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Select item 72869091.

SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response

Huimin Liu, Siqi Xie, Fang Fang, Dhananjaya V. Kalvakolanu, Weihua Xiao

Cell Death Dis. 2020 Jun; 11(6): 445. Published online 2020 Jun 10. doi: 10.1038/s41419-020-2656-0

PMCID:: PMC7286909

Abstract Article PDF–2.3M

Select item 61891092.

SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival

Hexiu Su, Juncheng Hu, Liang Huang, Yang Yang, Morgan Thenoz, Anna Kuchmiy, Yufeng Hu, Peng Li, Hui Feng, Yu Zhou, Tom Taghon, Pieter Van Vlierberghe, Guoliang Qing, Zhichao Chen, Hudan Liu

Nat Commun. 2018; 9: 4281. Published online 2018 Oct 15. doi: 10.1038/s41467-018-06523-4

PMCID:: PMC6189109

Abstract Article PDF–3.7M

Select item 57025683.

Inherited SHQ1 mutations impair interaction with NAP57/dyskerin, a major target in dyskeratosis congenita

Jonathan Bizarro, U. Thomas Meier

Mol Genet Genomic Med. 2017 Nov; 5(6): 805–808. Published online 2017 Aug 15. doi: 10.1002/mgg3.314

PMCID:: PMC5702568

Abstract Article PDF–554K

Select item 43236274.

Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1

Mahavir Singh, Zhonghua Wang, Duilio Cascio, Juli Feigon

J Mol Biol. Author manuscript; available in PMC 2016 Feb 27.

Published in final edited form as: J Mol Biol. 2015 Feb 27; 427(4): 807–823. Published online 2014 Dec 29. doi: 10.1016/j.jmb.2014.12.012

PMCID:: PMC4323627

Abstract Article PDF–2.6M

Select item 26855185.

SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs

Petar N. Grozdanov, Sujayita Roy, Nupur Kittur, U. Thomas Meier

RNA. 2009 Jun; 15(6): 1188–1197. doi: 10.1261/rna.1532109

PMCID:: PMC2685518

Abstract Article PDF–773K

Select item 31695726.

GRIM-1, a Novel Growth Suppressor, Inhibits rRNA Maturation by Suppressing Small Nucleolar RNAs

Shreeram C. Nallar, Limei Lin, Varsha Srivastava, Padmaja Gade, Edward R. Hofmann, Hafiz Ahmed, Sekhar P. Reddy, Dhananjaya V. Kalvakolanu

PLoS One. 2011; 6(9): e24082. Published online 2011 Sep 8. doi: 10.1371/journal.pone.0024082

PMCID:: PMC3169572

Abstract Article PDF–1.4M

Select item 32229057.

The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic

Hélène Walbott, Rosario Machado-Pinilla, Dominique Liger, Magali Blaud, Stéphane Réty, Petar N. Grozdanov, Kate Godin, Herman van Tilbeurgh, Gabriele Varani, U. Thomas Meier, Nicolas Leulliot

Genes Dev. 2011 Nov 15; 25(22): 2398–2408. doi: 10.1101/gad.176834.111

PMCID:: PMC3222905

Abstract Article PDF–1.6M

Select item 43291438.

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1

Adam Freund, Franklin L. Zhong, Andrew S. Venteicher, Zhaojing Meng, Timothy D. Veenstra, Judith Frydman, Steven E. Artandi

Cell. Author manuscript; available in PMC 2015 Dec 4.

Published in final edited form as: Cell. 2014 Dec 4; 159(6): 1389–1403. Published online 2014 Nov 20. doi: 10.1016/j.cell.2014.10.059

PMCID:: PMC4329143

Abstract Article PDF–1.4M

Select item 45461229.

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

Yu Hasegawa, Deanne Taylor, Dmitry A. Ovchinnikov, Ernst J. Wolvetang, Laurence de Torrenté, Jessica C. Mar

PLoS Genet. 2015 Aug; 11(8): e1005428. Published online 2015 Aug 19. doi: 10.1371/journal.pgen.1005428

PMCID:: PMC4546122

Abstract Article PDF–4.3M

Select item 886469510.

Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications

Antonieta L. Salguero, Maggie Chen, Aaron T. Balana, Nam Chu, Hanjie Jiang, Brad A. Palanski, Hwan Bae, Katharine M. Wright, Sara Nathan, Heng Zhu, Sandra B. Gabelli, Matthew R. Pratt, Philip A. Cole

ACS Chem Biol. Author manuscript; available in PMC 2022 Feb 23.

Published in final edited form as: ACS Chem Biol. 2022 Jan 21; 17(1): 68–76. Published online 2021 Dec 23. doi: 10.1021/acschembio.1c00632

PMCID:: PMC8864695

Abstract Article PDF–1.1M

Select item 546003511.

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

Philippe Cloutier, Christian Poitras, Mathieu Durand, Omid Hekmat, Émilie Fiola-Masson, Annie Bouchard, Denis Faubert, Benoit Chabot, Benoit Coulombe

Nat Commun. 2017; 8: 15615. Published online 2017 May 31. doi: 10.1038/ncomms15615

PMCID:: PMC5460035

Abstract Article PDF–2.9M

Select item 804593212.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 271642213.

Defining the Human Deubiquitinating Enzyme Interaction Landscape

Mathew E. Sowa, Eric J. Bennett, Steven P. Gygi, J. Wade Harper

Cell. Author manuscript; available in PMC 2010 Jul 23.

Published in final edited form as: Cell. 2009 Jul 23; 138(2): 389–403. Published online 2009 Jul 16. doi: 10.1016/j.cell.2009.04.042

PMCID:: PMC2716422

Abstract Article PDF–6.1M

Select item 268304714.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 874895815.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 910523516.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 835296417.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 476457318.

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning

Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich

eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466

PMCID:: PMC4764573

Abstract Article PDF–5.7M

Select item 889702219.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

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