605
AbstractArticlePDF–2.7M
13.
AMBRA1 and BECLIN 1 interplay in the crosstalk between autophagy and cell proliferation
Valentina Cianfanelli, Melania D'Orazio, Francesco Cecconi
Cell Cycle. 2015 Apr 1; 14(7): 959–963. Published online 2015 Mar 24. doi: 10.1080/15384101.2015.1021526
PMCID:
PMC4615147
AbstractArticlePDF–252K
14.
AMBRA1 and SQSTM1 expression pattern in prostate cancer
Laura Falasca, Francesco Torino, Matteo Marconi, Manuela Costantini, Vincenzo Pompeo, Steno Sentinelli, Laura De Salvo, Mario Patrizio, Cristiano Padula, Michele Gallucci, Mauro Piacentini, Walter Malorni
Apoptosis. 2015; 20(12): 1577–1586. Published online 2015 Sep 30. doi: 10.1007/s10495-015-1176-3
PMCID:
PMC4602066
AbstractArticlePDF–1.5M
15.
Ambra1 Is an Essential Regulator of Autophagy and Apoptosis in SW620 Cells: Pro-Survival Role of Ambra1
Wen Gu, Daiwei Wan, Qinyi Qian, Bin Yi, Zhilong He, Yilin Gu, Liang Wang, Songbing He
PLoS One. 2014; 9(2): e90151. Published online 2014 Feb 26. doi: 10.1371/journal.pone.0090151
PMCID:
PMC3936000
AbstractArticlePDF–5.7M
16.
HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy
Flavie Strappazzon, Anthea Di Rita, Angelo Peschiaroli, Pier Paolo Leoncini, Franco Locatelli, Gerry Melino, Francesco Cecconi
Cell Death Differ. 2020 Apr; 27(4): 1155–1168. Published online 2019 Aug 21. doi: 10.1038/s41418-019-0404-8
Correction in:
Cell Death Differ. 2020 May; 27(5): 1745–1746.
PMCID:
PMC7206129
AbstractArticlePDF–2.4M
17.
MIR7–3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1
Mariacristina Capizzi, Flavie Strappazzon, Valentina Cianfanelli, Elena Papaleo, Francesco Cecconi
Autophagy. 2017; 13(3): 554–566. Published online 2017 Jan 6. doi: 10.1080/15548627.2016.1269989
PMCID:
PMC5361610
AbstractArticlePDF–1012K
18.
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy
Flavie Strappazzon, Matteo Vietri-Rudan, Silvia Campello, Francesca Nazio, Fulvio Florenzano, Gian Maria Fimia, Mauro Piacentini, Beth Levine, Francesco Cecconi
EMBO J. 2011 Apr 6; 30(7): 1195–1208. Published online 2011 Feb 25. doi: 10.1038/emboj.2011.49
PMCID:
PMC3094111
AbstractArticlePDF–1.9M
19.
AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability
Martina Di Rienzo, Alessandra Romagnoli, Fabiola Ciccosanti, Giulia Refolo, Veronica Consalvi, Giuseppe Arena, Enza Maria Valente, Mauro Piacentini, Gian Maria Fimia
Autophagy. 2022; 18(8): 1752–1762. Published online 2021 Nov 19. doi: 10.1080/15548627.2021.1997052
PMCID:
PMC9450973
AbstractArticlePDF–1.3M
20.
AMBRA1 Negatively Regulates the Function of ALDH1B1, a Cancer Stem Cell Marker, by Controlling Its Ubiquitination
Seung-Heon Baek, Yeun-Kyu Jang
Int J Mol Sci. 2021 Nov; 22(21): 12079. Published online 2021 Nov 8. doi: 10.3390/ijms222112079
PMCID:
PMC8584921
AbstractArticlePDF–9.5M

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