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Select item 109319221.

Familial Dilated Cardiomyopathy: A Novel MED9 Short Isoform Identification

Monica Franzese, Mario Zanfardino, Andrea Soricelli, Annapaola Coppola, Ciro Maiello, Marco Salvatore, Concetta Schiano, Claudio Napoli

Int J Mol Sci. 2024 Mar; 25(5): 3057. Published online 2024 Mar 6. doi: 10.3390/ijms25053057

PMCID:: PMC10931922

Abstract Article PDF–12M

Select item 29202862.

CDK8 is a positive regulator of transcriptional elongation within the serum response network

Aaron J. Donner, Christopher C. Ebmeier, Dylan J. Taatjes, Joaquín M. Espinosa

Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Aug 11.

Published in final edited form as: Nat Struct Mol Biol. 2010 Feb; 17(2): 194–201. Published online 2010 Jan 24. doi: 10.1038/nsmb.1752

PMCID:: PMC2920286

Abstract Article PDF–2.1M

Select item 1865943.

Genes in a Refined Smith-Magenis Syndrome Critical Deletion Interval on Chromosome 17p11.2 and the Syntenic Region of the Mouse

Weimin Bi, Jiong Yan, Paweł Stankiewicz, Sung-Sup Park, Katherina Walz, Cornelius F. Boerkoel, Lorraine Potocki, Lisa G. Shaffer, Koen Devriendt, Małgorzata J.M. Nowaczyk, Ken Inoue, James R. Lupski

Genome Res. 2002 May; 12(5): 713–728. doi: 10.1101/gr.73702

PMCID:: PMC186594

Abstract Article PDF–611K

Select item 35663074.

The SCF–Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator

Michael A. Davis, Elizabeth A. Larimore, Brian M. Fissel, Jherek Swanger, Dylan J. Taatjes, Bruce E. Clurman

Genes Dev. 2013 Jan 15; 27(2): 151–156. doi: 10.1101/gad.207720.112

PMCID:: PMC3566307

Abstract Article PDF–1.2M

Select item 47021035.

The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety

Sang Jun Han, Khurshida Begum, Charles E. Foulds, Ross A. Hamilton, Suzanna Bailey, Anna Malovannaya, Doug Chan, Jun Qin, Bert W. O’Malley

Mol Pharmacol. 2016 Jan; 89(1): 14–26. Published online 2016 Jan. doi: 10.1124/mol.115.100925

PMCID:: PMC4702103

Abstract Article PDF–1.6M

Select item 51049376.

Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin

Roy Baas, Ayestha Sijm, Hetty A. A. M. van Teeffelen, Robert van Es, Harmjan R. Vos, H. Th. Marc Timmers

J Biol Chem. 2016 Nov 11; 291(46): 24121–24132. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748582

PMCID:: PMC5104937

Abstract Article PDF–4.4M

Select item 10840417.

Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

Gerhard Mittler, Elisabeth Kremmer, H. Th. Marc Timmers, Michael Meisterernst

EMBO Rep. 2001 Sep 15; 2(9): 808–813. doi: 10.1093/embo-reports/kve186

PMCID:: PMC1084041

Abstract Article PDF–413K

Select item 41049648.

Subunit architecture and functional modular rearrangements of the transcriptional Mediator complex

Kuang-Lei Tsai, Chieri Tomomori-Sato, Shigeo Sato, Ronald C. Conaway, Joan W. Conaway, Francisco J. Asturias

Cell. Author manuscript; available in PMC 2015 Jun 5.

Published in final edited form as: Cell. 2014 Jun 5; 157(6): 1430–1444. Published online 2014 May 29. doi: 10.1016/j.cell.2014.05.015

Correction in:: volume 158 on page 463

PMCID:: PMC4104964

Abstract Article PDF–939K

Select item 28239229.

Streamlined analysis schema for high-throughput identification of endogenous protein complexes

Anna Malovannaya, Yehua Li, Yaroslava Bulynko, Sung Yun Jung, Yi Wang, Rainer B. Lanz, Bert W. O’Malley, Jun Qin

Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6): 2431–2436. Published online 2010 Jan 22. doi: 10.1073/pnas.0912599106

Correction in:: Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13): 6118.

PMCID:: PMC2823922

Abstract Article PDF–566K

Select item 314532510.

Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors

Hidehisa Takahashi, Tari J. Parmely, Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin-Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald C. Conaway, Joan W. Conaway

Cell. Author manuscript; available in PMC 2012 Jul 8.

Published in final edited form as: Cell. 2011 Jul 8; 146(1): 92–104. doi: 10.1016/j.cell.2011.06.005

PMCID:: PMC3145325

Abstract Article PDF–1.9M

Select item 910630311.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 642645512.

Mapping the genetic landscape of human cells

Max A. Horlbeck, Albert Xu, Min Wang, Neal K. Bennett, Chong Y. Park, Derek Bogdanoff, Britt Adamson, Eric D. Chow, Martin Kampmann, Tim R. Peterson, Ken Nakamura, Michael A. Fischbach, Jonathan S. Weissman, Luke A. Gilbert

Cell. Author manuscript; available in PMC 2019 Aug 9.

Published in final edited form as: Cell. 2018 Aug 9; 174(4): 953–967.e22. Published online 2018 Jul 19. doi: 10.1016/j.cell.2018.06.010

PMCID:: PMC6426455

Abstract Article PDF–3.6M

Select item 810809313.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 637572914.

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains

Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras

Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006

PMCID:: PMC6375729

Abstract Article PDF–10M

Select item 438371315.

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

Jean-Philippe Lambert, Monika Tucholska, Christopher Go, James D.R. Knight, Anne-Claude Gingras

J Proteomics. Author manuscript; available in PMC 2016 Apr 6.

Published in final edited form as: J Proteomics. 2015 Apr 6; 118: 81–94. Published online 2014 Oct 2. doi: 10.1016/j.jprot.2014.09.011

PMCID:: PMC4383713

Abstract Article PDF–1.4M

Select item 1110948316.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 545599617.

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

Cell Syst. Author manuscript; available in PMC 2017 Sep 28.

Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001

PMCID:: PMC5455996

Abstract Article PDF–3.1M

Select item 642009718.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

Select item 319082619.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907