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Select item 108056021.

A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells

Megan M. Schmit, Ryan M. Baxley, Liangjun Wang, Peter Hinderlie, Marissa Kaufman, Emily Simon, Anjali Raju, Jeffrey S. Miller, Anja-Katrin Bielinsky

Open Biol. 2024 Jan; 14(1): 230407. Published online January 24, 2024. doi: 10.1098/rsob.230407

PMCID:: PMC10805602

Abstract Article PDF–9.4M

Select item 105820702.

MCM10, a potential diagnostic, immunological, and prognostic biomarker in pan-cancer

Dengwang Chen, Na Zhong, Zhanwen Guo, Qinglu Ji, Zixuan Dong, Jishan Zheng, Yunyan Ma, Jidong Zhang, Yuqi He, Tao Song

Sci Rep. 2023; 13: 17701. Published online 2023 Oct 17. doi: 10.1038/s41598-023-44946-2

PMCID:: PMC10582070

Abstract Article PDF–4.9M

Select item 94337243.

Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation

Madison Caballero, Tiffany Ge, Ana Rita Rebelo, Seungmae Seo, Sean Kim, Kayla Brooks, Michael Zuccaro, Radhakrishnan Kanagaraj, Dan Vershkov, Dongsung Kim, Agata Smogorzewska, Marcus Smolka, Nissim Benvenisty, Stephen C West, Dieter Egli, Emily M Mace, Amnon Koren

Hum Mol Genet. 2022 Sep 1; 31(17): 2899–2917. Published online 2022 Apr 8. doi: 10.1093/hmg/ddac082

PMCID:: PMC9433724

Abstract Article PDF–2.2M

Select item 92544704.

Over-Activation of Minichromosome Maintenance Protein 10 Promotes Genomic Instability in Early Stages of Breast Cancer

Muhammad Jameel Mughal, Kin Iong Chan, Ravikiran Mahadevappa, Sin Wa Wong, Kit Cheng Wai, Hang Fai Kwok

Int J Biol Sci. 2022; 18(9): 3827–3844. Published online 2022 May 29. doi: 10.7150/ijbs.69344

PMCID:: PMC9254470

Abstract Article PDF–2.4M

Select item 82361225.

Aberrant MCM10 SUMOylation induces genomic instability mediated by a genetic variant associated with survival of esophageal squamous cell carcinoma

Jianbo Tian, Zequn Lu, Siyuan Niu, Shanshan Zhang, Pingting Ying, Lu Wang, Ming Zhang, Yimin Cai, Tianyi Dong, Ying Zhu, Rong Zhong, Zhihua Wang, Jiang Chang, Xiaoping Miao

Clin Transl Med. 2021 Jun; 11(6): e485. Published online 2021 Jun 27. doi: 10.1002/ctm2.485

PMCID:: PMC8236122

Abstract Article PDF–7.8M

Select item 79550846.

Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening

Ryan M. Baxley, Wendy Leung, Megan M. Schmit, Jacob Peter Matson, Lulu Yin, Marissa K. Oram, Liangjun Wang, John Taylor, Jack Hedberg, Colette B. Rogers, Adam J. Harvey, Debashree Basu, Jenny C. Taylor, Alistair T. Pagnamenta, Helene Dreau, Jude Craft, Elizabeth Ormondroyd, Hugh Watkins, Eric A. Hendrickson, Emily M. Mace, Jordan S. Orange, Hideki Aihara, Grant S. Stewart, Edward Blair, Jeanette Gowen Cook, Anja-Katrin Bielinsky

Nat Commun. 2021; 12: 1626. Published online 2021 Mar 12. doi: 10.1038/s41467-021-21878-x

PMCID:: PMC7955084

Abstract Article PDF–7.1M

Select item 75244767.

Human NK cell deficiency as a result of biallelic mutations in MCM10

Emily M. Mace, Silke Paust, Matilde I. Conte, Ryan M. Baxley, Megan M. Schmit, Sagar L. Patil, Nicole C. Guilz, Malini Mukherjee, Ashley E. Pezzi, Jolanta Chmielowiec, Swetha Tatineni, Ivan K. Chinn, Zeynep Coban Akdemir, Shalini N. Jhangiani, Donna M. Muzny, Asbjørg Stray-Pedersen, Rachel E. Bradley, Mo Moody, Philip P. Connor, Adrian G. Heaps, Colin Steward, Pinaki P. Banerjee, Richard A. Gibbs, Malgorzata Borowiak, James R. Lupski, Stephen Jolles, Anja K. Bielinsky, Jordan S. Orange

J Clin Invest. 2020 Oct 1; 130(10): 5272–5286. Published online 2020 Aug 31. doi: 10.1172/JCI134966

PMCID:: PMC7524476

Abstract Article PDF–4.2M

Select item 62829498.

Overexpression of MCM10 promotes cell proliferation and predicts poor prognosis in prostate cancer

Feilun Cui, Jianpeng Hu, Songyi Ning, Jian Tan, Huaming Tang

Prostate. 2018 Dec 1; 78(16): 1299–1310. Published online 2018 Aug 10. doi: 10.1002/pros.23703

PMCID:: PMC6282949

Abstract Article PDF–6.4M

Select item 50232799.

Structural Biology of Replication Initiation Factor Mcm10

Wenyue Du, Melissa E. Stauffer, Brandt F. Eichman

Subcell Biochem. Author manuscript; available in PMC 2016 Sep 14.

Published in final edited form as: Subcell Biochem. 2012; 62: 197–216. doi: 10.1007/978-94-007-4572-8_11

PMCID:: PMC5023279

Abstract Article PDF–1.4M

Select item 404389010.

MCM10: one tool for all - integrity, maintenance and damage control

Yee Mon Thu, Anja-Katrin Bielinsky

Semin Cell Dev Biol. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Semin Cell Dev Biol. 2014 Jun; 0: 121–130. Published online 2014 Mar 21. doi: 10.1016/j.semcdb.2014.03.017

PMCID:: PMC4043890

Abstract Article PDF–826K

Select item 283298511.

Ultraviolet Radiation Stress Triggers the Down-regulation of Essential Replication Factor Mcm10

Aparna Sharma, Manpreet Kaur, Ananya Kar, Sourabh M. Ranade, Sandeep Saxena

J Biol Chem. 2010 Mar 12; 285(11): 8352–8362. Published online 2010 Jan 11. doi: 10.1074/jbc.M109.041129

PMCID:: PMC2832985

Abstract Article PDF–2.8M

Select item 793578312.

MCM10 compensates for Myc‐induced DNA replication stress in breast cancer stem‐like cells

Takahiko Murayama, Yasuto Takeuchi, Kaoru Yamawaki, Toyoaki Natsume, Mengjiao Li, Rojas‐Chaverra N. Marcela, Tatsunori Nishimura, Yuta Kogure, Asuka Nakata, Kana Tominaga, Asako Sasahara, Masao Yano, Satoko Ishikawa, Tetsuo Ohta, Kazuhiro Ikeda, Kuniko Horie‐Inoue, Satoshi Inoue, Masahide Seki, Yutaka Suzuki, Sumio Sugano, Takayuki Enomoto, Masahiko Tanabe, Kei‐ichiro Tada, Masato T. Kanemaki, Koji Okamoto, Arinobu Tojo, Noriko Gotoh

Cancer Sci. 2021 Mar; 112(3): 1209–1224. Published online 2021 Jan 22. doi: 10.1111/cas.14776

PMCID:: PMC7935783

Abstract Article PDF–2.3M

Select item 536362013.

MCM10 overexpression implicates adverse prognosis in urothelial carcinoma

Wei-Ming Li, Chun-Nung Huang, Hung-Lung Ke, Ching-Chia Li, Yu-Ching Wei, Hsin-Chih Yeh, Lin-Li Chang, Chun-Hsiung Huang, Peir-In Liang, Bi-Wen Yeh, Ti-Chun Chan, Chien-Feng Li, Wen-Jeng Wu

Oncotarget. 2016 Nov 22; 7(47): 77777–77792. Published online 2016 Oct 21. doi: 10.18632/oncotarget.12795

PMCID:: PMC5363620

Abstract Article PDF–4.6M

Select item 362760314.

Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation

Samuel T. Fatoba, Silvia Tognetti, Melissa Berto, Elisabetta Leo, Claire M. Mulvey, Jasminka Godovac-Zimmermann, Yves Pommier, Andrei L. Okorokov

Nucleic Acids Res. 2013 Apr; 41(7): 4065–4079. Published online 2013 Feb 28. doi: 10.1093/nar/gkt131

PMCID:: PMC3627603

Abstract Article PDF–2.7M

Select item 278205515.

Physical Interactions between Mcm10, DNA, and DNA Polymerase α

Eric M. Warren, Hao Huang, Ellen Fanning, Walter J. Chazin, Brandt F. Eichman

J Biol Chem. 2009 Sep 4; 284(36): 24662–24672. Published online 2009 Jul 16. doi: 10.1074/jbc.M109.020438

PMCID:: PMC2782055

Abstract Article PDF–3.4M

Select item 200255316.

Hexameric ring structure of human MCM10 DNA replication factor

Andrei L Okorokov, Alastair Waugh, Julie Hodgkinson, Andal Murthy, Hye Kyung Hong, Elisabetta Leo, Michael B Sherman, Kai Stoeber, Elena V Orlova, Gareth H Williams

EMBO Rep. 2007 Oct; 8(10): 925–930. Published online 2007 Sep 7. doi: 10.1038/sj.embor.7401064

PMCID:: PMC2002553

Abstract Article PDF–352K

Select item 199570917.

Human Mcm10 Regulates the Catalytic Subunit of DNA Polymerase-α and Prevents DNA Damage during Replication

Sharbani Chattopadhyay, Anja-Katrin Bielinsky

Mol Biol Cell. 2007 Oct; 18(10): 4085–4095. doi: 10.1091/mbc.E06-12-1148

PMCID:: PMC1995709

Abstract Article PDF–1.3M

Select item 851443918.

BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage

Zhihua Kang, Pan Fu, Allen L. Alcivar, Haiqing Fu, Christophe Redon, Tzeh Keong Foo, Yamei Zuo, Caiyong Ye, Ryan Baxley, Advaitha Madireddy, Remi Buisson, Anja-Katrin Bielinsky, Lee Zou, Zhiyuan Shen, Mirit I. Aladjem, Bing Xia

Nat Commun. 2021; 12: 5966. Published online 2021 Oct 13. doi: 10.1038/s41467-021-26227-6

PMCID:: PMC8514439

Abstract Article PDF–2.6M

Select item 682630419.

Prognostic significance of minichromosome maintenance mRNA expression in human lung adenocarcinoma

Shu Li, Zhou Jiang, Yirun Li, Yang Xu

Oncol Rep. 2019 Dec; 42(6): 2279–2292. Published online 2019 Sep 23. doi: 10.3892/or.2019.7330

PMCID:: PMC6826304

Abstract Article PDF–1.7M

Select item 554603920.

The Mcm2–7-interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing

Masako Izumi, Takeshi Mizuno, Ken-ichiro Yanagi, Kazuto Sugimura, Katsuzumi Okumura, Naoko Imamoto, Tomoko Abe, Fumio Hanaoka

J Biol Chem. 2017 Aug 4; 292(31): 13008–13021. Published online 2017 Jun 22. doi: 10.1074/jbc.M117.779371

PMCID:: PMC5546039

Abstract Article PDF–1.2M

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